KR20100097098A - 레티놀 관련 질환을 치료하기 위한 방법 및 화합물 - Google Patents

레티놀 관련 질환을 치료하기 위한 방법 및 화합물 Download PDF

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Publication number
KR20100097098A
KR20100097098A KR1020107009129A KR20107009129A KR20100097098A KR 20100097098 A KR20100097098 A KR 20100097098A KR 1020107009129 A KR1020107009129 A KR 1020107009129A KR 20107009129 A KR20107009129 A KR 20107009129A KR 20100097098 A KR20100097098 A KR 20100097098A
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KR
South Korea
Prior art keywords
alkyl
compound
optionally substituted
formula
butyl
Prior art date
Application number
KR1020107009129A
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English (en)
Korean (ko)
Inventor
나탄 엘 마타
킴 비 판
탐 브이 부이
무스타파 하다치
Original Assignee
리비젼 쎄러퓨틱스, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 리비젼 쎄러퓨틱스, 인크. filed Critical 리비젼 쎄러퓨틱스, 인크.
Publication of KR20100097098A publication Critical patent/KR20100097098A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020107009129A 2007-09-27 2008-09-16 레티놀 관련 질환을 치료하기 위한 방법 및 화합물 KR20100097098A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US97576507P 2007-09-27 2007-09-27
US60/975,765 2007-09-27
US98132207P 2007-10-19 2007-10-19
US60/981,322 2007-10-19

Publications (1)

Publication Number Publication Date
KR20100097098A true KR20100097098A (ko) 2010-09-02

Family

ID=40512081

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107009129A KR20100097098A (ko) 2007-09-27 2008-09-16 레티놀 관련 질환을 치료하기 위한 방법 및 화합물

Country Status (8)

Country Link
EP (1) EP2205234A4 (fr)
JP (1) JP2010540541A (fr)
KR (1) KR20100097098A (fr)
CN (1) CN101873852A (fr)
AU (1) AU2008305303A1 (fr)
CA (1) CA2699773A1 (fr)
IL (1) IL204728A0 (fr)
WO (1) WO2009042444A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8586571B2 (en) 2007-10-18 2013-11-19 Takeda Pharmaceutical Company Limited Heterocyclic compound
WO2010119992A1 (fr) 2009-04-16 2010-10-21 Takeda Pharmaceutical Company Limited Dérivés de n-acyl-n'-phénylpipérazine utiles (notamment) pour la prévention ou le traitement du diabète
US8980924B2 (en) 2010-11-24 2015-03-17 The Trustees Of Columbia University In The City Of New York Non-retinoid RBP4 antagonist for treatment of age-related macular degeneration and stargardt disease
KR20140001224A (ko) * 2010-12-02 2014-01-06 다이이찌 산쿄 가부시키가이샤 수식 1 개 사슬 폴리뉴클레오티드
US9333202B2 (en) 2012-05-01 2016-05-10 The Trustees Of Columbia University In The City Of New York Non-retinoid antagonists for treatment of age-related macular degeneration and stargardt disease
EP2968304B1 (fr) 2013-03-14 2018-10-10 The Trustees of Columbia University in the City of New York 4-phénylpipéridines, leur préparation et leur utilisation
US9637450B2 (en) 2013-03-14 2017-05-02 The Trustees Of Columbia University In The City Of New York Octahydrocyclopentapyrroles, their preparation and use
US9938291B2 (en) 2013-03-14 2018-04-10 The Trustess Of Columbia University In The City Of New York N-alkyl-2-phenoxyethanamines, their preparation and use
US9944644B2 (en) 2013-03-14 2018-04-17 The Trustees Of Columbia University In The City Of New York Octahydropyrrolopyrroles their preparation and use
BR112016025356B1 (pt) 2014-04-30 2023-04-18 The Trustees Of Columbia University In The City Of New York Compostos de 4-fenilpiperidinas substituídas, composições e seus usos
US9944596B2 (en) * 2014-10-24 2018-04-17 Takeda Pharmaceutical Company Limited Heterocyclic compound
CN115197160A (zh) 2014-10-24 2022-10-18 武田药品工业株式会社 杂环化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2526534A (en) * 1948-07-03 1950-10-17 Dow Chemical Co Di-(aryloxy)-methanes
US4255152A (en) * 1978-09-05 1981-03-10 Ciba-Geigy Corporation Process for the dyeing of hydrophobic fibres
JPS577480A (en) * 1980-06-16 1982-01-14 Sankyo Co Ltd 4-alkoxy-6-phenoxymethyl-2-pyrone derivative
WO2005070126A2 (fr) * 2004-01-08 2005-08-04 The Regents Of The University Of Colorado Systemes et procedes pour le traitement de maladies inflammatoires et proliferantes humaines, et des plaies avec le gene ucp et/ou l'anticorps anti-fas ou autre inhibiteur, eventuellement avec un inhibiteur du metabolisme d'acide gras et/ou un inhibiteur du metabolisme de glucose et applications associees
WO2005092062A2 (fr) * 2004-03-19 2005-10-06 Myriad Genetics, Inc. Composes destines aux troubles neurodegeneratifs
WO2005116010A1 (fr) * 2004-05-26 2005-12-08 Merck Frosst Canada Ltd. Agoniste du recepteur ep4, compositions et methodes associees ep4 receptor agonist, compositions and methods thereof

Also Published As

Publication number Publication date
EP2205234A2 (fr) 2010-07-14
CN101873852A (zh) 2010-10-27
JP2010540541A (ja) 2010-12-24
AU2008305303A1 (en) 2009-04-02
WO2009042444A2 (fr) 2009-04-02
CA2699773A1 (fr) 2009-04-02
EP2205234A4 (fr) 2010-12-22
IL204728A0 (en) 2010-11-30
WO2009042444A3 (fr) 2009-05-14

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