CA2699773A1 - Procedes et composes pour le traitement de maladies liees au retinol - Google Patents

Procedes et composes pour le traitement de maladies liees au retinol Download PDF

Info

Publication number
CA2699773A1
CA2699773A1 CA2699773A CA2699773A CA2699773A1 CA 2699773 A1 CA2699773 A1 CA 2699773A1 CA 2699773 A CA2699773 A CA 2699773A CA 2699773 A CA2699773 A CA 2699773A CA 2699773 A1 CA2699773 A1 CA 2699773A1
Authority
CA
Canada
Prior art keywords
alkyl
compound
formula
optionally substituted
butyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2699773A
Other languages
English (en)
Inventor
Nathan L. Mata
Kim B. Phan
Tam V. Bui
Mustapha Haddach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sirion Therapeutics Inc
Original Assignee
Sirion Therapeutics, Inc.
Nathan L. Mata
Kim B. Phan
Tam V. Bui
Mustapha Haddach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sirion Therapeutics, Inc., Nathan L. Mata, Kim B. Phan, Tam V. Bui, Mustapha Haddach filed Critical Sirion Therapeutics, Inc.
Publication of CA2699773A1 publication Critical patent/CA2699773A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
CA2699773A 2007-09-27 2008-09-16 Procedes et composes pour le traitement de maladies liees au retinol Abandoned CA2699773A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US97576507P 2007-09-27 2007-09-27
US60/975,765 2007-09-27
US98132207P 2007-10-19 2007-10-19
US60/981,322 2007-10-19
PCT/US2008/076499 WO2009042444A2 (fr) 2007-09-27 2008-09-16 Procédés et composés pour le traitement de maladies liées au rétinol

Publications (1)

Publication Number Publication Date
CA2699773A1 true CA2699773A1 (fr) 2009-04-02

Family

ID=40512081

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2699773A Abandoned CA2699773A1 (fr) 2007-09-27 2008-09-16 Procedes et composes pour le traitement de maladies liees au retinol

Country Status (8)

Country Link
EP (1) EP2205234A4 (fr)
JP (1) JP2010540541A (fr)
KR (1) KR20100097098A (fr)
CN (1) CN101873852A (fr)
AU (1) AU2008305303A1 (fr)
CA (1) CA2699773A1 (fr)
IL (1) IL204728A0 (fr)
WO (1) WO2009042444A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8586571B2 (en) 2007-10-18 2013-11-19 Takeda Pharmaceutical Company Limited Heterocyclic compound
EP2419413B1 (fr) * 2009-04-16 2016-11-23 Takeda Pharmaceutical Company Limited Derives de n-acyl-n'-phenylpiperazine utiles, entres autres, pour la prevention ou le traitement du diabete
WO2012071369A2 (fr) * 2010-11-24 2012-05-31 The Trustees Of Columbia University In The City Of New York Antagoniste rbp4 non rétinoïde pour le traitement de la dégénérescence maculaire liée à l'âge et de la maladie de stargardt
ES2664992T3 (es) * 2010-12-02 2018-04-24 Daiichi Sankyo Company, Limited Polinucleótido monocatenario modificado
WO2013166037A1 (fr) 2012-05-01 2013-11-07 The Trustees Of Columbia University In The City Of New York Antagonistes non rétinoïdes pour le traitement de troubles oculaires
WO2014151959A1 (fr) 2013-03-14 2014-09-25 The Trustees Of Columbia University In The City Of New York N-alkyl-2-phénoxyéthanamines, leurs préparation et utilisation
US10273243B2 (en) 2013-03-14 2019-04-30 The Trustees Of Columbia University In The City Of New York 4-phenylpiperidines, their preparation and use
US9944644B2 (en) 2013-03-14 2018-04-17 The Trustees Of Columbia University In The City Of New York Octahydropyrrolopyrroles their preparation and use
ES2700541T3 (es) 2013-03-14 2019-02-18 Univ Columbia Octahidrociclopentapirroles, su preparación y uso
CN106794364B (zh) 2014-04-30 2019-12-24 哥伦比亚大学董事会 取代的4-苯基哌啶及其制备和用途
WO2016063934A1 (fr) * 2014-10-24 2016-04-28 武田薬品工業株式会社 Composé hétérocyclique
KR102490156B1 (ko) 2014-10-24 2023-01-18 다케다 야쿠힌 고교 가부시키가이샤 헤테로시클릭 화합물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2526534A (en) * 1948-07-03 1950-10-17 Dow Chemical Co Di-(aryloxy)-methanes
US4255152A (en) * 1978-09-05 1981-03-10 Ciba-Geigy Corporation Process for the dyeing of hydrophobic fibres
JPS577480A (en) * 1980-06-16 1982-01-14 Sankyo Co Ltd 4-alkoxy-6-phenoxymethyl-2-pyrone derivative
US7510710B2 (en) * 2004-01-08 2009-03-31 The Regents Of The University Of Colorado Compositions of UCP inhibitors, Fas antibody, a fatty acid metabolism inhibitor and/or a glucose metabolism inhibitor
WO2005092062A2 (fr) * 2004-03-19 2005-10-06 Myriad Genetics, Inc. Composes destines aux troubles neurodegeneratifs
WO2005116010A1 (fr) * 2004-05-26 2005-12-08 Merck Frosst Canada Ltd. Agoniste du recepteur ep4, compositions et methodes associees ep4 receptor agonist, compositions and methods thereof

Also Published As

Publication number Publication date
EP2205234A4 (fr) 2010-12-22
EP2205234A2 (fr) 2010-07-14
KR20100097098A (ko) 2010-09-02
CN101873852A (zh) 2010-10-27
AU2008305303A1 (en) 2009-04-02
WO2009042444A3 (fr) 2009-05-14
IL204728A0 (en) 2010-11-30
JP2010540541A (ja) 2010-12-24
WO2009042444A2 (fr) 2009-04-02

Similar Documents

Publication Publication Date Title
US7973079B2 (en) Methods and compounds for treating retinol-related diseases
CA2699773A1 (fr) Procedes et composes pour le traitement de maladies liees au retinol
CA2569691C (fr) Methodes et compositions pour traitement de manifestations ophtalmiques au moyen de derives de retinyl
CA2614627C (fr) Methodes et compositions de traitement de maladies ophtalmiques par la modulation du retinol serique, de la proteine de liaison de retinol serique (rbp) et / ou de la rbp / du retinol serique
US20080254140A1 (en) Combination Methods and Therapies for Treating Opthalmic Conditions with 13-Cis-Retinyl Derivatives

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20140916