KR20090059148A - 쿠프레독신 유래된 펩티드의 변형 및 이의 이용 방법 - Google Patents

쿠프레독신 유래된 펩티드의 변형 및 이의 이용 방법 Download PDF

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KR20090059148A
KR20090059148A KR1020097007180A KR20097007180A KR20090059148A KR 20090059148 A KR20090059148 A KR 20090059148A KR 1020097007180 A KR1020097007180 A KR 1020097007180A KR 20097007180 A KR20097007180 A KR 20097007180A KR 20090059148 A KR20090059148 A KR 20090059148A
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타파스 다스 구프타
아난다 차카라바티
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더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이
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Abstract

본 발명에서는 향상된 약동학적 특성을 갖는 약리 활성의 변형된 쿠프레독신 유래된 펩티드 및 이들 약리 활성에 관련된 다양한 장애로 고통받는 포유동물을 치료하기 위하여 이들을 이용하는 방법을 제시한다. 쿠프레독신 유래된 펩티드의 변형에는 이들 펩티드의 혈장 반감기(plasma half-life)를 증가시키고, 약리 활성의 고유 활성(specific activity)을 증가시키고, 면역원성(immunogenicity)을 감소시키고, 펩티드의 생체내변화(biotransformation)를 감소시키는 아미노산 서열 변이와 구조 유도(structural derivation)가 포함된다. 변형된 쿠프레독신 유래된 펩티드는 포유동물에서 암, 부적절한 혈관신생에 관련된 장애, 바이러스와 세균, 특히, HIV와 말라리아 감염, 에프린 신호전달에 관련된 장애를 치료하고, 진단 화합물을 비롯한 화물 화합물(cargo compound)을 암 세포에 전달하는 방법에 이용될 수 있다.
쿠프레독신

Description

쿠프레독신 유래된 펩티드의 변형 및 이의 이용 방법{MODIFICATION OF CUPREDOXIN DERIVED PEPTIDES AND METHODS OF USE THEREOF}
관련된 출원에 대한 교차 참조
본 출원은 35 U.S.C. §§ 119와 120 하에, 2006년 9월 11일 제출된 U.S. 가출원 No. 60/843,388에 우선권을 주장하고, 상기 출원은 2005년 10월 6일 제출된 U.S. 특허 출원 No. 11/244,105에 우선권을 주장하고, 상기 출원은 2004년 10월 7일 제출된 U.S. 가출원 No. 60/616,782, 2005년 5월 13일 제출된 U.S. 가출원 No. 60/680,500 및 2005년 7월 19일 제출된 U.S. 가출원 No. 60/700,297에 우선권을 주장한다. 이들 출원의 전체 내용은 본 명세서에 참조로서 편입된다.
정부 권리의 진술
본 출원의 요부는 National Institutes of Health (NIH), Bethesda, Maryland, U.S.A.로부터 연구 기금(Grant Number ES 04050-18)을 지원받았다. 정부는 본 발명에 일부 권리를 주장할 수 있다.
본 발명의 기술 분야
본 발명은 향상된 약동학적 특성을 갖는 약리 활성의 변형된 쿠프레독신 유래된 펩티드 및 이들 약리 활성에 관련된 다양한 장애로 고통받는 포유동물을 치료하기 위하여 이들을 이용하는 방법에 관계한다. 쿠프레독신 유래된 펩티드의 변형 에는 이들 펩티드의 혈장 반감기(plasma half-life)를 증가시키고, 약리 활성의 고유 활성(specific activity)을 증가시키고, 면역원성(immunogenicity)을 감소시키고, 펩티드의 생체내변화(biotransformation)를 감소시키는 아미노산 서열 변이와 구조 유도(structural derivation)가 포함된다. 변형된 쿠프레독신 유래된 펩티드는 포유동물에서 암, 부적절한 혈관신생에 관련된 장애, 바이러스와 세균, 특히, HIV와 말라리아 감염, 에프린 신호전달에 관련된 장애를 치료하고, 진단 화합물을 비롯한 화물 화합물(cargo compound)을 암 세포에 전달하는 방법에 이용될 수 있다.
녹농균(Pseudomonas aeruginosa)으로부터 쿠프레독신 아주린은 유망하고 새로운 치료와 진단 분자이다. 녹농균(P. aeruginosa)에 의해 만들어지는 2가지 산화 환원 단백질(redox protein), 쿠프레독신 아주린과 시토크롬(cytochrome) c551(Cyt c551)은 둘 모두 J774 세포 내로 들어가고 정상 세포와 비교하여 인간 암 세포를 지향하는 현저한 세포독성 활성(cytotoxic activity)을 나타낸다(Zaborina et al., Microbiology 146: 2521-2530 (2000)). 아주린은 또한, 인간 흑색종 UISO-Mel-2 또는 인간 유방암 MCF-7 세포 내로 들어갈 수 있다(Yamada et al., PNAS 99:14098-14103 (2002); Punj et al., Oncogene 23:2367-2378 (2004); Yamada et al., Cell. Biol. 7:14181431 (2005)). 이에 더하여, 녹농균(P. aeruginosa)으로부터 아주린은 선호적으로 J774 뮤린 세망 세포(reticulum cell) 육종 세포 내로 들어가고, 종양 억제 단백질(tumor suppressor protein) p53와 복합체를 형성하여 안정화시키고, p53의 세포내 농도를 강화시키고, 아폽토시스(apoptosis)를 유도한다(Yamada et al., Infection and Immunity, 70:7054-7062 (2002)). 아주린은 또한, 비-암성 세포와 비교하여 인간 골육종(osteosarcoma) 세포에서 아폽토시스의 현저한 증가를 유도하였다(Ye et al., Ai Zheng 24:298-304 (2003)). 티오바실루스 페로옥시단스(Thiobacillus ferrooxidans)롤부터 루스티시아닌 역시 대식세포 내로 들어가 아폽토시스를 유도할 수 있다(Yamada et al., Cell Cycle 3:1182-1187 (2004); Yamada et al., Cell. Micro. 7:1418-1431 (2005)). 포르미디움 라미노슘(Phormidium laminosum)으로부터 플라스토시아닌과 아크로모박터 시클로클라스테스(Achromobacter cycloclastes)로부터 슈도아주린 역시 대식세포에 대한 세포독성을 나타낸다(U.S. Pat. Pub. No. 20060040269; 2006년 2월 23일 공개).
아주린은 현재, 치료적으로 중요한 다른 약리 활성을 갖는 것으로 알려져 있다. 이는 인간 배꼽 혈관 내피 세포(umbilical vascular endothelium cell, HUVEC)에서 혈관신생을 저해하는 것으로 알려져 있다(U.S. Patent Application No. 11/488,693; 2006년 7월 19일 제출). 녹농균(P. aeruginosa)으로부터 아주린은 또한, 말초혈 단핵 세포(peripheral blood mononuclear cell)에서 HIV-1 감염의 성장을 저해하고 말라리아-감염된 포유동물 적혈구 세포의 기생충혈증(parasistemia)를 저해하는 능력으로 알려져 있다(Chaudhari et al., Cell Cycle. 5: 1642-1648 (2006)). 녹농균(P. aeruginosa)으로부터 아주린은 또한, 다양한 포유동물 세포와 조직에서 에프린 신호전달 체계(ephrin signaling system)를 간섭하는 것으로 알려 져 있다(U.S. Patent Application No. 11/436,592;2006년 5월 19일 제출).
이런 이유로, 아주린, 특히, 아주린으로부터 유래된 2개의 펩티드, 18-mer과 28-mer은 치료와 진단에 유용한 것으로 밝혀졌다. 하지만, 환자의 체내에서 치료제(therapeutic agent)의 효능은 여러 인자에 좌우된다. 치료 약물 자체의 활성 이외에, 이러한 치료 약물의 약동학적 특성 및 상기 약물이 투여된 이후 진행되는 다양한 과정, 다시 말하면, 흡수(absorption), 분포(distribution), 물질대사(metabolism)와 배출(excretion)과의 관계 역시 존재한다. 약물의 이와 같은 약동학적 특성은 이들 생리학적 과정이 투여된 약물의 효능에 어떻게, 그리고 어느 정도 영향을 주는 지를 설명하는데, 이들 특성에는 혈류(blood stream) 내에서 약물 반감기(drug half-life), 약물의 간 일차-패스 물질대사(hepatic first-pass metabolism), 약물의 체적 분포(volume distribution), 약물의 알부민 결합(albumin binding)의 정도 등이 포함된다. 이들 약동학적 특성 각각은 약물의 효능에 심대한 영향을 줄 수 있다.
약물의 환자의 혈류 내로의 흡수 부위는 투여 경로에 좌우된다. 가령, 경구 투여된 약물은 이러한 약물의 화학적, 물리적 성격으로 인하여, 다른 부위에서보다 소화관(alimentary tract)의 한 부위에서 더욱 많이 흡수된다. 다른 한편, 비경구 투여(parenteral administration) 투여에 의한 흡수는 경구 투여(oral administration)보다 신속할 뿐만 아니라 약물의 혈액 수준(blood level)이 훨씬 예측가능한데, 그 이유는 특히, 정맥내 투여(intravenous administration)에서 훨씬 적은 양의 약물이 특히, 상실되기 때문이다. 생체이용효율(bioavailability)은 대순환(systemic circulation)에 도달하는 투여된 약물 중에서 소량이다.
혈류로부터 조직의 세포외액(extracelluar fluid)(간질(interstitium)) 및/또는 세포 내로 약물의 분포는 약물의 다양한 측면에 의해 변화될 수 있다. 체내에서 약물의 분포는 "약물의 체적 분포"로서 표시되는데, 이는 약물이 전달되는 체액의 가상 체적(hypothetical volume)이다. 약물의 구조는 소수성 약물이 대부분의 생물막(biological membrane)을 더욱 용이하게 통과하고, 따라서 조직의 세포 내에 분포될 수 있다는 점에서, 약물 분포(drug distribution)에 영향을 줄 수 있다. 약물은 또한, 혈액 단백질(blood protein)에 결합되어, 주변 조직(surrounding tissue)으로 통과가 지연될 수도 있다. 가령, 혈류 내에서 나프록센(naproxen)은 혈장 단백질(plasma protein)에 99% 결합되고, 페니실린(penicillin) G는 60% 결합되고, 아목시실린(amoxicillin)은 단지 20%만 결합되고, 미녹시딜(minoxidil)은 결합되지 않는다(Howard C. Ansel et al., Pharmaceutical Dosage Forms and Delivery Systems 129 (Lippincott, Williams and Wilkins 1999)). 결합된 약물은 신체 해독 과정(detoxification process)에 노출되지 않고, 신사구체(renal glomeruli)를 통한 여과에 의해 혈류로부터 제거되지도 않는다. 이러한 결합된 약물은 비활성 부분으로 지칭되는 반면, 결합되지 않은 부분은 활성 부분으로 간주된다. 약물의 결합된 부분은 유리 약물(free drug)의 수준이 단백질 포화(protein saturation)를 담보할 만큼 충분하지 않을 때 결합되지 않은 활성 형태로 혈류 내로 방출되는 약물의 저장고로서 기능한다. 이런 이유로, 혈류 내에서 결합된 약물은 더욱 오랜 기간 동안 체내에 존속하고, 더욱 적은 횟수의 투약을 요구할 것이 다.
환자 내에서 약물의 물질대사(metabolism) 역시 효능에 영향을 줄 것이다. 많은 약물은 체내에서 배출되기 이전에 생체내변화를 겪는다. 약물의 이러한 생체내변화는 더욱 강한 수용성, 더욱 강한 이온화, 혈장과 조직 내에서 단백질에 대한 더욱 약한 결합 능력, 더욱 약한 세포막 침입 능력 및 더욱 약화된 약리 활성을 나타내는 약물 형태를 결과할 수 있다. 이런 이유로, 생체내변화된 약물은 독성이 더욱 적고, 더욱 용이하게 배출될 수 있다. 약물이 생체내변화되는 4가지 주요한 방법이 존재한다: 산화(oxidation), 환원(reduction), 가수분해(hydrolysis)와 결합(conjugation). 산화 반응은 간세포 내에서 소포체(endoplasmic reticulum)에 결합된 산화효소(oxidase)에 의해 주로 촉매된다. 환원 반응은 장과 간 내에서 환원효소(reductase)에 의해 주로 촉매된다. 가수분해 파괴는 간 내에서 에스테라아제(esterase)에 의해 주로 촉매된다. 약물의 생체내변화의 가장 일반적인 경로인 글루쿠로니드 결합(glucuronide conjugation)은 약물과 글루쿠론산(glucuronic acid)의 결합에 의해 진행되고, 신체로부터 쉽게 제거되는 상기 약물의 이온 형태(ionic form)를 형성한다(Christensen et al., J. Pharm. Pharmacol. 37:91-95 (1985)). 제거를 증가시키는 다른 생체내 변화 과정(biotransformative process)에는 메틸화(methylation)와 아실화(acylation)가 포함된다.
신체로부터 약물의 배출은 다양한 경로에 의해 진행된다. 신장은 소변으로 약물을 제거하는데 주도적인 역할을 수행한다. 하지만, 약물은 간을 통하여 혈장으로부터 제거될 수도 있다. 특히, 경구 투여되는 약물의 경우에, 간이 약물의 혈장 반감기를 결정하는데 중요한 역할을 수행한다.
쿠프레독신의 약리 활성을 유지하면서 포유동물에서 향상된 약동학적 특성을 나타내는 쿠프레독신 유래된 펩티드가 요구된다. 특히, 환자의 체내에서 안정하고, 높은 특이적인 약리 활성을 유지하며, 긴 혈장 반감기를 갖는 쿠프레독신 유래된 펩티드가 치료제와 진단제로서 특히 유효할 것이다.
본 발명의 요약
본 발명의 한 측면에서는 쿠프레독신 유래된 펩티드의 변이체 또는 유도체인 분리되고 변형된 쿠프레독신 유래된 펩티드를 제시한다. 한 구체예에서, 분리되고 변형된 쿠프레독신 유래된 펩티드는 변형되지 않은 쿠프레독신 유래된 펩티드와 비교하여 향상된 약동학적 특성을 갖는다. 향상된 약동학적 특성은 (1) 환자에서 생체내변화(biotransformation)에 대한 감소된 민감성, (2) 더욱 늦은 속도로 환자의 신체로부터 배출, (3) 3차 구조(tertiary structure)의 증가된 안정성(stability), (4) 더욱 긴 혈장 반감기(plasma half-life) 중에서 한 가지 이상이다.
부가적으로, 분리되고 변형된 쿠프레독신 유래된 펩티드는 쿠프레독신의 최소한 하나의 약리 활성을 보유한다. 특이적인 약리 활성에는 (1) 포유동물 암 세포로 침입, (2) 비-암성 포유동물 세포로 침입하지 않음, (3) 전-악성 포유동물 세포로 침입, (4) 포유동물 암 세포 사멸, (5) 전-악성 포유동물 세포 사멸, (6) 포유동물 암 세포의 성장 저해, (7) HIV-1 감염 저해, (8) 말라리아-감염된 적혈구 세포의 기생충혈증 저해, (9) 에프린 신호전달 체계(ephrin signaling system) 간섭, (10) 혈관신생 저해가 포함된다.
분리되고 변형된 쿠프레독신 유래된 펩티드는 녹농균(Pseudomonas aeruginosa), 포르미디움 라미노섬(Phormidium laminosum), 울바 퍼투씨스(Ulva pertussis), 티오바실루스 페로옥시단스(Thiobacillus ferrooxidans), 아크로모박터 시클로클라스테스(Achromobacter cycloclastes), 슈도모나스 시린가에(Pseudomonas syringae), 수막염균(Neisseria meningitidis), 장염 비브리오(Vibrio parahaemolyticus), 보르데텔라 브론키셉티카(Bordetella bronchiseptica), 백일해(Bordetella pertussis), 클로로플렉서스 아우란티아쿠스(Chloroflexus aurantiacus) 또는 임균(Neisseria gonorrhoeae)에서 선택되는 생물체로부터 쿠프레독신으로부터 유래된다. 쿠프레독신은 아주린(azurin), 플라스토시아닌(plastocyanin), 루스티시아닌(rusticyanin), 슈도아주린(pseudoazurin), 아우라시아닌(auracyanin), 스텔라시아닌(stellacyanin), 오이 기초 단백질(cucumber basic protein) 또는 아주린-유사 단백질이다. 특정 구체예에서, 쿠프레독신은 SEQ ID NO: 1-12 중에서 하나이다. 분리되고 변형된 쿠프레독신 유래된 펩티드는 쿠프레독신의 절두이다. 특정 구체예에서, 펩티드는 SEQ ID NO: 13-47 중에서 하나이다. 다른 특정 구체예에서, SEQ ID NO: 1-12는 이러한 분리된 펩티드에 최소한 90 % 동일하다.
일부 구체예에서, 분리되고 변형된 쿠프레독신 유래된 펩티드는 가수분해에 더욱 적게 민감하다. 구체적으로, 이러한 분리된 펩티드는 쿠프레독신 유래된 펩티드의 서열 내에서 하나이상의 아스파라긴 또는 세린 잔기가 다른 아미노산 잔기, 구체적으로, 글루타민산 또는 트레오닌 잔기로 치환된다.
일부 구체예에서, 분리되고 변형된 쿠프레독신 유래된 펩티드는 탈아미드화(deamidation)에 더욱 적게 민감하다. 특정 구체예에서, 쿠프레독신 유래된 펩티드의 하나이상의 글리신 잔기가 다른 아미노산 잔기, 구체적으로, 트레오닌 또는 알라닌 잔기로 치환된다. 일부 구체예에서, 녹농균(Pseudomonas aeruginosa) 아주린(SEQ ID NO: 1)의 잔기 58 또는 63에 동등한 쿠프레독신 유래된 펩티드 내에서 하나이상의 글리신 잔기가 치환된다. 다른 특정 구체예에서, 이러한 분리된 펩티드는 SEQ ID NO: 30을 포함한다.
일부 구체예에서, 분리되고 변형된 쿠프레독신 유래된 펩티드는 산화에 더욱 적게 민감하다. 구체적으로, 이러한 분리된 펩티드는 쿠프레독신 유래된 펩티드의 하나이상의 메티오닌 또는 시스테인 잔기가 다른 아미노산 잔기, 구체적으로, 루이신 또는 발린 잔기로 치환된다. 특정 구체예에서, 녹농균(Pseudomonas aeruginosa) 아주린(SEQ ID NO: 1)의 잔기 56 또는 64에 동등한 쿠프레독신 유래된 펩티드의 하나이상의 메티오닌 잔기가 치환된다. 다른 특정 구체예에서, 이러한 분리된 펩티드는 SEQ ID NO: 31 또는 SEQ ID NO: 32를 포함한다.
일부 구체예에서, 분리되고 변형된 쿠프레독신 유래된 펩티드는 디켑토피페라진(diketopiperazine)과 피로글루타민산(pyroglutamic acid) 형성에 더욱 적게 민감하다. 구체적으로, 이러한 분리된 펩티드는 쿠프레독신 유래된 펩티드의 N-말단으로부터 위치 1, 2 또는 3에서 글리신 잔기가 다른 아미노산 잔기로 치환된다. 게다가, 이러한 분리된 펩티드는 쿠프레독신 유래된 펩티드의 N-말단으로부터 위치 3에서 프롤린 잔기가 다른 아미노산 잔기로 치환된다. 더 나아가, 이러한 분리된 펩티드는 쿠프레독신 유래된 펩티드의 N-말단에서 아스파라긴 잔기가 다른 아미노산 잔기로 치환된다.
일부 구체예에서, 분리되고 변형된 쿠프레독신 유래된 펩티드는 라세미화(racemization)에 더욱 적게 민감하다. 구체적으로, 이러한 분리된 펩티드는 쿠프레독신 유래된 펩티드의 하나이상의 아미노산 잔기가 상기 아미노산 잔기의 D-이성질체로 치환된다. 특정 구체예에서, 쿠프레독신 유래된 펩티드의 전체 아미노산 잔기가 이들 아미노산 잔기의 D-이성질체로 치환된다. 다른 특정 구체예에서, 이러한 분리된 펩티드는 SEQ ID NO: 45를 포함한다.
일부 구체예에서, 분리되고 변형된 쿠프레독신 유래된 펩티드는 변성(degradation)에 더욱 적게 민감하다. 구체적으로, 쿠프레독신 유래된 펩티드의 N-말단이 아세틸화된다. 게다가, 쿠프레독신 유래된 펩티드의 C-말단이 아미드화된다. 특정 구체예에서, 분리된 펩티드는 SEQ ID NO: 33이다.
일부 구체예에서, 분리되고 변형된 쿠프레독신 유래된 펩티드는 3차 구조의 안정성이 증가하도록 변형된다. 구체적으로, 이러한 분리된 펩티드는 최소한 하나의 α-나선의 안정성이 증가하도록 변형된다. 일부 구체예에서, 글리신, 프롤린, 세린, 아스파르트산, 알라닌, 트레오닌, 발린, 글루타민, 아스파라긴, 시스테인, 히스티딘, 리신과 아르기닌으로 구성된 군에서 선택되는 쿠프레독신 유래된 펩티드의 최소한 하나의 아미노산 잔기가 루이신, 이소루이신, 페닐알라닌, 글루타민산, 티로신, 트립토판과 메티오닌으로 구성된 군에서 선택되는 아미노산 잔기로 치환된다. 특정 구체예에서, 쿠프레독신 유래된 펩티드의 치환된 잔기가 녹농균(P. aeruginosa) 아주린의 잔기 53-56, 58-64와 68-70에 동등한 잔기 내에 존재한다. 다른 특정 구체예에서, 녹농균(P. aeruginosa) 아주린의 잔기 57에 동등한 잔기에서 글루타민이 트립토판 잔기로 치환되고, 녹농균(P. aeruginosa) 아주린의 잔기 52에 동등한 잔기에서 트레오닌이 트립토판 잔기로 치환되고, 녹농균(P. aeruginosa) 아주린의 잔기 61에 동등한 잔기에서 트레오닌이 트립토판 잔기로 치환되고 및/또는 녹농균(P. aeruginosa) 아주린의 잔기 63에 동등한 잔기에서 글리신이 트립토판 잔기로 치환된다. 다른 특정 구체예에서, 이러한 분리된 펩티드는 SEQ ID NO: 34-44 중에서 하나이다.
다른 구체예에서, 이러한 분리된 펩티드는 쿠프레독신 유래된 펩티드의 2개 이상의 리신 잔기가 i(i+4) 간격(spacing)에서 ε-(3,5-디니트로벤조일)-리신 잔기로 치환된다. 구체적으로, 쿠프레독신 유래된 펩티드의 치환된 잔기가 녹농균(P. aeruginosa) 아주린의 잔기 53-56, 58-64와 68-70에 동등한 잔기 내에 존재한다.
다른 구체예에서, 이러한 분리된 펩티드는 히스티딘-시스테인 또는 히스티딘-히스티딘 잔기 쌍이 i(i+4) 간격에서 쿠프레독신 유래된 펩티드 내로 치환되고, 상기 펩티드는 Cu, Zn, Cd와 Ru로 구성된 군에서 선택되는 최소한 하나의 이온을 더욱 포함한다. 특정 구체예에서, 이러한 분리된 펩티드는 쿠프레독신 유래된 펩티드의 치환된 잔기가 녹농균(P. aeruginosa) 아주린의 잔기 53-56, 58-64와 68-70에 동등한 잔기 내에 존재한다.
다른 구체예에서, 이러한 분리된 펩티드는 쿠프레독신 유래된 펩티드 내에서 고유 아미노산 잔기의 하나이상의 쌍이 고유 아미노산에 상응하는 올레핀-보유 테 터(olefin-bearing tether)를 포함하는 α,α-이중치환된 비-자연 아미노산으로 치환된다. 이러한 분리된 펩티드는 쿠프레독신 유래된 펩티드의 치환된 잔기가 녹농균(P. aeruginosa) 아주린의 잔기 53-56, 58-64와 68-70에 동등한 잔기 내에 존재한다.
일부 구체예에서, 분리되고 변형된 쿠프레독신 유래된 펩티드는 쿠프레독신 유래된 펩티드에 공유 결합된 하나이상의 PEG(폴리에틸렌 글리콜) 분자를 보유한다. 구체적으로, 이러한 분리된 펩티드는 하나이상의 PEG 분자가 쿠프레독신 유래된 펩티드의 하나이상의 시스테인 잔기에 공유 결합된다. 특정 구체예에서, 이러한 분리된 펩티드는 하나이상의 PEG 분자가 녹농균(Pseudomonas aeruginosa) 아주린(SEQ ID NO: 1)의 아미노산 잔기 3, 6과 112로 구성된 군에서 선택되는 잔기에 동등한 하나이상의 시스테인 잔기에 공유 결합된다. 다른 구체예에서, 시스테인 잔기가 쿠프레독신 유래된 펩티드 내로 치환되고, PEG 분자에 공유 결합된다.
다른 구체예에서, 이러한 분리된 펩티드는 하나이상의 PEG 분자가 리신, 시스테인, 히스티딘, 아르기닌, 아스파르트산, 글루타민산, 세린, 트레오닌, 티로신, N-말단 아미노기와 C-말단 카르복실산으로 구성된 군에서 선택되는 하나이상의 부위에서 쿠프레독신 유래된 펩티드에 공유 결합된다. 특정 구체예에서, 이러한 분리된 펩티드는 하나이상의 리신 잔기 또는 C-말단 카르복실산이 PEG 분자에 공유 결합된다. 다른 구체예에서, 리신, 시스테인, 히스티딘, 아르기닌, 아스파르트산, 글루타민산, 세린, 트레오닌과 티로신 잔기로 구성된 군에서 선택되는 하나이상의 잔기가 쿠프레독신 유래된 펩티드 내로 치환되고, PEG 분자에 공유 결합된다. 다른 구체예에서, 하나 이상의 PEG 분자가 쿠프레독신 유래된 펩티드의 하나이상의 아미노기가 공유 결합되거나, 또는 쿠프레독신 유래된 펩티드에 무작위로 공유 결합된다.
쿠프레독신 유래된 펩티드당 PEG 분자의 평균 분자량(average molecular weight)은 대략 200 내지 대략 100,000 달톤(dalton)이다. 이러한 쿠프레독신 유래된 펩티드는 하나이상의 가지형 PEG 분자에 공유 결합되는데, 여기서 가지형 PEG 분자는 대략 50 kDa이다. 이러한 쿠프레독신 유래된 펩티드는 하나이상의 선형 PEG 분자에 공유 결합되는데, 여기서 선형 PEG 분자는 대략 5 kDa이다.
본 발명의 다른 측면은 변형된 쿠프레독신 유래된 펩티드 및 제약학적으로 허용되는 담체를 함유하는 제약학적 조성물이다.
본 발명의 다른 측면은 포유동물의 장애를 치료하는 방법인데, 상기 방법은 변형된 쿠프레독신 유래된 펩티드의 치료 효과량을 포유동물에 투여하는 단계를 포함한다. 특정 구체예에서, 포유동물은 인간이다.
본 발명의 다른 측면은 아미노산 서열 X1SX2AADX3X4X5VVX6DX7X8ASGLDKDYLKPDX9 (SEQ ID NO:48)를 포함하거나, 또는 대안으로, 이런 아미노산 서열로 구성되는 분리된 펩티드인데, 여기서 X1은 L 또는 아세틸화된-L에서 선택되고; X2는 T 또는 W에서 선택되고; X3은 M, L 또는 V에서 선택되고; X4는 Q 또는 W에서 선택되고; X5는 G 또는 A에서 선택되고; X6은 T 또는 W에서 선택되고; X7은 G, T 또는 W에서 선택되 고; X8은 M, L 또는 V에서 선택되고; X9는 D 또는 아미드화된-D에서 선택된다.
본 발명의 다른 측면은 아미노산 서열 아미노산 서열 X1DPKLYDKDLGSAX2X3DX4VVX5X6X7DAAX8SX9 (SEQ ID NO:49)를 포함하거나, 또는 대안으로, 이런 아미노산 서열로 구성되는 분리된 펩티드인데, 여기서 X1은 D 또는 아세틸화된-D에서 선택되고; X2는 M, L 또는 V에서 선택되고; X3은 G, T 또는 W에서 선택되고; X4는 T 또는 W에서 선택되고; X5는 G 또는 A에서 선택되고; X6은 Q 또는 W에서 선택되고; X7은 M, L 또는 V에서 선택되고; X8은 T 또는 W에서 선택되고; X9는 L 또는 아미드화된-L에서 선택된다.
본 발명의 다른 측면은 SEQ ID NO: 50-3506의 서열을 포함하거나, 또는 이런 서열로 구성되는 분리된 펩티드이다.
서열에 관한 간단한 설명:
SEQ ID NO: 1은 wt-녹농균(Pseudomonas aeruginosa)으로부터 아주린의 아미노산 서열이다.
SEQ ID NO: 2는 포르미디움 라미노슘(Phormidium laminosum)으로부터 플라스토시아닌의 아미노산 서열이다.
SEQ ID NO: 3은 티오바실루스 페로옥시단스(Thiobacillus ferrooxidans)로부터 루스티시아닌의 아미노산 서열이다.
SEQ ID NO: 4는 아크로모박터 시클로클라스테스(Achromobacter cycloclastes)로부터 슈도아주린의 아미노산 서열이다.
SEQ ID NO: 5는 슈도모나스 시린가에(Pseudomonas syringae)로부터 아주린의 아미노산 서열이다.
SEQ ID NO: 6은 임균(Neisseria gonorrhoeae)으로부터 Laz의 아미노산 서열이다.
SEQ ID NO: 7은 수막염균(Neisseria meningitides)으로부터 Laz의 아미노산 서열이다.
SEQ ID NO: 8은 장염 비브리오(Vibrio parahaemolyticus)로부터 아주린의 아미노산 서열이다.
SEQ ID NO: 9는 보르데텔라 브론키셉티카(Bordetella bronchiseptica)로부터 아주린의 아미노산 서열이다.
SEQ ID NO: 10은 클로로플렉서스 아우란티아쿠스(Chloroflexus aurantiacus)로부터 아우라시아닌 A의 아미노산 서열이다.
SEQ ID NO: 11은 클로로플렉서스 아우란티아쿠스(Chloroflexus aurantiacus)로부터 아우라시아닌 B의 아미노산 서열이다.
SEQ ID NO: 12는 백일해(Bordetella pertussis)로부터 아주린의 아미노산 서열이다.
SEQ ID NO: 13은 녹농균(Pseudomonas aeruginosa)으로부터 wt-아주린의 50-77 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 14는 녹농균(Pseudomonas aeruginosa)으로부터 wt-아주린의 50-67 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 15는 녹농균(Pseudomonas aeruginosa)으로부터 wt-아주린의 36-128 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 16은 녹농균(Pseudomonas aeruginosa)으로부터 wt-아주린의 36-89 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 17은 녹농균(Pseudomonas aeruginosa)으로부터 wt-아주린의 36-77 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 18은 녹농균(Pseudomonas aeruginosa)으로부터 wt-아주린의 36-50 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 19는 녹농균(Pseudomonas aeruginosa)으로부터 wt-아주린의 50-66 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 20은 녹농균(Pseudomonas aeruginosa)으로부터 wt-아주린의 67-77 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 21은 클로로플렉서스 아우란티아쿠스(Chloroflexus aurantiacus)의 아우라시아닌 B의 57-89 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 22는 백일해(Bordetella pertussis)로부터 아주린의 50-77 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 23은 수막염균(Neisseria meningitidis)으로부터 Laz 단백질의 89-115 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 24는 녹농균(Pseudomonas aeruginosa)으로부터 아주린의 53-70 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 25는 녹농균(Pseudomonas aeruginosa)으로부터 아주린의 53-64 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 26은 녹농균(Pseudomonas aeruginosa)으로부터 아주린의 51-77 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 27은 슈도모나스 시린가에(Pseudomonas syringae)로부터 아주린의 51-77 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 28은 장염 비브리오(Vibrio parahaemolyticus)로부터 아주린의 52-78 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 29는 보르데텔라 브론키셉티카(Bordetella bronchiseptica)로부터 아주린의 51-77 아미노산 단편의 아미노산 서열이다.
SEQ ID NO: 30은 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 31은 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 32는 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 33은 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 34는 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 35는 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 36은 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 37은 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 38은 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 39는 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 40은 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 41은 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 42는 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 43은 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 44는 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 45는 녹농균(Pseudomonas aeruginosa) 아주린의 50-77 아미노산 영역의 변이체 형태에 대한 인공 서열이다.
SEQ ID NO: 46은 아주린으로부터 보존된 아미노산 서열인데, 여기서 D는 아스파르트산, G는 글리신, Y는 티로신, K는 리신, X는 임의의 아미노산이다.
SEQ ID NO: 47은 아주린으로부터 보존된 아미노산 서열인데, 여기서 D는 아스파르트산, G는 글리신, Y는 티로신, K는 리신, X는 임의의 아미노산이다.
SEQ ID NO: 48은 녹농균(Pseudomonas aeruginosa)의 아주린 50-77에 변형의 인공 서열이다.
SEQ ID NO: 49는 녹농균(Pseudomonas aeruginosa)의 아주린 50-77의 D-이성질체에 변형의 인공 서열이다.
SEQ ID NO: 50-3506은 변형된 쿠프레독신 유래된 펩티드의 인공 서열이다.
도 1에서는 표지된 p18이 주입된 생쥐의 전신 스캔(whole scan)의 영상을 도시한다. IRDye® 표지된 p18(125 ㎍)은 정맥내 주입되고, 무흉선 생쥐는 Odyssey® Infrared Imaging System을 이용하여, 종양과 장기 내에서 표지된 염료의 탐지를 위하여 지정된 시점에서 스캔되었다.
도 2에서는 표지된 p18이 주입된 생쥐의 전신과 장기 스캔으로부터 영상을 도시한다. i.v. 주입후 120 시간(희생 직전)에 125 ㎍ IRDye® 표지된 p18. 절제된 장기는 스캔되고 오른쪽에 도시된다. p18 신호는 신장과 Mel-2 종양으로부터 관찰되었다.
도 3. Mel-2 피하 종양은 Mel-2 세포가 주입된 이후 3주 시점에, 125 ㎍ IRDye® 표지된 p18이 i.v. 투여되고, 48시간 후에 Odyssey® 적외선 스캔(infrared scan)이 수행되었다. 800 ㎚ 채널에서 기록된 영상은 IRDye®로부터 특이적인 p18 신호를 나타내고, 700 ㎚ 채널에서 기록된 영상은 배경(background)을 나타낸다. p18 신호는 신장과 Mel-2 종양으로부터 관찰되었다.
정의
본 명세서에서, "세포"는 "단일 세포"로서 구체적으로 명시되지 않는 경우에, 상기 용어의 단수와 복수를 모두 포괄한다.
본 명세서에서, "폴리펩티드", "펩티드"와 "단백질"은 동일한 의미로서 이용되고, 아미노산 잔기의 중합체를 지시한다. 상기 용어는 하나이상의 아미노산 잔기가 상응하는 자연 발생 아미노산의 인공적인 화학 유사체인 아미노산 중합체에 적용된다. 상기 용어는 자연 발생 아미노산 중합체에도 적용된다. "폴리펩티드", "펩티드"와 "단백질"은 당화(glycosylation), 지질 부착(lipid attachment), 황화(sulfation), 글루타민산(glutamic acid) 잔기의 감마-카르복실화(gamma-carboxylation), 하이드록실화(hydroxylation), ADP-리보실화(ribosylation)가 포함되지만 이들에 국한되지 않는 변형 역시 포함한다. 폴리펩티드가 항상 완전하게 선형인 것은 아니다. 가령, 폴리펩티드는 유비퀴틴화(ubiquitination)의 결과로써 가지화되고, 일반적으로, 자연적인 처리 현상(natural processing event)과 자연적으로 발생하지 않고 인간 조작에 의해 유발되는 현상을 비롯한 번역후 현상(post-translation event)의 결과로써 환형(분지화되거나 가지화되지 않음)이다. 환형 폴리펩티드, 가지화된 폴리펩티드와 가지화된 환형 폴리펩티드는 비-번역 자연 과정 및 전적으로 합성 방법에 의해 합성될 수도 있다. 합성 펩티드는 세포 성분의 보조 없이 만들어진 펩티드이다. 펩티드를 만드는 합성 방법은 당분야에 널리 공지되어 있고, 상업적으로 가용하다. 더 나아가, 본 발명에서는 본 발명의 단백질의 메티오닌-보유와 메티오닌-없는 아미노 말단 변이체의 이용을 고려한다.
본 명세서에서, "장애"는 생존 동물 또는 이의 일부분의 정상 상태의 손상을 구성하고, 신체 기능의 수행을 교란시키거나 변형하는, 정상으로부터 해부학적, 생리학적 이탈을 포괄한다.
본 명세서에서, "세포 성장의 저해"는 세포 분열(cell division) 및/또는 세포 팽창(cell expansion)의 지연 또는 중지를 의미한다. 상기 용어는 세포 발달의 저해 또는 세포 사멸의 증가 역시 의미한다.
본 명세서에서, "고통받는"은 현재 장애의 증상을 나타내고, 관찰가능 증상이 없음에도 장애를 앓거나, 장애로부터 회복 중이거나, 또는 장애로부터 회복된 것을 포괄한다.
본 명세서에서, "치료"는 치료하려는 장애 또는 이러한 장애와 연관된 증상의 진행 또는 심각도를 예방, 저하, 중단 또는 반전시키는 것을 포괄한다. 따라서, "치료"에는 적절한 의학적, 치료적 및/또는 예방적 투여가 포함된다.
"치료 효과량"은 치료되는 개체에서 특정한 장애의 발생을 예방, 저하, 중단 또는 반전시키고, 또는 특정한 장애 또는 이러한 장애의 기존 증상을 부분적으로 또는 완전하게 완화시키는데 효과적인 양이다. 치료 효과량의 결정은 당업자의 능력 범위 내에 속한다.
본 명세서에서, "약리 활성"은 생물계(biological system)에 대한 약물 또는 다른 화학물질의 효과를 의미한다. 화학물질의 효과는 유익(치료)하거나, 또는 유해(독성)하다. 순수한 화학물질 또는 혼합물은 자연 기원(식물, 동물, 또는 광물)이거나, 또는 합성 화합물이다.
본 명세서에서, "전악성(premalignant)"은 전암성(precancerous), 또는 비정상 세포가 통제 없이 분화되기 이전을 의미한다.
본 명세서에서, "약동학적 특성(pharmacokinetic property)"은 생물체 또는 호스트 내에서 활성제 또는 약물의 성향(disposition)을 설명하는 파라미터를 지칭한다. 대표적인 약동학적 특성에는 혈장 반감기(plasma half-life), 간 일차-패스 물질대사(hepatic first-pass metabolism), 분포 체적(volume of distribution), 혈액 혈청 단백질, 예를 들면, 알부민(albumin) 결합의 정도 등이 포함된다.
본 명세서에서, "혈장 반감기"는 생리 과정, 예를 들면, 생체물질대사(biometabolism), 배출(excretion) 등을 통하여, 투여된 약물의 절반이 환자의 혈장으로부터 제거되는 시간을 지칭한다.
본 명세서에서, "분포 체적"은 생물체의 다양한 구획(compartment), 예를 들면, 세포내와 세포외 공간, 조직과 장기 등을 통한 약물의 분포와 체류 정도를 지칭한다. 이러한 인자는 약물이 분포된 신체의 추정된 체적인 "겉보기 분포 체적(apparent volume of distribution)" 또는 Vd로 표시된다. 큰 Vd는 약물이 전신에서 더욱 폭넓게 분포한다는 것을 암시하고 더욱 긴 반감기와 연관되는데, 그 이유는 더욱 적은 분량의 약물이 혈장 내에 존재하고 제거 지점(elimination point), 신장과 간으로 전달될 것이기 때문이다.
본 명세서에서, "혈액 혈청 결합의 정도"는 혈액 혈청 단백질, 예를 들면, 알부민에 의해 결합되는 약물의 성향을 지칭한다.
본 명세서에서, "효능"은 의도된 목적에 대한 특정 활성제의 효능, 다시 말하면, 소요의 약리학적 효과를 유도하는 일정한 활성제의 능력을 지칭한다.
본 명세서에서, "고유 활성(specific activity)"은 효소 ㎎(milligram)당, 일정한 조건 하에 일정한 시간에서 효소에 의해 형성되는 산물의 양을 지칭한다. 고유 활성은 효소의 부피로 나눗셈된 반응 체적(volume of reaction)으로 곱셈된 반응 속도에 상당한다. 수송 펩티드(transport peptide)의 경우에, 고유 활성은 수송 펩티드 또는 수송 펩티드-화물 복합체 ㎎(milligram)당, 일정한 조건 하에 일정한 시간에서 세포 내로 내재화되는 수송 펩티드 또는 수송 펩티드-화물 복합체의 양이다.
본 명세서에서, 본 발명의 단백질 또는 다른 세포 산물을 수식하는데 이용되는"실질적으로 순수한"은 예로써, 다른 단백질 및/또는 활성 저해 화합물이 실질적으로 존재하지 않거나 섞이지 않은 형태로 성장 배지 또는 세포 내용물로부터 분리된 단백질을 지시한다. "실질적으로 순수한"은 분리된 분획물의 건물 중량(dry weight)당 최소한 75%의 인자(factor), 또는 최소한 "75% 실질적으로 순수한" 인자를 지시한다. 더욱 적절하게는, "실질적으로 순수한"은 활성 화합물의 건물 중량당 최소한 85%의 화합물, 또는 최소한 "85% 실질적으로 순수한" 화합물을 지시한다. 가장 적절하게는, "실질적으로 순수한"은 활성 화합물의 건물 중량당 최소한 95%의 화합물, 또는 최소한"95% 실질적으로 순수한" 화합물을 지시한다. "실질적으로 순수한"은 합성된 단백질 또는 화합물을 수식하는 데에도 이용될 수 있는데, 여기서 예로써, 이러한 합성 단백질은 합성 반응의 반응물과 부산물로부터 분리된다.
본 명세서에서, 본 발명의 펩티드 또는 단백질과 관련하여 "제약학적 등급(pharmaceutical grade)"은 합성 반응물과 부산물을 비롯한, 자연 상태에서 통상적으로 수반되는 성분으로부터 실질적으로 또는 본질적으로 분리되고, 약제로서 이의 활용을 제약하는 성분으로부터 실질적으로 또는 본질적으로 분리된 펩티드 또는 화합물을 지시한다. 가령, "제약학적 등급" 펩티드는 임의의 암종(carcinogen)으로부터 분리된다. 일부 사례에서, "제약학적 등급"은 조성물을 환자에 대한 정맥내 투여에 부적합하도록 만드는 임의의 물질로부터 실질적으로 또는 본질적으로 분리된 펩티드 또는 화합물을 명시하기 위하여, 의도된 투여 방법에 의해 수식된다(가령, "정맥내 제약학적 등급(intravenous pharmaceutical grade)"). 가령, "정맥내 제약학적 등급" 펩티드는 SDS와 같은 세정제(detergent) 및 아지드(azide)와 같은 항균제(anti-bacterial agent)로부터 분리된다.
"분리된", "정제된" 또는 "생물학적으로 순수한"은 자연 상태에서 통상적으로 수반되는 성분이 실질적으로 또는 본질적으로 존재하지 않는 물질을 지시한다. 따라서, 본 발명에 따른 분리된 펩티드는 가급적, in situ 환경에서 이들 펩티드와 통상적으로 연관되는 물질을 포함하지 않는다. "분리된" 영역은 이러한 영역이 유래되는 폴리펩티드의 전체 서열을 보유하지 않는 영역을 의미한다. "분리된" 핵산, 단백질, 또는 이의 개별 단편은 뉴클레오티드 염기서열분석(nucleotide sequencing), 제한 절단(restriction digestion), 특정 부위 돌연변이유발(site-directed mutagenesis), 핵산 단편에 대한 발현 벡터 내로 서브클로닝(subcloning) 및 실질적으로 순수한 양으로 단백질 또는 단백질 단편의 획득이 포함되지만 이들에 국한되지 않는, 당업자에 의한 조작으로 생체내 환경으로부터 실질적으로 이전된다.
본 명세서에서, 펩티드를 지칭하는데 이용되는 "야생형"은 상기 펩티드가 자연 발생 펩티드와 동일한 서열을 갖는다는 것을 의미한다.
본 명세서에서, 펩티드와 관련하여 "변이체"는 야생형 폴리펩티드와 비교하여, 아미노산이 치환된, 결실된, 또는 삽입된 아미노산 서열 변이체를 지칭한다. 변이체는 야생형 펩티드의 절두(truncation)일 수 있다. "결실(deletion)"은 야생형 단백질 내에서 하나이상의 아미노산의 제거이고, "절두"는 야생형 단백질의 하나이상의 말단으로부터 하나이상의 아미노산의 제거이다. 따라서, 변이체 펩티드는 이러한 폴리펩티드를 인코딩하는 유전자의 조작으로 만들어진다. 변이체는 폴리펩티드의 근본적인 약리 활성의 최소한 일부에는 변화 없이 기본적인 조성이나 특성을 변화시킴으로써 만들어진다. 가령, 녹농균(Pseudomonas aeruginosa) 통과 펩티드(transit peptide)의 "변이체"는 암 세포를 침입하는 능력을 유지하는 돌연변이된 녹농균(Pseudomonas aeruginosa) 통과 펩티드일 수 있다. 일부 사례에서, 변이체 펩티드는 비-자연 아미노산, 예를 들면, ε-(3,5-디니트로벤조일)-Lys 잔기로 합성된다(Ghadiri & Fernholz, J. Am. Chem. Soc., 112:9633-9635 (1990)). 일부 구체예에서, 변이체는 야생형 펩티드 또는 이의 일부분과 비교하여 20개, 19개, 18개, 17개 또는 16개 이하의 아미노산이 치환, 결실 또는 삽입된다. 일부 구체예에서, 변이체는 야생형 펩티드 또는 이의 일부분과 비교하여 15개, 14개, 13개, 12개 또는 11개 이하의 아미노산이 치환, 결실 또는 삽입된다. 일부 구체예에서, 변이체는 야생형 펩티드 또는 이의 일부분과 비교하여 10개, 9개, 8개 또는 7개 이하의 아미노산이 치환, 결실 또는 삽입된다. 일부 구체예에서, 변이체는 야생형 펩티드 또는 이의 일부분과 비교하여 6개 이하의 아미노산이 치환, 결실 또는 삽입된다. 일부 구체예에서, 변이체는 야생형 펩티드 또는 이의 일부분과 비교하여 5개 또는 4개 이하의 아미노산이 치환, 결실 또는 삽입된다. 일부 구체예에서, 변이체는 야생형 펩티드 또는 이의 일부분과 비교하여 3개, 2개 또는 1개 이하의 아미노산이 치환, 결실 또는 삽입된다.
본 명세서에서, "아미노산"은 임의의 자연-발생 또는 비-자연 발생 또는 합성 아미노산 잔기를 포함하는 아미노산 모이어티(moiety), 다시 말하면, 1개, 2개, 3개 또는 그 이상의 탄소 원자, 전형적으로, 1개의 (α) 탄소 원자에 의해 직접적으로 연결된 최소한 하나의 카르복실 잔기와 최소한 하나의 아미노 잔기를 포함하는 임의의 모이어티를 의미한다. 아미노산은 아미노산의 L-이성질체 또는 D-이성질체일 수 있다.
본 명세서에서, 펩티드와 관련하여 "유도체"는 표적 펩티드로부터 유래된 펩티드를 지칭한다. 유도(derivation)는 펩티드가 근본적인 약리 활성 중에서 일부를 여전히 유지하도록 하는 상기 펩티드의 화학적 변형을 포함한다. 가령, 녹농균(Pseudomonas aeruginosa) 통과 펩티드(transit peptide)의 "유도체"는 암 세포를 침입하는 능력을 유지하는 화학적으로 변형된 녹농균(Pseudomonas aeruginosa) 통과 펩티드일 수 있다. 목적하는 화학적 변형에는 펩티드의 아미드화(amidation), 아세틸화(acetylation), 황화(sulfation), 폴리에틸렌 글리콜(PEG) 변형, 인산화(phosphorylation), 당화(glycosylation)가 포함되지만 이들에 국한되지 않는다. 이에 더하여, 유도체 펩티드는 화학적 화합물, 예를 들면, 다른 펩티드, 약제 분자 또는 다른 치료제 또는 조제약, 또는 탐지가능 프로브에 폴리펩티드의 융합체(fusion)일 수도 있다.
본 명세서에서, "아미노산 서열 동일성 비율(%)"은 두 서열을 정렬하는 경우에 후보 서열에서 아미노산 잔기와 일치하는 폴리펩티드에서 아미노산 잔기의 비율로서 정의된다. 아미노산 동일성 비율(%)을 결정하기 위하여, 서열은 정렬하고, 필요한 경우, 최대 서열 동일성 비율(％)을 확보하기 위하여 갭(gap)을 도입한다; 보존성 치환은 서열 동일성의 일부로서 간주되지 않는다. 동일성 비율(％)을 측정하기 위한 아미노산 서열 정렬 절차는 당업자에게 공지되어 있다. 공개적으로 가용한 컴퓨터 소프트웨어, 예를 들면, BLAST, BLAST2, ALIGN 또는 Megalign(DNASTAR) 소프트웨어가 펩티드 서열을 정렬하는데 이용된다. 특정한 구체예에서, Blastp(National Center for Biotechnology Information, Bethesda MD로부터 입수가능)는 long complexity filter, expect 10, word size 3, existence 11, extension 1의 디폴트 파라미터에서 이용된다.
아미노산 서열을 정렬하는 경우에, 일정한 아미노산 서열 B에 대한 일정한 아미노산 서열 A(또는, 일정한 아미노산 서열 B에 대한 특정의 아미노산 서열 동일성(％)을 갖거나 포함하는 일정한 아미노산 서열 A)의 아미노산 서열 동일성 비율(%)은 아래와 같이 산정될 수 있다:
아미노산 서열 동일성 비율(%) = X/Y * 100
여기서, X는 서열 정렬 프로그램 또는 알고리즘 정렬에 의해 A와 B의 동일한 정합(match)으로 기록되는 아미노산 잔기의 수이고,
Y는 B에서 아미노산 잔기의 총수이다.
아미노산 서열 A의 길이가 아미노산 서열 B의 길이와 동등하지 않는 경우, B에 대한 A의 아미노산 서열 동일성 비율(％)은 A에 대한 B의 아미노산 서열 동일성 비율(％)과 일치하지 않을 것이다. 더욱 짧은 서열에 더욱 긴 서열을 비교하는 경우에, 더욱 짧은 서열이 "B" 서열이 될 것이다. 가령, 상응하는 야생형 폴리펩티드에 절두된 폴리펩티드를 비교하는 경우에, 절두된 펩티드가 "B" 서열이 될 것이다.
총론
본 발명은 쿠프레독신의 하나이상의 약리 활성을 유지하면서, 향상된 약동학적 특성, 예를 들면, 향상된 안정성, 고유 활성, 혈류에서 반감기 및/또는 감소된 면역원성을 나타내는 쿠프레독신 유래된 펩티드에 관계한다. 부가적으로, 본 발명은 변형된 쿠프레독신 유래된 펩티드로부터 유래된 화합물에 관계하는데, 이들 역시 쿠프레독신의 하나이상의 약리 활성을 유지하면서 향상된 약동학적 특성을 나타낸다. 최종적으로, 본 발명은 포유동물 환자가 겪는 다양한 장애를 치료 및/또는 진단하고, 포유동물 환자가 겪는 다양한 장애를 조사하기 위하여, 변형된 쿠프레독신 유래된 펩티드 및 이들로부터 만들어진 화합물을 이용하는 방법에 간계한다.
조성물
본 발명은 향상된 약동학적 특성을 나타내는 쿠프레독신 유래된 펩티드의 변형 펩티드에 관계한다. 일부 구체예에서, 이들 변형된 쿠프레독신 유래된 펩티드는 쿠프레독신의 최소한 하나의 약리 활성을 유지한다. 일부 구체예에서, 변형된 쿠프레독신 유래된 펩티드는 분리되거나, 실질적으로 순수하거나, 또는 제약학적 등급이다. 특정 구체예에서, 변형된 쿠프레독신 유래된 펩티드는 정맥내 제약학적 등급니다.
쿠프레독신, 특히, 녹농균(Pseudomonas aeruginosa)으로부터 아주린은 포유동물 환자를 치료 및/또는 진단하고, 포유동물 환자가 겪는 장애를 조사하는데 유용한 여러 약리 활성을 갖는 것으로 알려져 있다. 가령, 다수의 쿠프레독신 단백질, 예를 들면, 녹농균(Pseudomonas aeruginosa) 아주린은 많은 유형의 포유동물 암 세포를 특이적으로 침입하고 사멸시키는 능력을 갖는다. Yamada et al., Cell. Biol. 7:1418-1431 (2005); Hiraoka et al., PNAS 101:6427-6432 (2004); Hiraoka et al., Biochem. Biophys. Res. Comm. 338:1284-1290 (2005); U.S. Patent Application No. 11/244,105(2005년 10월 6일 제출됨); U.S. Patent Application No. 10/720,603(2003년 11월 24일 제출됨); U.S. Patent Application No. 10/047,710(2002년 1월 15일 제출됨); U.S. Patent Application No. 11/485,252(2006년 7월 13일 제출됨). 녹농균(P. aeruginosa)으로부터 아주린은 또한, 바이러스 또는 세균 감염, 더욱 구체적으로, 말초혈 단핵 세포(peripheral blood mononuclear cell)에서 HIV-1 감염의 성장을 저해하고, 말라리아-감염된 포유동물 적혈구 세포의 기생충혈증을 저해하는 것으로 알려져 있다. Chaudhari et al., Cell Cycle. 5:1642-1648 (2006); U.S. Patent Application No. 11/436,591(2006년 5월 19일 제출됨); U.S. Patent Application No. 11/436,590(2006년 5월 19일 제출됨). 녹농균(P. aeruginosa)으로부터 아주린은 또한, 다양한 포유동물 세포와 조직에서 에프린 신호전달 체계(ephrin signaling system)를 간섭하는 것으로 알려져 있다. U.S. Patent Application No. 11/436,592(2006년 5월 19일 제출됨). 게다가, 녹농균(P. aeruginosa) 아주린으로부터 유래된 펩티드는 포유동물 세포, 구체적으로, 인간 배꼽 혈관 내피 세포(umbilical vascular endothelium cell, HUVEC)에서 혈관신생을 저해하는 것으로 알려져 있다. U.S. Patent Application No. 11/488,693(2006년 7월 19일 제출됨). 일부 구체예에서, 본 발명의 변형된 쿠프레독신 유래된 펩티드는 그들이 유래된 쿠프레독신의 최소한 하나의 약리 활성을 유지한다. 쿠프레독신의 약리 활성은 쿠프레독신의 임의의 유용한 활성일 수 있다. 목적하는 특정 약리 활성에는 포유동물 암 세포로 특이적인 침입 능력, 비-암성 포유동물 세포로 침입 불능, 전-악성 포유동물 세포로 침입 능력, 포유동물 암 세포 사멸 능력, 전-악성 포유동물 세포 사멸 능력, 바이러스 또는 세균 감염의 성장 저해 능력, 말초혈 단핵 세포에서 HIV-1 감염 저해 능력, 말라리아-감염된 적혈구 세포의 기생충혈증 저해 능력, 포유동물 세포, 구체적으로, HUVEC에서 혈관신생 저해 능력이 포함되지만 이들에 국한되지 않는다. 펩티드의 약리 활성의 양을 측정하는 방법은 앞서 언급된 출원과 간행물에서 제공된다.
쿠프레독신 유래된 펩티드는 임의의 변형된 쿠프레독신 유래된 펩티드일 수 있다. 일부 구체예에서, 쿠프레독신 유래된 펩티드는 쿠프레독신의 최소한 하나의 약리 활성을 유지한다. 일부 구체예에서, 쿠프레독신에는 아주린, 플라스토시아닌, 루스티시아닌, 슈도아주린, 아우라시아닌, 아주린-유사 단백질이 포함되지만 이들에 국한되지 않는다.
쿠프레독신 유래된 펩티드는 녹농균(Pseudomonas aeruginosa), 포르미디움 라미노슘(Phormidium laminosum), 티오바실루스 페로옥시단스(Thiobacillus ferrooxidans), 아크로모박터 시클로클라스테스(Achromobacter cycloclastes), 슈도모나스 시린가에(Pseudomonas syringae), 수막염균(Neisseria meningitidis), 장염 비브리오(Vibrio parahaemolyticus), 보르데텔라 브론키셉티카(Bordetella bronchiseptica), 백일해(Bordetella pertussis), 클로로플렉서스 아우란티아쿠스(Chloroflexus aurantiacus), 임균(Neisseria gonorrhoeae)이 포함되지만 이들에 국한되지 않는 임의의 생물체로부터 유래될 수 있다. 일부 구체예에서, 쿠프레독신은 아주린, 특히, 녹농균(Pseudomonas aeruginosa), 슈도모나스 시린가에(Pseudomonas syringae). 임균(Neisseria gonorrhoeae), 장염 비브리오(Vibrio parahaemolyticus), 보르데텔라 브론키셉티카(Bordetella bronchiseptica)가 포함되지만 이들에 국한되지 않는 생물체로부터 유래된 아주린이다.
쿠프레독신 유래된 펩티드는 쿠프레독신의 임의의 변이체, 유도체 또는 구조적 등가물일 수 있다. 쿠프레독신 유래된 펩티드는 또한, 당분야에 공지된 및/또는 이전 출원, 예를 들면, U.S. Patent Application No. 11/244,105(2005년 10월 6일 제출됨); U.S. Patent Application No. 10/720,603(2003년 11월 24일 제출됨); U.S. Patent Application No. 10/047,710(2002년 1월 15일 제출됨); U.S. Patent Application No. 11/485,252(2006년 7월 13일 제출됨); U.S. Patent Application No. 11/436,591(2006년 5월 19일 제출됨); U.S. Patent Application No. 11/436,590(2006년 5월 19일 제출됨); U.S. Patent Application No. 11/436,592(2006년 5월 19일 제출됨); U.S. Patent Application No. 11/488,693(2006년 7월 19일 제출됨)에서 기술된 임의의 쿠프레독신 펩티드일 수도 있다. 이들 모든 출원은 본 명세서에서 참조로서 편입된다. 일부 구체예에서, 펩티드는 분리된다. 일부 구체예에서, 펩티드는 실질적으로 순수하거나, 또는 제약학적 등급이다. 다른 구체예에서, 펩티드는 상기 펩티드를 함유하거나, 또는 상기 펩티드로 본질적으로 구성되는 조성물 내에 존재한다. 다른 특정 구체예에서, 펩티드는 포유동물, 더욱 구체적으로, 인간에서 면역 반응을 발생시키지 않는다. 쿠프레독신 유래된 펩티드는 야생형 쿠프레독신과 비교하여 아미노산이 치환된, 결실된, 또는 삽입된 아미노산 서열 변이체이다. 이들 변이체는 야생형 쿠프레독신의 절두일 수도 있다. 쿠프레독신 유래된 펩티드는 전장 이하의 야생형 폴리펩티드인 쿠프레독신의 한 영역을 포함한다. 일부 구체예에서, 쿠프레독신 유래된 펩티드는 절두된 쿠프레독신의 10개 이상의 잔기, 15개 이상의 잔기, 또는 20개 이상의 잔기를 포함한다. 일부 구체예에서, 쿠프레독신 유래된 펩티드는 절두된 쿠프레독신의 100개 이하의 잔기, 50개 이하의 잔기, 40개 이하의 잔기, 30개 이하의 잔기 또는 20개 이하의 잔기를 포함한다. 일부 구체예에서, 쿠프레독신은 쿠프레독신 유래된 펩티드, 더욱 구체적으로, SEQ ID NO: 1-12에 최소한 70% 아미노산 서열 동일성, 최소한 80% 아미노산 서열 동일성, 최소한 90% 아미노산 서열 동일성, 최소한 95% 아미노산 서열 동일성 또는 최소한 99% 아미노산 서열 동일성을 갖는다.
특정한 구체예에서, 쿠프레독신 유래된 변이체는 녹농균(P. aeruginosa) 아주린 잔기 50-77, 아주린 잔기 50-67, 또는 아주린 잔기 36-88을 포함한다. 다른 구체예에서, 쿠프레독신의 변이체는 녹농균(P. aeruginosa) 아주린 잔기 50-77, 아주린 잔기 50-67, 또는 아주린 잔기 36-88로 구성된다. 다른 특정한 구체예에서, 쿠프레독신의 변이체는 아주린 이외의 쿠프레독신의 동등한 잔기로 구성된다. 다른 쿠프레독신의 동등한 잔기를 결정하기 위하여, 표적 쿠프레독신 아미노산 서열은 BLAST, BLAST2, ALIGN2 또는 Megalign(DNASTAR)을 이용하여 녹농균(P. aeruginosa) 아주린 서열, 녹농균(P. aeruginosa) 아주린 아미노산 서열에서 발견되는 관련된 잔기 및 표적 쿠프레독신 서열에서 발견되는 동등한 잔기에 정렬되고, 따라서, 등가의 펩티드가 설계된다.
본 발명의 한 구체예에서, 쿠프레독신 유래된 펩티드는 클로로플렉서스 아우란티아쿠스(Chloroflexus aurantiacus)(SEQ ID NO: 21)의 아우라시아닌 B의 아미노산 57 내지 89를 최소한 포함한다. 본 발명의 다른 구체예에서, 쿠프레독신 유래된 펩티드는 슈도모나스 시린가에(Pseudomonas syringae) 아주린의 아미노산 51-77(SEQ ID NO: 27)을 최소한 포함한다. 본 발명의 다른 구체예에서, 쿠프레독신 변이체는 수막염균(Neisseria meningitidis) Laz의 아미노산 89-115(SEQ ID NO: 23)를 최소한 포함한다. 본 발명의 다른 구체예에서, 쿠프레독신 유래된 펩티드는 장염 비브리오(Vibrio parahaemolyticus) 아주린의 아미노산 52-78(SEQ ID NO: 28)을 최소한 포함한다. 본 발명의 다른 구체예에서, 쿠프레독신 유래된 펩티드는 보르데텔라 브론키셉티카(Bordetella bronchiseptica) 아주린의 아미노산 51-77(SEQ ID NO: 29)을 최소한 포함한다.
쿠프레독신 유래된 펩티드에는 자연적으로 발생하지 않는 합성 아미노산으로 만들어진 펩티드 역시 포함된다. 가령, 비-자연 발생 아미노산은 혈류(bloodstream) 내에서 조성물의 반감기(half-life)를 연장하거나 최적화하기 위하여 변이체 펩티드 내로 편입된다. 이런 변이체에는 D,L-펩티드(부분입체이성질체(diastereomer))(가령, Futaki et al., J. Biol. Chem. 276(8):5836-40(2001); Papo et al., Cancer Res. 64(16):5779-86(2004); Miller et al, Biochem. Pharmacol. 36(1):169-76, (1987)), 특수한 아미노산을 보유하는 펩티드(가령, Lee et al., J. Pept. Res. 63(2):69-84(2004)), 탄화수소 스테이플링(hydrocarbon stapling)이 후행하는 올레핀-보유 비-자연 아미노산(가령, Schafmeister et al., J. Am. Chem. Soc. 122:5891-5892(2000); Walenski et al., Science 305:1466-1470(2004)), ε-(3,5-디니트로벤조일)-Lys 잔기를 포함하는 펩티드가 포함되지만 이들에 국한되지 않는다.
다른 구체예에서, 쿠프레독신 유래된 펩티드는 쿠프레독신의 유도체이다. 쿠프레독신의 유도체는 펩티드가 근본적인 약리 활성 중에서 일부를 여전히 유지하도록 하는 상기 펩티드의 화학적 변형(chemical modification)이다. 가령, 아주린의 "유도체"는 포유동물 암 세포의 성장을 저해하는 능력을 유지하는 화학적으로 변형된 아주린일 수 있다. 목적하는 화학적 변형에는 펩티드의 탄화수소 스테이플링, 아미드화(amidation), 아세틸화(acetylation), 황화(sulfation), 폴리에틸렌 글리콜(PEG) 변형, 인산화(phosphorylation), 당화(glycosylation)가 포함되지만 이들에 국한되지 않는다. 이에 더하여, 유도체 펩티드는 화학적 화합물, 예를 들면, 다른 펩티드, 약제 분자 또는 다른 치료제 또는 조제약, 또는 탐지가능 프로브에 쿠프레독신, 또는 이의 변이체, 유도체 또는 구조적 등가물의 융합체(fusion)일 수도 있다. 목적 유도체는 예로써, 원형화된 펩티드(가령, Monk et al., BioDrugs 19(4):261-78,(2005); DeFreest et al., J. Pept. Res.63(5):409-19(2004)), N-과 C-말단 변형(가령, Labrie et al., Clin. Invest. Med. 13(5):275-8,(1990)), 탄화수소 스테이플링(hydrocarbon stapling)이 후행하는 올레핀-보유 비-자연 아미노산의 통합(가령, Schafmeister et al., J. Am. Chem. Soc. 122:5891-5892(2000); Walenski et al., Science 305:1466-1470(2004))이 포함되지만 이들에 국한되지 않는 당업자에게 널리 공지된 여러 방법에 의해, 혈류 내에서 본 발명의 펩티드와 조성물의 반감기가 연장되거나 최적화될 수 있는 화학적 변형을 보유한다.
다른 구체예에서, 펩티드는 쿠프레독신의 구조적 등가물 또는 쿠프레독신의 절두이다. 쿠프레독신과 다른 단백질 사이에 현저한 구조적 상동성을 결정하는 연구의 실례에는 Toth et al., Developmental Cell 1:82-92(2001)가 포함된다. 구체적으로, 쿠프레독신과 구조적 등가물 사이에 현저한 구조적 상동성은 VAST 알고리즘을 이용함으로써 결정된다(Gibrat et al., Curr Opin Struct Biol 6:377-385(1996); Madej et al., Proteins 23:356-3690(1995)). 특정 구체예에서, 구조적 등가물에 대한 쿠프레독신의 구조적 비교(structural comparison)로부터 VAST p 값은 대략 10-3 이하, 대략 10-5 이하, 또는 대략 10-7 이하이다. 다른 구체예에서, 쿠프레독신과 구조적 등가물 사이에 현저한 구조적 상동성은 DALI 알고리즘을 이용함으로써 결정된다(Holm & Sander, J. Mol. Biol. 233:123-138 (1993)). 특정한 구체예에서, 쌍별 구조적 비교(pairwise structural comparison)에 대한 DALI Z 스코어는 최소한 3.5, 최소한 7.0, 또는 최소한 10.0이다.
목적하는 하나의 특이적인 쿠프레독신 유래된 펩티드는 화물 화합물과 쿠프레독신의 침입 도메인(entry domain)의 융합체이다. 일부 구체예에서, 쿠프레독신 유래된 펩티드는 포유동물 암 세포 내로 특이적으로 침입하고, 따라서 화물 화합물을 세포, 특히, 암 세포 내로 전달하는데 이용될 수 있다. 쿠프레독신 수송 펩티드는 쿠프레독신 침입 도메인을 포함한다. "쿠프레독신 침입 도메인"은 포유동물 암 세포 내로 쿠프레독신의 침입에 필요한 아미노 서열을 포함하는 쿠프레독신의 단편을 지칭한다. 특정 구체예에서, 쿠프레독신 수송 펩티드는 SEQ ID NO: 13-17, 또는 다른 쿠프레독신으로부터 동등한 잔기이다. 본 발명에는 약동학적 특성을 향상시키기 위하여 변형된 화물 화합물과 복합된 쿠프레독신 수송 펩티드가 포함된다. 화물 화합물과 쿠프레독신 수송 펩티드는 약동학적 특성을 향상시키기 위하여 본 명세서에 기술된 방법으로 변형될 수 있다. 이후, 이들 복합체는 암으로 고통받는 환자를 치료하기 위하여 화물 화합물을 포유동물 암 세포 내로 전달하는 본 발명의 방법에 이용될 수 있다. 본 발명의 물질과 방법에 의해 전달되는 화물 화합물에는 단백질, 지단백(lipoprotein), 폴리펩티드, 펩티드, 폴리사카라이드, 안티-센스 핵산을 비롯한 핵산, 염료, 형광 태그와 방사성 태그, 미세입자 또는 나노입자, 독소, 유기와 무기 분자, 소형 분자, 약물이 포함되지만 이들에 국한되지 않는다. 일부 구체예에서, 약물과 독소는 종양 세포를 죽인다. 이들 쿠프레독신 수송 펩티드와 이들로 만들어진 복합체는 U.S. Patent Application No. 11/244,105(2005년 10월 6일 제출됨)에 제시되는데, 상기 문헌은 본 명세서에 참조로서 편입된다.
일부 구체예에서, 소요의 약리 활성을 갖는 쿠프레독신 사이에 보존된 쿠프레독신 유래된 펩티드에서 아미노산 잔기는 향상된 약동학적 특성을 갖는 변형된 쿠프레독신 유래된 펩티드에서 보존된다. 가령, 녹농균(Pseudomonas aeruginosa) 아주린의 쿠프레독신 침입 도메인 내에서, 여러 잔기가 여러 종, 녹농균(Pseudomonas aeruginosa), 슈도모나스 시린가에(Pseudomonas syringae), 임균(Neisseria gonorrhoeae), 장염 비브리오(Vibrio parahaemolyticus)와 보르데텔라 브론키셉티카(Bordetella bronchiseptica)로부터 아주린과 아주린-유사 단백질 사이에 보존되는 것으로 알려져 있다(Yamada et al., Cell. Microbiol. 7:1418-1431 (2005)). 일부 구체예에서, 쿠프레독신 유래된 펩티드는 녹농균(P. aeruginosa) 아주린(SEQ IS NO: 1)의 잔기 62, 63, 69, 72, 74와 77에 해당하는 하나이상의 아미노산 잔기를 보유한다. 다른 구체예에서, 쿠프레독신 펩티드는 보존된 아미노산 서열 DGXXXXXDXXYXKXXD(SEQ ID NO: 46) 또는 DGXXXXDXXYXKXXD(SEQ ID NO: 47)를 포함하는데, 여기서 D는 아스파르트산, G는 글리신, Y는 티로신, K는 리신, X는 임의의 아미노산이다.
변형
본 발명은 쿠프레독신 펩티드의 변이체 또는 유도체이고, 특정 구체예에서, 상기 펩티드의 하나이상의 약리 활성을 유지하고 및/또는 상기 펩티드의 약동학적 특성을 향상시키는 쿠프레독신 유래된 펩티드의 변형에 관계한다. 이들 변형에는 포유동물 암 세포 내로 침입하고 및/또는 포유동물 암 세포의 성장을 저해하는 쿠프레독신의 능력을 유지하면서, 쿠프레독신 유래된 펩티드의 안정성(stability), 고유 활성(specific activity), 혈장 반감기(plasma half-life)를 증가시키고 및/또는 면역원성(immunogenicity)을 감소시키는 이들 펩티드의 변이체와 유도체가 포함되지만 이들에 국한되지 않는다. 이런 변이체에는 펩티드의 가수분해(hydrolysis)를 감소시키고, 펩티드의 탈아민화(deamidation)를 감소시키고, 펩티드의 산화(oxidation)를 감소시키고, 펩티드의 면역원성을 감소시키고 및/또는 펩티드의 구조적 안정성(structural stability)을 증가시키는 변이체가 포함되지만 이들에 국한되지 않는다. 본 명세서에 기술된 2개 이상의 변형이 하나의 변형된 쿠프레독신 유래된 펩티드 내에서 통합될 수 있고, 또한 본 명세서에 기술된 하나이상의 변형이 당분야에 공지된, 약동학적 특성을 향상시키는 다른 변형과 통합될 수도 있다. 이런 변이체와 유도체를 설계하는 다양한 방법이 당분야에 공지되어 있다.
생체내변화
이들 펩티드의 약동학적 특성을 향상시키는 한 가지 접근법은 생체내변화에 덜 민감한, 쿠프레독신 유래된 펩티드의 변이체와 유도체를 산출하는 것이다. 생체내변화는 펩티드의 약리 활성을 감소시키고, 또한 환자 신체로부터 제거되는 속도를 증가시킬 수 있다. 이를 달성하는 한 가지 방법은 생체내변화될 가능성이 가장 높은 아미노산 및/또는 아미노산 서열을 결정하고, 이들 아미노산을 특정의 변화 과정(transformative process)에 민감하지 않은 아미노산으로 치환하는 rsjt이다.
가수분해는 일반적으로, 아스파라진산염을 보유하는 펩티드에서 문제가 된다. 아스파라진산염은 탈수(dehydration)에 민감하고 환형 이미드 중간물질(cyclic imide intermediate)을 형성하는데, 이로 인하여 아스파라진산염은 잠재적으로 불활성 이소-아스파라진산염 유사체로 전환되고, 궁극적으로 펩티드 사슬이 절단된다. 가령, 펩티드 서열 내에 아스파르트산--프롤린의 존재에서, 환형 이미드 중간물질의 산 촉매된 형성은 펩티드 사슬의 절단을 유발할 수 있다. 유사하게, 펩티드 서열 내에 아스파르트산--글리신의 존재에서, 이러한 환형 중간물질은 최초 아스파라진산염 형태(무해함) 또는 이소-아스파라진산염 유사체로 가수분해될 수 있다. 궁극적으로, 모든 아스파라진산염 형태가 이소-아스파라진산염 유사체로 완전히 전환될 수 있다. 유사하게, 세린을 보유하는 서열 역시 탈수되어 환형 이미드 중간물질을 형성할 수 있는데, 이러한 중간물질은 펩티드 사슬을 절단할 수 있다. 펩티드의 절단은 상기 펩티드의 감소된 혈장 반감기와 감소된 특이적인 약리 활성을 유발할 수 있다.
쿠프레독신 유래된 펩티드의 서열 내에서 아스파라긴 및/또는 세린에 대한 다른 아미노산 치환은 향상된 약동학적 특성, 예를 들면, 더욱 긴 혈장 반감기와 약리 활성의 증가된 고유 활성을 갖는 펩티드를 결과할 것으로 고려된다. 한 가지 고려된 변이체에서, 쿠프레독신 유래된 펩티드의 하나이상의 아스파라긴 잔기가 다른 아미노산 잔기, 특히, 글루타민산 잔기로 치환된다. 다른 고려된 변이체에서, 쿠프레독신 유래된 펩티드의 하나이상의 세린 잔기가 다른 아미노산 잔기, 특히, 트레오닌 잔기로 치환된다. 쿠프레독신 유래된 펩티드의 일부 변이체에서, 하나이상의 아스파라긴 잔기와 하나이상의 세린 잔기가 치환된다. 일부 구체예에서, 보존성 치환(conservative substitution)이 만들어진다. 다른 구체예에서, 비-보존성 치환(non-conservative substitution)이 만들어진다.
아미노산 잔기의 탈아미드화(deamidation)는 생체내변화에서 중요한 문제점이다. 이러한 염기-촉매된 반응은 아스파라긴--글리신 또는 글루타민--글리신을 보유하는 서열에서 빈번하게 발생하고, 상기 아스파르트산--글리신 서열에서와 유사한 기전을 추종한다. 아스파라긴--글리신 서열의 탈아미드화는 환형 이미드 중간물질을 형성하고, 상기 중간물질은 차후에, 가수분해되어 아스파라긴의 아스파라진산염 또는 이소-아스파라진산염 유사체를 형성한다. 이에 더하여, 이러한 환형 이미드 중간물질은 아스파라긴의 D-아스파르트산 또는 D-이소-아스파르트산 유사체로 라세미화를 유발할 수 있는데, 이들 모두 잠재적으로, 상기 펩티드의 불활성 형태로 귀결될 수 있다.
쿠프레독신 펩티드에서 탈아미드화는 쿠프레독신의 아스파라긴--글리신 또는 글루타민―글리신 서열의 글리신, 아스파라긴 및/또는 글루타민을 다른 아미노산으로 치환함으로써 예방될 수 있고, 이는 향상된 약동학적 특성, 예를 들면, 더욱 긴 혈장 반감기와 약리 활성의 증가된 고유 활성을 갖는 펩티드를 결과할 것으로 고려된다. 일부 구체예에서, 쿠프레독신 유래된 펩티드의 하나이상의 글리신 잔기가 다른 아미노산 잔기로 치환된다. 특정 구체예에서, 쿠프레독신 유래된 펩티드의 하나이상의 글리신 잔기가 트레오닌 또는 알라닌 잔기로 치환된다. 일부 구체예에서, 쿠프레독신 유래된 펩티드의 하나이상의 아스파라긴 또는 글루타민 잔기가 다른 아미노산 잔기로 치환된다. 특정 구체예에서, 쿠프레독신 유래된 펩티드의 하나이상의 아스파라긴 또는 글루타민 잔기가 알라닌 잔기로 치환된다. 다른 특정 구체예에서, 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 잔기 58 및/또는 63에서 글리신, 또는 다른 쿠프레독신의 동등한 글리신이 알라닌 또는 트레오닌으로 치환된다. 다른 특정 구체예에서, 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 잔기 59에서 메티오닌, 또는 다른 쿠프레독신 유래된 펩티드의 동등한 메티오닌 잔기가 알라닌 잔기로 치환된다. 다른 특정 구체예에서, 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 잔기 63에서 글리신, 또는 다른 쿠프레독신 유래된 펩티드의 동등한 글리신 잔기가 트레오닌 잔기로 치환된다. 일부 구체예에서, 보존성 치환이 만들어진다. 다른 구체예에서, 비-보존성 치환이 만들어진다. 특정 구체예에서, 본 발명의 변형된 쿠프레독신 유래된 펩티드는 아래의 서열을 포함하는데, 여기서 밑줄로 표시된 아미노산이 야생형 녹농균(Pseudomonas aeruginosa) 아주린 서열 내로 치환된다:
LSTAADMQAVVTDTMASGLDKDYLKPDD(SEQ ID NO: 30).
아미노산의 가역성(reversible)과 비가역성(irreversible) 산화는 쿠프레독신 유래된 펩티드의 약리 활성 및/또는 혈장 반감기를 감소시키는 문제점을 유발하는 다른 생체내변화 과정이다. 시스테인과 메티오닌 잔기는 가역성 산화가 진행되는 유력한 잔기이다. 시스테인의 산화는 더욱 높은 pH에서 가속화되는데, 여기서 티올은 더욱 쉽게 탈양성자화(deprotonation)되고, 사슬내(intra-chain) 또는 사슬간(inter-chain) 이황화 결합(disulfide bond)을 용이하게 형성한다. 이들 이황화 결합은 디티오트레이톨(dithiothreitol, DTT) 또는 트리스(2-카르복시에틸포스핀) 염산염(tris(2-carboxyethylphosphine) hydrochloride, TCEP) 처리로 시험관내에서 용이하게 역진될 수 있다. 메티오닌은 화학적 경로와 광화학 경로 둘 모두에 의해 산화되어 메티오닌 술폭시드를 형성하고 메티오닌 술폰으로 더욱 산화되는데, 이들 둘 모두 역진이 거의 불가능하다.
쿠프레독신 유래된 펩티드 내에서 산화는 메티오닌 및/또는 시스테인 잔기를 다른 잔기로 치환함으로써 예방될 것으로 고려된다. 일부 구체예에서, 쿠프레독신 유래된 펩티드의 하나이상의 메티오닌 및/또는 시스테인 잔기가 다른 아미노산 잔기로 치환된다. 특정 구체예에서, 메티오닌 잔기가 루이신 또는 발린 잔기로 치환된다. 다른 특정 구체예에서, 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 잔기 56과 64에서 하나이상의 메티오닌, 또는 다른 쿠프레독신 유래된 펩티드에서 동등한 메티오닌 잔기가 루이신 또는 발린으로 치환된다. 일부 구체예에서, 보존성 치환이 만들어진다. 다른 구체예에서, 비-보존성 치환이 만들어진다. 특정 구체예에서, 본 발명의 쿠프레독신 펩티드는 아래의 서열 중에서 하나를 포함하는데, 여기서 밑줄로 표시된 아미노산이 야생형 녹농균(Pseudomonas aeruginosa) 아주린 서열 내로 치환된다:
LSTAADLQGVVTDGLASGLDKDYLKPDD(SEQ ID NO: 31) 또는
LSTAADVQGVVTDGVASGLDKDYLKPDD(SEQ ID NO: 32).
쿠프레독신 유래된 펩티드의 약리 활성, 혈장 반감기 및/또는 면역원성에 영향을 주는 다른 생체내변화 과정은 디켑토피페라진(diketopiperazine)과 피로글루타민산(pyroglutamic acid) 형성이다. 디켑토피페라진 형성은 일반적으로, 글리신이 N-말단으로부터 세 번째 위치에 존재할 때, 특히, 프롤린 또는 글리신이 위치 1 또는 2에 존재할 때 발생한다. 이러한 반응은 두 번째와 세 번째 아미노산 사이에 아마이드 카르보닐(amide carbonyl)에서 N-말단 질소의 친핵성 공격(nucleophilic attack)을 수반하는데, 이는 디켑토피페라진의 형태로 첫 2개 아미노산의 절단을 유발한다. 다른 한편, 피로글루타민산(pyroglutamic acid) 형성은 글루타민이 N-말단에 존재하면 거의 필연적이다. 이는 상기와 유사한 반응인데, N-말단 질소가 글루타민의 측쇄(side chain) 카르보닐 탄소를 공격하여 탈아민화된 피로글루타마일(pyroglutamayl) 펩티드 유사체를 형성한다. 이러한 전환은 정도가 덜하긴 하지만, N-말단에서 아스파라긴을 보유하는 펩티드에서 발생한다.
디켑토피페라진(diketopiperazine)과 피로글루타민산(pyroglutamic acid) 형성은 쿠프레독신 유래된 펩티드 내에서, N-말단으로부터 위치 1, 2, 또는 3에서 글리신, N-말단으로부터 위치 3에서 프롤린, 또는 상기 펩티드의 N-말단에서 아스파라긴을 다른 아미노산 잔기로 치환함으로써 감소될 것으로 고려된다. 일부 구체예에서, 쿠프레독신 유래된 펩티드의 N-말단으로부터 위치 1, 2, 또는 3에서 글리신이 다른 아미노산 잔기로 치환된다. 특정 구체예에서, 글리신 잔기가 트레오닌 또는 알라닌 잔기로 치환된다. 다른 구체예에서, 쿠프레독신 유래된 펩티드의 N-말단으로부터 위치 3에서 프롤린이 다른 아미노산 잔기로 치환된다. 특정 구체예에서, 프롤린이 알라닌 잔기로 치환된다. 다른 구체예에서, N-말단에서 아스파라긴이 다른 아미노산 잔기로 치환된다. 특정 구체예에서, 아스파라긴 잔기가 글루타민 잔기로 치환된다. 일부 구체예에서, 보존성 치환이 만들어진다. 다른 구체예에서, 비-보존성 치환이 만들어진다.
쿠프레독신 유래된 펩티드의 약리 활성, 혈장 반감기 및/또는 면역원성에 영향을 주는 다른 생체내변화 과정은 라세미화이다. 상기 용어는 광의로써, 아미노산 또는 펩티드의 키랄 완전성(chiral integrity)의 전면적인 상실을 지칭하는데 이용된다. 라세미화는 아미노산의 한 이성질체(일반적으로, L-형태)의 L-과 D-거울상이성질체의 1:1 혼합물로의 염기-촉매된 전환을 수반한다. 펩티드의 안정성을 향상시키는 한 가지 방법은 일반적으로, retro-inverso(D-이성질체) 펩티드를 만드는 것이다. 펩티드 구조의 이러한 이중 반전(double inversion)은 종종, 측쇄의 표면 위상(surface topology)을 본래 상태로 유지시키고, 생물학적 활성 펩티드를 안정화시키는데 폭넓게 이용되고 있다(Snyder et al., PLoS Biol. 2:0186-0193 (2004). L-아미노산 펩티드뿐만 아니라 D-아미노산 치화된 Tat가 세포 내로 내재화된다(Futaki et al., J. Biol. Chem. 276:5836-5840 (2001); Huq et al., Biochemistry 38:5172-5177 (1999)). 일부 구체예에서, 쿠프레독신 유래된 펩티드의 하나이상의 아미노산 잔기가 상기 아미노산 잔기의 D-이성질체로 치환된다. 다른 구체예에서, 쿠프레독신 유래된 펩티드의 모든 아미노산 잔기가 이들 잔기의 D-이성질체로 치화된다. 한 구체예에서, 변형된 쿠프레독신 유래된 펩티드는 retro-inverso(D-이성질체) 변형의 쿠프레독신 유래된 펩티드이다. 특정 구체예에서, 변형된 쿠프레독신 유래된 펩티드는 DDPKLYDKDLGSAMGDTVVGQMDAATSL(SEQ ID NO: 45)이다.
생체내변화 변성으로부터 쿠프레독신 유래된 펩티드를 보호하는 다른 방법은 N-아세틸화(acetylation)와 C-아미드화(amidation)이다. 이들 유도체는 변성으로부터 상기 펩티드를 보호하고, 쿠프레독신 유래된 펩티드가 고유 단백질에서 알파 아미노와 카르복실 기의 전하 상태(charge state)를 더욱 가깝게 모방할 수 있도록 한다. N-아세틸화 및/또는 C-아미드화를 갖는 펩티드는 상업적 공급업자에 의해 제공될 수 있다. 본 발명의 한 구체예에서, 쿠프레독신 유래된 펩티드의 N-말단이 아세틸화된다. 본 발명의 다른 구체예에서, 쿠프레독신 유래된 펩티드의 C-말단이 아미드화된다. 특정 구체예에서, 변형된 쿠프레독신 유래된 펩티드는 아세틸화-LSTAADMQGVVTDGMASGLDKDYLKPDD-아미드화(SEQ ID NO: 33)이다.
3차 구조 안정화
쿠프레독신 유래된 펩티드의 3차 구조의 안정성은 약리 활성, 혈장 반감기 및/또는 면역원성을 비롯한 약동학의 다양한 측면에 영향을 줄 것이다(참조: Kanovsky et al., Cancer Chemother. Pharmacol. 52:202-208 (2003); Kanovsky et al., PNAS 23:12438-12443 (2001)). 펩티드 나선은 종종, 무작위 코일로 갈라지고, 프로테아제 공격에 더욱 민감해지고 세포막 충분히 침투하지 못한다(Schafmeister et al., J. Am. Chem. Soc. 122:5891-5892 (2000)). 이런 이유로, 펩티드의 전체 구조를 안정화시키는 한 가지 방법은 펩티드의 α-나선 구조를 안정화시키는 것이다. 나선 형성과 연관된 분자내 수소 결합(intra-molecular hydrogen bonding)은 극성 아마이드 골격의 노출을 감소시켜 수송 펩티드에서 막 침투에 대한 장벽을 감소시키고, 따라서 관련된 약리 활성을 증가시키고 프로테아제 절단에 대한 펩티드의 저항성을 증가시킨다(Id). 녹농균(Pseudomonas aeruginosa) 아주린(SEQ ID NO: 1)은 잔기 53-56, 58-64와 68-70에서 α-나선을 갖는다.
α-나선을 안정화시키는 한 가지 방법은 α-나선 내에서, 나선 파괴 아미노산 잔기, 예를 들면, 글리신, 프롤린, 세린과 아스파르트산, 또는 나선 중성 아미노산 잔기, 예를 들면, 알라닌, 트레오닌, 발린, 글루타민, 아스파라긴, 시스테인, 히스티딘, 리신 또는 아르기닌을 나선 형성 잔기, 예를 들면, 루이신, 이소루이신, 페닐알라닌, 글루타민산, 티로신, 트립토판과 메티오닌으로 치환하는 것이다. 쿠프레독신 유래된 펩티드의 이들 α-나선은 하나이상의 글리신, 프롤린, 세린 및/또는 아스파르트산 잔기를 다른 아미노산으로 치환함으로써 안정화될 수 있다. 특정 구체예에서, 글리신, 프롤린, 세린, 아스파르트산, 알라닌, 트레오닌, 발린, 글루타민, 아스파라긴, 시스테인, 히스티딘, 리신 및/또는 아르기닌 잔기는 루이신, 이소루이신, 페닐알라닌, 글루타민산, 티로신, 트립토판 및/또는 메티오닌 잔기로 치환된다(참조: Lee et al., Cancer Cell Intl. 11:21 (2005)). 다른 특정 구체예에서, 쿠프레독신 유래된 펩티드의 α-나선 내에서 하나이상의 세린 또는 글루타민 잔기가 치환된다. 또 다른 특정 구체예, 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 잔기 53-56, 58-64와 68-70, 또는 다른 쿠프레독신 유래된 펩티드의 동등한 잔기 내에서 세린 및/또는 글루타민 잔기가 치환된다. 다른 특정 구체예에서, 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 아미노산 잔기 57, 또는 다른 쿠프레독신 유래된 펩티드의 동등한 잔기에서 글루타민 잔기가 치환되고, 더욱 구체적으로, 트립토판으로 치환된다. 다른 특정 구체예에서, 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 아미노산 잔기 52, 또는 다른 쿠프레독신 유래된 펩티드의 동등한 잔기에서 트레오닌 잔기가 치환되고, 더욱 구체적으로, 트립토판으로 치환된다. 다른 특정 구체예에서, 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 아미노산 잔기 61, 또는 다른 쿠프레독신 유래된 펩티드의 동등한 잔기에서 트레오닌 잔기가 치환되고, 더욱 구체적으로, 트립토판으로 치환된다. 다른 특정 구체예에서, 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 아미노산 잔기 63, 또는 다른 쿠프레독신 유래된 펩티드의 동등한 잔기에서 글리신 잔기가 치환되고, 더욱 구체적으로, 트립토판으로 치환된다. 다른 특정 구체예에서, 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 아미노산 잔기 52, 57, 61 또는 63, 또는 다른 쿠프레독신 유래된 펩티드의 동등한 잔기에서 하나이상의 트레오닌, 글루타민 또는 글리신 잔기가 치환되고, 더욱 구체적으로, 트립토판으로 치환된다. 특정 구체예에서, 쿠프레독신 펩티드는 아래의 서열 중에서 하나를 포함하는데, 여기서 밑줄로 표시된 아미노산이 야생형 녹농균(Pseudomonas aeruginosa) 아주린 서열 내로 치환된다:
LSWAADMQGVVTDGMASGLDKDYLKPDD(SEQ ID NO: 34);
LSTAADMWGVVTDGMASGLDKDYLKPDD(SEQ ID NO: 35);
LSTAADMQGVVWDGMASGLDKDYLKPDD(SEQ ID NO: 36);
LSTAADMQGVVTDWMASGLDKDYLKPDD(SEQ ID NO: 37);
LSWAADMWGVVTDGMASGLDKDYLKPDD(SEQ ID NO: 38);
LSWAADMQGVVWDGMASGLDKDYLKPDD(SEQ ID NO: 39);
LSWAADMQGVVTDWMASGLDKDYLKPDD(SEQ ID NO: 40);
LSTAADMWGVVWDGMASGLDKDYLKPDD(SEQ ID NO: 41);
LSTAADMWGVVTDWMASGLDKDYLKPDD(SEQ ID NO: 42);
LSTAADMQGVVWDWMASGLDKDYLKPDD(SEQ ID NO: 43); 또는
LSWAADMWGVVWDWMASGLDKDYLKPDD(SEQ ID NO: 44).
다른 구체예에서, 다른 쿠프레독신 유래된 펩티드에서 동등한 아미노산이 트립토판으로 치환된다.
α-나선 3차 구조를 안정화시키는 다른 방법은 π-스태킹(stacking)이 가능한 비자연 아미노산 잔기의 이용을 수반한다. 가령, Andrews and Tabor, Tetrahedron 55:11711-11743 (1999)에서, ε-(3,5-디니트로벤조일)-Lys 잔기의 쌍이 상이한 간격에서 펩티드의 α-나선 영역 내로 치환되었다. 전체 결과는 i,(i+4) 간격이 가장 효과적인 안정화 정렬(stabilizing arrangement)임을 증명하였다. 최대 90%까지 수분 비율의 증가는 펩티드의 나선 용량(helical content)을 증가시켰다. 동일한 i,(i+4) 간격에서 ε-아실-Lys 잔기의 쌍은 안정화 효과가 없었는데, 이는 대부분의 안정화가 π-π 상호작용에 기인한다는 것을 암시하였다. 한 구체예에서, 쿠프레독신 유래된 펩티드는 리신 잔기가 ε-(3,5-디니트로벤조일)-Lys 잔기에 의해 치환되도록 변형된다. 특정 구체예에서, 리신 잔기는 i,(i+4) 간격에서 ε-(3,5-디니트로벤조일)-Lys에 의해 치환된다.
α-나선 3차 구조를 안정화시키는 다른 방법은 α-나선에서 측쇄(side-chain) 사이에 정전 상호작용(electrostatic interaction)을 이용한다. His-Cys 또는 His-His 잔기 쌍이 i,(i+4) 정렬에서 펩티드 내로 치환될 때, 이들 펩티드는 Cu, Zn 또는 Cd 이온의 첨가후 대략 50% 나선에서 대략 90% 나선으로 변하였다. 루테늄(ruthenium)(Ru) 염이 His-His 펩티드에 첨가될 때, 나선 안정성(helix stability)이 향상된 교환-불활성(exchange-inert) 복합체, 거대환(macrocyclic) cis-[Ru-(NH3)4L2]3+ 복합체가 형성되는데, 여기서 L2는 2개 히스티딘의 측쇄이다(Ghadiri and Fernholz, J. Am. Chem. Soc. 112, 9633-9635 (1990). 일부 구체예에서, 쿠프레독신 유래된 펩티드는 거대환 cis-[Ru-(NH3)4L2]3+ 복합체를 포함하는데, 여기서 L2는 2개 히스티딘의 측쇄이다. 일부 구체예에서, 하나이상의 히스티딘-시스테인 또는 히스티딘-히스티딘 잔기 쌍이 i,(i+4) 정렬에서, 쿠프레독신 유래된 펩티드의 α-나선 내로 치환된다. 다른 구체예에서, 하나이상의 히스티딘-시스테인 또는 히스티딘-히스티딘 잔기 쌍이 i,(i+4) 정렬에서, 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 잔기 53-56, 58-64와 68-70, 또는 다른 쿠프레독신 유래된 펩티드의 동등한 잔기 내로 치환된다. 일부 구체예에서, 쿠프레독신 유래된 펩티드는 Cu, Zn, Cd 및/또는 Ru 이온을 더욱 포함한다.
α-나선 3차 구조를 안정화시키는 다른 방법은 α-나선의 측쇄 사이에 이황화 결합(disulfide bond) 형성을 수반한다. 또한, 펩티드 서열 내에서 분리된 잔기 사이에 정연한 공유 결합(covalent bond)의 수단으로 나선 구조를 안정화시키는 것도 가능하다. 통상적으로 이용되는 자연적인 방법은 이황화 결합을 이용하는 것이다(Pierret et al., Intl. J. Pept. Prot. Res., 46:471-479 (1995)). 일부 구체예에서, 하나이상의 시스테인 잔기 쌍이 쿠프레독신 유래된 펩티드의 α-나선 내로 치환된다. 다른 구체예에서, 하나이상의 시스테인 잔기 쌍이 녹농균(P. aeruginosa)아주린(SEQ ID NO: 1)의 잔기 53-56, 58-64와 68-70, 또는 다른 쿠프레독신 유래된 펩티드의 동등한 잔기에서 치환된다.
α-나선 3차 구조를 안정화시키는 다른 방법은 전체-탄소 가교-링크(all-carbon cross-link) 방법이다. 전체-탄화수소 가교-링크(all-hydrocarbon cross-link) 방법은 나선 구조의 안정화, 프로테아제 저항성과 세포-침투성(cell-permeability)을 증가시키는 것으로 증명되었다(Walensky et al., Science, 305, 1466-1470 (2004)). 올레핀-보유 테터를 보유하는 α,α-이중치환된 비-자연 아미노산이 펩티드 내로 통합된다. 루테늄 촉매된 올레핀 전이(metathesis)는 나선을 가교-연결시키는 전체-탄화수소 "스페이플(staple)"을 산출한다(Schafmeister et al., J. Am. Chem. Soc., 122, 5891-5892 (2000); Walensky et al., id.). 올레핀-보유 테터를 보유하는 비-자연 아미노산은 Schafmeister et al. (id.)과 Williams and Im, J. Am. Chem. Soc., 113:9276-9286 (1991)에 제시된 방법에 따라 합성될 수 있다. 일부 구체예에서, 쿠프레독신 유래된 펩티드는 전체-탄화수소 스테이플에 의해 안정화된다. 특정 구체예에서, 고유 아미노산에 상응하는 올레핀-보유 테터를 보유하는 α,α-이중치환된 비-자연 아미노산의 하나이상의 쌍이 쿠프레독신 유래된 펩티드의 α-나선 내로 치환된다. 다른 구체예에서, 고유 아미노산에 상응하는 올레핀-보유 테터를 보유하는 α,α-이중치환된 비-자연 아미노산의 하나이상의 쌍이 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 잔기 53-56, 58-64와 68-70, 또는 다른 쿠프레독신 유래된 펩티드의 동등한 잔기 내로 치환된다.
일부 구체예에서, 변형된 쿠프레독신 유래된 펩티드는 X1SX2AADX3X4X5VVX6DX7X8ASGLDKDYLKPDX9(SEQ ID NO:48)를 포함하는데, 여기서 X1은 L 또는 아세틸화된-L이고, X2는 T 또는 W이고, X3은 M, L 또는 V이고, X4는 Q 또는 W이고, X5는 G 또는 A이고, X6은 T 또는 W이고, X7은 G, T 또는 W이고, X8은 M, L 또는 V이고, X9는 D 또는 아미드화된-D이다. 다른 구체예에서, 변형된 쿠프레독신 유래된 펩티드는 X1SX2AADX3X4X5VVX6DX7X8ASGLDKDYLKPDX9(SEQ ID NO:48)로 구성되는데, 여기서 X1은 L 또는 아세틸화된-L이고, X2는 T 또는 W이고, X3은 M, L 또는 V이고, X4는 Q 또는 W이고, X5는 G 또는 A이고, X6은 T 또는 W이고, X7은 G, T 또는 W이고, X8은 M, L 또는 V이고, X9는 D 또는 아미드화된-D이다. 다른 구체예에서, 변형된 쿠프레독신 유래된 펩티드는 X1DPKLYDKDLGSAX2X3DX4VVX5X6X7DAAX8SX9(SEQ ID NO:49)를 포함하는데, 여기서 X1은 D 또는 아세틸화된-D이고, X2는 M, L 또는 V이고, X3은 G, T 또는 W이고, X4는 T 또는 W이고, X5는 G 또는 A이고, X6은 Q 또는 W이고, X7은 M, L 또는 V이고, X8은 T 또는 W이고, X9는 L 또는 아미드화된-L이다. 다른 구체예에서, 변형된 쿠프레독신 유래된 펩티드는 X1DPKLYDKDLGSAX2X3DX4VVX5X6X7DAAX8SX9(SEQ ID NO:49)로 구성되는데, 여기서 X1은 D 또는 아세틸화된-D이고, X2는 M, L 또는 V이고, X3은 G, T 또는 W이고, X4는 T 또는 W이고, X5는 G 또는 A이고, X6은 Q 또는 W이고, X7은 M, L 또는 V이고, X8은 T 또는 W이고, X9는 L 또는 아미드화된-L이다. 목적하는 특이적인 펩티드는 표 3에 열거된다.
PEGy화
치료 또는 진단에 중요한 약물에 PEG에 공유 부착(covalent attachment)은 생체내에서 약물의 혈장 반감기를 연장시키고 및/또는 이들의 면역원성(immunogenicity)과 항원성(antigenicity)을 감소시켰다(Harris and Chess, Nature Reviews Drug Discovery 2:214-221 (2003)). 가령, PEG 부착은 인터루킨(interleukin)(Kaufman et al., J. Biol. Chem. 263:15064 (1988); Tsutsumi et al., J. Controlled Release 33:447 (1995)), 인터페론(interferon)(Kita et al., Drug Des. Delivery 6:157 (1990)), 카탈라아제(catalase)(Abuchowski et al., J. Biol. Chem. 252:3582 (1977)), 슈퍼옥시드 디스뮤타아제(superoxide dismutase) (Beauchamp et al., Anal. Biochem. 131:25 (1983))와 아데노신 데아미나아제(adenosine deaminase)(Chen et al., Biochem. Biophys. Acta 660:293 (1981))를 비롯한 다양한 치료 단백질의 약동학적 특성을 향상시켰다. FDA는 식품, 화장품 및 주사(injectable), 국소(topical), 직장(rectal)과 비강(nasal) 제제(formulation)를 비롯한 의약품에서 운반제(vehicle) 또는 기부(base)로서 PEG의 이용을 승인하였다. PEG는 독성이 거의 없고, 신장에 의해(PEG < 30 kDa의 경우) 또는 소변으로(PEG > 20 kDa의 경우) 본래 상태로 신체로부터 제거된다. PEG는 물에서 고도 수용성이다.
치료 펩티드의 PEG화는 신장 한외여과(renal ultrafiltration)를 감소시킴으로써 환자의 혈류 내에서 펩티드의 수명을 증가시키고, 따라서 신체로부터 약물의 제거를 감소시키는데 이용될 수 있다. 전하 마스킹(charge masking)이 신장 투과(renal permeation)에 영향을 줄 수 있다. 전하 마스킹은 단백질 이온화가능 기능기, 다시 말하면, 아민(amine) 또는 카르복실(carboxyl)의 paramchemical 변형의 결과일 수 있다. 특히, 단백질-PEG 유도체를 생산하는 가장 일반적인 절차는 양성 전하의 상실과 함께 단백질 아미노기의 아마이드로의 전환을 수반하는데, 이는 단백질 한외여과를 변화시킬 수 있다. 음이온성 거대분자(anionic macromolecule)가 중성 또는 양성 거대분자보다 신장 한외여과에 의해 더욱 느리게 제거되는 것으로 밝혀졌기 때문에, 아미노기에 PEG 결합(conjugation)은 혈류 내에서 PEG화된 펩티드의 존재를 연장시키는 것으로 예상될 수 있었다.
분자 크기와 구 한외여과(globular ultrafiltration) 역시 치료 펩티드의 신장 한외여과에 영향을 줄 수 있다. 고유 구 단백질의 신장 제거를 위한 분자량 컷오프(molecular weight cut off)는 대략 70 kDa인 것으로 간주되는데, 이는 혈청 알부민의 분자량에 가깝다. 따라서, 70 kDa를 초과하는 분자량을 갖는 단백질은 주로, 신장 한외여과 이외의 경로, 예를 들면, 간 흡수(liver uptake), 단백분해 절단(proteolytic digestion) 및 면역계(immune system)에 의한 제거에 의해 신체로부터 제거된다. 이런 이유로, PEG화에 의한 치료 펩티드의 크기 증가는 환자의 혈류로부터 상기 펩티드의 신장 한외여과를 감소시킨다.
부가적으로, 치료 펩티드의 PEG화는 펩티드의 면역원성을 감소시키고, 또한 단백분해 효소(proteolytic enzyme), 식세포(phagocytic cell) 및 치료 펩티드와의 직접적인 접촉을 요하는 다른 인자로부터 상기 펩티드를 보호한다. 특히, 가지형 PEG의 우산-유사 구조는 접근하는 단백분해 효소, 항체, 식세포 등으로부터, 선형 PEG보다 더욱 우수한 보호를 제공하는 것으로 밝혀졌다(Caliceti and Veronese, Adv. Drug. Deliv. Rev. 55:1261-12778 (2003)).
일부 구체예에서, 쿠프레독신 유래된 펩티드는 하나이상의 PEG 분자가 시스테인 분자에 공유 결합되도록 변형된다. 이러한 공유 결합은 PEG 분자에서 쿠프레독신 유래된 펩티드로 직접적인 공유 결합일 필요가 없으며, 서로 및/또는 쿠프레독신 유래된 펩티드에 공유 결합되는 하나이상의 링커 분자에 공유 결합될 수 있다. 일부 구체예에서, 쿠프레독신 유래된 펩티드는 부위-특이적인 PEG화를 갖는다. 특정 구체예에서, PEG 분자는 녹농균(P. aeruginosa) 아주린(SEQ ID NO: 1)의 시스테인 잔기 3, 26 및/또는 112에 공유 결합된다. 다른 구체예에서, 하나이상의 시스테인 잔기가 쿠프레독신 유래된 펩티드 내로 치환되고 PEG화된다. 일부 구체예에서, 쿠프레독신 유래된 펩티드를 PEG화하는 방법은 특히, NHS, 환원성 아민화(reductive animation), 말리미드(malimid) 또는 에폭시드(epoxid)이다. 다른 구체예에서, 쿠프레독신 유래된 펩티드는 하나이상의 리신, 시스테인, 히스티딘, 아르기닌, 아스파르트산, 글루타민산, 세린, 트레오닌, 또는 티로신, 또는 N-말단 아미노기, 또는 C-말단 카르복실산에서 PEG화된다. 또 다른 특정 구체예에서, 쿠프레독신 유래된 펩티드는 하나이상의 리신 또는 N-말단 아미노기에서 PEG화된다. 다른 구체예에서, 하나이상의 리신, 시스테인, 히스티딘, 아르기닌, 아스파르트산, 글루타민산, 세린, 트레오닌, 또는 티로신 잔기가 쿠프레독신 유래된 펩티드 내로 치환되고 PEG화된다. 다른 구체예에서, 쿠프레독신 유래된 펩티드는 하나이상의 아미노기에서 PEG화된다. 다른 구체예에서, 쿠프레독신 유래된 펩티드는 무작위, 비-부위 특이적인 방식으로 PEG화된다. 일부 구체예에서, 쿠프레독신 유래된 펩티드는 대략 200 달톤 내지 대략 100,000 달톤, 대략 2,000 달톤 내지 대략 20,000 달톤, 또는 대략 2,000 달톤 내지 대략 5,000 달톤의 PEG-기초된 중합체의 평균 분자량을 갖는다. 다른 구체예에서, 쿠프레독신 유래된 펩티드는 하나이상의 가지형 PEG 분자, 구체적으로, 대략 50 kDa의 가지형 PEG 분자를 포함한다. 다른 구체예에서, 쿠프레독신 유래된 펩티드는 하나이상의 선형 PEG 분자, 구체적으로, 대략 5 kDa의 선형 PEG 분자를 포함한다.
쿠프레독신
쿠프레독신은 예로써, 세균 산화 환원 연쇄(redox chain) 또는 광합성(photosynthesis)에 참여하는 전자 전달 특성을 갖는 소형 청동(blue copper) 보유 단백질(10-20 kDa)을 이다. 구리 이온은 단백질 매트릭스(protein matrix)에 의해서만 결합된다. 구리 주변에 2개의 히스티딘과 1개의 시스테인에 독특한 뒤틀린 삼각형 2차원 정렬은 금속 부위의 매우 고유한 전자 특성 및 강렬한 푸른색을 발생시킨다. 다수의 쿠프레독신이 중간 내지 높은 해상도(resolution)에서 결정학적으로 특성화되었다. 쿠프레독신에는 아주린, 플라스토시아닌, 루스티시아닌, 슈도아주린, 아우라시아닌과 아주린-유사 단백질이 포함된다. 본 명세서에서, "쿠프레독신"에는 구리-보유 단백질뿐만 아니라 구리 원자가 존재하지 않는 단백질 형태가 포함된다.
아주린
아주린은 식물과 특정 세균에서 전자 전달에 관여하는 쿠프레독신 집단에 속하는 128개의 아미노산 잔기로 구성되는 구리-보유 단백질이다. 아주린에는 녹농균(P. aeruginosa)(SEQ ID NO: 1)("wt-아주린"), 알칼리게네스 자일로족시단스(Alcaligenes xylosoxidans)와 알칼리게네스 데니트리피칸(Alcaligenes denitrifican)으로부터 유래된 것들이 포함된다(Murphy et al., J. Mol. Biol. 315:859-71 (2002)). 이들 아주린 사이에 아미노 서열 동일성이 60-90% 사이에서 변하긴 하지만, 이들 분자는 강한 구조적 상동성을 나타낸다. 모든 아주린은 그리스 열쇠 모티프를 포함하는 특징적인 β-샌드위치를 보유하고, 단일 구리 원자는 상기 단백질의 동일 영역에 항상 위치한다. 이에 더하여, 아주린은 구리 부위를 둘러싸는 본질적으로 중성의 소수성 패치를 보유한다(Murphy et al.).
플라스토시아닌
플라스토시아닌은 진핵 식물과 남조류(cyanobacteria)에서 발견되는 쿠프레독신이다. 이들은 한 분자당 하나의 구리 분자를 보유하고 산화된 형태에서 푸른빛을 띤다. 이들은 엽록소(chloroplast)에서 생성되는데, 여기서 이들은 전자 운반체(electron carrier)로서 기능한다. 1978년에 포플러 플라스토시아닌 구조의 결정이후, 조류(떼목말(Scenedesmus), 파래속(Enteromorpha), 클라미도모나스(Chlamydomonas))와 식물(강낭콩(French bean)) 플라스토시아닌의 구조가 결정학적 방법 또는 NMR 방법으로 결정되었는데, 이러한 포플러 구조는 1.33 Å 해상도에서 세밀히 구별되었다. SEQ ID NO: 2에서는 시아노박테리아인 포르미디움 라미노섬(Phormidium laminosum)으로부터 플라스토시아닌의 아미노산 서열을 도시한다.
조류와 관속 식물(vascular plants)의 플라스토시아닌 사이에 서열 불일치(sequence divergence)(가령, 클라미도모나스(Chlamydomonas)와 포플러 단백질 사이에 62% 서열 동일성)에도 불구하고, 3차원 구조가 보존된다(가령, 클라미도모나스(Chlamydomonas)와 포플러 단백질 사이에 C 알파 위치에서 0.76 Å rms 편차). 구조적 특징에는 8개-가닥 역평행 베타-배럴(beta-barrel)의 한 단부에서 뒤틀린 4배위자리(tetrahedral) 구리 결합 부위, 현저한 네거티브 패치(negative patch)와 편평한 소수성 표면(hydrophobic surface)이 포함된다. 구리 부위는 전자 전달 기능을 위하여 최적화되고, 네거티브와 소수성 패치는 생리학적 반응 파트너의 인식에 관여하는 것으로 제안된다. 화학적 변형, 교차-결합과 특정부위 돌연변이 유발 실험은 시토크롬 f와의 결합 상호작용에서 네거티브와 소수성 패치의 중요성을 확증하고, 플라스토시아닌에서 2가지 기능적으로 중요한 전자 전달 통로의 모형을 확인하였다. 첫 번째 추정 전자 전달 통로는 상대적으로 짧고(대략 4 Å) 소수성 패치 내에 용제-노출된 구리 리간드 His-87을 수반하는 반면, 다른 통로는 더욱 길고(대략 12-15 Å) 네거티브 패치 내에 거의 보존된 잔기 Tyr-83을 수반한다(Redinbo et al., J. Bioenerg. Biomembr. 26(1):49-66 (1994)).
루스티시아닌
루스티시아닌은 티오바실루스(Thiobacillus)로부터 획득된 청동-보유 단일-사슬 폴리펩티드이다. 티오바실루스 페로옥시단스(Thiobacillus ferrooxidans)로부터 극히 안정한 고도 산성화 쿠프레독신 루스티시아닌(SEQ ID NO: 3)의 산화된 형태의 X-레이 결정 구조는 다파장 비정상 회절(multiwavelength anomalous diffraction)로 결정되었고 1.9 Å 해상도에서 세밀히 구별되었다. 루스티시아닌은 6-개와 7-개 가닥 β-시트로 구성되는 코어 베타-샌드위치 접힘(core beta-sandwich fold)으로 구성된다. 다른 쿠프레독신과 유사하게, 구리 이온은 뒤틀린 4배위자리 내에 정렬된 4개의 보존된 잔기(His85, Cys138, His143, Met148)의 클러스터에 의해 동위(coordination)된다(Walter et al., J. Mol. Biol. 263:730-51 (1996)).
아우라시아닌
아우라시아닌 A, 아우라시아닌 B-1, 아우라시아닌 B-2로 명명된 3개의 소형 청동 단백질이 호열성 녹색 활주 광합성 세균(thermophilic green gliding photosynthetic bacterium) 클로로플렉서스 아우란티아쿠스(Chloroflexus aurantiacus)로부터 분리되었다. 2가지 B 형태는 서로 거의 동일한 특성을 갖지만 A 형태와는 상이하다. 나트륨 도데실 설페이트-폴리아크릴아마이드 겔 전기영동에서, 겉보기 단량체 분자 질량(apparent monomer molecular mass)이 14(A), 18(B-2)과 22(B-1) kDa인 것으로 확인되었다.
아우라시아닌 A의 아미노산 서열은 139개 잔기의 폴리펩티드인 것으로 밝혀졌다(Van Dreissche et al, Protein Science 8:947-957 (1999)). His58, Cys123, His128과 Met132는 이들이 공지된 소형 구리 단백질 플라스토시아닌과 아주린에서처럼 진화적으로 보존된 금속 리간드인 경우에 예상되는 방식으로 일정한 거리를 두고 위치한다. 2차 구조 예측 역시 아우라시아닌이 녹농균(Pseudomonas aeruginosa)으로부터 아주린 및 포플러 잎으로부터 플라스토시아닌의 베타-배럴 구조와 전반적으로 유사한 베타-배럴 구조를 갖는다는 것을 암시한다. 하지만, 아우라시아닌은 양쪽 소형 구리 단백질 서열 부류의 서열 특징을 모두 갖는 것으로 보인다. 아주린의 공통 서열과의 전반적인 유사성은 플라스토시아닌의 공통 서열과의 유사성과 대체로 동일하다(다시 말하면, 30.5%). 아우라시아닌의 N-말단 서열 영역 1-18은 글리신과 하이드록시 아미노산이 눈에 띄게 풍부하다(Id). 클로로플렉서스 아우란티아쿠스(Chloroflexus aurantiacus)로부터 아우라시아닌의 사슬 A에 대한 전형적인 아미노산 서열 SEQ ID NO: 10(NCBI 단백질 Data Bank Accession No. AAM12874)을 참조한다.
아우라시아닌 B 분자는 표준 쿠프레독신 접힘을 보유한다. 클로로플렉서스 아우란티아쿠스(Chloroflexus aurantiacus)로부터 아우라시아닌 B의 결정 구조가 조사되었다(Bond et al., J. Mol. Biol. 306:47-67 (2001)). 부가적인 N-말단 가닥을 제외하고, 상기 분자는 세균 쿠프레독신, 아주린과 매우 유사하다. 다른 쿠프레독신에서처럼, Cu 리간드 중에서 하나는 상기 폴리펩티드의 가닥 4에 위치하고, 다른 3개는 가닥 7과 8 사이의 대형 루프를 따라서 위치한다. Cu 부위 기하학은 3개의 후자 리간드 사이에 아미노산 간격(amino acid spacing)을 참조하여 논의된다. 아우라시아닌 B의 결정학적으로 특성화된 Cu-결합 도메인은 아마도, 막-결합된 여러 다른 전자-전달 단백질 내에서 공지된 테터(tether)와 현저한 서열 동일성을 보이는 N-말단 꼬리에 의해 세포질 막의 주변세포질(periplasmic) 부분에 속박된다. B 형태의 아미노산 서열은 McManus et al., J Biol Chem. 267:6531-6540 (1992)에서 제시된다. 클로로플렉서스 아우란티아쿠스(Chloroflexus aurantiacus)로부터 아우라시아닌의 사슬 B에 대한 전형적인 아미노산 서열 SEQ ID NO: 11(NCBI 단백질 Data Bank Accession No. 1QHQA)을 참조한다.
슈도아주린
슈도아주린은 청동-보유 단일-사슬 폴리펩티드 집단이다. 아크로모박터 시클로클라스테스(Achromobacter cycloclastes)로부터 획득된 슈도아주린의 아미노산 서열은 SEQ ID NO: 4에서 열거된다. 슈도아주린의 X-레이 구조 분석 결과는 슈도아주린이 아주린과의 서열 상동성(sequence homology)이 낮긴 하지만 아주린에 유사한 구조를 갖는다는 것을 보여준다. 2가지 주요한 차이는 슈도아주린과 아주린의 전체 구조 사이에 존재한다. 아주린과 비교하여 슈도아주린에는 2개의 알파-나선으로 구성되는 카르복시 말단 신장이 존재한다. 중간-펩티드 영역에서, 아주린은 슈도아주린에 비하여 연장된 루프를 보유하는데, 이는 짧은 α-나선을 보유하는 플랩(flap)을 형성한다. 구리 원자 부위에서 유일한 주요 차이점은 MET 측쇄의 형태(conformation)와 Met-S 구리 결합 길이인데, 상기 길이는 아주린에서보다 슈도아주린에서 훨씬 짧다.
변형된 쿠프레독신 유래된 펩티드는 표준 기술에 의해 합성될 수 있다. 변이체는 직접적으로, 또는 변형이나 부분적인 치환에 의해 고유 화합물로부터 형성된 아미노산 서열이다. 쿠프레독신의 약리 활성을 무력화시키는, 쿠프레독신 유래된 펩티드의 아미노산 서열에서 변경을 유발하는 쿠프레독신 유래된 펩티드 내로 변화가 도입될 수 있다. "비-필수" 아미노산 잔기는 약리 활성의 무력화 없이 쿠프레독신 유래된 펩티드의 서열로부터 변경될 수 있는 잔기인 반면, "필수" 아미노산 잔기는 이런 약리 활성에 필요하다. "보존성" 치환이 달성될 수 있는 아미노산은 당분야에 널리 공지되어 있다. 유용한 보존성 치환은 표 1, "바람직한 치환"에 도시된다. 한 부류의 아미노산이 동일 유형의 다른 아미노산으로 치환되는 보존성 치환은 이런 치환이 쿠프레독신 유래된 펩티드의 소요의 약리 활성을 무력화시키지 않는다면, 본 발명의 범위 내에 속한다. 변화된 쿠프레독신 유래된 약리 활성을 결과하는 이런 변화는 이런 약리 활성이 인지된다면, 본 발명의 일부로서 고려된다. 일부 구체예에서, 쿠프레독신 유래된 펩티드의 약리 활성은 이러한 펩티드가 유래된 야생형 쿠프레독신의 고유 활성의 대략 5% 이하, 대략 10% 이하, 대략 25% 이하, 대략 50% 이하이다. 쿠프레독신 유래된 펩티드의 고유 활성의 일부 상실은 쿠프레독신 유래된 펩티드에서 다른 향상된 품질, 예를 들면, 더욱 긴 혈장 반감기 또는 감소된 면역원성에 의해 상쇄된다면, 허용될 수 있다.
바람직한 치환
최초 잔기 전형적인 치환 바람직한 치환
Ala (A) Val, Leu, Ile Val
Arg (R) Lys, Gln, Asn Lys
Asn (N) Gln, His, Lys, Arg Gln
Asp (D) Glu Glu
Cys (C) Ser Ser
Gln (Q) Asn Asn
Glu (E) Asp Asp
Gly (G) Pro, Ala Ala
His (H) Asn, Gln, Lys, Arg Arg
Ile (I) Leu, Val, Met, Ala, Phe, Norleucine Leu
Leu (L) Norleucine, Ile, Val, Met, Ala, Phe Ile
Lys (K) Arg, Gln, Asn Arg
Met (M) Leu, Phe, Ile Leu
Phe (F) Leu, Val, Ile, Ala, Tyr Leu
Pro (P) Ala Ala
Ser (S) Thr Thr
Thr (T) Ser Ser
Trp (W) Tyr, Phe Tyr
Tyr (Y) Trp, Phe, Thr, Ser Phe
Val (V) Ile, Leu, Met, Phe, Ala, Norleucine Leu
(1) 폴리펩티드 골격의 구조, 예를 들면, β-시트 또는 α-나선 구조, (2) 전하, (3) 소수성, 또는 (4) 측쇄의 크기에 영향을 주는 "비-보존성 치환"은 쿠프레독신 유래된 펩티드의 약리 활성을 변화시킬 수 있다. 잔기는 표 2에 제시된 바와 같이, 공통의 측쇄 특성에 기초하여 여러 군으로 구분된다. 비-보존성 치환은 한 부류의 구성원을 다른 부류의 구성원으로 교체하는 과정을 수반한다.
한 부류의 아미노산이 상이한 부류의 다른 아미노산으로 치환되는 비-보존성 치환은 이런 치환이 쿠프레독신 유래된 펩티드의 소요의 약리 활성을 무력화시키지 않는다면, 본 발명의 범위 내에 속한다. 변화된 쿠프레독신 유래된 약리 활성을 결과하는 이런 변화는 이런 약리 활성이 인지된다면, 본 발명의 일부로서 고려된다.
아미노산 부류
부류 아미노산
소수성 Norleucine, Met, Ala, Val, Leu, Ile
중성 친수성 Cys, Ser, Thr
산성 Asp, Glu
염기성 Asn, Gln, His, Lys, Arg
교란된 사슬 구조 Gly, Pro
방향족 Trp, Tyr, Phe
쿠프레독신 유래된 펩티드는 당분야에 공지된 방법, 예를 들면, 올리고뉴클레오티드-매개된(특정 부위) 돌연변이유발, 알라닌 스캐닝과 PCR 돌연변이유발을 이용하여 변형할 수 있다. 클론된 DNA에서 특정 부위 돌연변이유발(Carter, Biochem J. 237:1-7(1986); Zoller and Smith, Methods Enzymol., 154:329-50(1987)), 카세트 돌연변이유발(cassette mutagenesis), 제한 선별 돌연변이유발(restriction selection mutagenesis)(Wells et al., Gene 34:315-23 (1985)), 또는 다른 공지된 기술을 수행하여 쿠프레독신 유래된 펩티드 변이체 인코딩 변이체 DNA를 산출할 수 있다. 이에 더하여, 쿠프레독신의 구조적 등가물인 쿠프레독신 유래된 펩티드를 인코딩하는 뉴클레오티드는 당분야에 공지된 방법으로 합성될 수 있다. 더 나아가, 변형된 쿠프레독신 유래된 펩티드인 단백질 분자는 당분야에 공지된 방법으로 합성될 수 있다.
쿠프레독신 침입 도메인 및 화물 화합물에 연결된 쿠프레독신 침입 도메인의 복합체를 코딩하는 핵산
다른 측면에서, 본 발명에서는 본 발명의 변형된 쿠프레독신 유래된 펩티드를 인코딩하는 핵산 분자를 제시한다. 이러한 핵산 분자는 당분야에 공지된 기술의 조합으로 제조될 수 있다. 가령, 변형된 쿠프레독신 유래된 펩티드에 대한 핵산 서열은 화학적 합성 또는 클로닝에 의해 개별적으로 제조될 수 있다.
변형된 쿠프레독신 유래된 펩티드를 함유하는 제약학적 조성물
변형된 쿠프레독신 유래된 펩티드를 함유하는 제약학적 조성물은 임의의 통상적인 방식, 예를 들면, 통상적인 혼합, 분해, 과립화, 당의정-만들기, 에멀젼화, 캡슐화, 포획, 또는 냉동 건조 과정으로 제조될 수 있다. 이러한 변형된 쿠프레독신 유래된 펩티드는 당분야에 공지된 제약학적으로 허용되는 담체와 용이하게 혼합될 수 있다. 이들 담체는 정제, 알약, 당의정, 캡슐, 액체, 겔, 시럽, 슬러리, 현탁액 등으로의 제조를 가능하게 한다. 적절한 부형제에는 예로써, 충전제와 셀룰로오스 제조물이 포함될 수 있다. 다른 부형제에는 예로써, 향료, 착색제, 디태크피어(detackifier), 농후제(thickness) 및 다른 허용되는 첨가제, 어쥬번트 또는 결합제가 포함될 수 있다.
이들 조성물은 예로써, 암의 치료 또는 진단, 부적절한 혈관신생의 치료, HIV 및/또는 말라리아에 의한 감염, 에프린-신호전달에 관련된 장애의 치료에 이용될 수 있다. 이들 조성물은 환자가 고통받는 장애를 예방하거나 치료할 만큼 충분한 양으로 투여될 수 있다. 전형적으로, 환자 생물체는 포유동물, 예를 들면, 인간 또는 동물이다.
쿠프레독신 침입 도메인을 함유하는 조성물의 투여
변형된 쿠프레독신 유래된 펩티드를 함유하는 조성물은 임의의 적절한 경로에 의해, 예를 들면, 경구, 협측, 흡입, 설하, 직장, 질, 경요도(transurethral), 비강, 국소, 경피, 또는 비경구(정맥내, 근육내, 피하, 관상동맥내 포함) 투여에 의해 투여될 수 있다. 이들 조성물 및 이들의 제약학적 제제는 의도된 목적을 달성하는 효과량으로 투여될 수 있다. 장애로 고통받는 환자를 치료하기 위하여 투여될 때, 조성물은 치료 효과량으로 투여된다. "치료 효과량"은 치료되는 개체에서 특정한 장애의 발생을 예방하고, 또는 이러한 장애의 기존 증상을 완화시키는데 효과적인 양이다. 치료 효과량의 결정은 당업자의 능력 범위 내에 속한다.
다양한 구체예에서, 조성물은 담체와 부형제(완충제, 탄수화물, 만니톨, 단백질, 폴리펩티드 또는 아미노산(가령, 글리신), 항산화제, 세균발육 저해제, 킬레이트화제, 현탁제, 농후제 및/또는 보존제 포함), 물, 오일, 염수 용액, 수성 덱스트로스와 글리세롤 용액, 약리학적 조건을 근사하기 위하여 요구되는 다른 제약학적으로 허용되는 보조 물질(가령, 완충제, 긴장도 조절제(tonicity adjusting agent), 적심제(wetting agent) 등)을 함유한다. 당업자에게 공지된 임의의 담체가 본 발명의 조성물을 투여하는데 이용될 수 있긴 하지만, 담체의 유형은 투여 방식에 따라 달라질 것이다. 화합물은 널리 공지된 기술을 이용하여 리포좀 내에 피포될 수도 있다. 생물분해성 마이크로스피어 역시 본 발명의 제약학적 조성물에 대한 담체로서 이용될 수 있다. 적절한 생물분해성 마이크로스피어는 예로써, U.S. Patent No. 4,897,268; 5,075,109; 5,928,647; 5,811,128; 5,820,883; 5,853,763; 5,814,344; 5,942,252에서 기술된다. 본 명세서에서, "화합물"에는 본 발명의 펩티드, 아미노산 서열, 화물 화합물과 복합체가 포함된다.
본 발명의 조성물은 널리 공지된 통상적인 멸균 기술로 멸균되거나, 또는 멸균 여과될 수 있다. 생성된 수용액은 원상태로 포장되거나, 또는 냉동 건조되는데, 이러한 냉동 건조된 제조물은 투여에 앞서 무균 용액과 혼합된다.
본 발명의 조성물은 주사(가령, 피내, 피하, 근육내, 복강내 등), 흡입, 국소 투여, 좌약, 경피 패치 또는 경구를 비롯한 다양한 방식으로 투여될 수 있다.
주사로 투여되는 경우에, 조성물은 수용액, 바람직하게는, 생리 적합성 완충제, 예를 들면, Hanks 용액, 링거액, 또는 생리 식염수 내에서 제조된다. 용액은 제제 약물(formulatory agent), 예를 들면, 현탁제, 안정화제 및/또는 분산제를 함유할 수 있다. 대안으로, 조성물은 사용에 앞서, 적절한 운반제, 예를 들면, 발열원-없는 무균수로 구성(constitution)을 위한 분말 형태로 존재한다.
흡입으로 투여되는 경우에, 조성물은 적절한 추진제(propellant), 예를 들면, 디클로로디플루오르메탄, 트리클로로플루오르메탄, 이산화탄소 또는 다른 적절한 가스를 이용한, 가압된 팩 또는 분무기로부터 에어로졸 스프레이의 형태로 전달된다. 가압된 에어로졸의 경우에, 투약 단위(dosage unit)는 정량을 전달하는 밸브를 제공함으로써 결정될 수 있다. 예로써, 흡입기 또는 취입기에 이용되는 젤라틴의 캡슐과 카트리지는 단백질 및 적절한 분말 기부(base), 예를 들면, 락토오스 또는 전분의 분말 혼합물을 함유하도록 제조된다.
국소 투여되는 경우에, 조성물은 당분야에 널리 공지된 바와 같이, 용액, 겔, 연고, 크림, 젤리, 현탁액 등으로 제조된다. 일부 구체예에서, 투여는 경피 패치에 의해 달성된다. 좌약(가령, 직장 또는 질)으로 투여되는 경우에, 조성물은 통상적인 좌약 기부(suppository base)를 함유하는 조성물 형태로 제조될 수도 있다.
경구 투여되는 경우에, 조성물은 당분야에 널리 공지된 제약학적으로 허용되는 담체와의 조합으로 용이하게 제조될 수 있다. 고형 담체, 예를 들면, 만니톨, 락토오스, 스테아르산마그네슘 등이 이용된다; 이들 담체는 이러한 케모탁신(chemotaxin)이 치료되는 개체에 의한 경구 섭취용으로 정제, 알약, 당의정, 캡슐, 액체, 겔, 시럽, 슬러리, 현탁액 등으로 제조될 수 있도록 한다. 경구 고형 제제, 예를 들면, 분말, 캡슐과 정제에 적합한 부형제에는 충전제(가령, 당), 셀룰로오스 제조물, 과립화제, 결합제 등이 포함된다.
당분야에 널리 공지된 다른 통상적인 담체에는 다가 담체, 예를 들면, 세균 캡슐 다당류, 덱스트란 또는 유전자 조작된 벡터 역시 포함된다. 이에 더하여, 이러한 조성물을 함유하는 서방 제제는 연장된 기간 동안 이러한 변형된 쿠프레독신 유래된 펩티드를 방출하는데, 이런 서방 제제가 없는 경우에 조성물은 치료 효과를 유도하거나 강화하기에 앞서, 예로써 프로테아제 및 간단한 가수분해에 의해 개체의 조직으로부터 제거되고 및/또는 분해된다.
정확한 제제, 투여 경로와 용량은 환자의 상태를 고려하여 담당 의사에 의해 결정된다. 용량과 휴지기는 치료 효과를 유지할 만큼 충분한 혈장 수준의 복합체를 제공하기 위하여 개별적으로 조정될 수 있다. 일반적으로, 원하는 조성물은 의도된 투여 경로와 표준 제약학적 관례에 따라 선택된 제약학적 담체와의 혼합물로 투여된다.
적절한 용량은 예로써, 이용된 변형된 진입 도메인을 포함하는 화합물, 호스트(host), 투여 방식과 치료되거나 진단되는 질환의 특성과 심각도에 따라 달라질 것이다. 하지만, 본 발명의 방법의 한 구체예에서, 인간에서 만족스런 결과는 체중 ㎏당 대략 0.01 내지 20 ㎎의 변형된 쿠프레독신 유래된 펩티드를 포함하는 화합물의 일일 용량(daily dosage)에서 달성되는 것으로 지정된다. 한 구체예에서, 인간에서 치료를 위한 지정된 일일 용량은 예로써, 1일 분량, 1주일 분량, 1개월 분량 및/또는 연속 투약(continuous dosing)으로 편의하게 투여되는 대략 0.7 ㎎ 내지 1400 ㎎ 범위의 변형된 쿠프레독신 유래된 펩티드를 포함하는 화합물이다. 1일 분량은 1일 1회 내지 12회 분리 투약될 수 있다. 대안으로, 분량은 2일마다, 3일마다, 4일마다, 5일마다, 6일마다, 1주일마다, 그리고 이와 유사하게 최대 31일 이상까지 하루씩 증가하여 투약될 수 있다. 투약은 정제, 패치, i.v. 투여 등을 비롯한 임의의 적용가능한 투약 형태(dosing form)를 이용한 연속적, 간헐적, 또는 단일 투약일 수 있다. 더욱 구체적으로, 조성물은 치료 효과량으로 투여된다. 특정 구체예에서, 치료 효과량은 체중 ㎏당 대략 0.01-20 ㎎/㎏이다. 특정 구체예에서, 용량 수준은 대략 10 ㎎/㎏/day, 대략 15 ㎎/㎏/day, 대략 20 ㎎/㎏/day, 대략 25 ㎎/㎏/day, 대략 30 ㎎/㎏/day, 대략 35 ㎎/㎏/day, 대략 40 ㎎/㎏/day, 대략 45 ㎎/㎏/day 또는 대략 50 ㎎/㎏/day이다.
변형된 쿠프레독신 유래된 펩티드를 포함하는 화합물을 환자에 도입하는 방법은 일부 구체예에서, 이러한 장애를 치료하는 것으로 알려진 다른 약물과 공동-투여(co-administration)이다. 이들 방법은 당분야에 널리 공지되어 있다. 특정 구체예에서, 변형된 쿠프레독신 유래된 펩티드를 포함하는 화합물은 암, HIV, 말라리아, 부적절한 혈관신생 및 에프린-신호전달에 관련된 장애를 치료하기 위한 다른 약물을 포함하거나 이러한 약물과 조합되는 칵테일(cocktail) 또는 공동-투약(co-dosing)의 일부이다. 이와 같은 많은 다른 화합물은 당업자에게 공지되어 있고, 참고문헌으로서 명시적으로 편입된 특허 출원에 의해 제공된다.
쿠프레독신 유래된 펩티드, 또는 쿠프레독신 유래된 펩티드와 화물 화합물을 결합하는 융합체 단백질을 인코딩하는 핵산 분자는 벡터 내로 삽입되고, 유전자 요법 벡터(gene therapy vector)로서 이용될 수 있다. 유전자 요법 벡터는 예로써, 정맥내 주입, 국소 투여(Nabel et al., U.S. Patent No. 5,328,470), 또는 정위적 주입(stereotactic injection)(Chen et al., Proc Natl Acad Sci USA 91:3054-3057 (1994))에 의해 개체에 전달될 수 있다. 유전자 요법 벡터의 제약학적 제조물은 수용가능 희석제를 함유하거나, 또는 이러한 유전자 전달 운반제가 끼워 넣어지는 지연 방출 매트릭스(slow release matrix)를 포함할 수 있다. 대안으로, 완전한 유전자 전달 벡터가 재조합 세포로부터 본래 상태로 생산될 수 있는 경우에(가령, 레트로바이러스 벡터), 제약학적 조제물은 이러한 유전자 전달 시스템(gene delivery system)을 생산하는 하나이상의 세포를 함유할 수 있다.
한 측면에서, 조성물은 DNA로서 전달되고, 이러한 복합체가 in situ에서 산출된다. 한 구체예에서, DNA는 예로써, Ulmer et al., Science, Vol.259, pp-1745-49(1993)에 기술되고 Cohen, Science, vol.259, pp-1691-92(1993)에서 검토된 바와 같이 "나신(naked)"이다. 나신 DNA의 흡수는 DNA를 담체, 예를 들면, 세포 내로 효과적으로 운반되는 생물분해성 비드 상에 코팅함으로써 증가될 수 있다. 이런 방법에서, DNA는 핵산 발현 시스템, 세균 발현 시스템과 바이러스 발현 시스템을 비롯한 당업자에게 공지된 다양한 전달 시스템 내에 존재한다. DNA를 이런 발현 시스템 내로 통합하는 기술은 당업자에게 널리 공지되어 있다(참조: WO90/11092, WO93/24640, WO93/17706, U.S. Pat. No. 5,736,524).
생물체로부터 생물체로 유전 물질을 이동시키는데 사용되는 벡터는 크게 2가지 부류로 구분될 수 있다: 클로닝 벡터는 적합한 숙주 세포 내에서 증식에 필수적이고 외래 DNA가 삽입될 수 있는 영역을 보유하는 복제 플라스미드 또는 파지이다; 외래 DNA는 벡터의 구성요소인 것처럼 복제되고 증식된다. 발현 벡터(가령, 플라스미드, 효모 또는 동물 바이러스 게놈)는 외래 DNA, 예를 들면, 상기 조성물의 DNA를 전사하고 번역하기 위하여 숙주 세포 또는 조직 내로 외래 유전 물질을 도입하는데 이용된다. 발현 벡터에서, 도입된 DNA는 삽입된 DNA를 전사하도록 숙주 세포에 신호하는 프로모터와 같은 요소에 작동가능하게 연결된다. 특정 인자에 대응하여 유전자 전사를 조절하는 유도성 프로모터와 같은 일부 프로모터가 특히 유용하다. 조성물 폴리뉴클레오티드를 유도성 프로모터에 작동가능하게 연결하면, 본 발명의 변형된 쿠프레독신 유래된 펩티드의 발현을 조절할 수 있다. 고전적인 유도성 프로모터의 실례는 α-인터페론, 열 충격, 중금속 이온 및 스테로이드, 예를 들면, 글루코코르티코이드(Kaufman, Methos Enzymol. 185:487-511 (1990))와 테트라사이클린에 반응하는 프로모터이다. 다른 바람직한 유도성 프로모터는 이러한 구조체가 도입되는 세포에 내인성이 아니지만 유도 인자(induction agent)가 외부로부터 공급되면 이들 세포에서 반응하는 프로모터이다. 일반적으로, 유용한 발현 벡터는 주로 플라스미드이다. 하지만, 다른 형태의 발현 벡터, 예를 들면, 바이러스 벡터(가령, 복제 결함성 레트로바이러스, 아데노바이러스와 아데노-연관된 바이러스) 역시 고려된다.
벡터 선택은 이용되는 생물체 또는 세포 및 벡터의 원하는 목적에 좌우된다. 일반적으로, 벡터는 신호 서열, 복제 기점, 마커 유전자, 인헨서 요소, 프로모터와 전사 종결 서열을 포함한다.
변형된 쿠프레독신 유래된 펩티드를 포함하는 키트
한 측면에서, 본 발명에서는 포장 또는 용기 내에 (1) 변형된 쿠프레독신 유래된 펩티드를 함유하는 반응물; (2) 제약학적으로 허용되는 어쥬번트 또는 부형제를 함유하는 반응물; (3) 투여용 운반기(vehicle), 예를 들면, 주사기; (4) 투약을 위한 사용설명서 중에서 한가지이상을 포함하는 키트를 제시한다. 구성요소 (1)-(4) 중에서 2가지 이상이 동일 포장 또는 용기 내에서 발견되는 구체예 역시 고려된다.
키트가 공급되는 경우에, 조성물의 서로 다른 구성요소는 별개의 용기 내에 포장되고 사용 직전에 혼합될 수 있다. 이들 구성요소의 이와 같은 개별 포장은 활성 구성요소의 기능 상실 없이 장기적인 저장을 가능하게 한다.
키트에 포함되는 반응물은 일정한 용기에 담아 공급함으로써, 서로 다른 구성요소의 수명이 보존되고 용기 재료에 의해 흡수되거나 변화되지 않도록 한다. 가령, 밀봉된 유리 앰풀은 냉동 건조된 폴리펩티드 또는 폴리뉴클레오티드, 또는 중성의 비-활성 가스, 예를 들면, 질소 하에 포장된 완충제를 포함한다. 앰풀은 임의의 적절한 재료, 예를 들면, 유리, 유기 중합체(가령, 폴리카보네이트, 폴리스트렌 등), 세라믹, 금속, 또는 유사한 반응물을 유지시키는데 전형적으로 이용되는 임의의 다른 물질로 구성된다. 적절한 용기의 다른 실례는 앰풀과 유사한 물질로부터 제조되는 단순한 병 및 알루미늄이나 합금과 같은 박을 입힌 내부를 보유하는 덮개이다. 다른 용기에는 검사 튜브, 바이알, 플라스크, 병, 주사기 등이 포함된다. 용기는 무균 접근 포트(access port), 예를 들면, 피하 주사 바늘이 관통할 수 있는 마개가 달린 병을 보유한다. 다른 용기는 용이하게 제거가능하고 제거 이후에 구성요소들이 혼합될 수 있도록 하는 막에 의해 분리되는 2개의 구획(compartment)을 보유한다. 제거가능 막은 유리, 플라스틱, 고무 등이다. 키트에는 사용설명서 역시 제공될 수 있다. 사용설명서는 종이 또는 다른 기질에 인쇄되고 및/또는 전자-판독가능 매체, 예를 들면, 플로피 디스크, CD-ROM, DVD-ROM, Zip 디스크, 비디오테이프, 오디오테이프, 플래시 메모리 장치 등으로 제공될 수 있다. 상세한 사용설명서는 키트에 물리적으로 부착되지 않을 수도 있다; 대신에, 사용자는 이러한 키트의 제조업체 또는 유통업체에 의해 특정된 인터넷 웹 사이트를 안내받거나, 또는 사용설명서를 전자 메일로서 제공받을 수도 있다.
본 발명의 더욱 완전한 이해는 아래의 구체적인 실시예를 참조함으로써 달성될 수 있다. 이들 실시예는 예시의 목적으로만 기술되고, 본 발명의 범위를 한정하지 않는다. 형태에서 변화 및 등가물의 치환은 편법으로 간주된다. 본 명세서에서 특정한 용어가 이용되고 있긴 하지만, 이들 용어는 설명을 목적으로 하고 본 발명을 제한하지 않는다. 본 발명의 기술적 사상과 범주를 벗어나지 않는 본 발명의 개변이 가능하고, 따라서, 본 발명은 첨부된 특허청구범위에 의해서만 한정된다.
실시예 1 - In vivo 이종이식된 종양 모형과 트래피킹 ( trafficking ) 실험
시간의 추이 동안 생쥐의 체내에서 p18(SEQ ID NO: 14)의 분포를 결정하기 위하여, Mel-2 이종이식편을 갖는 무흉선 생쥐에서 영상 연구를 수행하였다. 암컷 누드 생쥐는 1 x 106 UISO-Mel-2 세포를 옆구리에 피하 주입하였다. 종양이 0.5 ㎜(3개의 직경 크기 중에서 하나)의 크기로 성장하면, 표지된 p18로 연구를 시작하였다. p18을 표지하기 위하여, p18은 연속적으로 교반하면서, 4℃에서 2시간 동안 IRDye® 800CW NHS Ester 적외선 염료(LI-COR Biosciences, Lincoln, Nebraska)와 함께 항온 처리하였다. 표지된 펩티드는 Slide-A-Lyzer® Dialysis Cassette 내에서 최소 48시간 동안 PBS에 대한 투석(dialysis)으로, 결합되지 않은 염료로부터 분리하였다.
100 ㎕ 무균 PBS(phosphate buffered saline)에 담긴 125 ㎍/생쥐의 IRDye® 표지된 p18(SEQ ID NO: 14)을 정맥내 주입하고, 생쥐는 Odyssey® Infrared Imaging System을 이용하여 종양과 장기 내에서 표지된 염료의 탐지를 위하여 매일 스캔하였다. 피하 종양을 탐지하기 위하여 1 내지 1.5 ㎜의 깊이에서 고해상도 스캔을 촬영하였다. 800 ㎚ 채널에서 기록된 영상(녹색)은 특이적인 신호를 나타내고, 700 ㎚ 채널에서 기록된 영상(적색)은 배경을 나타낸다.
첫 번째 실험에서, 0.5 ㎜ Mel-2 종양을 보유하는 생쥐는 IRDye®의 국지화(localization)를 결정하기 위하여 최대 16일 동안 스캔하였다. 도 1. 두 번째 실험에서, 0.5 ㎜ Mel-2 종양을 보유하는 생쥐는 125 ㎍/생쥐의 IRDye® 표지된 p18을 i.v. 주입하고 120시간후 희생시켰다. 전신 스캔을 촬영하고, 장기와 종양을 절제하고 스캔하여 IRDye®의 국지화를 결정하였다. 절제(excision)후 장기와 단면(cross section)의 고해상도 스캔을 0.1 내지 0.5 ㎜의 깊이에서 촬영하였다. 도 2. 세 번째 실험에서, 생쥐는 Mel-2 세포를 주입하고, 이들 종양이 3주 동안 성장하도록 하였다. 이후, 생쥐는 125 ㎍/생쥐의 IRDye® 표지된 p18을 주입하고, 48시간후, 희생시키고 스캔하여 IRDye®의 국지화를 결정하였다.
이들 실험에서는 IRDye® 표지된 p18이 생쥐 내로 주입후 5시간 만에 종양과 신장으로 국지화된다는 것을 지시한다(도 1 참조). 신장에 IRDye-p18 복합체가 축적되는데, 이는 p18이 주로, 신장을 통한 배출에 의해 생쥐의 혈류로부터 제거된다는 것을 암시한다(도 2와 도 3 참조).
실시예 2 - 변형된 쿠프레독신 유래된 펩티드로 암 환자의 치료
PEG화된 p28(SEQ ID NO: 13) 융합체(연구 약물)의 I/II기 임상 시험이 암 환자에게서 실시된다. 구체적으로, 녹농균(Pseudomonas aeruginosa)으로부터 p28이 PEG화에 의해 변형된다.
현재 가용한 FDA-승인된 화학치료제(chemotherapeutic drug)와 섭생(regimen)에 의한 적절한 치료 이후에 임상적, 방사선사진적(radiographic) 진행 또는 재발을 나타내는 유방암, 결장암과 흑색종이 조직학적으로 검증된 49명의 성인 환자가 연구 약물을 투여하는 전향적 공개 연구(open-label prospective study)에 참여한다. 본 연구에 참여에 유자격한 모든 환자는 화학요법 섭생(chemotherapy regimen)의 승인된 과정의 완결후 측정가능 종양의 증가하는 체적을 나타낸다. 지속적인 전이 침착물(metastatic deposit) 및/또는 크기 또는 체적에서 지속적인 증가의 증거가 조직학적으로 확립되어야 한다. 이러한 조직학적 증거는 세침 흡인(fine needle aspiration, FNA) 생검에 의해 획득될 수 있다.
치료 프로그램(treatment program)은 Institutional Review Board of the University of Illinois(Chicago)와 FDA에 따라서, 모든 환자로부터 서면 동의서(informed consent)를 받은 이후에 실시된다. 이들 환자는 다른 악성 종양, 이전 악성 종양의 병력, 혈액 이상(blood dyscrasias), 인슐린 의존성 당뇨병(insulin dependent diabetes) 또는 제안된 요법의 효과의 적절한 평가를 간섭할 수도 있는 다른 심각한 심혈관 질환(cardiovascular disease)과 같은 병발 질환(intercurrent illness)이 없다. 간 기능 연구(liver function study, LFT)를 비롯한 기준 혈액 작업(baseline blood work)(완전 혈구 측정[Complete Blood Count, CBC]과 혈청 화학(Serum Chemistry))이 치료 개시에 앞서 수행된다. 모든 유자격 환자는 임상 시험 기간 동안 임의의 암 화학요법을 받지 않아야 한다. 연구 약물은 12주 동안 연구 약물의 제약학적으로 허용되는 조합제의 매일 정맥내 주입으로 투여되고, 개체 는 용량 제한 독성(dose limiting toxicity)이 관찰된다. 10 ㎎/㎏/day로 시작하여 50 ㎎/㎏/day의 최대 용량(maximum dose)까지 5 ㎎/㎏/day씩 증가하는 7가지 용량 수준(dose level)이 존재한다. 각 용량 수준의 효능은 진전된 측적가능 암(유방암, 결장암과 흑색종)을 나타내는 7명의 환자에서 기록된다.
반응은 측정가능 종양을 2 차원(a와 b)에서 측정함으로써 평가된다. 1) 표적 전이 종양의 완전한 소멸은 완전 반응(complete response, CR)으로 간주된다; 2) 75% 감소는 우수한 부분적인 반응(partial response, PR)으로 간주된다; 3) 양호한 반응(good response, GR)은 치료후 크기에서 50% 감소이다. 4) 크기에서 25% 감소는 안정한 질환(stable disease, SD)으로 간주되고, 5) < 25%는 반응 없음(no response, NR)으로 간주된다. 질병의 진행을 나타내는 환자는 치료를 중단하고, 추가로 12주 동안 추적한다.
표적 전이 종양의 완전한 소멸과 크기 감소는 아주린 치료가 암을 치료하는데 효과적임을 지시한다. PEG화된 p28 치료가 효과적이라는 다른 징후는 새로운 전이 종양의 출현 속도에서 감소 및 종양과 연관된 혈관신생에서 감소이다.
본 발명의 범위와 기술적 사상을 벗어나지 않는, 앞서 기술된 실시예와 시스템의 다양한 개변은 당업자에게 명백할 것이다. 본 발명이 특정 구체예와 관련하여 기술되긴 했지만, 본 발명은 이들 특정 구체예에 부당하게 한정되지 않는다. 실제로, 관련 분야의 당업자에게 명백한, 본 발명을 수행하기 위한 앞서 기술된 양식의 다양한 변형은 아래의 특허청구범위의 범위 내에 포섭된다.
SEQUENCE LISTING <110> DAS GUPTA, TAPAS CHAKRABARTY, ANANDA <120> MODIFICATIONS OF CUPREDOXIN DERIVED PEPTIDES AND METHODS OF USE THEREOF <130> 14PR-132881 <140> 11/853,497 <141> 2007-09-11 <150> 60/843,388 <151> 2006-09-11 <150> 11/244,105 <151> 2005-10-06 <150> 60/700,297 <151> 2005-07-19 <150> 60/680,500 <151> 2005-05-13 <150> 60/616,782 <151> 2004-10-07 <160> 3505 <170> PatentIn version 3.5 <210> 1 <211> 128 <212> PRT <213> Pseudomonas aeruginosa <400> 1 Ala Glu Cys Ser Val Asp Ile Gln Gly Asn Asp Gln Met Gln Phe Asn 1 5 10 15 Thr Asn Ala Ile Thr Val Asp Lys Ser Cys Lys Gln Phe Thr Val Asn 20 25 30 Leu Ser His Pro Gly Asn Leu Pro Lys Asn Val Met Gly His Asn Trp 35 40 45 Val Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met 50 55 60 Ala Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp Ser Arg Val 65 70 75 80 Ile Ala His Thr Lys Leu Ile Gly Ser Gly Glu Lys Asp Ser Val Thr 85 90 95 Phe Asp Val Ser Lys Leu Lys Glu Gly Glu Gln Tyr Met Phe Phe Cys 100 105 110 Thr Phe Pro Gly His Ser Ala Leu Met Lys Gly Thr Leu Thr Leu Lys 115 120 125 <210> 2 <211> 105 <212> PRT <213> Phormidium laminosum <400> 2 Glu Thr Phe Thr Val Lys Met Gly Ala Asp Ser Gly Leu Leu Gln Phe 1 5 10 15 Glu Pro Ala Asn Val Thr Val His Pro Gly Asp Thr Val Lys Trp Val 20 25 30 Asn Asn Lys Leu Pro Pro His Asn Ile Leu Phe Asp Asp Lys Gln Val 35 40 45 Pro Gly Ala Ser Lys Glu Leu Ala Asp Lys Leu Ser His Ser Gln Leu 50 55 60 Met Phe Ser Pro Gly Glu Ser Tyr Glu Ile Thr Phe Ser Ser Asp Phe 65 70 75 80 Pro Ala Gly Thr Tyr Thr Tyr Tyr Cys Ala Pro His Arg Gly Ala Gly 85 90 95 Met Val Gly Lys Ile Thr Val Glu Gly 100 105 <210> 3 <211> 155 <212> PRT <213> Thiobacillus ferrooxidans <400> 3 Gly Thr Leu Asp Thr Thr Trp Lys Glu Ala Thr Leu Pro Gln Val Lys 1 5 10 15 Ala Met Leu Glu Lys Asp Thr Gly Lys Val Ser Gly Asp Thr Val Thr 20 25 30 Tyr Ser Gly Lys Thr Val His Val Val Ala Ala Ala Val Leu Pro Gly 35 40 45 Phe Pro Phe Pro Ser Phe Glu Val His Asp Lys Lys Asn Pro Thr Leu 50 55 60 Glu Ile Pro Ala Gly Ala Thr Val Asp Val Thr Phe Ile Asn Thr Asn 65 70 75 80 Lys Gly Phe Gly His Ser Phe Asp Ile Thr Lys Lys Gly Pro Pro Tyr 85 90 95 Ala Val Met Pro Val Ile Asp Pro Ile Val Ala Gly Thr Gly Phe Ser 100 105 110 Pro Val Pro Lys Asp Gly Lys Phe Gly Tyr Thr Asp Phe Thr Trp His 115 120 125 Pro Thr Ala Gly Thr Tyr Tyr Tyr Val Cys Gln Ile Pro Gly His Ala 130 135 140 Ala Thr Gly Met Phe Gly Lys Ile Val Val Lys 145 150 155 <210> 4 <211> 124 <212> PRT <213> Achromobacter cycloclastes <400> 4 Ala Asp Phe Glu Val His Met Leu Asn Lys Gly Lys Asp Gly Ala Met 1 5 10 15 Val Phe Glu Pro Ala Ser Leu Lys Val Ala Pro Gly Asp Thr Val Thr 20 25 30 Phe Ile Pro Thr Asp Lys Gly His Asn Val Glu Thr Ile Lys Gly Met 35 40 45 Ile Pro Asp Gly Ala Glu Ala Phe Lys Ser Lys Ile Asn Glu Asn Tyr 50 55 60 Lys Val Thr Phe Thr Ala Pro Gly Val Tyr Gly Val Lys Cys Thr Pro 65 70 75 80 His Tyr Gly Met Gly Met Val Gly Val Val Gln Val Gly Asp Ala Pro 85 90 95 Ala Asn Leu Glu Ala Val Lys Gly Ala Lys Asn Pro Lys Lys Ala Gln 100 105 110 Glu Arg Leu Asp Ala Ala Leu Ala Ala Leu Gly Asn 115 120 <210> 5 <211> 136 <212> PRT <213> Pseudomonas syringae <400> 5 Met Ala Ser Gly Gln Leu Leu Ala Ala Glu Cys Ser Ala Thr Val Asp 1 5 10 15 Ser Thr Asp Gln Met Met Tyr Asp Thr Lys Ala Ile Gln Ile Asp Lys 20 25 30 Ser Cys Lys Glu Phe Thr Leu Asn Leu Thr His Ser Gly Ser Leu Pro 35 40 45 Lys Asn Val Met Gly His Asn Trp Val Leu Ser Lys Lys Ala Asp Ala 50 55 60 Ser Ala Ile Thr Thr Asp Gly Met Ser Val Gly Ile Asp Lys Asp Tyr 65 70 75 80 Val Lys Pro Asp Asp Thr Arg Val Ile Ala His Thr Lys Ile Ile Gly 85 90 95 Ala Gly Glu Asn Asp Ser Val Thr Phe Asp Val Ser Lys Leu Asp Pro 100 105 110 Ala Glu Asp Tyr Gln Phe Phe Cys Thr Phe Pro Gly His Ile Ser Met 115 120 125 Met Lys Gly Ala Val Thr Leu Lys 130 135 <210> 6 <211> 183 <212> PRT <213> Neisseria gonorrhoeae <400> 6 Met Lys Ala Tyr Leu Ala Leu Ile Ser Ala Ala Val Ile Gly Leu Ala 1 5 10 15 Ala Cys Ser Gln Glu Pro Ala Ala Pro Ala Ala Glu Ala Thr Pro Ala 20 25 30 Gly Glu Ala Pro Ala Ser Glu Ala Pro Ala Ala Glu Ala Ala Pro Ala 35 40 45 Asp Ala Ala Glu Ala Pro Ala Ala Gly Asn Cys Ala Ala Thr Val Glu 50 55 60 Ser Asn Asp Asn Met Gln Phe Asn Thr Lys Asp Ile Gln Val Ser Lys 65 70 75 80 Ala Cys Lys Glu Phe Thr Ile Thr Leu Lys His Thr Gly Thr Gln Pro 85 90 95 Lys Ala Ser Met Gly His Asn Leu Val Ile Ala Lys Ala Glu Asp Met 100 105 110 Asp Gly Val Phe Lys Asp Gly Val Gly Ala Ala Asp Thr Asp Tyr Val 115 120 125 Lys Pro Asp Asp Ala Arg Val Val Ala His Thr Lys Leu Ile Gly Gly 130 135 140 Gly Glu Glu Ser Ser Leu Thr Leu Asp Pro Ala Lys Leu Ala Asp Gly 145 150 155 160 Asp Tyr Lys Phe Ala Cys Thr Phe Pro Gly His Gly Ala Leu Met Asn 165 170 175 Gly Lys Val Thr Leu Val Asp 180 <210> 7 <211> 183 <212> PRT <213> Neisseria meningitides <400> 7 Met Lys Ala Tyr Leu Ala Leu Ile Ser Ala Ala Val Ile Gly Leu Ala 1 5 10 15 Ala Cys Ser Gln Glu Pro Ala Ala Pro Ala Ala Glu Ala Thr Pro Ala 20 25 30 Ala Glu Ala Pro Ala Ser Glu Ala Pro Ala Ala Glu Ala Ala Pro Ala 35 40 45 Asp Ala Ala Glu Ala Pro Ala Ala Gly Asn Cys Ala Ala Thr Val Glu 50 55 60 Ser Asn Asp Asn Met Gln Phe Asn Thr Lys Asp Ile Gln Val Ser Lys 65 70 75 80 Ala Cys Lys Glu Phe Thr Ile Thr Leu Lys His Thr Gly Thr Gln Pro 85 90 95 Lys Thr Ser Met Gly His Asn Ile Val Ile Gly Lys Thr Glu Asp Met 100 105 110 Asp Gly Ile Phe Lys Asp Gly Val Gly Ala Ala Asp Thr Asp Tyr Val 115 120 125 Lys Pro Asp Asp Ala Arg Val Val Ala His Thr Lys Leu Ile Gly Gly 130 135 140 Gly Glu Glu Ser Ser Leu Thr Leu Asp Pro Ala Lys Leu Ala Asp Gly 145 150 155 160 Glu Tyr Lys Phe Ala Cys Thr Phe Pro Gly His Gly Ala Leu Met Asn 165 170 175 Gly Lys Val Thr Leu Val Asp 180 <210> 8 <211> 150 <212> PRT <213> Vibrio parahaemolyticus <400> 8 Met Ser Leu Arg Ile Leu Ala Ala Thr Leu Ala Leu Ala Gly Leu Ser 1 5 10 15 Phe Gly Ala Gln Ala Ser Ala Glu Cys Glu Val Ser Ile Asp Ala Asn 20 25 30 Asp Met Met Gln Phe Ser Thr Lys Thr Leu Ser Val Pro Ala Thr Cys 35 40 45 Lys Glu Val Thr Leu Thr Leu Asn His Thr Gly Lys Met Pro Ala Gln 50 55 60 Ser Met Gly His Asn Val Val Ile Ala Asp Thr Ala Asn Ile Gln Ala 65 70 75 80 Val Gly Thr Asp Gly Met Ser Ala Gly Ala Asp Asn Ser Tyr Val Lys 85 90 95 Pro Asp Asp Glu Arg Val Tyr Ala His Thr Lys Val Val Gly Gly Gly 100 105 110 Glu Ser Thr Ser Ile Thr Phe Ser Thr Glu Lys Met Thr Ala Gly Gly 115 120 125 Asp Tyr Ser Phe Phe Cys Ser Phe Pro Gly His Trp Ala Ile Met Gln 130 135 140 Gly Lys Phe Glu Phe Lys 145 150 <210> 9 <211> 129 <212> PRT <213> Bordetella bronchiseptica <400> 9 Ala Glu Cys Ser Val Asp Ile Ala Gly Thr Asp Gln Met Gln Phe Asp 1 5 10 15 Lys Lys Ala Ile Glu Val Ser Lys Ser Cys Lys Gln Phe Thr Val Asn 20 25 30 Leu Lys His Thr Gly Lys Leu Pro Arg Asn Val Met Gly His Asn Trp 35 40 45 Val Leu Thr Lys Thr Ala Asp Met Gln Ala Val Glu Lys Asp Gly Ile 50 55 60 Ala Ala Gly Leu Asp Asn Gln Tyr Leu Lys Ala Gly Asp Thr Arg Val 65 70 75 80 Leu Ala His Thr Lys Val Leu Gly Gly Gly Glu Ser Asp Ser Val Thr 85 90 95 Phe Asp Val Ala Lys Leu Ala Ala Gly Asp Asp Tyr Thr Phe Phe Cys 100 105 110 Ser Phe Pro Gly His Gly Ala Leu Met Lys Gly Thr Leu Lys Leu Val 115 120 125 Asp <210> 10 <211> 162 <212> PRT <213> Chloroflexus aurantiacus <400> 10 Met Lys Ile Thr Leu Arg Met Met Val Leu Ala Val Leu Thr Ala Met 1 5 10 15 Ala Met Val Leu Ala Ala Cys Gly Gly Gly Gly Ser Ser Gly Gly Ser 20 25 30 Thr Gly Gly Gly Ser Gly Ser Gly Pro Val Thr Ile Glu Ile Gly Ser 35 40 45 Lys Gly Glu Glu Leu Ala Phe Asp Lys Thr Glu Leu Thr Val Ser Ala 50 55 60 Gly Gln Thr Val Thr Ile Arg Phe Lys Asn Asn Ser Ala Val Gln Gln 65 70 75 80 His Asn Trp Ile Leu Val Lys Gly Gly Glu Ala Glu Ala Ala Asn Ile 85 90 95 Ala Asn Ala Gly Leu Ser Ala Gly Pro Ala Ala Asn Tyr Leu Pro Ala 100 105 110 Asp Lys Ser Asn Ile Ile Ala Glu Ser Pro Leu Ala Asn Gly Asn Glu 115 120 125 Thr Val Glu Val Thr Phe Thr Ala Pro Ala Ala Gly Thr Tyr Leu Tyr 130 135 140 Ile Cys Thr Val Pro Gly His Tyr Pro Leu Met Gln Gly Lys Leu Val 145 150 155 160 Val Asn <210> 11 <211> 140 <212> PRT <213> Chloroflexus aurantiacus <400> 11 Ala Ala Asn Ala Pro Gly Gly Ser Asn Val Val Asn Glu Thr Pro Ala 1 5 10 15 Gln Thr Val Glu Val Arg Ala Ala Pro Asp Ala Leu Ala Phe Ala Gln 20 25 30 Thr Ser Leu Ser Leu Pro Ala Asn Thr Val Val Arg Leu Asp Phe Val 35 40 45 Asn Gln Asn Asn Leu Gly Val Gln His Asn Trp Val Leu Val Asn Gly 50 55 60 Gly Asp Asp Val Ala Ala Ala Val Asn Thr Ala Ala Gln Asn Asn Ala 65 70 75 80 Asp Ala Leu Phe Val Pro Pro Pro Asp Thr Pro Asn Ala Leu Ala Trp 85 90 95 Thr Ala Met Leu Asn Ala Gly Glu Ser Gly Ser Val Thr Phe Arg Thr 100 105 110 Pro Ala Pro Gly Thr Tyr Leu Tyr Ile Cys Thr Phe Pro Gly His Tyr 115 120 125 Leu Ala Gly Met Lys Gly Thr Leu Thr Val Thr Pro 130 135 140 <210> 12 <211> 129 <212> PRT <213> Bordetella pertussis <400> 12 Ala Glu Cys Ser Val Asp Ile Ala Gly Thr Asp Gln Met Gln Phe Asp 1 5 10 15 Lys Lys Ala Ile Glu Val Ser Lys Ser Cys Lys Gln Phe Thr Val Asn 20 25 30 Leu Lys His Thr Gly Lys Leu Pro Arg Asn Val Met Gly His Asn Trp 35 40 45 Val Leu Thr Lys Thr Ala Asp Met Gln Ala Val Glu Lys Asp Gly Ile 50 55 60 Ala Ala Gly Leu Asp Asn Gln Tyr Leu Lys Ala Gly Asp Thr Arg Val 65 70 75 80 Leu Ala His Thr Lys Val Leu Gly Gly Gly Glu Ser Asp Ser Val Thr 85 90 95 Phe Asp Val Ala Lys Leu Ala Ala Gly Asp Asp Tyr Thr Phe Phe Cys 100 105 110 Ser Phe Pro Gly His Gly Ala Leu Met Lys Gly Thr Leu Lys Leu Val 115 120 125 Asp <210> 13 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 13 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 14 <211> 18 <212> PRT <213> Pseudomonas aeruginosa <400> 14 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly <210> 15 <211> 93 <212> PRT <213> Pseudomonas aeruginosa <400> 15 Pro Gly Asn Leu Pro Lys Asn Val Met Gly His Asn Trp Val Leu Ser 1 5 10 15 Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala Ser Gly 20 25 30 Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp Ser Arg Val Ile Ala His 35 40 45 Thr Lys Leu Ile Gly Ser Gly Glu Lys Asp Ser Val Thr Phe Asp Val 50 55 60 Ser Lys Leu Lys Glu Gly Glu Gln Tyr Met Phe Phe Cys Thr Phe Pro 65 70 75 80 Gly His Ser Ala Leu Met Lys Gly Thr Leu Thr Leu Lys 85 90 <210> 16 <211> 54 <212> PRT <213> Pseudomonas aeruginosa <400> 16 Pro Gly Asn Leu Pro Lys Asn Val Met Gly His Asn Trp Val Leu Ser 1 5 10 15 Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala Ser Gly 20 25 30 Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp Ser Arg Val Ile Ala His 35 40 45 Thr Lys Leu Ile Gly Ser 50 <210> 17 <211> 42 <212> PRT <213> Pseudomonas aeruginosa <400> 17 Pro Gly Asn Leu Pro Lys Asn Val Met Gly His Asn Trp Val Leu Ser 1 5 10 15 Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala Ser Gly 20 25 30 Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 35 40 <210> 18 <211> 15 <212> PRT <213> Pseudomonas aeruginosa <400> 18 Pro Gly Asn Leu Pro Lys Asn Val Met Gly His Asn Trp Val Leu 1 5 10 15 <210> 19 <211> 17 <212> PRT <213> Pseudomonas aeruginosa <400> 19 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser <210> 20 <211> 11 <212> PRT <213> Pseudomonas aeruginosa <400> 20 Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 1 5 10 <210> 21 <211> 33 <212> PRT <213> Chloroflexus aurantiacus <400> 21 His Asn Trp Val Leu Val Asn Gly Gly Asp Asp Val Ala Ala Ala Val 1 5 10 15 Asn Thr Ala Ala Gln Asn Asn Ala Asp Ala Leu Phe Val Pro Pro Pro 20 25 30 Asp <210> 22 <211> 28 <212> PRT <213> Bordetella pertussis <400> 22 Leu Thr Lys Thr Ala Asp Met Gln Ala Val Glu Lys Asp Gly Ile Ala 1 5 10 15 Ala Gly Leu Asp Asn Gln Tyr Leu Lys Ala Gly Asp 20 25 <210> 23 <211> 27 <212> PRT <213> Neisseria meningitidis <400> 23 Ile Ala Lys Ala Glu Asp Met Asp Gly Val Phe Lys Asp Gly Val Gly 1 5 10 15 Ala Ala Asp Thr Asp Tyr Val Lys Pro Asp Asp 20 25 <210> 24 <211> 21 <212> PRT <213> Pseudomonas aeruginosa <400> 24 Glu Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala Ser Gly 1 5 10 15 Leu Asp Lys Asp Tyr 20 <210> 25 <211> 15 <212> PRT <213> Pseudomonas aeruginosa <400> 25 Glu Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala Ser 1 5 10 15 <210> 26 <211> 27 <212> PRT <213> Pseudomonas aeruginosa <400> 26 Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala Ser 1 5 10 15 Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 27 <211> 27 <212> PRT <213> Pseudomonas syringae <400> 27 Ser Lys Lys Ala Asp Ala Ser Ala Ile Thr Thr Asp Gly Met Ser Val 1 5 10 15 Gly Ile Asp Lys Asp Tyr Val Lys Pro Asp Asp 20 25 <210> 28 <211> 27 <212> PRT <213> Vibrio parahaemolyticus <400> 28 Ala Asp Thr Ala Asn Ile Gln Ala Val Gly Thr Asp Gly Met Ser Ala 1 5 10 15 Gly Ala Asp Asn Ser Tyr Val Lys Pro Asp Asp 20 25 <210> 29 <211> 27 <212> PRT <213> Bordetella bronchiseptica <400> 29 Thr Lys Thr Ala Asp Met Gln Ala Val Glu Lys Asp Gly Ile Ala Ala 1 5 10 15 Gly Leu Asp Asn Gln Tyr Leu Lys Ala Gly Asp 20 25 <210> 30 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 30 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 31 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 31 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 32 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 32 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 33 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 33 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 34 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 34 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 35 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 35 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 36 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 36 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 37 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 37 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 38 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 38 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 39 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 39 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 40 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 40 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 41 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 41 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 42 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 42 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 43 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 43 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 44 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 44 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 45 <211> 28 <212> PRT <213> Pseudomonas aeruginosa <400> 45 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 46 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <221> MOD_RES <222> (3)..(7) <223> Any amino acid <220> <221> MOD_RES <222> (9)..(10) <223> Any amino acid <220> <221> MOD_RES <222> (12)..(12) <223> Any amino acid <220> <221> MOD_RES <222> (14)..(15) <223> Any amino acid <400> 46 Asp Gly Xaa Xaa Xaa Xaa Xaa Asp Xaa Xaa Tyr Xaa Lys Xaa Xaa Asp 1 5 10 15 <210> 47 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <221> MOD_RES <222> (3)..(6) <223> Any amino acid <220> <221> MOD_RES <222> (8)..(9) <223> Any amino acid <220> <221> MOD_RES <222> (11)..(11) <223> Any amino acid <220> <221> MOD_RES <222> (13)..(14) <223> Any amino acid <400> 47 Asp Gly Xaa Xaa Xaa Xaa Asp Xaa Xaa Tyr Xaa Lys Xaa Xaa Asp 1 5 10 15 <210> 48 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus may or may not be acetylated <220> <221> MOD_RES <222> (3)..(3) <223> Thr or Trp <220> <221> MOD_RES <222> (7)..(7) <223> Met, Leu, or Val <220> <221> MOD_RES <222> (8)..(8) <223> Gln or Trp <220> <221> MOD_RES <222> (9)..(9) <223> Gly or Ala <220> <221> MOD_RES <222> (12)..(12) <223> Thr or Trp <220> <221> MOD_RES <222> (14)..(14) <223> Gly, Thr, or Trp <220> <221> MOD_RES <222> (15)..(15) <223> Met, Leu, or Val <220> <223> C-terminus may or may not be amidated <400> 48 Leu Ser Xaa Ala Ala Asp Xaa Xaa Xaa Val Val Xaa Asp Xaa Xaa Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 49 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus may or may not be acetylated <220> <221> MOD_RES <222> (14)..(14) <223> Met, Leu, or Val <220> <221> MOD_RES <222> (15)..(15) <223> Gly, Thr, or Trp <220> <221> MOD_RES <222> (17)..(17) <223> Thr or Trp <220> <221> MOD_RES <222> (20)..(20) <223> Gly or Ala <220> <221> MOD_RES <222> (21)..(21) <223> Gln or Trp <220> <221> MOD_RES <222> (22)..(22) <223> Met, Leu, or Val <220> <221> MOD_RES <222> (26)..(26) <223> Thr or Trp <220> <223> C-terminus may or may not be amidated <400> 49 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Xaa Xaa Asp 1 5 10 15 Xaa Val Val Xaa Xaa Xaa Asp Ala Ala Xaa Ser Leu 20 25 <210> 50 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 50 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 51 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 51 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 52 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 52 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 53 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 53 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 54 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 54 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 55 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 55 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 56 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 56 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 57 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 57 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 58 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 58 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 59 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 59 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 60 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 60 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 61 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 61 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 62 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 62 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 63 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 63 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 64 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 64 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 65 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 65 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 66 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 66 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 67 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 67 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 68 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 68 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 69 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 69 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 70 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 70 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 71 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 71 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 72 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 72 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 73 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 73 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 74 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 74 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 75 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 75 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 76 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 76 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 77 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 77 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 78 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 78 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 79 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 79 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 80 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 80 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 81 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 81 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 82 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 82 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 83 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 83 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 84 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 84 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 85 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 85 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 86 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 86 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 87 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 87 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 88 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 88 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 89 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 89 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 90 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 90 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 91 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 91 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 92 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 92 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 93 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 93 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 94 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 94 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 95 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 95 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 96 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 96 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 97 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 97 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 98 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 98 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 99 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 99 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 100 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 100 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 101 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 101 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 102 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 102 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 103 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 103 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 104 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 104 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 105 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 105 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 106 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 106 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 107 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 107 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 108 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 108 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 109 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 109 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 110 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 110 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 111 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 111 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 112 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 112 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 113 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 113 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 114 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 114 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 115 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 115 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 116 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 116 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 117 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 117 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 118 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 118 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 119 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 119 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 120 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 120 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 121 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 121 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 122 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 122 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 123 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 123 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 124 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 124 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 125 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 125 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 126 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 126 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 127 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 127 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 128 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 128 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 129 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 129 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 130 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 130 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 131 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 131 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 132 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 132 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 133 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 133 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 134 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 134 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 135 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 135 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 136 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 136 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 137 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 137 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 138 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 138 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 139 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 139 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 140 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 140 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 141 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 141 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 142 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 142 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 143 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 143 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 144 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 144 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 145 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 145 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 146 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 146 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 147 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 147 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 148 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 148 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 149 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 149 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 150 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 150 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 151 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 151 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 152 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 152 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 153 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 153 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 154 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 154 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 155 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 155 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 156 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 156 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 157 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 157 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 158 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 158 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 159 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 159 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 160 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 160 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 161 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 161 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 162 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 162 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 163 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 163 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 164 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 164 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 165 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 165 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 166 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 166 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 167 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 167 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 168 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 168 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 169 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 169 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 170 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 170 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 171 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 171 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 172 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 172 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 173 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 173 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 174 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 174 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 175 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 175 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 176 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 176 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 177 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 177 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 178 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 178 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 179 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 179 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 180 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 180 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 181 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 181 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 182 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 182 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 183 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 183 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 184 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 184 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 185 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 185 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 186 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 186 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 187 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 187 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 188 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 188 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 189 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 189 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 190 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 190 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 191 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 191 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 192 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 192 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 193 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 193 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 194 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 194 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 195 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 195 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 196 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 196 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 197 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 197 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 198 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 198 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 199 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 199 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 200 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 200 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 201 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 201 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 202 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 202 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 203 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 203 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 204 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 204 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 205 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 205 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 206 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 206 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 207 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 207 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 208 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 208 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 209 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 209 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 210 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 210 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 211 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 211 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 212 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 212 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 213 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 213 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 214 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 214 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 215 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 215 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 216 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 216 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 217 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 217 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 218 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 218 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 219 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 219 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 220 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 220 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 221 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 221 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 222 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 222 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 223 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 223 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 224 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 224 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 225 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 225 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 226 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 226 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 227 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 227 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 228 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 228 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 229 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 229 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 230 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 230 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 231 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 231 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 232 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 232 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 233 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 233 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 234 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 234 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 235 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 235 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 236 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 236 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 237 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 237 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 238 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 238 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 239 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 239 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 240 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 240 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 241 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 241 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 242 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 242 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 243 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 243 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 244 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 244 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 245 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 245 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 246 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 246 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 247 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 247 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 248 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 248 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 249 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 249 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 250 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 250 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 251 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 251 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 252 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 252 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 253 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 253 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 254 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 254 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 255 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 255 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 256 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 256 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 257 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 257 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 258 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 258 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 259 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 259 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 260 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 260 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 261 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 261 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 262 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 262 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 263 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 263 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 264 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 264 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 265 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 265 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 266 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 266 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 267 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 267 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 268 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 268 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 269 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 269 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 270 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 270 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 271 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 271 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 272 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 272 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 273 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 273 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 274 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 274 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 275 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 275 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 276 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 276 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 277 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 277 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 278 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 278 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 279 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 279 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 280 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 280 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 281 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 281 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 282 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 282 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 283 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 283 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 284 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 284 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 285 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 285 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 286 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 286 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 287 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 287 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 288 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 288 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 289 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 289 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 290 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 290 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 291 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 291 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 292 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 292 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 293 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 293 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 294 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 294 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 295 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 295 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 296 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 296 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 297 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 297 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 298 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 298 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 299 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 299 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 300 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 300 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 301 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 301 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 302 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 302 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 303 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 303 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 304 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 304 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 305 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 305 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 306 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 306 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 307 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 307 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 308 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 308 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 309 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 309 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 310 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 310 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 311 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 311 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 312 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 312 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 313 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 313 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 314 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 314 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 315 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 315 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 316 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 316 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 317 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 317 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 318 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 318 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 319 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 319 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 320 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 320 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 321 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 321 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 322 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 322 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 323 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 323 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 324 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 324 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 325 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 325 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 326 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 326 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 327 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 327 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 328 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 328 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 329 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 329 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 330 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 330 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 331 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 331 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 332 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 332 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 333 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 333 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 334 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 334 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 335 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 335 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 336 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 336 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 337 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 337 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 338 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 338 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 339 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 339 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 340 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 340 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 341 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 341 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 342 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 342 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 343 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 343 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 344 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 344 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 345 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 345 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 346 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 346 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 347 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 347 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 348 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 348 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 349 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 349 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 350 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 350 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 351 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 351 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 352 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 352 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 353 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 353 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 354 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 354 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 355 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 355 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 356 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 356 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 357 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 357 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 358 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 358 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 359 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 359 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 360 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 360 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 361 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 361 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 362 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 362 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 363 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 363 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 364 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 364 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 365 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 365 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 366 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 366 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 367 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 367 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 368 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 368 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 369 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 369 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 370 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 370 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 371 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 371 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 372 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 372 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 373 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 373 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 374 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 374 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 375 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 375 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 376 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 376 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 377 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 377 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 378 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 378 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 379 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 379 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 380 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 380 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 381 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 381 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 382 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 382 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 383 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 383 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 384 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 384 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 385 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 385 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 386 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 386 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 387 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 387 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 388 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 388 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 389 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 389 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 390 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 390 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 391 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 391 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 392 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 392 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 393 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 393 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 394 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 394 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 395 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 395 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 396 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 396 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 397 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 397 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 398 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 398 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 399 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 399 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 400 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 400 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 401 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 401 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 402 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 402 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 403 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 403 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 404 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 404 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 405 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 405 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 406 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 406 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 407 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 407 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 408 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 408 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 409 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 409 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 410 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 410 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 411 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 411 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 412 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 412 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 413 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 413 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 414 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 414 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 415 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 415 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 416 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 416 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 417 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 417 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 418 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 418 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 419 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 419 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 420 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 420 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 421 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 421 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 422 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 422 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 423 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 423 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 424 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 424 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 425 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 425 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 426 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 426 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 427 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 427 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 428 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 428 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 429 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 429 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 430 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 430 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 431 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 431 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 432 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 432 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 433 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 433 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 434 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 434 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 435 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 435 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 436 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 436 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 437 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 437 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 438 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 438 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 439 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 439 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 440 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 440 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 441 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 441 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 442 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 442 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 443 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 443 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 444 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 444 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 445 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 445 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 446 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 446 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 447 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 447 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 448 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 448 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 449 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 449 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 450 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 450 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 451 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 451 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 452 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 452 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 453 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 453 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 454 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 454 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 455 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 455 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 456 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 456 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 457 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 457 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 458 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 458 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 459 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 459 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 460 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 460 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 461 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 461 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 462 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 462 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 463 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 463 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 464 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 464 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 465 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 465 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 466 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 466 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 467 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 467 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 468 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 468 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 469 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 469 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 470 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 470 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 471 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 471 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 472 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 472 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 473 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 473 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 474 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 474 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 475 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 475 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 476 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 476 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 477 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 477 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 478 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 478 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 479 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 479 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 480 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 480 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 481 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 481 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 482 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 482 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 483 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 483 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 484 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 484 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 485 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 485 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 486 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 486 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 487 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 487 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 488 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 488 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 489 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 489 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 490 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 490 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 491 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 491 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 492 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 492 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 493 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 493 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 494 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 494 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 495 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 495 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 496 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 496 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 497 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 497 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 498 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 498 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 499 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 499 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 500 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 500 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 501 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 501 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 502 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 502 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 503 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 503 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 504 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 504 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 505 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 505 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 506 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 506 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 507 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 507 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 508 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 508 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 509 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 509 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 510 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 510 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 511 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 511 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 512 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 512 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 513 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 513 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 514 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 514 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 515 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 515 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 516 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 516 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 517 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 517 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 518 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 518 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 519 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 519 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 520 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 520 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 521 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 521 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 522 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 522 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 523 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 523 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 524 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 524 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 525 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 525 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 526 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 526 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 527 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 527 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 528 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 528 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 529 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 529 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 530 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 530 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 531 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 531 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 532 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 532 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 533 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 533 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 534 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 534 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 535 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 535 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 536 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 536 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 537 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 537 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 538 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 538 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 539 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 539 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 540 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 540 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 541 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 541 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 542 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 542 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 543 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 543 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 544 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 544 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 545 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 545 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 546 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 546 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 547 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 547 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 548 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 548 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 549 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 549 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 550 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 550 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 551 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 551 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 552 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 552 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 553 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 553 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 554 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 554 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 555 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 555 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 556 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 556 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 557 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 557 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 558 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 558 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 559 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 559 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 560 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 560 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 561 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 561 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 562 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 562 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 563 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 563 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 564 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 564 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 565 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 565 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 566 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 566 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 567 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 567 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 568 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 568 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 569 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 569 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 570 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 570 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 571 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 571 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 572 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 572 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 573 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 573 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 574 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 574 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 575 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 575 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 576 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 576 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 577 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 577 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 578 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 578 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 579 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 579 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 580 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 580 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 581 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 581 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 582 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 582 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 583 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 583 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 584 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 584 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 585 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 585 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 586 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 586 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 587 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 587 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 588 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 588 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 589 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 589 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 590 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 590 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 591 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 591 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 592 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 592 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 593 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 593 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 594 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 594 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 595 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 595 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 596 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 596 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 597 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 597 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 598 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 598 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 599 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 599 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 600 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 600 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 601 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 601 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 602 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 602 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 603 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 603 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 604 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 604 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 605 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 605 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 606 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 606 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 607 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 607 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 608 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 608 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 609 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 609 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 610 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 610 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 611 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 611 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 612 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 612 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 613 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 613 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 614 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 614 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 615 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 615 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 616 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 616 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 617 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 617 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 618 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 618 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 619 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 619 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 620 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 620 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 621 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 621 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 622 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 622 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 623 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 623 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 624 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 624 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 625 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 625 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 626 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 626 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 627 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 627 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 628 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 628 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 629 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 629 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 630 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 630 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 631 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 631 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 632 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 632 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 633 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 633 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 634 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 634 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 635 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 635 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 636 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 636 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 637 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 637 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 638 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 638 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 639 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 639 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 640 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 640 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 641 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 641 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 642 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 642 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 643 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 643 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 644 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 644 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 645 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 645 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 646 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 646 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 647 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 647 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 648 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 648 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 649 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 649 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 650 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 650 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 651 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 651 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 652 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 652 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 653 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 653 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 654 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 654 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 655 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 655 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 656 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 656 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 657 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 657 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 658 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 658 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 659 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 659 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 660 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 660 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 661 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 661 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 662 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 662 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 663 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 663 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 664 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 664 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 665 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 665 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 666 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 666 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 667 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 667 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 668 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 668 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 669 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 669 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 670 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 670 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 671 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 671 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 672 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 672 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 673 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 673 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 674 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 674 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 675 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 675 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 676 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 676 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 677 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 677 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 678 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 678 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 679 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 679 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 680 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 680 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 681 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 681 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 682 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 682 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 683 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 683 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 684 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 684 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 685 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 685 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 686 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 686 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 687 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 687 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 688 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 688 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 689 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 689 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 690 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 690 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 691 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 691 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 692 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 692 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 693 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 693 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 694 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 694 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 695 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 695 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 696 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 696 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 697 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 697 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 698 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 698 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 699 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 699 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 700 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 700 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 701 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 701 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 702 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 702 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 703 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 703 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 704 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 704 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 705 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 705 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 706 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 706 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 707 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 707 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 708 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 708 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 709 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 709 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 710 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 710 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 711 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 711 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 712 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 712 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 713 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 713 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 714 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 714 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 715 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 715 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 716 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 716 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 717 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 717 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 718 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 718 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 719 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 719 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 720 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 720 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 721 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 721 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 722 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 722 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 723 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 723 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 724 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 724 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 725 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 725 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 726 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 726 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 727 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 727 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 728 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 728 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 729 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 729 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 730 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 730 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 731 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 731 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 732 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 732 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 733 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 733 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 734 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 734 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 735 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 735 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 736 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 736 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 737 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 737 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 738 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 738 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 739 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 739 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 740 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 740 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 741 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 741 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 742 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 742 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 743 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 743 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 744 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 744 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 745 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 745 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 746 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 746 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 747 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 747 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 748 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 748 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 749 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 749 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 750 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 750 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 751 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 751 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 752 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 752 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 753 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 753 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 754 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 754 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 755 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 755 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 756 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 756 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 757 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 757 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 758 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 758 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 759 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 759 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 760 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 760 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 761 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 761 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 762 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 762 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 763 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 763 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 764 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 764 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 765 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 765 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 766 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 766 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 767 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 767 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 768 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 768 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 769 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 769 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 770 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 770 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 771 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 771 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 772 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 772 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 773 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 773 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 774 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 774 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 775 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 775 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 776 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 776 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 777 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 777 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 778 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 778 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 779 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 779 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 780 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 780 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 781 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 781 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 782 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 782 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 783 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 783 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 784 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 784 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 785 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 785 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 786 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 786 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 787 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 787 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 788 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 788 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 789 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 789 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 790 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 790 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 791 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 791 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 792 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 792 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 793 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 793 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 794 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 794 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 795 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 795 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 796 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 796 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 797 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 797 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 798 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 798 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 799 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 799 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 800 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 800 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 801 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 801 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 802 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 802 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 803 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 803 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 804 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 804 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 805 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 805 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 806 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 806 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 807 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 807 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 808 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 808 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 809 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 809 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 810 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 810 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 811 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 811 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 812 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 812 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 813 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 813 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 814 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 814 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 815 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 815 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 816 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 816 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 817 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 817 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 818 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 818 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 819 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 819 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 820 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 820 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 821 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 821 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 822 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 822 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 823 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 823 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 824 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 824 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 825 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 825 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 826 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 826 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 827 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 827 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 828 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 828 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 829 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 829 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 830 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 830 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 831 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 831 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 832 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 832 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 833 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 833 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 834 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 834 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 835 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 835 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 836 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 836 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 837 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 837 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 838 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 838 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 839 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 839 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 840 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 840 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 841 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 841 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 842 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 842 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 843 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 843 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 844 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 844 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 845 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 845 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 846 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 846 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 847 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 847 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 848 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 848 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 849 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 849 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 850 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 850 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 851 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 851 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 852 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 852 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 853 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 853 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 854 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 854 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 855 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 855 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 856 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 856 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 857 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 857 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 858 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 858 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 859 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 859 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 860 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 860 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 861 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 861 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 862 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 862 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 863 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 863 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 864 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 864 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 865 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 865 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 866 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 866 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 867 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 867 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 868 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 868 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 869 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 869 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 870 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 870 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 871 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 871 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 872 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 872 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 873 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 873 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 874 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 874 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 875 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 875 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 876 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 876 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 877 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 877 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 878 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 878 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 879 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 879 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 880 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 880 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 881 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 881 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 882 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 882 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 883 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 883 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 884 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 884 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 885 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 885 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 886 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 886 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 887 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 887 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 888 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 888 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 889 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 889 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 890 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 890 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 891 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 891 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 892 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 892 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 893 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 893 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 894 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 894 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 895 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 895 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 896 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 896 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 897 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 897 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 898 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 898 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 899 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 899 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 900 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 900 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 901 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 901 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 902 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 902 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 903 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 903 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 904 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 904 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 905 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 905 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 906 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 906 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 907 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 907 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 908 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 908 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 909 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 909 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 910 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 910 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 911 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 911 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 912 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 912 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 913 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 913 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 914 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 914 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 915 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 915 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 916 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 916 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 917 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 917 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 918 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 918 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 919 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 919 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 920 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 920 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 921 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 921 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 922 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 922 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 923 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 923 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 924 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 924 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 925 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 925 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 926 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 926 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 927 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 927 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 928 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 928 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 929 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 929 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 930 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 930 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 931 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 931 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 932 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 932 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 933 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 933 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 934 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 934 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 935 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 935 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 936 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 936 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 937 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 937 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 938 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 938 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 939 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 939 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 940 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 940 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 941 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 941 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 942 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 942 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 943 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 943 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 944 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 944 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 945 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 945 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 946 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 946 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 947 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 947 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 948 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 948 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 949 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 949 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 950 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 950 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 951 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 951 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 952 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 952 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 953 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 953 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 954 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 954 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 955 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 955 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 956 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 956 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 957 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 957 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 958 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 958 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 959 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 959 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 960 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 960 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 961 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 961 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 962 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 962 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 963 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 963 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 964 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 964 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 965 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 965 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 966 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 966 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 967 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 967 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 968 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 968 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 969 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 969 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 970 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 970 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 971 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 971 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 972 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 972 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 973 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 973 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 974 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 974 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 975 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 975 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 976 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 976 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 977 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 977 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 978 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 978 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 979 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 979 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 980 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 980 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 981 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 981 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 982 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 982 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 983 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 983 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 984 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 984 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 985 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 985 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 986 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 986 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 987 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 987 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 988 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 988 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 989 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 989 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 990 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 990 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 991 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 991 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 992 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 992 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 993 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 993 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 994 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 994 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 995 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 995 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 996 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 996 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 997 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 997 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 998 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 998 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 999 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 999 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1000 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1000 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1001 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1001 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1002 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1002 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1003 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1003 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1004 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1004 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1005 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1005 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1006 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1006 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1007 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1007 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1008 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1008 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1009 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1009 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1010 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1010 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1011 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1011 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1012 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1012 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1013 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1013 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1014 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1014 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1015 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1015 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1016 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1016 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1017 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1017 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1018 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1018 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1019 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1019 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1020 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1020 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1021 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1021 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1022 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1022 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1023 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1023 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1024 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1024 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1025 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1025 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1026 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1026 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1027 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1027 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1028 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1028 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1029 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1029 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1030 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1030 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1031 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1031 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1032 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1032 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1033 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1033 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1034 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1034 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1035 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1035 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1036 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1036 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1037 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1037 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1038 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1038 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1039 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1039 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1040 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1040 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1041 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1041 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1042 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1042 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1043 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1043 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1044 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1044 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1045 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1045 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1046 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1046 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1047 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1047 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1048 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1048 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1049 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1049 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1050 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1050 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1051 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1051 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1052 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1052 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1053 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1053 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1054 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1054 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1055 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1055 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1056 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1056 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1057 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1057 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1058 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1058 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1059 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1059 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1060 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1060 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1061 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1061 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1062 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1062 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1063 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1063 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1064 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1064 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1065 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1065 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1066 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1066 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1067 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1067 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1068 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1068 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1069 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1069 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1070 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1070 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1071 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1071 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1072 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1072 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1073 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1073 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1074 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1074 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1075 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1075 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1076 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1076 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1077 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1077 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1078 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1078 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1079 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1079 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1080 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1080 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1081 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1081 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1082 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1082 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1083 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1083 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1084 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1084 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1085 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1085 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1086 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1086 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1087 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1087 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1088 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1088 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1089 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1089 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1090 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1090 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1091 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1091 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1092 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1092 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1093 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1093 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1094 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1094 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1095 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1095 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1096 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1096 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1097 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1097 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1098 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1098 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1099 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1099 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1100 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1100 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1101 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1101 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1102 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1102 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1103 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1103 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1104 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1104 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1105 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1105 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1106 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1106 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1107 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1107 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1108 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1108 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1109 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1109 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1110 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1110 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1111 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1111 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1112 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1112 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1113 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1113 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1114 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1114 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1115 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1115 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1116 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1116 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1117 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1117 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1118 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1118 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1119 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1119 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1120 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1120 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1121 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1121 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1122 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1122 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1123 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1123 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1124 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1124 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1125 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1125 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1126 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1126 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1127 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1127 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1128 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1128 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1129 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1129 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1130 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1130 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1131 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1131 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1132 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1132 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1133 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1133 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1134 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1134 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1135 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1135 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1136 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1136 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1137 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1137 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1138 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1138 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1139 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1139 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1140 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1140 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1141 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1141 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1142 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1142 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1143 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1143 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1144 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1144 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1145 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1145 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1146 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1146 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1147 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1147 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1148 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1148 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1149 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1149 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1150 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1150 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1151 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1151 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1152 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1152 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1153 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1153 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1154 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1154 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1155 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1155 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1156 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1156 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1157 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1157 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1158 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1158 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1159 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1159 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1160 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1160 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1161 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1161 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1162 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1162 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1163 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1163 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1164 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1164 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1165 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1165 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1166 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1166 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1167 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1167 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1168 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1168 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1169 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1169 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1170 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1170 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1171 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1171 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1172 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1172 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1173 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1173 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1174 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1174 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1175 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1175 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1176 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1176 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1177 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1177 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1178 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1178 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1179 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1179 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1180 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1180 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1181 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1181 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1182 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1182 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1183 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1183 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1184 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1184 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1185 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1185 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1186 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1186 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1187 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1187 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1188 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1188 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1189 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1189 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1190 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1190 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1191 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1191 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1192 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1192 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1193 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1193 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1194 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1194 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1195 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1195 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1196 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1196 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1197 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1197 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1198 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1198 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1199 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1199 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1200 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1200 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1201 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1201 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Met Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1202 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1202 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1203 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1203 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1204 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1204 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1205 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1205 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1206 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1206 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1207 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1207 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1208 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1208 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1209 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1209 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1210 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1210 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1211 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1211 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1212 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1212 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1213 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1213 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1214 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1214 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1215 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1215 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1216 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1216 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1217 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1217 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1218 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1218 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1219 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1219 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1220 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1220 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1221 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1221 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1222 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1222 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1223 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1223 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1224 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1224 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1225 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1225 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1226 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1226 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1227 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1227 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1228 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1228 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1229 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1229 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1230 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1230 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1231 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1231 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1232 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1232 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1233 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1233 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1234 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1234 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1235 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1235 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1236 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1236 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1237 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1237 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1238 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1238 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1239 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1239 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1240 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1240 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1241 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1241 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1242 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1242 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1243 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1243 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1244 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1244 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1245 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1245 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1246 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1246 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1247 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1247 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1248 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1248 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1249 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1249 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1250 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1250 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1251 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1251 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1252 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1252 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1253 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1253 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1254 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1254 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1255 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1255 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1256 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1256 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1257 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1257 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1258 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1258 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1259 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1259 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1260 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1260 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1261 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1261 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1262 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1262 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1263 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1263 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1264 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1264 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1265 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1265 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1266 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1266 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1267 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1267 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1268 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1268 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1269 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1269 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1270 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1270 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1271 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1271 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1272 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1272 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1273 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1273 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1274 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1274 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1275 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1275 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1276 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1276 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1277 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1277 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1278 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1278 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1279 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1279 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1280 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1280 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1281 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1281 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1282 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1282 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1283 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1283 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1284 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1284 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1285 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1285 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1286 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1286 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1287 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1287 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1288 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1288 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1289 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1289 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1290 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1290 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1291 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1291 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1292 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1292 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1293 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1293 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1294 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1294 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1295 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1295 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1296 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1296 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1297 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1297 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1298 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1298 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1299 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1299 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1300 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1300 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1301 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1301 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1302 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1302 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1303 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1303 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1304 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1304 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1305 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1305 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1306 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1306 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1307 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1307 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1308 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1308 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1309 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1309 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1310 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1310 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1311 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1311 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1312 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1312 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1313 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1313 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1314 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1314 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1315 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1315 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1316 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1316 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1317 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1317 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1318 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1318 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1319 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1319 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1320 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1320 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1321 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1321 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1322 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1322 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1323 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1323 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1324 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1324 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1325 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1325 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1326 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1326 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1327 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1327 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1328 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1328 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1329 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1329 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1330 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1330 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1331 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1331 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1332 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1332 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1333 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1333 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1334 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1334 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1335 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1335 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1336 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1336 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1337 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1337 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1338 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1338 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1339 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1339 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1340 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1340 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1341 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1341 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1342 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1342 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1343 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1343 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1344 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1344 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1345 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1345 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1346 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1346 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1347 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1347 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1348 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1348 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1349 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1349 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1350 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1350 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1351 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1351 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1352 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1352 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1353 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1353 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1354 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1354 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1355 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1355 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1356 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1356 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1357 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1357 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1358 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1358 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1359 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1359 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1360 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1360 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1361 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1361 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1362 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1362 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1363 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1363 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1364 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1364 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1365 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1365 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1366 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1366 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1367 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1367 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1368 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1368 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1369 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1369 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1370 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1370 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1371 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1371 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1372 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1372 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1373 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1373 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1374 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1374 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1375 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1375 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1376 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1376 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1377 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1377 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1378 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1378 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1379 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1379 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1380 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1380 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1381 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1381 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1382 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1382 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1383 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1383 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1384 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1384 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1385 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1385 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1386 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1386 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1387 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1387 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1388 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1388 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1389 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1389 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1390 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1390 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1391 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1391 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1392 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1392 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1393 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1393 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1394 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1394 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1395 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1395 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1396 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1396 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1397 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1397 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1398 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1398 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1399 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1399 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1400 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1400 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1401 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1401 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1402 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1402 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1403 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1403 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1404 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1404 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1405 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1405 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1406 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1406 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1407 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1407 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1408 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1408 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1409 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1409 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1410 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1410 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1411 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1411 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1412 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1412 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1413 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1413 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1414 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1414 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1415 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1415 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1416 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1416 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1417 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1417 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1418 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1418 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1419 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1419 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1420 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1420 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1421 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1421 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1422 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1422 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1423 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1423 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1424 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1424 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1425 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1425 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1426 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1426 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1427 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1427 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1428 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1428 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1429 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1429 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1430 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1430 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1431 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1431 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1432 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1432 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1433 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1433 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1434 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1434 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1435 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1435 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1436 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1436 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1437 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1437 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1438 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1438 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1439 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1439 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1440 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1440 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1441 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1441 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1442 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1442 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1443 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1443 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1444 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1444 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1445 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1445 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1446 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1446 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1447 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1447 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1448 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1448 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1449 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1449 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1450 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1450 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1451 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1451 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1452 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1452 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1453 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1453 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1454 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1454 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1455 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1455 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1456 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1456 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1457 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1457 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1458 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1458 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1459 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1459 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1460 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1460 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1461 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1461 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1462 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1462 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1463 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1463 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1464 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1464 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1465 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1465 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1466 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1466 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1467 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1467 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1468 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1468 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1469 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1469 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1470 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1470 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1471 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1471 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1472 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1472 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1473 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1473 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1474 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1474 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1475 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1475 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1476 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1476 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1477 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1477 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1478 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1478 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1479 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1479 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1480 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1480 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1481 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1481 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1482 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1482 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1483 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1483 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1484 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1484 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1485 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1485 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1486 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1486 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1487 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1487 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1488 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1488 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1489 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1489 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Leu Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1490 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1490 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1491 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1491 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1492 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1492 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1493 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1493 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1494 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1494 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1495 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1495 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1496 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1496 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1497 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1497 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1498 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1498 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1499 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1499 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1500 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1500 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1501 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1501 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1502 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1502 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1503 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1503 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1504 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1504 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1505 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1505 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1506 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1506 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1507 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1507 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1508 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1508 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1509 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1509 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1510 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1510 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1511 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1511 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1512 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1512 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1513 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1513 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1514 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1514 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1515 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1515 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1516 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1516 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1517 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1517 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1518 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1518 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1519 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1519 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1520 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1520 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1521 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1521 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1522 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1522 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1523 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1523 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1524 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1524 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1525 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1525 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1526 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1526 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1527 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1527 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1528 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1528 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1529 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1529 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1530 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1530 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1531 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1531 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1532 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1532 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1533 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1533 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1534 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1534 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1535 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1535 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1536 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1536 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1537 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1537 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1538 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1538 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1539 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1539 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1540 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1540 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1541 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1541 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1542 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1542 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1543 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1543 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1544 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1544 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1545 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1545 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1546 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1546 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1547 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1547 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1548 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1548 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1549 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1549 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1550 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1550 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1551 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1551 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1552 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1552 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1553 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1553 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1554 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1554 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1555 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1555 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1556 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1556 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1557 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1557 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1558 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1558 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1559 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1559 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1560 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1560 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1561 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1561 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1562 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1562 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1563 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1563 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1564 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1564 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1565 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1565 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1566 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1566 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1567 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1567 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1568 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1568 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1569 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1569 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1570 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1570 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1571 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1571 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1572 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1572 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1573 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1573 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1574 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1574 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1575 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1575 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1576 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1576 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1577 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1577 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1578 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1578 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1579 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1579 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1580 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1580 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1581 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1581 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1582 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1582 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1583 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1583 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1584 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1584 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1585 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1585 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Gly Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1586 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1586 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1587 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1587 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1588 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1588 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1589 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1589 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1590 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1590 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1591 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1591 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1592 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1592 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1593 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1593 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1594 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1594 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1595 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1595 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1596 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1596 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1597 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1597 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1598 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1598 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1599 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1599 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1600 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1600 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1601 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1601 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1602 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1602 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1603 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1603 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1604 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1604 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1605 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1605 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1606 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1606 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1607 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1607 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1608 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1608 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1609 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1609 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1610 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1610 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1611 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1611 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1612 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1612 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1613 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1613 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1614 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1614 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1615 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1615 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1616 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1616 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1617 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1617 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1618 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1618 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1619 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1619 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1620 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1620 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1621 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1621 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1622 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1622 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1623 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1623 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1624 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1624 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1625 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1625 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1626 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1626 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1627 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1627 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1628 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1628 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1629 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1629 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1630 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1630 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1631 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1631 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1632 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1632 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1633 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1633 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1634 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1634 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1635 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1635 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1636 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1636 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1637 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1637 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1638 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1638 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1639 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1639 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1640 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1640 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1641 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1641 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1642 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1642 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1643 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1643 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1644 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1644 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1645 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1645 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1646 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1646 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1647 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1647 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1648 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1648 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1649 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1649 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1650 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1650 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1651 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1651 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1652 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1652 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1653 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1653 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1654 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1654 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1655 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1655 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1656 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1656 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1657 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1657 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1658 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1658 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1659 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1659 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1660 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1660 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1661 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1661 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1662 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1662 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1663 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1663 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1664 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1664 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1665 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1665 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1666 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1666 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1667 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1667 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1668 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1668 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1669 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1669 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1670 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1670 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1671 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1671 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1672 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1672 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1673 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1673 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1674 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1674 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1675 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1675 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1676 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1676 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1677 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1677 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1678 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1678 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1679 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1679 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1680 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1680 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1681 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1681 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Thr Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1682 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1682 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1683 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1683 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1684 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1684 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1685 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1685 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1686 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1686 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1687 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1687 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1688 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1688 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1689 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1689 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1690 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1690 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1691 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1691 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1692 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1692 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1693 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1693 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1694 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1694 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1695 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1695 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1696 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1696 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1697 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1697 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1698 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1698 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1699 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1699 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1700 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1700 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1701 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1701 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1702 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1702 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1703 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1703 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1704 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1704 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1705 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1705 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1706 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1706 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1707 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1707 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1708 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1708 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1709 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1709 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1710 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1710 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1711 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1711 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1712 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1712 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1713 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1713 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1714 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1714 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1715 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1715 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1716 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1716 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1717 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1717 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1718 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1718 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1719 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1719 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1720 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1720 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1721 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1721 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1722 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1722 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1723 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1723 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1724 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1724 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1725 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1725 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1726 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1726 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1727 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1727 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1728 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1728 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1729 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1729 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Thr Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1730 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1730 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1731 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1731 Leu Ser Thr Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1732 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1732 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1733 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1733 Leu Ser Trp Ala Ala Asp Met Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1734 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1734 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1735 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1735 Leu Ser Thr Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1736 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1736 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1737 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1737 Leu Ser Trp Ala Ala Asp Leu Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1738 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1738 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1739 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1739 Leu Ser Thr Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1740 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1740 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1741 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1741 Leu Ser Trp Ala Ala Asp Val Gln Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1742 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1742 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1743 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1743 Leu Ser Thr Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1744 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1744 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1745 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1745 Leu Ser Trp Ala Ala Asp Met Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1746 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1746 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1747 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1747 Leu Ser Thr Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1748 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1748 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1749 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1749 Leu Ser Trp Ala Ala Asp Leu Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1750 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1750 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1751 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1751 Leu Ser Thr Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1752 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1752 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1753 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1753 Leu Ser Trp Ala Ala Asp Val Trp Gly Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1754 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1754 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1755 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1755 Leu Ser Thr Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1756 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1756 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1757 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1757 Leu Ser Trp Ala Ala Asp Met Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1758 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1758 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1759 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1759 Leu Ser Thr Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1760 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1760 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1761 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1761 Leu Ser Trp Ala Ala Asp Leu Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1762 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1762 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1763 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1763 Leu Ser Thr Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1764 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1764 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1765 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1765 Leu Ser Trp Ala Ala Asp Val Gln Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1766 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1766 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1767 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1767 Leu Ser Thr Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1768 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1768 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1769 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1769 Leu Ser Trp Ala Ala Asp Met Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1770 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1770 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1771 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1771 Leu Ser Thr Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1772 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1772 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1773 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1773 Leu Ser Trp Ala Ala Asp Leu Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1774 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1774 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1775 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1775 Leu Ser Thr Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1776 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 1776 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1777 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1777 Leu Ser Trp Ala Ala Asp Val Trp Ala Val Val Trp Asp Trp Val Ala 1 5 10 15 Ser Gly Leu Asp Lys Asp Tyr Leu Lys Pro Asp Asp 20 25 <210> 1778 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1778 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1779 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1779 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1780 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1780 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1781 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1781 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1782 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1782 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1783 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1783 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1784 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1784 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1785 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1785 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1786 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1786 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1787 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1787 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1788 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1788 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1789 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1789 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1790 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1790 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1791 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1791 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1792 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1792 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1793 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1793 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1794 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1794 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1795 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1795 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1796 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1796 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1797 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1797 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1798 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1798 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1799 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1799 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1800 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1800 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1801 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1801 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1802 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1802 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1803 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1803 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1804 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1804 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1805 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1805 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1806 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1806 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1807 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1807 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1808 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1808 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1809 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1809 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1810 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1810 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1811 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1811 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1812 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1812 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1813 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1813 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1814 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1814 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1815 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1815 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1816 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1816 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1817 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1817 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1818 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1818 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1819 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1819 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1820 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1820 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1821 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1821 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1822 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1822 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1823 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1823 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1824 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1824 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1825 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1825 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1826 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1826 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1827 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1827 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1828 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1828 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1829 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1829 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1830 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1830 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1831 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1831 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1832 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1832 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1833 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1833 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1834 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1834 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1835 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1835 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1836 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1836 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1837 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1837 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1838 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1838 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1839 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1839 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1840 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1840 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1841 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1841 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1842 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1842 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1843 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1843 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1844 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1844 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1845 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1845 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1846 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1846 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1847 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1847 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1848 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1848 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1849 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1849 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1850 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1850 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1851 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1851 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1852 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1852 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1853 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1853 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1854 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1854 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1855 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1855 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1856 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1856 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1857 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1857 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1858 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1858 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1859 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1859 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1860 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1860 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1861 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1861 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1862 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1862 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1863 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1863 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1864 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1864 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1865 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1865 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1866 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1866 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1867 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1867 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1868 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1868 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1869 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1869 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1870 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1870 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1871 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1871 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1872 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1872 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1873 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1873 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1874 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1874 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1875 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1875 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1876 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1876 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1877 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1877 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1878 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1878 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1879 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1879 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1880 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1880 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1881 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1881 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1882 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1882 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1883 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1883 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1884 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1884 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1885 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1885 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1886 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1886 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1887 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1887 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1888 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1888 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1889 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1889 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1890 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1890 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1891 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1891 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1892 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1892 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1893 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1893 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1894 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1894 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1895 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1895 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1896 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1896 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1897 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1897 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1898 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1898 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1899 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1899 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1900 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1900 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1901 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1901 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1902 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1902 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1903 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1903 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1904 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1904 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1905 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1905 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1906 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1906 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1907 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1907 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1908 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1908 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1909 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1909 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1910 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1910 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1911 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1911 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1912 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1912 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1913 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1913 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1914 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1914 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1915 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1915 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1916 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1916 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1917 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1917 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1918 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1918 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1919 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1919 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1920 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1920 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1921 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1921 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1922 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1922 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1923 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1923 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1924 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1924 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1925 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1925 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1926 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1926 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1927 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1927 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1928 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1928 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1929 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1929 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1930 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1930 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1931 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1931 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1932 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1932 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1933 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1933 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1934 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1934 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1935 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1935 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1936 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1936 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1937 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1937 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1938 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1938 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1939 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1939 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1940 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1940 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1941 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1941 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1942 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1942 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1943 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1943 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1944 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1944 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1945 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1945 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1946 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1946 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1947 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1947 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1948 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1948 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1949 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1949 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1950 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1950 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1951 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1951 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1952 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1952 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1953 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1953 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1954 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1954 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1955 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1955 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1956 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1956 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1957 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1957 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1958 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1958 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1959 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1959 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1960 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1960 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1961 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1961 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1962 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1962 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1963 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1963 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1964 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1964 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1965 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1965 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1966 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1966 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1967 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1967 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1968 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1968 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1969 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1969 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1970 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1970 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1971 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1971 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1972 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1972 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1973 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1973 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1974 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1974 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1975 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1975 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1976 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1976 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1977 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1977 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1978 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1978 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1979 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1979 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1980 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1980 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1981 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1981 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1982 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1982 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1983 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1983 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1984 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1984 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1985 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1985 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1986 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1986 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1987 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1987 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1988 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1988 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1989 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1989 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 1990 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1990 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1991 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1991 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 1992 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1992 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1993 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1993 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 1994 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1994 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1995 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1995 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 1996 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1996 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1997 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1997 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 1998 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 1998 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 1999 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 1999 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2000 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2000 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2001 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2001 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2002 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2002 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2003 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2003 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2004 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2004 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2005 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2005 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2006 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2006 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2007 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2007 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2008 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2008 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2009 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2009 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2010 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2010 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2011 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2011 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2012 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2012 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2013 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2013 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2014 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2014 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2015 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2015 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2016 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2016 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2017 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2017 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2018 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2018 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2019 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2019 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2020 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2020 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2021 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2021 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2022 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2022 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2023 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2023 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2024 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2024 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2025 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2025 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2026 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2026 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2027 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2027 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2028 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2028 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2029 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2029 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2030 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2030 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2031 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2031 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2032 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2032 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2033 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2033 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2034 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2034 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2035 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2035 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2036 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2036 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2037 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2037 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2038 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2038 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2039 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2039 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2040 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2040 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2041 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2041 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2042 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2042 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2043 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2043 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2044 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2044 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2045 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2045 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2046 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2046 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2047 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2047 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2048 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2048 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2049 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2049 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2050 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2050 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2051 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2051 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2052 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2052 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2053 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2053 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2054 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2054 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2055 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2055 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2056 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2056 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2057 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2057 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2058 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2058 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2059 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2059 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2060 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2060 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2061 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2061 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2062 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2062 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2063 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2063 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2064 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2064 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2065 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2065 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2066 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2066 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2067 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2067 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2068 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2068 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2069 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2069 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2070 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2070 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2071 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2071 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2072 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2072 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2073 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2073 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2074 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2074 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2075 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2075 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2076 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2076 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2077 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2077 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2078 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2078 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2079 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2079 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2080 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2080 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2081 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2081 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2082 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2082 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2083 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2083 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2084 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2084 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2085 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2085 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2086 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2086 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2087 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2087 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2088 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2088 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2089 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2089 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2090 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2090 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2091 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2091 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2092 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2092 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2093 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2093 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2094 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2094 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2095 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2095 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2096 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2096 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2097 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2097 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2098 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2098 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2099 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2099 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2100 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2100 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2101 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2101 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2102 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2102 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2103 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2103 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2104 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2104 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2105 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2105 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2106 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2106 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2107 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2107 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2108 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2108 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2109 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2109 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2110 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2110 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2111 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2111 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2112 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2112 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2113 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2113 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2114 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2114 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2115 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2115 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2116 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2116 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2117 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2117 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2118 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2118 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2119 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2119 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2120 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2120 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2121 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2121 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2122 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2122 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2123 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2123 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2124 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2124 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2125 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2125 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2126 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2126 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2127 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2127 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2128 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2128 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2129 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2129 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2130 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2130 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2131 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2131 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2132 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2132 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2133 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2133 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2134 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2134 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2135 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2135 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2136 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2136 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2137 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2137 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2138 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2138 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2139 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2139 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2140 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2140 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2141 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2141 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2142 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2142 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2143 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2143 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2144 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2144 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2145 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2145 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2146 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2146 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2147 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2147 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2148 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2148 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2149 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2149 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2150 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2150 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2151 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2151 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2152 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2152 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2153 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2153 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2154 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2154 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2155 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2155 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2156 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2156 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2157 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2157 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2158 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2158 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2159 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2159 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2160 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2160 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2161 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2161 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2162 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2162 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2163 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2163 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2164 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2164 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2165 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2165 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2166 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2166 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2167 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2167 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2168 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2168 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2169 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2169 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2170 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2170 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2171 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2171 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2172 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2172 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2173 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2173 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2174 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2174 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2175 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2175 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2176 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2176 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2177 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2177 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2178 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2178 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2179 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2179 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2180 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2180 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2181 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2181 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2182 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2182 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2183 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2183 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2184 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2184 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2185 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2185 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2186 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2186 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2187 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2187 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2188 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2188 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2189 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2189 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2190 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2190 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2191 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2191 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2192 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2192 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2193 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2193 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2194 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2194 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2195 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2195 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2196 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2196 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2197 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2197 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2198 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2198 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2199 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2199 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2200 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2200 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2201 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2201 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2202 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2202 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2203 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2203 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2204 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2204 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2205 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2205 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2206 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2206 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2207 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2207 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2208 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2208 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2209 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2209 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2210 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2210 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2211 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2211 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2212 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2212 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2213 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2213 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2214 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2214 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2215 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2215 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2216 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2216 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2217 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2217 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2218 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2218 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2219 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2219 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2220 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2220 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2221 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2221 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2222 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2222 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2223 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2223 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2224 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2224 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2225 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2225 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2226 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2226 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2227 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2227 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2228 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2228 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2229 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2229 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2230 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2230 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2231 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2231 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2232 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2232 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2233 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2233 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2234 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2234 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2235 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2235 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2236 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2236 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2237 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2237 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2238 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2238 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2239 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2239 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2240 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2240 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2241 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2241 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2242 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2242 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2243 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2243 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2244 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2244 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2245 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2245 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2246 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2246 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2247 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2247 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2248 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2248 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2249 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2249 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2250 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2250 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2251 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2251 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2252 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2252 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2253 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2253 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2254 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2254 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2255 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2255 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2256 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2256 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2257 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2257 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2258 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2258 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2259 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2259 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2260 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2260 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2261 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2261 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2262 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2262 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2263 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2263 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2264 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2264 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2265 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2265 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2266 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2266 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2267 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2267 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2268 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2268 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2269 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2269 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2270 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2270 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2271 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2271 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2272 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2272 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2273 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2273 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2274 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2274 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2275 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2275 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2276 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2276 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2277 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2277 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2278 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2278 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2279 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2279 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2280 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2280 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2281 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2281 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2282 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2282 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2283 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2283 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2284 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2284 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2285 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2285 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2286 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2286 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2287 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2287 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2288 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2288 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2289 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2289 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2290 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2290 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2291 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2291 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2292 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2292 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2293 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2293 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2294 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2294 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2295 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2295 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2296 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2296 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2297 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2297 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2298 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2298 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2299 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2299 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2300 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2300 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2301 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2301 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2302 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2302 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2303 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2303 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2304 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2304 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2305 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2305 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2306 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2306 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2307 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2307 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2308 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2308 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2309 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2309 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2310 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2310 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2311 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2311 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2312 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2312 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2313 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2313 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2314 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2314 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2315 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2315 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2316 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2316 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2317 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2317 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2318 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2318 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2319 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2319 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2320 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2320 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2321 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2321 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2322 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2322 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2323 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2323 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2324 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2324 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2325 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2325 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2326 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2326 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2327 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2327 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2328 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2328 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2329 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2329 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2330 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2330 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2331 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2331 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2332 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2332 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2333 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2333 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2334 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2334 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2335 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2335 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2336 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2336 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2337 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2337 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2338 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2338 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2339 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2339 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2340 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2340 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2341 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2341 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2342 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2342 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2343 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2343 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2344 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2344 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2345 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2345 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2346 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2346 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2347 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2347 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2348 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2348 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2349 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2349 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2350 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2350 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2351 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2351 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2352 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2352 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2353 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2353 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2354 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2354 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2355 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2355 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2356 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2356 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2357 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2357 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2358 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2358 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2359 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2359 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2360 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2360 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2361 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2361 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2362 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2362 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2363 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2363 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2364 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2364 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2365 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2365 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2366 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2366 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2367 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2367 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2368 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2368 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2369 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2369 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2370 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2370 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2371 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2371 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2372 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2372 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2373 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2373 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2374 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2374 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2375 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2375 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2376 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2376 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2377 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2377 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2378 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2378 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2379 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2379 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2380 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2380 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2381 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2381 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2382 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2382 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2383 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2383 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2384 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2384 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2385 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2385 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2386 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2386 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2387 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2387 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2388 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2388 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2389 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2389 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2390 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2390 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2391 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2391 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2392 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2392 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2393 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2393 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2394 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2394 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2395 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2395 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2396 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2396 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2397 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2397 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2398 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2398 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2399 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2399 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2400 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2400 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2401 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2401 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2402 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2402 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2403 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2403 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2404 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2404 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2405 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2405 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2406 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2406 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2407 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2407 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2408 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2408 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2409 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2409 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2410 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2410 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2411 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2411 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2412 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2412 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2413 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2413 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2414 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2414 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2415 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2415 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2416 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2416 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2417 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2417 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2418 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2418 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2419 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2419 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2420 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2420 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2421 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2421 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2422 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2422 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2423 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2423 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2424 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2424 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2425 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2425 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2426 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2426 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2427 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2427 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2428 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2428 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2429 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2429 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2430 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2430 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2431 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2431 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2432 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2432 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2433 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2433 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2434 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2434 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2435 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2435 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2436 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2436 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2437 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2437 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2438 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2438 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2439 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2439 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2440 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2440 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2441 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2441 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2442 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2442 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2443 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2443 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2444 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2444 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2445 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2445 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2446 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2446 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2447 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2447 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2448 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2448 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2449 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2449 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2450 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2450 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2451 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2451 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2452 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2452 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2453 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2453 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2454 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2454 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2455 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2455 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2456 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2456 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2457 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2457 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2458 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2458 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2459 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2459 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2460 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2460 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2461 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2461 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2462 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2462 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2463 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2463 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2464 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2464 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2465 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2465 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2466 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2466 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2467 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2467 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2468 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2468 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2469 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2469 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2470 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2470 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2471 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2471 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2472 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2472 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2473 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2473 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2474 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2474 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2475 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2475 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2476 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2476 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2477 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2477 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2478 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2478 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2479 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2479 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2480 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2480 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2481 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2481 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2482 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2482 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2483 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2483 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2484 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2484 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2485 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2485 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2486 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2486 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2487 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2487 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2488 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2488 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2489 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2489 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2490 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2490 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2491 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2491 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2492 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2492 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2493 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2493 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2494 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2494 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2495 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2495 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2496 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2496 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2497 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2497 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2498 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2498 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2499 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2499 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2500 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2500 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2501 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2501 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2502 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2502 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2503 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2503 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2504 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2504 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2505 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2505 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2506 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2506 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2507 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2507 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2508 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2508 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2509 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2509 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2510 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2510 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2511 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2511 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2512 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2512 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2513 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2513 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2514 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2514 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2515 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2515 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2516 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2516 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2517 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2517 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2518 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2518 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2519 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2519 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2520 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2520 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2521 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2521 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2522 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2522 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2523 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2523 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2524 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2524 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2525 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2525 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2526 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2526 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2527 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2527 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2528 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2528 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2529 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2529 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2530 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2530 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2531 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2531 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2532 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2532 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2533 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2533 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2534 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2534 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2535 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2535 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2536 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2536 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2537 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2537 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2538 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2538 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2539 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2539 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2540 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2540 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2541 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2541 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2542 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2542 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2543 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2543 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2544 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2544 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2545 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2545 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2546 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2546 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2547 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2547 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2548 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2548 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2549 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2549 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2550 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2550 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2551 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2551 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2552 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2552 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2553 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2553 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2554 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2554 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2555 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2555 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2556 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2556 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2557 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2557 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2558 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2558 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2559 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2559 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2560 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2560 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2561 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2561 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2562 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2562 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2563 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2563 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2564 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2564 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2565 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2565 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2566 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2566 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2567 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2567 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2568 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2568 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2569 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2569 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2570 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2570 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2571 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2571 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2572 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2572 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2573 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2573 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2574 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2574 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2575 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2575 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2576 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2576 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2577 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2577 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2578 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2578 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2579 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2579 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2580 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2580 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2581 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2581 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2582 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2582 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2583 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2583 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2584 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2584 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2585 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2585 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2586 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2586 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2587 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2587 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2588 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2588 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2589 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2589 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2590 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2590 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2591 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2591 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2592 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2592 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2593 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2593 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2594 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2594 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2595 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2595 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2596 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2596 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2597 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2597 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2598 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2598 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2599 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2599 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2600 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2600 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2601 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2601 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2602 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2602 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2603 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2603 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2604 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2604 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2605 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2605 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2606 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2606 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2607 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2607 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2608 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2608 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2609 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2609 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2610 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2610 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2611 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2611 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2612 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2612 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2613 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2613 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2614 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2614 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2615 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2615 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2616 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2616 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2617 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2617 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2618 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2618 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2619 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2619 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2620 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2620 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2621 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2621 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2622 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2622 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2623 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2623 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2624 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2624 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2625 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2625 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2626 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2626 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2627 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2627 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2628 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2628 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2629 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2629 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2630 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2630 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2631 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2631 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2632 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2632 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2633 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2633 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2634 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2634 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2635 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2635 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2636 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2636 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2637 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2637 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2638 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2638 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2639 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2639 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2640 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <220> <223> C-terminus amidated <400> 2640 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2641 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> N-terminus acetylated <400> 2641 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2642 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2642 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2643 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2643 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2644 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2644 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2645 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2645 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2646 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2646 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2647 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2647 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2648 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2648 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2649 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2649 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2650 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2650 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2651 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2651 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2652 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2652 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2653 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2653 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2654 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2654 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2655 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2655 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2656 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2656 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2657 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2657 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2658 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2658 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2659 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2659 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2660 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2660 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2661 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2661 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2662 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2662 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2663 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2663 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2664 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2664 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2665 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2665 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2666 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2666 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2667 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2667 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2668 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2668 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2669 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2669 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2670 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2670 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2671 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2671 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2672 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2672 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2673 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2673 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2674 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2674 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2675 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2675 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2676 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2676 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2677 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2677 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2678 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2678 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2679 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2679 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2680 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2680 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2681 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2681 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2682 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2682 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2683 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2683 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2684 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2684 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2685 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2685 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2686 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2686 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2687 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2687 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2688 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2688 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2689 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2689 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2690 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2690 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2691 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2691 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2692 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2692 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2693 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2693 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2694 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2694 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2695 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2695 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2696 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2696 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2697 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2697 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2698 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2698 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2699 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2699 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2700 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2700 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2701 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2701 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2702 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2702 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2703 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2703 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2704 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2704 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2705 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2705 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2706 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2706 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2707 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2707 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2708 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2708 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2709 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2709 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2710 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2710 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2711 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2711 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2712 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2712 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2713 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2713 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2714 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2714 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2715 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2715 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2716 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2716 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2717 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2717 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2718 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2718 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2719 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2719 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2720 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2720 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2721 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2721 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2722 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2722 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2723 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2723 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2724 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2724 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2725 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2725 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2726 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2726 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2727 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2727 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2728 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2728 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2729 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2729 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2730 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2730 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2731 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2731 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2732 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2732 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2733 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2733 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2734 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2734 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2735 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2735 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2736 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2736 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2737 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2737 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2738 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2738 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2739 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2739 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2740 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2740 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2741 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2741 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2742 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2742 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2743 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2743 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2744 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2744 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2745 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2745 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2746 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2746 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2747 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2747 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2748 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2748 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2749 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2749 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2750 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2750 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2751 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2751 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2752 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2752 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2753 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2753 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2754 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2754 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2755 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2755 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2756 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2756 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2757 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2757 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2758 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2758 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2759 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2759 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2760 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2760 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2761 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2761 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2762 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2762 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2763 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2763 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2764 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2764 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2765 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2765 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2766 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2766 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2767 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2767 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2768 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2768 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2769 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2769 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2770 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2770 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2771 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2771 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2772 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2772 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2773 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2773 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2774 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2774 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2775 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2775 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2776 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2776 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2777 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2777 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2778 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2778 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2779 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2779 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2780 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2780 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2781 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2781 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2782 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2782 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2783 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2783 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2784 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2784 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2785 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2785 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2786 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2786 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2787 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2787 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2788 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2788 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2789 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2789 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2790 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2790 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2791 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2791 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2792 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2792 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2793 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2793 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2794 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2794 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2795 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2795 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2796 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2796 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2797 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2797 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2798 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2798 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2799 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2799 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2800 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2800 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2801 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2801 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2802 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2802 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2803 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2803 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2804 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2804 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2805 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2805 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2806 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2806 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2807 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2807 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2808 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2808 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2809 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2809 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2810 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2810 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2811 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2811 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2812 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2812 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2813 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2813 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2814 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2814 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2815 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2815 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2816 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2816 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2817 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2817 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2818 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2818 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2819 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2819 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2820 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2820 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2821 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2821 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2822 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2822 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2823 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2823 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2824 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2824 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2825 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2825 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2826 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2826 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2827 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2827 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2828 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2828 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2829 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2829 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2830 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2830 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2831 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2831 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2832 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2832 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2833 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2833 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2834 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2834 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2835 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2835 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2836 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2836 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2837 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2837 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2838 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2838 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2839 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2839 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2840 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2840 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2841 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2841 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2842 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2842 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2843 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2843 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2844 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2844 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2845 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2845 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2846 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2846 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2847 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2847 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2848 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2848 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2849 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2849 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2850 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2850 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2851 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2851 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2852 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2852 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2853 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2853 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2854 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2854 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2855 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2855 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2856 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2856 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2857 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2857 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2858 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2858 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2859 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2859 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2860 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2860 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2861 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2861 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2862 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2862 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2863 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2863 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2864 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2864 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2865 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2865 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2866 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2866 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2867 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2867 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2868 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2868 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2869 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2869 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2870 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2870 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2871 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2871 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2872 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2872 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2873 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2873 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2874 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2874 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2875 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2875 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2876 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2876 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2877 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2877 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2878 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2878 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2879 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2879 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2880 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2880 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2881 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2881 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2882 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2882 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2883 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2883 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2884 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2884 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2885 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2885 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2886 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2886 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2887 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2887 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2888 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2888 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2889 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2889 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2890 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2890 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2891 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2891 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2892 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2892 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2893 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2893 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2894 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2894 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2895 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2895 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2896 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2896 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2897 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2897 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2898 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2898 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2899 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2899 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2900 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2900 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2901 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2901 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2902 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2902 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2903 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2903 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2904 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2904 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2905 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2905 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2906 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2906 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2907 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2907 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2908 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2908 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2909 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2909 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2910 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2910 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2911 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2911 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2912 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2912 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2913 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2913 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2914 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2914 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2915 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2915 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2916 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2916 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2917 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2917 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2918 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2918 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2919 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2919 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2920 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2920 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2921 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2921 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2922 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2922 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2923 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2923 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2924 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2924 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2925 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2925 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2926 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2926 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2927 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2927 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2928 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2928 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2929 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2929 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Val Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2930 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2930 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2931 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2931 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2932 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2932 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2933 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2933 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2934 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2934 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2935 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2935 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2936 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2936 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2937 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2937 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2938 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2938 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2939 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2939 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2940 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2940 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2941 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2941 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2942 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2942 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2943 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2943 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2944 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2944 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2945 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2945 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2946 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2946 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2947 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2947 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2948 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2948 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2949 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2949 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2950 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2950 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2951 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2951 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2952 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2952 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2953 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2953 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2954 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2954 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2955 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2955 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2956 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2956 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2957 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2957 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2958 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2958 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2959 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2959 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2960 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2960 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2961 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2961 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2962 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2962 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2963 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2963 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2964 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2964 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2965 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2965 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2966 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2966 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2967 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2967 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2968 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2968 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2969 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2969 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2970 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2970 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2971 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2971 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2972 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2972 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2973 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2973 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2974 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2974 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2975 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2975 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2976 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2976 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2977 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2977 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2978 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2978 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2979 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2979 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2980 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2980 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2981 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2981 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2982 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2982 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2983 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2983 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2984 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2984 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2985 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2985 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2986 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2986 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2987 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2987 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2988 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2988 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2989 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2989 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 2990 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2990 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2991 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2991 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 2992 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2992 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2993 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2993 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 2994 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2994 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2995 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2995 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 2996 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2996 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2997 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2997 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 2998 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 2998 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 2999 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 2999 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3000 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3000 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3001 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3001 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3002 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3002 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3003 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3003 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3004 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3004 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3005 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3005 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3006 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3006 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3007 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3007 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3008 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3008 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3009 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3009 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3010 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3010 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3011 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3011 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3012 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3012 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3013 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3013 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3014 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3014 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3015 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3015 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3016 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3016 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3017 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3017 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3018 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3018 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3019 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3019 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3020 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3020 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3021 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3021 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3022 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3022 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3023 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3023 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3024 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3024 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3025 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3025 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3026 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3026 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3027 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3027 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3028 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3028 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3029 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3029 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3030 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3030 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3031 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3031 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3032 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3032 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3033 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3033 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3034 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3034 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3035 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3035 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3036 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3036 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3037 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3037 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3038 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3038 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3039 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3039 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3040 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3040 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3041 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3041 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3042 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3042 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3043 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3043 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3044 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3044 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3045 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3045 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3046 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3046 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3047 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3047 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3048 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3048 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3049 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3049 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3050 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3050 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3051 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3051 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3052 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3052 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3053 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3053 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3054 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3054 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3055 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3055 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3056 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3056 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3057 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3057 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3058 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3058 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3059 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3059 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3060 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3060 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3061 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3061 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3062 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3062 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3063 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3063 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3064 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3064 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3065 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3065 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3066 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3066 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3067 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3067 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3068 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3068 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3069 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3069 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3070 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3070 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3071 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3071 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3072 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3072 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3073 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3073 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3074 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3074 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3075 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3075 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3076 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3076 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3077 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3077 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3078 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3078 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3079 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3079 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3080 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3080 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3081 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3081 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3082 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3082 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3083 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3083 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3084 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3084 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3085 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3085 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3086 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3086 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3087 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3087 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3088 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3088 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3089 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3089 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3090 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3090 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3091 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3091 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3092 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3092 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3093 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3093 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3094 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3094 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3095 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3095 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3096 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3096 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3097 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3097 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3098 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3098 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3099 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3099 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3100 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3100 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3101 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3101 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3102 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3102 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3103 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3103 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3104 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3104 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3105 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3105 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3106 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3106 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3107 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3107 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3108 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3108 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3109 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3109 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3110 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3110 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3111 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3111 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3112 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3112 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3113 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3113 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3114 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3114 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3115 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3115 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3116 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3116 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3117 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3117 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3118 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3118 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3119 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3119 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3120 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3120 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3121 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3121 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3122 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3122 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3123 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3123 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3124 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3124 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3125 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3125 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3126 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3126 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3127 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3127 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3128 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3128 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3129 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3129 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3130 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3130 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3131 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3131 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3132 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3132 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3133 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3133 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3134 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3134 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3135 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3135 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3136 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3136 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3137 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3137 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3138 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3138 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3139 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3139 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3140 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3140 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3141 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3141 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3142 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3142 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3143 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3143 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3144 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3144 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3145 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3145 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3146 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3146 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3147 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3147 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3148 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3148 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3149 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3149 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3150 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3150 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3151 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3151 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3152 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3152 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3153 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3153 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3154 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3154 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3155 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3155 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3156 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3156 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3157 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3157 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3158 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3158 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3159 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3159 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3160 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3160 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3161 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3161 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3162 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3162 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3163 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3163 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3164 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3164 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3165 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3165 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3166 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3166 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3167 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3167 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3168 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3168 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3169 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3169 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3170 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3170 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3171 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3171 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3172 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3172 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3173 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3173 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3174 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3174 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3175 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3175 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3176 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3176 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3177 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3177 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3178 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3178 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3179 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3179 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3180 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3180 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3181 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3181 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3182 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3182 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3183 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3183 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3184 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3184 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3185 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3185 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3186 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3186 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3187 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3187 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3188 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3188 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3189 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3189 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3190 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3190 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3191 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3191 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3192 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3192 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3193 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3193 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3194 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3194 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3195 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3195 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3196 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3196 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3197 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3197 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3198 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3198 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3199 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3199 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3200 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3200 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3201 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3201 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3202 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3202 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3203 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3203 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3204 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3204 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3205 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3205 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3206 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3206 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3207 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3207 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3208 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3208 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3209 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3209 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3210 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3210 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3211 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3211 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3212 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3212 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3213 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3213 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3214 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3214 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3215 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3215 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3216 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3216 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3217 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3217 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Leu Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3218 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3218 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3219 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3219 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3220 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3220 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3221 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3221 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3222 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3222 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3223 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3223 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3224 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3224 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3225 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3225 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3226 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3226 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3227 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3227 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3228 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3228 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3229 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3229 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3230 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3230 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3231 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3231 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3232 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3232 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3233 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3233 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3234 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3234 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3235 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3235 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3236 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3236 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3237 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3237 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3238 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3238 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3239 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3239 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3240 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3240 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3241 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3241 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3242 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3242 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3243 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3243 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3244 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3244 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3245 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3245 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3246 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3246 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3247 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3247 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3248 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3248 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3249 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3249 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3250 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3250 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3251 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3251 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3252 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3252 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3253 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3253 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3254 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3254 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3255 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3255 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3256 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3256 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3257 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3257 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3258 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3258 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3259 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3259 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3260 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3260 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3261 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3261 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3262 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3262 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3263 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3263 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3264 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3264 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3265 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3265 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3266 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3266 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3267 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3267 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3268 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3268 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3269 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3269 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3270 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3270 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3271 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3271 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3272 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3272 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3273 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3273 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3274 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3274 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3275 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3275 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3276 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3276 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3277 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3277 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3278 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3278 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3279 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3279 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3280 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3280 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3281 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3281 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3282 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3282 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3283 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3283 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3284 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3284 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3285 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3285 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3286 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3286 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3287 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3287 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3288 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3288 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3289 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3289 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3290 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3290 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3291 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3291 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3292 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3292 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3293 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3293 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3294 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3294 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3295 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3295 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3296 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3296 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3297 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3297 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3298 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3298 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3299 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3299 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3300 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3300 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3301 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3301 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3302 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3302 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3303 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3303 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3304 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3304 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3305 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3305 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3306 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3306 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3307 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3307 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3308 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3308 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3309 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3309 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3310 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3310 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3311 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3311 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3312 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3312 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3313 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3313 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Trp Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3314 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3314 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3315 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3315 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3316 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3316 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3317 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3317 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3318 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3318 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3319 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3319 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3320 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3320 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3321 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3321 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3322 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3322 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3323 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3323 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3324 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3324 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3325 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3325 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3326 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3326 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3327 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3327 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3328 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3328 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3329 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3329 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3330 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3330 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3331 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3331 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3332 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3332 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3333 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3333 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3334 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3334 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3335 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3335 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3336 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3336 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3337 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3337 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3338 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3338 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3339 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3339 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3340 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3340 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3341 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3341 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3342 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3342 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3343 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3343 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3344 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3344 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3345 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3345 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3346 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3346 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3347 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3347 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3348 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3348 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3349 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3349 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3350 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3350 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3351 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3351 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3352 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3352 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3353 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3353 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3354 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3354 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3355 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3355 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3356 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3356 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3357 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3357 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3358 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3358 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3359 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3359 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3360 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3360 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3361 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3361 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3362 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3362 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3363 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3363 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3364 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3364 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3365 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3365 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3366 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3366 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3367 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3367 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3368 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3368 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3369 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3369 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3370 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3370 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3371 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3371 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3372 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3372 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3373 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3373 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3374 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3374 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3375 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3375 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3376 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3376 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3377 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3377 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3378 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3378 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3379 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3379 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3380 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3380 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3381 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3381 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3382 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3382 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3383 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3383 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3384 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3384 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3385 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3385 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3386 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3386 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3387 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3387 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3388 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3388 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3389 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3389 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3390 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3390 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3391 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3391 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3392 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3392 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3393 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3393 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3394 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3394 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3395 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3395 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3396 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3396 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3397 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3397 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3398 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3398 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3399 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3399 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3400 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3400 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3401 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3401 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3402 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3402 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3403 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3403 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3404 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3404 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3405 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3405 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3406 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3406 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3407 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3407 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3408 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3408 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3409 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3409 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Thr Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3410 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3410 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3411 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3411 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3412 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3412 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3413 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3413 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3414 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3414 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3415 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3415 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3416 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3416 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3417 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3417 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3418 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3418 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3419 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3419 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3420 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3420 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3421 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3421 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3422 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3422 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3423 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3423 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3424 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3424 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3425 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3425 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3426 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3426 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3427 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3427 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3428 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3428 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3429 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3429 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3430 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3430 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3431 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3431 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3432 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3432 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3433 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3433 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3434 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3434 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3435 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3435 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3436 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3436 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3437 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3437 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3438 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3438 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3439 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3439 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3440 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3440 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3441 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3441 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3442 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3442 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3443 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3443 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3444 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3444 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3445 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3445 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3446 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3446 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3447 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3447 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3448 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3448 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3449 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3449 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3450 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3450 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3451 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3451 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3452 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3452 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3453 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3453 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3454 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3454 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3455 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3455 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3456 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3456 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3457 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3457 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Trp Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3458 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3458 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3459 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3459 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3460 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3460 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3461 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3461 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3462 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3462 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3463 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3463 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3464 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3464 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3465 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3465 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3466 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3466 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3467 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3467 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3468 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3468 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3469 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3469 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3470 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3470 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3471 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3471 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3472 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3472 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3473 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3473 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3474 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3474 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3475 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3475 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3476 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3476 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3477 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3477 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3478 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3478 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3479 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3479 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3480 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3480 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3481 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3481 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Ala Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3482 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3482 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3483 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3483 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3484 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3484 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3485 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3485 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3486 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3486 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3487 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3487 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3488 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3488 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3489 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3489 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3490 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3490 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3491 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3491 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3492 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3492 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3493 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3493 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Trp Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3494 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3494 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3495 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3495 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Trp Ser Leu 20 25 <210> 3496 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3496 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3497 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3497 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Val Asp Ala Ala Thr Ser Leu 20 25 <210> 3498 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3498 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3499 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3499 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Trp Ser Leu 20 25 <210> 3500 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3500 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3501 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3501 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Leu Asp Ala Ala Thr Ser Leu 20 25 <210> 3502 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3502 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3503 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3503 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Trp Ser Leu 20 25 <210> 3504 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <220> <223> C-terminus amidated <400> 3504 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25 <210> 3505 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic peptide <400> 3505 Asp Asp Pro Lys Leu Tyr Asp Lys Asp Leu Gly Ser Ala Met Gly Asp 1 5 10 15 Thr Val Val Gly Gln Met Asp Ala Ala Thr Ser Leu 20 25

Claims (71)

  1. 변형되지 않은 쿠프레독신(cupredoxin) 유래된 펩티드와 비교하여 최소한 하나의 향상된 약동학적 특성을 갖는 쿠프레독신 유래된 펩티드의 변이체 또는 유도체인 분리되고 변형된 쿠프레독신 유래된 펩티드.
  2. 청구항 1에 있어서, 최소한 하나의 향상된 약동학적 특성은 (1) 환자에서 생체내변화(biotransformation)에 대한 감소된 민감성, (2) 더욱 늦은 속도로 환자의 신체로부터 배출, (3) 3차 구조(tertiary structure)의 증가된 안정성(stability), (4) 더욱 긴 혈장 반감기(plasma half-life)로 구성된 군에서 선택되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  3. 청구항 1에 있어서, 야생형 쿠프레독신의 최소한 하나의 약리 활성을 갖는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  4. 청구항 1에 있어서, (1) 포유동물 암 세포로 침입, (2) 비-암성 포유동물 세포로 침입하지 않음, (3) 전-악성 포유동물 세포로 침입, (4) 포유동물 암 세포 사멸, (5) 전-악성 포유동물 세포 사멸, (6) 포유동물 암 세포의 성장 저해, (7) HIV-1 감염 저해, (8) 말라리아-감염된 적혈구 세포의 기생충혈증 저해, (9) 에프린 신호전달 체계(ephrin signaling system) 간섭, (10) 혈관신생 저해로 구성된 군에서 선택되는 최소한 하나의 약리 활성을 갖는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  5. 청구항 1에 있어서, 녹농균(Pseudomonas aeruginosa), 포르미디움 라미노섬(Phormidium laminosum), 울바 퍼투씨스(Ulva pertussis), 티오바실루스 페로옥시단스(Thiobacillus ferrooxidans), 아크로모박터 시클로클라스테스(Achromobacter cycloclastes), 슈도모나스 시린가에(Pseudomonas syringae), 수막염균(Neisseria meningitidis), 장염 비브리오(Vibrio parahaemolyticus), 보르데텔라 브론키셉티카(Bordetella bronchiseptica), 백일해(Bordetella pertussis), 클로로플렉서스 아우란티아쿠스(Chloroflexus aurantiacus) 또는 임균(Neisseria gonorrhoeae)에서 선택되는 생물체로부터 유래되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  6. 청구항 1에 있어서, 아주린(azurin), 플라스토시아닌(plastocyanin), 루스티시아닌(rusticyanin), 슈도아주린(pseudoazurin), 아우라시아닌(auracyanin), 스텔라시아닌(stellacyanin), 오이 기초 단백질(cucumber basic protein) 또는 아주린-유사 단백질에서 선택되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  7. 청구항 6에 있어서, SEQ ID NO: 1-12로 구성된 군에서 선택되는 것을 특징으 로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  8. 청구항 1에 있어서, 쿠프레독신의 절두인 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  9. 청구항 8에 있어서, SEQ ID NO: 13-47로 구성된 군에서 선택되는 아미노산 서열을 포함하는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  10. 청구항 1에 있어서, SEQ ID NO: 1-12로 구성된 군에서 선택되는 최소한 하나의 서열과 최소한 90 % 동일한 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  11. 청구항 2에 있어서, 가수분해에 더욱 적게 민감한 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  12. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드의 서열 내에서 하나이상의 아스파라긴 또는 세린 잔기가 다른 아미노산 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  13. 청구항 12에 있어서, 아스파라긴 또는 세린 잔기가 글루타민산 또는 트레오 닌 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  14. 청구항 2에 있어서, 탈아미드화(deamidation)에 더욱 적게 민감한 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  15. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드의 하나이상의 글리신 잔기가 다른 아미노산 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  16. 청구항 15에 있어서, 하나이상의 글리신 잔기가 트레오닌 또는 알라닌 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  17. 청구항 16에 있어서, 녹농균(Pseudomonas aeruginosa) 아주린(SEQ ID NO: 1)의 잔기 58 또는 63에 동등한 쿠프레독신 유래된 펩티드 내에서 하나이상의 글리신 잔기가 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  18. 청구항 17에 있어서, SEQ ID NO: 30을 포함하는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  19. 청구항 2에 있어서, 산화에 더욱 적게 민감한 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  20. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드의 하나이상의 메티오닌 또는 시스테인 잔기가 다른 아미노산 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  21. 청구항 20에 있어서, 하나이상의 글리신 잔기가 루이신 또는 발린 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  22. 청구항 21에 있어서, 녹농균(Pseudomonas aeruginosa) 아주린(SEQ ID NO: 1)의 잔기 56 또는 64에 동등한 쿠프레독신 유래된 펩티드의 하나이상의 메티오닌 잔기가 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  23. 청구항 22에 있어서, SEQ ID NO: 31 또는 SEQ ID NO: 32를 포함하는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  24. 청구항 2에 있어서, 디켑토피페라진(diketopiperazine)과 피로글루타민산(pyroglutamic acid) 형성에 더욱 적게 민감한 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  25. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드의 N-말단으로부터 위치 1, 2 또는 3에서 글리신 잔기가 다른 아미노산 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  26. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드의 N-말단으로부터 위치 3에서 프롤린 잔기가 다른 아미노산 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  27. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드의 N-말단에서 아스파라긴 잔기가 다른 아미노산 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  28. 청구항 2에 있어서, 라세미화(racemization)에 더욱 적게 민감한 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  29. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드의 하나이상의 아미노산 잔기가 상기 아미노산 잔기의 D-이성질체로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  30. 청구항 29에 있어서, 쿠프레독신 유래된 펩티드의 전체 아미노산 잔기가 이들 아미노산 잔기의 D-이성질체로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  31. 청구항 1에 있어서, SEQ ID NO: 45를 포함하는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  32. 청구항 2에 있어서, 변성(degradation)에 더욱 적게 민감한 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  33. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드의 N-말단이 아세틸화되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  34. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드의 C-말단이 아미드화되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  35. 청구항 34에 있어서, SEQ ID NO: 33인 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  36. 청구항 2에 있어서, 3차 구조의 안정성이 증가하도록 변형되는 것을 특징으 로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  37. 청구항 36에 있어서, 최소한 하나의 α-나선의 안정성이 증가하도록 변형되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  38. 청구항 1에 있어서, 글리신, 프롤린, 세린, 아스파르트산, 알라닌, 트레오닌, 발린, 글루타민, 아스파라긴, 시스테인, 히스티딘, 리신과 아르기닌으로 구성된 군에서 선택되는 쿠프레독신 유래된 펩티드의 최소한 하나의 아미노산 잔기가 루이신, 이소루이신, 페닐알라닌, 글루타민산, 티로신, 트립토판과 메티오닌으로 구성된 군에서 선택되는 아미노산 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  39. 청구항 38에 있어서, 쿠프레독신 유래된 펩티드의 치환된 잔기가 녹농균(P. aeruginosa) 아주린의 잔기 53-56, 58-64와 68-70에 동등한 잔기 내에 존재하는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  40. 청구항 38에 있어서, 녹농균(P. aeruginosa) 아주린의 잔기 57에 동등한 잔기에서 글루타민이 트립토판 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  41. 청구항 38에 있어서, 녹농균(P. aeruginosa) 아주린의 잔기 52에 동등한 잔기에서 트레오닌이 트립토판 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  42. 청구항 38에 있어서, 녹농균(P. aeruginosa) 아주린의 잔기 61에 동등한 잔기에서 트레오닌이 트립토판 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  43. 청구항 38에 있어서, 녹농균(P. aeruginosa) 아주린의 잔기 63에 동등한 잔기에서 글리신이 트립토판 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  44. 청구항 38에 있어서, SEQ ID NO: 34-44로 구성된 군에서 선택되는 아미노산 서열을 포함하는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  45. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드의 2개 이상의 리신 잔기가 i(i+4) 간격(spacing)에서 ε-(3,5-디니트로벤조일)-리신 잔기로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  46. 청구항 45에 있어서, 쿠프레독신 유래된 펩티드의 치환된 잔기가 녹농균(P. aeruginosa) 아주린의 잔기 53-56, 58-64와 68-70에 동등한 잔기 내에 존재하는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  47. 청구항 39에 있어서, 히스티딘-시스테인 또는 히스티딘-히스티딘 잔기 쌍이 i(i+4) 간격에서 쿠프레독신 유래된 펩티드 내로 치환되고, 상기 펩티드는 Cu, Zn, Cd와 Ru로 구성된 군에서 선택되는 최소한 하나의 이온을 더욱 포함하는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  48. 청구항 47에 있어서, 쿠프레독신 유래된 펩티드의 치환된 잔기가 녹농균(P. aeruginosa) 아주린의 잔기 53-56, 58-64와 68-70에 동등한 잔기 내에 존재하는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  49. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드 내에서 고유 아미노산 잔기의 하나이상의 쌍이 고유 아미노산에 상응하는 올레핀-보유 테터(olefin-bearing tether)를 포함하는 α,α-이중치환된 비-자연 아미노산으로 치환되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  50. 청구항 49에 있어서, 쿠프레독신 유래된 펩티드의 치환된 잔기가 녹농균(P. aeruginosa) 아주린의 잔기 53-56, 58-64와 68-70에 동등한 잔기 내에 존재하는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  51. 청구항 1에 있어서, 쿠프레독신 유래된 펩티드에 공유 결합된 하나이상의 PEG 분자를 보유하는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  52. 청구항 51에 있어서, 하나이상의 PEG 분자가 쿠프레독신 유래된 펩티드의 하나이상의 시스테인 잔기에 공유 결합되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  53. 청구항 52에 있어서, 하나이상의 PEG 분자가 녹농균(Pseudomonas aeruginosa) 아주린(SEQ ID NO: 1)의 아미노산 잔기 3, 6과 112로 구성된 군에서 선택되는 잔기에 동등한 하나이상의 시스테인 잔기에 공유 결합되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  54. 청구항 51에 있어서, 시스테인 잔기가 쿠프레독신 유래된 펩티드 내로 치환되고, PEG 분자에 공유 결합되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  55. 청구항 51에 있어서, 하나이상의 PEG 분자가 리신, 시스테인, 히스티딘, 아르기닌, 아스파르트산, 글루타민산, 세린, 트레오닌, 티로신, N-말단 아미노기와 C-말단 카르복실산으로 구성된 군에서 선택되는 하나이상의 부위에서 쿠프레독신 유래된 펩티드에 공유 결합되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  56. 청구항 55에 있어서, 하나이상의 리신 잔기 또는 C-말단 카르복실산이 PEG 분자에 공유 결합되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  57. 청구항 55에 있어서, 리신, 시스테인, 히스티딘, 아르기닌, 아스파르트산, 글루타민산, 세린, 트레오닌과 티로신 잔기로 구성된 군에서 선택되는 하나이상의 잔기가 쿠프레독신 유래된 펩티드 내로 치환되고, PEG 분자에 공유 결합되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  58. 청구항 51에 있어서, 쿠프레독신 유래된 펩티드의 하나이상의 아미노기가 PEG 분자에 공유 결합되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  59. 청구항 51에 있어서, 하나이상의 PEG 분자가 쿠프레독신 유래된 펩티드에 무작위로 공유 결합되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  60. 청구항 51에 있어서, 쿠프레독신 유래된 펩티드당 PEG 분자의 평균 분자량(average molecular weight)이 200 내지 100,000 달톤(dalton)인 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  61. 청구항 60에 있어서, 하나이상의 가지형 PEG 분자에 공유 결합되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  62. 청구항 61에 있어서, 가지형 PEG 분자가 50 kDa인 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  63. 청구항 60에 있어서, 하나이상의 선형 PEG 분자에 공유 결합되는 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  64. 청구항 63에 있어서, 선형 PEG 분자가 대략 5 kDa인 것을 특징으로 하는 분리되고 변형된 쿠프레독신 유래된 펩티드.
  65. 청구항 1의 분리된 펩티드 및 제약학적으로 허용되는 담체를 함유하는 제약학적 조성물.
  66. 청구항 1의 분리된 펩티드의 치료 효과량을 포유동물에 투여하는 단계를 포함하는 방법.
  67. 청구항 66에 있어서, 포유동물은 인간인 것을 특징으로 하는 방법.
  68. 아미노산 서열 X1SX2AADX3X4X5VVX6DX7X8ASGLDKDYLKPDX9(SEQ ID NO:48)를 포함하는 분리된 펩티드:
    X1은 L 또는 아세틸화된-L에서 선택되고;
    X2는 T 또는 W에서 선택되고;
    X3은 M, L 또는 V에서 선택되고;
    X4는 Q 또는 W에서 선택되고;
    X5는 G 또는 A에서 선택되고;
    X6은 T 또는 W에서 선택되고;
    X7은 G, T 또는 W에서 선택되고;
    X8은 M, L 또는 V에서 선택되고;
    X9는 D 또는 아미드화된-D에서 선택된다.
  69. 청구항 68에 있어서, 아미노산 서열 X1SX2AADX3X4X5VVX6DX7X8ASGLDKDYLKPDX9(SEQ ID NO:48)로 구성되는 것을 특징으로 하는 분리된 펩티드:
    X1은 L 또는 아세틸화된-L에서 선택되고;
    X2는 T 또는 W에서 선택되고;
    X3은 M, L 또는 V에서 선택되고;
    X4는 Q 또는 W에서 선택되고;
    X5는 G 또는 A에서 선택되고;
    X6은 T 또는 W에서 선택되고;
    X7은 G, T 또는 W에서 선택되고;
    X8은 M, L 또는 V에서 선택되고;
    X9는 D 또는 아미드화된-D에서 선택된다.
  70. 아미노산 서열 X1DPKLYDKDLGSAX2X3DX4VVX5X6X7DAAX8SX9(SEQ ID NO:49)를 포함하는 분리된 펩티드:
    X1은 D 또는 아세틸화된-D에서 선택되고;
    X2는 M, L 또는 V에서 선택되고;
    X3은 G, T 또는 W에서 선택되고;
    X4는 T 또는 W에서 선택되고;
    X5는 G 또는 A에서 선택되고;
    X6은 Q 또는 W에서 선택되고;
    X7은 M, L 또는 V에서 선택되고;
    X8은 T 또는 W에서 선택되고;
    X9는 L 또는 아미드화된-L에서 선택된다.
  71. 청구항 70에 있어서, 아미노산 서열 X1DPKLYDKDLGSAX2X3DX4VVX5X6X7DAAX8SX9(SEQ ID NO:49)로 구성되는 것을 특징으로 하는 분리된 펩티드:
    X1은 D 또는 아세틸화된-D에서 선택되고;
    X2는 M, L 또는 V에서 선택되고;
    X3은 G, T 또는 W에서 선택되고;
    X4는 T 또는 W에서 선택되고;
    X5는 G 또는 A에서 선택되고;
    X6은 Q 또는 W에서 선택되고;
    X7은 M, L 또는 V에서 선택되고;
    X8은 T 또는 W에서 선택되고;
    X9는 L 또는 아미드화된-L에서 선택된다.
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Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7381701B2 (en) 2001-02-15 2008-06-03 The Borad Of Trustees Of The University Of Illinois Compositions and methods for treating conditions related to ephrin signaling with cupredoxins
US7556810B2 (en) 2005-07-19 2009-07-07 The Board Of Trustees Of The University Of Ilinois Compositions and methods to control angiogenesis with cupredoxins
US9096663B2 (en) 2001-02-15 2015-08-04 The Board Of Trustees Of The University Of Illinois Compositions and methods for treating conditions related to ephrin signaling with cupredoxins and mutants thereof
US9434770B2 (en) 2004-10-07 2016-09-06 Tapas K Das Gupta Modified cupredoxin derived peptides
US10675326B2 (en) 2004-10-07 2020-06-09 The Board Of Trustees Of The University Of Illinois Compositions comprising cupredoxins for treating cancer
US8158574B2 (en) 2004-10-07 2012-04-17 Cdg Therapeutics, Inc. Compositions and methods to prevent cancer with cupredoxins
US9598470B2 (en) * 2004-10-07 2017-03-21 Craig W. Beattie Compositions and methods to prevent cancer by stabilizing P53 through non MDM2-mediated pathways
US9968685B2 (en) * 2004-10-07 2018-05-15 Brad N. Taylor Methods to treat cancer with cupredoxins
BRPI0515850A (pt) 2004-10-07 2008-08-12 Ananda Chakrabarty agentes de transportes derivados de cupredoxina e métodos de uso dos mesmos
CA2615617A1 (en) 2005-07-19 2007-01-25 The Board Of Trustees Of The University Of Illinois Transport agents for crossing the blood-brain barrier and into brain cancer cells, and methods of use thereof
EP2073829B1 (en) * 2006-10-05 2012-06-20 New York Blood Center, Inc. Stabilized therapeutic small helical antiviral peptides
US8937154B2 (en) 2006-10-05 2015-01-20 New York Blood Center, Inc. Stabilized therapeutic small helical antiviral peptides
CN101600728A (zh) 2006-12-04 2009-12-09 伊利诺斯大学理事会 使用铜氧还蛋白和富含CpG的DNA治疗癌症的组合物和方法
BRPI0806451A2 (pt) 2007-02-08 2014-07-15 Univ Illinois Composições e métodos para a prevenção do câncer com cupredoxinas
JP2011522796A (ja) 2008-05-06 2011-08-04 ニューヨーク ブラッド センター， インコーポレイテッド 抗ウイルス細胞透過性ペプチド
CN103937705B (zh) * 2014-03-10 2016-03-16 赵晗 一株罕见无色杆菌及其在去除重金属离子中的应用
GB201700557D0 (en) * 2017-01-12 2017-03-01 Peptinnovate Ltd Novel peptides

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827934A (en) 1988-03-08 1998-10-27 The University Of Wyoming Cytotoxic diphtheria toxin fragments
US5972899A (en) 1996-01-25 1999-10-26 New York University Apoptosis induced by Shigella IpaB
JP2002543163A (ja) * 1999-04-30 2002-12-17 スリル バイオメディカル コーポレイション 癌および前立腺疾患のための治療としての結合体
US6800437B1 (en) 1999-08-06 2004-10-05 Tibotec Bvba Method of monitoring a biological system by labeling with an apo metal binding protein
WO2002076380A2 (en) 2001-02-15 2002-10-03 The Board Of Trustees Of The University Of Illinois Cytotoxic factors for modulating cell death
US7556810B2 (en) * 2005-07-19 2009-07-07 The Board Of Trustees Of The University Of Ilinois Compositions and methods to control angiogenesis with cupredoxins
US7491394B2 (en) * 2001-02-15 2009-02-17 The Board Of Trustees Of The University Of Illinois Cytotoxic factors for modulating cell death
US7338766B2 (en) * 2001-02-15 2008-03-04 The Board Of Trustees Of The University Of Illinois Compositions and methods for treating malaria with cupredoxin and cytochrome
EP2279746B1 (en) 2002-11-15 2013-10-02 Novartis Vaccines and Diagnostics S.r.l. Surface proteins in neisseria meningitidis
CN1506375A (zh) * 2002-12-12 2004-06-23 浙江养生堂天然药物研究所有限公司 具有广谱抗肿瘤作用的细菌蛋白天青蛋白及其用途和含有其的药物组合物
US20040132966A1 (en) * 2002-12-30 2004-07-08 Miranda Leslie Philip Backbone anchored thioester and selenoester generators
WO2004093902A1 (en) * 2003-03-19 2004-11-04 The General Hospital Corporation CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONES WITH α-HELIX STABILIZERS
GB0321937D0 (en) * 2003-09-19 2003-10-22 Univ Liverpool Nanoparticle conjugates and method of production thereof
BRPI0515850A (pt) 2004-10-07 2008-08-12 Ananda Chakrabarty agentes de transportes derivados de cupredoxina e métodos de uso dos mesmos
CN101115838B (zh) * 2004-12-07 2015-08-12 莫菲西斯公司 产生和分泌修饰的肽的方法
CA2615617A1 (en) * 2005-07-19 2007-01-25 The Board Of Trustees Of The University Of Illinois Transport agents for crossing the blood-brain barrier and into brain cancer cells, and methods of use thereof

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WO2008033820A2 (en) 2008-03-20
US10590177B2 (en) 2020-03-17
US20100267608A1 (en) 2010-10-21
BRPI0715027A2 (pt) 2013-05-28
AU2007296614A1 (en) 2008-03-20
US20180319848A1 (en) 2018-11-08
SG174108A1 (en) 2011-09-29
MX2009002612A (es) 2009-12-15
US10005821B2 (en) 2018-06-26
EP2061487A4 (en) 2009-12-02
WO2008033820A8 (en) 2009-07-30
IL197501A0 (en) 2011-08-01
NO20091330L (no) 2009-06-05
CA2663188A1 (en) 2008-03-20
RU2009113562A (ru) 2010-10-20
WO2008033820A3 (en) 2008-12-18
JP2014193886A (ja) 2014-10-09
JP2010502765A (ja) 2010-01-28
CN101600447A (zh) 2009-12-09

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