KR20090045491A - 도파민, 아스코빅산 및 요산의 동시 검출이 가능한 전도성고분자 전극을 이용한 바이오센서 및 그 제조방법 - Google Patents
도파민, 아스코빅산 및 요산의 동시 검출이 가능한 전도성고분자 전극을 이용한 바이오센서 및 그 제조방법 Download PDFInfo
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- KR20090045491A KR20090045491A KR1020070111332A KR20070111332A KR20090045491A KR 20090045491 A KR20090045491 A KR 20090045491A KR 1020070111332 A KR1020070111332 A KR 1020070111332A KR 20070111332 A KR20070111332 A KR 20070111332A KR 20090045491 A KR20090045491 A KR 20090045491A
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
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- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
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Abstract
Description
Claims (7)
- 도파민(Dopamine, DA), 아스코빅산(Ascorbic acid, AA) 및 요산(Uric acid, UA)의 동시 검출이 가능한 바이오센서.
- 타이오닌을 모노머로 하여 순환전류법에 따라 전기화학적으로 전처리된 전극 면에 타이오닌 고분자를 합성하는 방법으로 제조한 전도성 고분자 전극을 이용한 바이오센서의 제조방법.
- 제 3항에 있어서,상기 전기화학적으로 전처리된 전극은 유리질 탄소(glass carbon), 금(Au) 또는 백금(Pt) 중에서 선택되는 것을 특징으로 하는 바이오센서의 제조방법.
- 제 3항 또는 제 4항에 있어서,상기 전처리는 전해질 용액으로 pH 6.0 ~ 7.0의 인산염 완충용액(PBS buffer solution)을 사용하고, 1.5 ~ 2.0 V의 전위를 300 ~ 500초 동안 적용하는 것을 특징으로 하는 바이오센서의 제조방법.
- 제 3항에 있어서,상기 전도성 고분자 전극은 상기 전처리된 전극에 1 mM 타이오닌이 함유된 pH 6.0의 인산 완충염 용액을 100 ㎷/sec.의 속도로 전극의 전압 -0.4 ~ 0.1 V 구간에서 반복 스캔하여 전극 표면에 타이오닌 고분자 박막이 형성되는 것을 특징으로 하는 바이오센서의 제조방법.
- 제 1항의 바이오센서를 이용하여 도파민(DA), 아스코빅산(AA) 및 요산(UA)를 동시에 검출하는 방법.
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KR1020070111332A KR101069310B1 (ko) | 2007-11-02 | 2007-11-02 | 도파민, 아스코빅산 및 요산의 동시 검출이 가능한 전도성고분자 전극을 이용한 바이오센서 및 그 제조방법 |
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CN101576530B (zh) * | 2009-05-21 | 2012-02-08 | 北京化工大学 | 利用石墨纳米片/Nafion复合薄膜修饰电极测定多巴胺的方法 |
KR101140049B1 (ko) * | 2010-03-23 | 2012-05-02 | 서울대학교산학협력단 | 항 신생혈관생성인자 압타머로 기능화된 극미세 전도성 고분자 나노재료를 활용한 고감응성 전계효과 트랜지스터 암진단용 바이오센서의 제조. |
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PT106522A (pt) * | 2012-09-05 | 2014-03-05 | Univ Dos Açores | Metodologia para a determinação silmultânea do ácido ascórbico e ácido úrico no plasma humano por hplc-uv |
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KR20190082599A (ko) * | 2018-01-02 | 2019-07-10 | 한국화학연구원 | Nadh 측정을 위한 바이오센서용 전극 및 그의 제조방법 |
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CN101576530B (zh) * | 2009-05-21 | 2012-02-08 | 北京化工大学 | 利用石墨纳米片/Nafion复合薄膜修饰电极测定多巴胺的方法 |
CN101726531B (zh) * | 2009-12-16 | 2012-07-04 | 厦门大学 | 体液中多巴胺的电化学检测方法 |
KR101140049B1 (ko) * | 2010-03-23 | 2012-05-02 | 서울대학교산학협력단 | 항 신생혈관생성인자 압타머로 기능화된 극미세 전도성 고분자 나노재료를 활용한 고감응성 전계효과 트랜지스터 암진단용 바이오센서의 제조. |
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WO2019135556A1 (ko) * | 2018-01-02 | 2019-07-11 | 한국화학연구원 | Nadh 측정을 위한 바이오센서용 전극 및 그의 제조방법 |
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CN114088787A (zh) * | 2021-11-17 | 2022-02-25 | 上海第二工业大学 | 一种二维铁磁性纳米复合传感电极及其制备方法和应用 |
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