KR20080108996A - 셀룰라이트 치료용 아교질분해효소 - Google Patents

셀룰라이트 치료용 아교질분해효소 Download PDF

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Publication number
KR20080108996A
KR20080108996A KR1020087022877A KR20087022877A KR20080108996A KR 20080108996 A KR20080108996 A KR 20080108996A KR 1020087022877 A KR1020087022877 A KR 1020087022877A KR 20087022877 A KR20087022877 A KR 20087022877A KR 20080108996 A KR20080108996 A KR 20080108996A
Authority
KR
South Korea
Prior art keywords
gelatinase
cellulite
purified
injected
injection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020087022877A
Other languages
English (en)
Korean (ko)
Inventor
마리 에이. 바데일멘테
알렉산더 비. 다굼
Original Assignee
더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕 filed Critical 더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕
Publication of KR20080108996A publication Critical patent/KR20080108996A/ko
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/06Preparations for care of the skin for countering cellulitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91Injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020087022877A 2006-02-22 2007-02-22 셀룰라이트 치료용 아교질분해효소 Ceased KR20080108996A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US77569006P 2006-02-22 2006-02-22
US60/775,690 2006-02-22
US11/703,269 US20070224184A1 (en) 2006-02-22 2007-02-07 Method for treating cellulite
US11/703,269 2007-02-07

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020117028099A Division KR20120006063A (ko) 2006-02-22 2007-02-22 셀룰라이트 치료용 아교질분해효소

Publications (1)

Publication Number Publication Date
KR20080108996A true KR20080108996A (ko) 2008-12-16

Family

ID=38325147

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020087022877A Ceased KR20080108996A (ko) 2006-02-22 2007-02-22 셀룰라이트 치료용 아교질분해효소
KR1020117028099A Ceased KR20120006063A (ko) 2006-02-22 2007-02-22 셀룰라이트 치료용 아교질분해효소

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020117028099A Ceased KR20120006063A (ko) 2006-02-22 2007-02-22 셀룰라이트 치료용 아교질분해효소

Country Status (19)

Country Link
US (4) US20070224184A1 (cg-RX-API-DMAC7.html)
EP (1) EP1991258B1 (cg-RX-API-DMAC7.html)
JP (5) JP5775658B2 (cg-RX-API-DMAC7.html)
KR (2) KR20080108996A (cg-RX-API-DMAC7.html)
AU (1) AU2007221225B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0708186A2 (cg-RX-API-DMAC7.html)
CA (1) CA2643171C (cg-RX-API-DMAC7.html)
DK (1) DK1991258T3 (cg-RX-API-DMAC7.html)
ES (1) ES2553184T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20151182T1 (cg-RX-API-DMAC7.html)
HU (1) HUE025918T2 (cg-RX-API-DMAC7.html)
IL (1) IL193639A (cg-RX-API-DMAC7.html)
MX (1) MX2008010767A (cg-RX-API-DMAC7.html)
NZ (1) NZ570642A (cg-RX-API-DMAC7.html)
PL (1) PL1991258T3 (cg-RX-API-DMAC7.html)
PT (1) PT1991258E (cg-RX-API-DMAC7.html)
RS (1) RS54372B1 (cg-RX-API-DMAC7.html)
SI (1) SI1991258T1 (cg-RX-API-DMAC7.html)
WO (1) WO2007100675A2 (cg-RX-API-DMAC7.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6958150B2 (en) 1994-12-15 2005-10-25 Advance Biofactures Of Curacao, N.V. Reduction of adipose tissue
AU2006206393B2 (en) * 2005-01-21 2010-04-08 The Research Foundation Of State University Of New York Methods for treating adhesive capsulitis
US20070224184A1 (en) * 2006-02-22 2007-09-27 The Research Foundation Of The State University Of New York Method for treating cellulite
WO2008008468A2 (en) * 2006-07-14 2008-01-17 Duncan Diane I Compositions and methods for fat reduction
US10071143B1 (en) 2007-05-03 2018-09-11 The Research Foundation For The State University Of New York Methods for non-surgical treatment of carpal tunnel syndrome
TWI395593B (zh) 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
EP2403523A1 (en) * 2009-03-06 2012-01-11 Halozyme, Inc. Temperature sensitive mutants of matrix metalloprotease 1 und uses thereof
JP5284239B2 (ja) * 2009-10-07 2013-09-11 株式会社メタコ スクリーン装置
FR2966734B1 (fr) 2010-10-29 2014-07-18 Max Rombi Composition comprenant au moins une enzyme proteolytique pour son utilisation pour empecher la synthese des triglycerides
ES2953560T3 (es) * 2011-10-21 2023-11-14 Endo Global Ventures Procedimiento para el tratamiento o reducción de paniculopatía fibrosclerótica edematosa
CA2861033C (en) 2012-01-12 2017-07-25 Auxilium International Holdings, Inc. Clostridium histolyticum enzymes and methods for the use thereof
WO2014066622A2 (en) 2012-10-24 2014-05-01 The Research Foundation For The State University Of New York Use of collagenase to treat glaucoma
WO2014107745A1 (en) 2013-01-07 2014-07-10 Halozyme, Inc. Metal sensitive mutants of matrix metalloproteases and uses thereof
US9744138B2 (en) 2013-03-15 2017-08-29 Biospecifics Technologies Corp. Treatment method and product for uterine fibroids using purified collagenase
US10117892B2 (en) 2013-08-29 2018-11-06 Allergan, Inc. Devices and methods for reducing the appearance of cellulite
CN103751102A (zh) 2014-01-15 2014-04-30 上海交通大学 一种胶原酶温敏水凝胶及其制备方法和应用
ES3036011T3 (en) * 2017-03-01 2025-09-11 Endo Operations Ltd Apparatus and method for assessing and treating cellulite
KR20240001279A (ko) 2017-03-28 2024-01-03 엔도 벤쳐즈 리미티드 개선된 콜라게나제 생성 방법
WO2020021330A2 (en) * 2018-07-12 2020-01-30 Endo Global Aesthetics Limited Injection techniques for the treatment of cellulite
CN113015514A (zh) * 2018-09-18 2021-06-22 恩多全球美学有限公司 用于治疗皮下脂肪团的组合物和方法
US20220305094A1 (en) * 2019-01-06 2022-09-29 Endo Global Aesthetics Limited Collagenase formulations and methods of producing the same
AU2020366008B2 (en) 2019-10-15 2025-08-28 Biospecifics Technologies Corp. Treatment of uterine fibroids using purified collagenase
WO2021108751A1 (en) * 2019-11-26 2021-06-03 Standard Of Care Corporation Hyaluronidase compositions and methods of using same to treat cellulite
WO2023218384A1 (en) * 2022-05-10 2023-11-16 Endo Global Aesthetics Limited Methods of reducing collagenase-mediated bruising in a subject having cellulite

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338300A (en) * 1981-02-05 1982-07-06 The Regents Of The University Of California Use of purified clostridial collangenase in the treatment of Peyronie's disease
US4645668A (en) * 1983-08-04 1987-02-24 Biospecifics, Nv Method for the prevention and treatment of scars with enzymes
US4524065A (en) * 1983-08-04 1985-06-18 Bio-Specifics N.V. Method for the prevention and treatment of scars with enzymes
US5393792A (en) * 1991-11-20 1995-02-28 Advance Biofactures Of Curacao, N.V. High dosage topical forms of collagenase
US5332503A (en) * 1993-04-16 1994-07-26 Baxter International Inc. Process for purifying collagenase
CA2189646C (en) * 1994-06-24 1999-05-25 Francis E. Dwulet A purified mixture of collagenases and two other proteases obtained from clostridium histolyticum
US5589171A (en) * 1994-08-22 1996-12-31 Advance Biofactures Of Curacao Treatment of Dupuytren's disease with collagenase
CA2158822C (en) * 1994-09-27 2008-12-23 Kusuki Nishioka Therapeutic agent for rheumatic disease
US6958150B2 (en) * 1994-12-15 2005-10-25 Advance Biofactures Of Curacao, N.V. Reduction of adipose tissue
US5830741A (en) * 1996-12-06 1998-11-03 Boehringer Mannheim Corporation Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease
US6086872A (en) * 1997-03-27 2000-07-11 Advance Biofactures Of Curacao, Nv Amelioration of dupuytren's disease
EP1024788A1 (en) * 1997-10-03 2000-08-09 Lavipharm Laboratories, Inc. A prolamine-plant polar lipid composition, its method of preparation and applications thereof
US6022539A (en) * 1999-06-03 2000-02-08 Advance Biofactures Of Curacao Amelioration of peyronie's disease
AU6918700A (en) * 1999-08-20 2001-03-19 Howard Murad Pharmaceutical compositions and methods for reducing the appearance of cellulite
US20070224184A1 (en) * 2006-02-22 2007-09-27 The Research Foundation Of The State University Of New York Method for treating cellulite
AU2006206393B2 (en) * 2005-01-21 2010-04-08 The Research Foundation Of State University Of New York Methods for treating adhesive capsulitis
US7811560B2 (en) * 2006-01-30 2010-10-12 Auxilium Us Holdings, Llc Compositions and methods for treating collagen-mediated diseases
JO3400B1 (ar) * 2010-09-30 2019-10-20 Ferring Bv مركب صيدلاني من كاربيتوسين
US20210169844A1 (en) * 2019-12-10 2021-06-10 Tulex Pharmaceuticals Inc. Compositions and methods for treating epilepsy, seizures and other conditions

Also Published As

Publication number Publication date
JP6853331B2 (ja) 2021-03-31
US20220249348A1 (en) 2022-08-11
JP2016204396A (ja) 2016-12-08
CA2643171A1 (en) 2007-09-07
AU2007221225B2 (en) 2010-02-11
WO2007100675A3 (en) 2007-11-15
US10123959B2 (en) 2018-11-13
PL1991258T3 (pl) 2016-04-29
JP2015134840A (ja) 2015-07-27
HRP20151182T1 (hr) 2016-01-01
EP1991258A2 (en) 2008-11-19
WO2007100675A2 (en) 2007-09-07
JP5775658B2 (ja) 2015-09-09
BRPI0708186A2 (pt) 2011-05-24
EP1991258B1 (en) 2015-08-12
JP6649449B2 (ja) 2020-02-19
IL193639A (en) 2015-01-29
SI1991258T1 (sl) 2016-02-29
US20160279046A1 (en) 2016-09-29
NZ570642A (en) 2012-03-30
HUE025918T2 (en) 2016-05-30
ES2553184T3 (es) 2015-12-04
JP2009527570A (ja) 2009-07-30
JP6498167B2 (ja) 2019-04-10
RS54372B1 (sr) 2016-04-28
PT1991258E (pt) 2015-11-24
JP2020015771A (ja) 2020-01-30
KR20120006063A (ko) 2012-01-17
AU2007221225A1 (en) 2007-09-07
DK1991258T3 (en) 2015-11-16
CA2643171C (en) 2018-10-02
MX2008010767A (es) 2008-09-01
US20070224184A1 (en) 2007-09-27
US20190053995A1 (en) 2019-02-21
JP2018199733A (ja) 2018-12-20
IL193639A0 (en) 2011-08-01

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