KR20080079302A - 핵 형태에 기초하여 종양 줄기 세포를 식별 및 타겟팅하는방법 - Google Patents

핵 형태에 기초하여 종양 줄기 세포를 식별 및 타겟팅하는방법 Download PDF

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KR20080079302A
KR20080079302A KR1020087016673A KR20087016673A KR20080079302A KR 20080079302 A KR20080079302 A KR 20080079302A KR 1020087016673 A KR1020087016673 A KR 1020087016673A KR 20087016673 A KR20087016673 A KR 20087016673A KR 20080079302 A KR20080079302 A KR 20080079302A
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nuclei
nucleus
bell
cells
tumor
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Korean (ko)
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윌리암 지. 틸리
엘레나 브이. 고스트제바
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메사추세츠 인스티튜트 오브 테크놀로지
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • C12N5/0695Stem cells; Progenitor cells; Precursor cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7115Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020087016673A 2005-12-09 2006-12-08 핵 형태에 기초하여 종양 줄기 세포를 식별 및 타겟팅하는방법 Withdrawn KR20080079302A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74895105P 2005-12-09 2005-12-09
US60/748,951 2005-12-09

Publications (1)

Publication Number Publication Date
KR20080079302A true KR20080079302A (ko) 2008-08-29

Family

ID=38099345

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020087016673A Withdrawn KR20080079302A (ko) 2005-12-09 2006-12-08 핵 형태에 기초하여 종양 줄기 세포를 식별 및 타겟팅하는방법

Country Status (12)

Country Link
US (1) US20090304662A1 (enExample)
EP (1) EP1963490A2 (enExample)
JP (1) JP2009518438A (enExample)
KR (1) KR20080079302A (enExample)
CN (1) CN101426903A (enExample)
AU (1) AU2006321710A1 (enExample)
BR (1) BRPI0619599A2 (enExample)
CA (1) CA2632754A1 (enExample)
IL (1) IL191746A0 (enExample)
RU (1) RU2008127844A (enExample)
WO (1) WO2007067795A2 (enExample)
ZA (1) ZA200804973B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2007101496A (ru) 2004-06-17 2008-07-27 Массачусетс Инститьют Оф Текнолоджи (Us) Способы идентификации стволовых клеток, основанные на ядерных морфотипах
CA2692072A1 (en) * 2007-06-13 2008-12-24 Massachusetts Institute Of Technology Methods and agents for inhibiting tumor growth
IT1392908B1 (it) 2008-09-29 2012-04-02 Italfarmaco Spa Uso degli inibitori delle istone-deacetilasi per la cura di sindromi mieloproliferative philadelphia-negative
US8217079B2 (en) 2010-03-26 2012-07-10 Italfarmaco Spa Method for treating Philadelphia-negative myeloproliferative syndromes
CA2815787A1 (en) 2010-10-25 2012-05-10 Massachusetts Institute Of Technology Wound healing metakaryotic stem cells and methods of use thereof
CN103890582A (zh) * 2011-06-02 2014-06-25 麻省理工学院 后核干细胞的dsRNA/DNA杂合基因组复制中间体
CN110118875B (zh) * 2019-05-09 2020-08-28 量准(武汉)生命科技有限公司 一种人类唾液中c型反应性蛋白彩色成像的方法及装置

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7361336B1 (en) * 1997-09-18 2008-04-22 Ivan Bergstein Methods of cancer therapy targeted against a cancer stem line
US6984522B2 (en) * 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
RU2007101496A (ru) * 2004-06-17 2008-07-27 Массачусетс Инститьют Оф Текнолоджи (Us) Способы идентификации стволовых клеток, основанные на ядерных морфотипах

Also Published As

Publication number Publication date
WO2007067795A3 (en) 2007-08-23
AU2006321710A1 (en) 2007-06-14
WO2007067795A2 (en) 2007-06-14
RU2008127844A (ru) 2010-02-10
IL191746A0 (en) 2008-12-29
ZA200804973B (en) 2009-11-25
JP2009518438A (ja) 2009-05-07
CA2632754A1 (en) 2007-06-14
CN101426903A (zh) 2009-05-06
EP1963490A2 (en) 2008-09-03
US20090304662A1 (en) 2009-12-10
BRPI0619599A2 (pt) 2011-10-11

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PA0105 International application

Patent event date: 20080709

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid