KR20080071193A - 위장 장애의 치료 방법 및 치료 조성물 - Google Patents

위장 장애의 치료 방법 및 치료 조성물 Download PDF

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Publication number
KR20080071193A
KR20080071193A KR1020087015231A KR20087015231A KR20080071193A KR 20080071193 A KR20080071193 A KR 20080071193A KR 1020087015231 A KR1020087015231 A KR 1020087015231A KR 20087015231 A KR20087015231 A KR 20087015231A KR 20080071193 A KR20080071193 A KR 20080071193A
Authority
KR
South Korea
Prior art keywords
guanosine
cyclic
pharmaceutically acceptable
diarrhea
monophosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020087015231A
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English (en)
Korean (ko)
Inventor
마크 지. 커리
Original Assignee
아이언우드 파마슈티컬스, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아이언우드 파마슈티컬스, 인코포레이티드 filed Critical 아이언우드 파마슈티컬스, 인코포레이티드
Publication of KR20080071193A publication Critical patent/KR20080071193A/ko
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A61K31/708Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/664Amides of phosphorus acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
KR1020087015231A 2005-11-23 2006-11-22 위장 장애의 치료 방법 및 치료 조성물 Ceased KR20080071193A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73949105P 2005-11-23 2005-11-23
US60/739,491 2005-11-23

Publications (1)

Publication Number Publication Date
KR20080071193A true KR20080071193A (ko) 2008-08-01

Family

ID=38067930

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020087015231A Ceased KR20080071193A (ko) 2005-11-23 2006-11-22 위장 장애의 치료 방법 및 치료 조성물

Country Status (15)

Country Link
US (2) US20090233882A1 (enExample)
EP (1) EP1957509A4 (enExample)
JP (1) JP2009517391A (enExample)
KR (1) KR20080071193A (enExample)
CN (2) CN102342953A (enExample)
AU (1) AU2006318429A1 (enExample)
BR (1) BRPI0618859A2 (enExample)
CA (1) CA2630241A1 (enExample)
EA (1) EA200801408A1 (enExample)
IL (1) IL191537A0 (enExample)
MX (1) MX2008006550A (enExample)
NO (1) NO20082758L (enExample)
NZ (1) NZ568400A (enExample)
WO (1) WO2007062168A2 (enExample)
ZA (1) ZA200804500B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012099350A3 (ko) * 2011-01-18 2012-12-06 한국기계연구원 상온진공과립분사 공정을 위한 취성재료 과립 및 이를 이용한 코팅층의 형성방법
CN103501888A (zh) * 2011-01-18 2014-01-08 韩国机械研究院 室温真空颗粒喷射的脆性材料颗粒及其形成涂膜的方法
KR102049881B1 (ko) * 2018-07-16 2019-11-28 충북대학교 산학협력단 파인애플박 및 페퍼민트 에센셜 오일을 유효성분으로 포함하는 돼지의 위궤양 개선 또는 예방용 사료첨가제 조성물
KR20220074636A (ko) * 2020-11-27 2022-06-03 한국생명공학연구원 dcGMP를 유효성분으로 포함하는 면역 증강용 조성물

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10543207B2 (en) 2008-12-31 2020-01-28 Ardelyx, Inc. Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
EP2934495B1 (en) * 2012-12-21 2017-07-19 National Health Research Institutes Mesoporous silica nanoparticles for oil absorption
US11911361B2 (en) 2014-05-29 2024-02-27 Radius Pharmaceuticals, Inc. Stable cannabinoid formulations
US11331279B2 (en) 2014-05-29 2022-05-17 Radius Pharmaceuticals, Inc. Stable cannabinoid formulations
EP3481842A1 (en) 2016-07-11 2019-05-15 Mireca Medicines GmbH New equatorially modified polymer linked multimers of guanosine-3', 5'-cyclic monophosphates
JP2020517727A (ja) * 2017-04-27 2020-06-18 インシス・ディベロップメント・カンパニー・インコーポレイテッド 安定なカンナビノイド製剤
CN111803484B (zh) * 2020-09-04 2021-08-17 郑州大学 奥替溴铵在制备抗肿瘤药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2007350A6 (es) * 1987-05-29 1989-06-16 Ganadera Union Ind Agro Productos alimenticios enriquecidos con nucleosidos yno nucleotidos para la nutricion infantil y de adultos, y procedimiento para su preparacion.
KR19990014865A (ko) * 1995-05-17 1999-02-25 피터 이. 브래이브맨 소장에서의 소화 및 흡수를 증진시키기 위한, 지방산을 함유한조성물들
US20040192638A1 (en) * 2001-07-02 2004-09-30 Oaks John A. Method and composition for prolonging the residence time of drugs in the gut
US7304036B2 (en) * 2003-01-28 2007-12-04 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders
WO2005074575A2 (en) * 2004-01-30 2005-08-18 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012099350A3 (ko) * 2011-01-18 2012-12-06 한국기계연구원 상온진공과립분사 공정을 위한 취성재료 과립 및 이를 이용한 코팅층의 형성방법
CN103501888A (zh) * 2011-01-18 2014-01-08 韩国机械研究院 室温真空颗粒喷射的脆性材料颗粒及其形成涂膜的方法
KR101380836B1 (ko) * 2011-01-18 2014-04-09 한국기계연구원 상온진공과립분사 공정을 위한 취성재료 과립 및 이를 이용한 코팅층의 형성방법
KR102049881B1 (ko) * 2018-07-16 2019-11-28 충북대학교 산학협력단 파인애플박 및 페퍼민트 에센셜 오일을 유효성분으로 포함하는 돼지의 위궤양 개선 또는 예방용 사료첨가제 조성물
KR20220074636A (ko) * 2020-11-27 2022-06-03 한국생명공학연구원 dcGMP를 유효성분으로 포함하는 면역 증강용 조성물

Also Published As

Publication number Publication date
BRPI0618859A2 (pt) 2011-09-13
NZ568400A (en) 2011-11-25
US20090233882A1 (en) 2009-09-17
MX2008006550A (es) 2008-09-23
AU2006318429A1 (en) 2007-05-31
WO2007062168A3 (en) 2007-12-06
JP2009517391A (ja) 2009-04-30
EA200801408A1 (ru) 2008-12-30
CA2630241A1 (en) 2007-05-31
CN101360756A (zh) 2009-02-04
US20120172325A1 (en) 2012-07-05
ZA200804500B (en) 2009-08-26
EP1957509A2 (en) 2008-08-20
NO20082758L (enExample) 2008-08-22
CN102342953A (zh) 2012-02-08
IL191537A0 (en) 2008-12-29
EP1957509A4 (en) 2010-10-27
WO2007062168A2 (en) 2007-05-31

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