KR20080036694A - Invention of crude cosmetic composition for anti-oxidative, bacterial activity, wrinkle, aging - Google Patents
Invention of crude cosmetic composition for anti-oxidative, bacterial activity, wrinkle, aging Download PDFInfo
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- KR20080036694A KR20080036694A KR1020060103224A KR20060103224A KR20080036694A KR 20080036694 A KR20080036694 A KR 20080036694A KR 1020060103224 A KR1020060103224 A KR 1020060103224A KR 20060103224 A KR20060103224 A KR 20060103224A KR 20080036694 A KR20080036694 A KR 20080036694A
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract
Description
도1은 본발명의 실시예에 따른 원료의 추출방식의 제조 공정도.1 is a manufacturing process of the extraction method of the raw material according to an embodiment of the present invention.
도2는 본발명의 실시예에 따른 원료와 화장조성물의 제조 공정도.Figure 2 is a manufacturing process of the raw material and the cosmetic composition according to an embodiment of the present invention.
본 발명은 항산화, 항균, 주름개선, 미백, 보습, 노화방지의 활성을 갖는 감잎, 지실, 녹두, 애엽, 유근피, 빈랑자, 당귀, 박하, 감초, 다시마, 백지,상지, 천궁, 은행, 어성초, 대추, 인삼, 녹차, 표고버섯을 포함하는 혼합 생약추출물을 함유하는 조성물에 관한 것이다.The present invention is an antioxidant, antibacterial, anti-wrinkle, whitening, moisturizing, persimmon leaf having anti-aging activity, fruit, green bean, young leaf, root root, betel nut, Angelica, peppermint, licorice, kelp, white paper, upper limb, Cheongung, ginkgo, eoseongcho It relates to a composition containing a mixed herbal extract, jujube, ginseng, green tea, shiitake mushrooms.
피부는 나이가 들어감에 따라 주름이 증가하고 위축ㅇ 퇴행되며 건조하고 거칠어진다. 털의 모주기는 변하고 눈썹, 치모 등이 길어지고, 머리털은 짧아진다. 손톱도 거칠어지고, 백색이 되고, 피부가 늘어져 만곡도 생기게된다. As the skin ages, the wrinkles increase, the atrophy degenerates, and the skin becomes dry and rough. The hair cycle of the hair changes, the eyebrows and pubic hair become longer, and the hair shortens. Nails also become rough, white, and the skin stretches, creating curvature.
노인들의 피부 노화 현상은 피하 지방층의 분로의 변화로 얼굴이나 어깨 하지에서 는 지방층이 소실되고 엉덩이나 복부로 침착되어 피하 지방층이 감소하고 수분이 손실되며, 탄력 섬유의 상실과 침착으로 유발된다. 피부노화의 징후는 다음과 같다. Aging of the skin in the elderly is a change in the subcutaneous fat layer shunt, loss of fat layer in the lower face and shoulders, deposited in the buttocks or abdomen, reducing the subcutaneous fat layer, loss of moisture, caused by loss of elastic fibers and deposition. The signs of skin aging are:
1.피부의 주름이 증가한다.1. Wrinkles on the skin increase.
2.피부가 이완한다.2. The skin relaxes.
3.피부의 광택, 윤기, 매끄럼움이 저하한다.3. The gloss, gloss and smoothness of the skin decreases.
4.피부의 살결이 거칠어지고, 피구가 흐트러진다.4. The skin texture becomes rough, and the dodgeball is disturbed.
5.색소침착반점이 증가하고 사람에 따라 부분적인 탈색반점이 생긴다.5. Pigmentation spots increase and some people have partial bleaching spots.
6.피부가 황색을 띤다.6. Skin is yellowish.
7.두발이 감소하고, 탄력이 없어진다.7. The hair is reduced, the elasticity is lost.
8.두발이 벗겨진다.8. Your hair comes off.
9.백발이 증가한다.9.White hair increases.
10.눈썹이나 귓털이 길어진다.10. Long eyebrows and hairs.
11.손톱이 거칠어진다.11. Nails are rough.
(실버세대 화장품 사용실태에 관한연구 한은영 p 36~ 37. 2004)(Study on the Use Status of Silver Generation Cosmetics Eun Young Han p 36 ~ 37. 2004)
피부의 노화는 내적노화와 외적노화로 분류할 수 있는데 외부적인요인은 어느 정도 조절이 가능하다고 할 수 있다. 활성산소, 자외선 및 콜라겐의 생합성 감소 등은 대표적인 주름형성의 인자로서, 이러한 외부요인들은 활성산소의 제거 및 콜라겐의 생합성의 촉진을 통해 주름을 완화하는 것으로 알려져 있다. 또한 멜라노사이트라는 기저층에 존재하는 색소세포를 자극하여 멜라닌을 합성하는데 이런 멜라닌은 기 미 및 주근깨을 생성한다. Arbutin, Kojic Acid, Tropolone, Hydroquinone, melanostatinemddl등이 여성의 기미치유에 사용되고 있으나 안정성 및 효과에 있어 소비자를 만족시키지 못하여, 최근 한방자원을 이용한 천연 자원의 추출을 통하여 이러한 타이로시나제의 저해능력이 뛰어난 물질을 이용하려고 노력하고 있다. Skin aging can be classified into internal aging and external aging, and external factors can be controlled to some extent. Reducing the biosynthesis of free radicals, ultraviolet rays and collagen are representative factors for wrinkle formation, and these external factors are known to alleviate wrinkles by removing free radicals and promoting collagen biosynthesis. It also stimulates pigment cells present in the basal layer called melanocytes to synthesize melanin, which produces melanoma and freckles. Arbutin, Kojic Acid, Tropolone, Hydroquinone, melanostatinemddl, etc. are used in women's blemish healing, but they do not satisfy consumers in stability and effectiveness. Recently, the inhibitory ability of tyrosinase through the extraction of natural resources using herbal resources I'm trying to use excellent materials.
항산화활성이란 생체 내 활성산소의 생성을 방지하고 세포에 회복 불가능한 손상을 야기하는 산황현상을 방지하는 활성을 말한다. 안정한 상태의 산소는 효소계, 환원 대사, 화학약품, 공해물질, 광화학 반응과 같은 환경적 및 생화학적 요인 등에 의해 슈퍼옥사이드 라디칼, 하이드록실 라디칼, 과사화수소와 같은 반응성이 큰 활성 산소로 전환되어 다양한 세포 구성 성분인 지질, 단백질, DNA를 산화시켜 염증을 유발하거나 여러 기관들을 손상시킨다고 알려저 있다. 활성산소의 작용은 체내 방어기구인 슈퍼옥사이드스뮤타제(SOD), 카틸라아제,퍼옥시다아제 등의 항산화성 효고 및 비타민C, E, 글루타치온등의 항산화물질의 작용에 의하여 최소화 될 수 있으나, 이러한 생체방어력에 이상이 생기거나 과도한 활성산호에 노출될 경우 이 균형이 깨어져서 각종 질병이 유발된다는 것이 보고되었다. Antioxidant activity refers to an activity that prevents the production of free radicals in vivo and prevents sulfur phenomena causing irreparable damage to cells. Oxygen in a stable state is converted into highly reactive reactive oxygen such as superoxide radicals, hydroxyl radicals and hydrogen peroxide by various environmental and biochemical factors such as enzymes, reduction metabolism, chemicals, pollutants, and photochemical reactions. It is known to oxidize its components, lipids, proteins and DNA, causing inflammation or damaging many organs. The action of free radicals can be minimized by the action of antioxidants such as superoxide smistase (SOD), catylase and peroxidase, and antioxidants such as vitamins C, E and glutathione. It has been reported that in case of abnormalities or exposure to excessive active corals, this balance is broken and various diseases are caused.
본 발명은 항산화, 항균, 주름개선, 미백, 보습, 노화방지의 활성을 갖는 감잎, 지실, 녹두, 애엽, 유근피, 빈랑자, 당귀, 박하, 감초, 다시마, 백지,상지, 천궁, 은행, 어성초, 대추, 인삼, 녹차, 표고버섯을 포함하는 혼합 생약추출물을 함유하며 안정성에 문제가없는 비누 및 화장료 조성물을 제공하는것이다. The present invention is an antioxidant, antibacterial, anti-wrinkle, whitening, moisturizing, persimmon leaf having anti-aging activity, fruit, green bean, young leaf, root root, betel nut, Angelica, peppermint, licorice, kelp, white paper, upper limb, Cheongung, ginkgo, eoseongcho To provide a mixed herbal extract including jujube, ginseng, green tea, shiitake mushrooms, there is no problem in stability, and to provide a cosmetic composition.
상기 목적을 당성하기 위하여, 본 발명은 항산화, 항균, 주름개선, 보습, 미백, 노화방지 효과를 갖는 감잎, 지실, 녹두, 애엽, 유근피, 빈랑자, 당귀, 박하, 감초, 다시마, 백지,상지, 천궁, 은행, 어성초, 대추, 인삼, 녹차, 표고버섯을 포함하는 혼합생약 추출물을 함유하는 조성물을 제공한다. In order to achieve the above object, the present invention is antioxidant, antibacterial, wrinkle improvement, moisturizing, whitening, persimmon leaf, fruit, green beans, green leaf, young root, root skin, betel nut, Angelica, mint, licorice, kelp, white paper, upper limb It provides a composition containing a mixed herbal extract, including cheongung, ginkgo, eoseongcho, jujube, ginseng, green tea, shiitake mushrooms.
발명의 추출물의 혼합중량비는 감잎 1~20 : 지실 1~5 : 녹두 1~5 : 애엽 1~15: 유근피 1~15 : 빈랑자 1~5: 당귀1~5: 박하1~5: 감초1~10: 다시마 1~10 : 백지 1~5 : 상지1~5: 천궁1~10: 은행 1~5: 어성초1~5: 대추 1~20: 인삼 1~10 : 녹차 1~10 : 표고버섯 1~10, 보다 바람직하게는 감잎 1~12 : 지실 1~3 : 녹두 1~3 : 애엽 1~9 : 유근피 1~9 : 빈랑자 1~3: 당귀1~3: 박하1~3: 감초1~6: 다시마 1~9 : 백지 1~3 : 상지1~3 : 천궁1~6: 은행 1~3: 어성초1~6: 대추 1~12: 인삼 1~6 : 녹차 1~6 : 표고버섯 1~6, 더욱더 바람직하게는 감잎 1~8 : 지실 1~2 : 녹두 1~2 : 애엽 1~6 : 유근피 1~6 : 빈랑자 1~2: 당귀1~2: 박하1~2: 감초1~4: 다시마 1~6 : 백지 1~2 : 상지1~2 : 천궁1~4: 은행 1~2: 어성초1~4: 대추 1~8: 인삼 1~4 : 녹차 1~4 : 표고버섯 1~6 혼합된 것이다.Mixing weight ratio of the extract of the invention is persimmon leaf 1-20: fruit 1-5: green beans 1-5: leaf 1-15: roots 1-15: betel nut 1-5: Angelica 1-5: mint 1-5: licorice 1 ~ 10: Kelp 1 ~ 10: White paper 1 ~ 5: Sangji 1 ~ 5: Cheonggung 1 ~ 10: Bank 1 ~ 5: Eoseongcho 1 ~ 5: Jujube 1 ~ 20: Ginseng 1 ~ 10: Green tea 1 ~ 10: Shiitake mushroom 1 to 10, more preferably persimmon leaves 1 to 12: fruit room 1 to 3: green beans 1 to 3: leaf 1 to 9: roots 1 to 9: betel nut 1 to 3: donkey 1 to 3: peppermint 1 to 3: licorice 1 ~ 6: Kelp 1 ~ 9: White paper 1 ~ 3: Sangji 1 ~ 3: Cheongung 1 ~ 6: Bank 1 ~ 3: Eoseongcho 1 ~ 6: Jujube 1 ~ 12: Ginseng 1 ~ 6: Green tea 1 ~ 6: Elevation Mushrooms 1-6, even more preferably persimmon leaves 1-8: fruit room 1-2: mung beans 1 ~ 2: leafy leaves 1-6: roots 1 ~ 6: betel nut 1-2, donkey 1-2, peppermint 1-2: Licorice 1 ~ 4: Kelp 1 ~ 6: White paper 1 ~ 2: Sangji 1 ~ 2: Cheongung 1 ~ 4: Bank 1 ~ 2: Eoseongcho 1 ~ 4: Jujube 1 ~ 8: Ginseng 1 ~ 4: Green tea 1 ~ 4: Shiitake mushrooms 1-6 are mixed.
상기 추출물은 정제수를 포함한 물, 탄소수 1내지 4의 저급알코올 또는 프로필렌글리콜, 초산에칠, 부틸렌클리콜, 에텔, 클로로포름으로 구성된 그룹으로부터 선택된 하나 이상의 용매에 가용한 추출물을 포함한다. The extract includes water containing purified water, a lower alcohol having 1 to 4 carbon atoms or propylene glycol, an extract available in at least one solvent selected from the group consisting of ethyl acetate, butylene glycol, ether, chloroform.
본 발명의 추출물은 감잎, 지실, 녹두, 애엽, 유근피, 빈랑자, 당귀, 박하, 감초, 다시마, 백지,상지, 천궁, 은행, 어성초, 대추, 인삼, 녹차, 표고버섯, 바람 직하게는 감잎, 지실, 녹두, 애엽, 유근피, 빈랑자, 당귀, 박하, 감초, 다시마, 백지,상지, 천궁, 은행, 어성초, 대추, 인삼, 녹차, 표고버섯 건조중량비로 혼합한후, 추출용매로 에탄올을 1내지 30배, 바람직하게는 5내지 15배 부피량을 10내지 50˚C, 바람직하게는 실온에서 0.5 내지 48시간, 바람직하게는 20 내지 30시간 도안 냉침추출, 열수추출, 초음파 추출, 환류냉각 추출 등의 추출방법으로, 바람직하게는 냉침추출, 열수추출, 초음파 추출, 환류냉각 추출등의 추출방법으로, 바람직하게는 5내지 10배 부피량을 30 내지 100˚C, 바람직하게는 60 내지 90˚C의 추출 온도에서 0.5 내지 10시간, 바람직하게는 1 내지 5시간, 침적, 냉침추출, 열수추출, 초음파 추출, 환류냉각 추출 등의 추출방법으로, 바람직하게는 환류냉각 추출한 후 추출액을 원심분리 및 여과, 농축하여 본 발명의 추출물을 습득한다. The extract of the present invention is persimmon leaf, fruit, green beans, young leaf, root root, betel nut, Angelica, peppermint, licorice, kelp, white paper, upper lichen, cheongung, ginkgo, eoseongcho, jujube, ginseng, green tea, shiitake, preferably persimmon leaf , Fruit, green bean, leaf, root, betel nut, Angelica, peppermint, licorice, kelp, white paper, upper limb, cheongung, ginkgo, ergocho, jujube, ginseng, green tea, shiitake mushroom dry weight ratio, ethanol 1 to 30 times, preferably 5 to 15 times the volume of 10 to 50 ° C, preferably at room temperature 0.5 to 48 hours, preferably 20 to 30 hours cold extraction, hot water extraction, ultrasonic extraction, reflux cooling Extraction methods such as extraction, preferably extraction methods such as cold extraction, hot water extraction, ultrasonic extraction, reflux cooling extraction, preferably 5 to 10 times the volume of 30 to 100 ° C, preferably 60 to 90 0.5 to 10 hours at an extraction temperature of ˚C, preferably 1 to 5 hours Extraction methods such as liver, immersion, cold sediment extraction, hot water extraction, ultrasonic extraction, reflux cooling extraction, and the like, preferably, reflux cooling extraction, and then the extract is centrifuged, filtered, and concentrated to obtain the extract of the present invention.
상기 추출방법에 의해 얻어진 추출물의 전자공여능, SOD유사활성으로 확인한 항산화효과, 항균효과, 보습, 미백, 주름개선 및 노화방지 효과각 탁월하여 노인의 피부특성에 맞는 노인전용 비누 및 화장조성물로 유용하게 사용될 수 있다. Antioxidant, antibacterial, moisturizing, whitening, anti-wrinkle and anti-aging effects of electron extracting ability and SOD-like activity of extracts obtained by the extraction method are excellent and useful as elderly soaps and cosmetic compositions suitable for elderly skin characteristics. Can be used.
본 발명은 상기의 추출공정에서 얻어지는 항산화, 항균, 보습, 미백, 주름개선 및 노화방지의 활성을 나타내는 감잎, 지실, 녹두, 애엽, 유근피, 빈랑자, 당귀, 박하, 감초, 다시마, 백지,상지, 천궁, 은행, 어성초, 대추, 인삼, 녹차, 표고버섯을 포함하는 혼합생약 추출물을 함유하는 비누 및 화장료 조성물을 제공한다.The present invention is the persimmon leaf, fruit, green bean, young leaf, rose root, betel nut, Angelica, peppermint, licorice, kelp, white paper, upper limb showing the antioxidant, antibacterial, moisturizing, whitening, wrinkle improvement and anti-aging activity obtained in the extraction process It provides a soap and a cosmetic composition containing a mixed herbal extract, including cheongung, ginkgo, eoseongcho, jujube, ginseng, green tea, shiitake mushrooms.
본 발명의 조성물은 조성물 총 중량에 대하여 상기 추출물을 0.01 내지 10% 중량 백분율, 바람직하게는 0.1 내지 8% 중량 백분율, 가장 바람직하게는 0.5sowl 5% 중량 백분율로 포함한다.The composition of the present invention comprises the extract in an amount of 0.01 to 10% by weight, preferably 0.1 to 8% by weight, most preferably 0.5sowl 5% by weight, based on the total weight of the composition.
본 발명의 추출물을 포함하는 조성물은 피부의 노화방지, 항균 효과를 위한 비누, 화장품, 세안제 등에 다양하게 사용될 수 있다. 본 조성물을 첨가할 수 있는 제품으로는 크림, 로션, 스킨들의 화장품류와 폼클렌징, 비누, 기타미용액, 세안제등이 있다.The composition containing the extract of the present invention can be used in various ways, such as soaps, cosmetics, face wash for anti-aging, antibacterial effect of the skin. Products to which the composition can be added include cosmetics and foam cleansing creams, lotions, and skins, soaps, other cosmetics, and face washes.
실험재료의 준비Preparation of Experimental Materials
본실험에 사용된 약재들은 남이제약에서 구입하였으며, 구입후 세척하여 음건후 사용하였다. The medicines used in this experiment were purchased from Nami Pharm, washed after purchase and used after drying.
시료 추출물의 재료 Material of Sample Extract
1-1. 물추출물 제조1-1. Water extract manufacturing
본 발명의 구성 생약재들을 각각 감잎20g : 지실 5 : 녹두 5g : 애엽 15g: 유근피 15g : 빈랑자 5g : 당귀5g : 박하5g : 감초10g : 다시마 10g : 백지 5g : 상지5g: 천궁 10g : 은행 5g : 어성초 5g : 대추 20g : 인삼 10g : 녹차 10g : 표고버섯 10g 을 혼합하여 전체 중량의 10배의 증류수를 가하여 85ㅀC 3시간 환류냉각 추출하여 상등액과 침전물을 분리하여 3회 반복 추출하여 물 추출물을 수득한 후, 원심분리, 여과 및 농축하여 동결건조 후 냉장실에 보관하며 본 실험의 시료로 사용하였다. Each of the constituent herbs of the present invention persimmon leaf 20g: fruit 5: green beans 5g: 15 leaves: 15g Yugeunpi 15g: betel nut 5g: Angelica 5g: peppermint 5g: licorice 10g: kelp 10g: white paper 5g: upper limbs 5g: cheongung 10g: ginkgo Eoseongcho 5g: jujube 20g: ginseng 10g: green tea 10g: 10g of shiitake mushrooms, distilled water of 10 times the total weight is added, reflux-cooled extraction at 85 ㅀ C for 3 hours to separate the supernatant and sediment three times to extract the water extract After obtaining, centrifugation, filtration and concentration were lyophilized and stored in a refrigerator compartment and used as a sample of this experiment.
1-2. 에탄올 추출물의 제조 1-2. Preparation of Ethanol Extract
본 발명의 구성 생약재들을 각각 감잎20g : 지실 5 : 녹두 5g : 애엽 15g: 유근피 15g : 빈랑자 5g : 당귀5g : 박하5g : 감초10g : 다시마 10g : 백지 5g : 상지5g: 천궁 10g : 은행 5g : 어성초 5g : 대추 20g : 인삼 10g : 녹차 10g : 표고버섯 10g 을 혼합하여 전체중량의 10배의 70% 에탄올을 가하여 실온에서 24시간 침지하여 상등액과 침전물을 분리하여 상등액을 취하고, 같은방법으로 3회 반복 추출하여 에탄올 추출물을 수득한 후, 원심분리 및 여과, 농축하여 동결건조 후 냉장실에 보관하여 본실험에 사용하였다. Each of the constituent herbs of the present invention persimmon leaf 20g: fruit 5: green beans 5g: 15 leaves: 15g Yugeunpi 15g: betel nut 5g: Angelica 5g: peppermint 5g: licorice 10g: kelp 10g: white paper 5g: upper limbs 5g: cheongung 10g: ginkgo 5g: Eoseongcho 5g: jujube 20g: ginseng 10g: green tea 10g: 10g shiitake mushrooms, 10 times 70% ethanol of the total weight is added and immersed at room temperature for 24 hours to separate the supernatant and sediment to take a supernatant, 3 times in the same way Repeated extraction to obtain an ethanol extract, centrifugation, filtration and concentration, lyophilized and stored in the refrigerator to use in this experiment.
예. 스킨로션의 제조 Yes. Preparation of Skin Lotion
추출물을 사용하여 스킨을 제조하였다.The skin was prepared using the extract.
상기에서 설명한 바와 같이, 본 발명의 혼합생약 추출물을 함유하는 화장료 조성물은 전자공여능 및 SOD유사활성실험 결과 황산화 효과를 나타내며, 주름개선, 보습효과 및 미백효과를 나타내는 바 비누 및 화장료 조성물로 유용하게 이용될 수 있다. As described above, the cosmetic composition containing the mixed herbal extract of the present invention shows a sulfated effect as a result of electron donating ability and SOD-like activity test, useful as a soap and cosmetic composition bar wrinkles, moisturizing effect and whitening effect Can be used.
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KR101139373B1 (en) * | 2009-07-29 | 2012-04-27 | 김민성 | Cosmetic composition for skinwhitening and manufacturing method thereof and mask-pack containing this |
KR101272174B1 (en) * | 2013-02-01 | 2013-06-10 | 권혜숙 | Soap composition comprising bamboo-loess and manufacturing method for thereof |
KR101492196B1 (en) * | 2013-09-06 | 2015-03-05 | 주식회사 아미코스메틱 | Composition for skin whitening comprising the mixed extract of poria cocos wolf, ulmi cortex and licorice root |
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WO2018021683A1 (en) * | 2016-07-29 | 2018-02-01 | 주식회사 엘큐바이오 | Antioxidative composition containing uldavioside a compound |
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KR101139373B1 (en) * | 2009-07-29 | 2012-04-27 | 김민성 | Cosmetic composition for skinwhitening and manufacturing method thereof and mask-pack containing this |
KR101272174B1 (en) * | 2013-02-01 | 2013-06-10 | 권혜숙 | Soap composition comprising bamboo-loess and manufacturing method for thereof |
KR101492196B1 (en) * | 2013-09-06 | 2015-03-05 | 주식회사 아미코스메틱 | Composition for skin whitening comprising the mixed extract of poria cocos wolf, ulmi cortex and licorice root |
KR20170001649A (en) | 2015-06-25 | 2017-01-04 | 이정복 | Composition comprising herbal extract for improving skin wrinkle and moisturizing |
WO2018021683A1 (en) * | 2016-07-29 | 2018-02-01 | 주식회사 엘큐바이오 | Antioxidative composition containing uldavioside a compound |
KR20180013666A (en) | 2016-07-29 | 2018-02-07 | 주식회사 엘큐바이오 | Antioxidant composition comprising uldavioside A |
KR102257807B1 (en) * | 2020-03-26 | 2021-05-28 | 오한선 | Antibacterial cosmetic composition comprising a natural extract mixture |
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