KR20070114187A - 트랜스-클로미펜의 투약 방법 - Google Patents
트랜스-클로미펜의 투약 방법 Download PDFInfo
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- KR20070114187A KR20070114187A KR1020077021707A KR20077021707A KR20070114187A KR 20070114187 A KR20070114187 A KR 20070114187A KR 1020077021707 A KR1020077021707 A KR 1020077021707A KR 20077021707 A KR20077021707 A KR 20077021707A KR 20070114187 A KR20070114187 A KR 20070114187A
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- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PL211339B1 (pl) | 2001-07-09 | 2012-05-31 | Zonagen | Zastosowanie kompozycji do wytwarzania leku do leczenia niedoboru testosteronu u samców ssaków |
| US7737185B2 (en) | 2001-07-09 | 2010-06-15 | Repros Therapeutics Inc. | Methods and compositions with trans-clomiphene |
| EP1865938A4 (en) | 2005-03-22 | 2008-09-24 | Repros Therapeutics Inc | DOSAGE SCHEMES FOR TRANS-CLOMIPHENE |
| RU2467020C2 (ru) | 2006-10-31 | 2012-11-20 | Басф Се | Регулирование в способе получения абсорбирующих воду полимерных частиц в нагретой газовой фазе |
| SG185311A1 (en) * | 2007-10-16 | 2012-11-29 | Repros Therapeutics Inc | Trans-clomiphene for metabolic syndrome |
| TWI458478B (zh) * | 2008-11-07 | 2014-11-01 | Repros Therapeutics Inc | 用於代謝症候群與第２型糖尿病的反式氯米芬 |
| UA113291C2 (xx) * | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
| CA2881604C (en) * | 2011-08-09 | 2021-09-14 | Kenneth W. Adams | Use of aromatase inhibitor or estrogen blocker for increasing spermatogenesis or testosterone levels in males |
| CN106890185A (zh) * | 2012-02-14 | 2017-06-27 | 利普生物药剂公司 | 具有短半衰期的选择性雌激素受体调节剂及其用途 |
| JP2015508825A (ja) * | 2012-02-29 | 2015-03-23 | レプロス セラピューティクス インコーポレイティド | アンドロゲン欠乏症を治療するための併用療法 |
| SG11201407397WA (en) | 2012-05-31 | 2014-12-30 | Repros Therapeutics Inc | Formulations and methods for vaginal delivery of antiprogestins |
| ES2688821T3 (es) | 2012-11-02 | 2018-11-07 | Repros Therapeutics Inc. | Métodos y composiciones para tratar afecciones dependientes de la progesterona |
| WO2014070523A1 (en) * | 2012-11-02 | 2014-05-08 | Repros Therapeutics Inc. | Trans-clomiphene for use in cancer therapy |
| EP3003487A4 (en) * | 2013-06-05 | 2017-01-25 | Repros Therapeutics Inc. | Trans-clomiphene and its analogues as agents that increase bone mineral density |
| CN108883083A (zh) * | 2016-02-25 | 2018-11-23 | 艾森潘帕克制药股份有限公司 | 两种氯米芬异构体的口服剂型及使用其治疗继发性腺功能减退症的方法 |
| WO2017182097A1 (en) | 2016-04-22 | 2017-10-26 | F.I.S. - Fabbrica Italiana Sintetici S.P.A. | Process for the preparation of enclomiphene citrate having needle shaped crystal habit. |
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| US4820736A (en) * | 1987-03-20 | 1989-04-11 | Yale University | Use of clomiphene to predict fertility in a human female |
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| JPH04312522A (ja) | 1991-04-08 | 1992-11-04 | Yoshiaki Kawashima | 徐放性錠剤の製造方法 |
| US5681585A (en) | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
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| GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
| AU2638795A (en) | 1994-06-17 | 1996-01-15 | University Of Nebraska Board Of Regents | In situ gel-forming delivery vehicle for bio-affecting substances, and method of use |
| DE4435368A1 (de) * | 1994-09-22 | 1996-03-28 | Schering Ag | Verwendung von Aromatasehemmern zur Herstellung eines Arzneimittels zur Behandlung eines relativen Androgenmangels beim Mann |
| AU6824996A (en) * | 1995-08-17 | 1997-03-12 | Dyer, Alison Margaret | Controlled release products |
| US5773031A (en) * | 1996-02-27 | 1998-06-30 | L. Perrigo Company | Acetaminophen sustained-release formulation |
| IL120262A (en) * | 1996-02-28 | 2001-01-28 | Pfizer | Droloxifene and derivatives thereof for use in increasing serum testosterone levels |
| JP2002511777A (ja) | 1996-10-28 | 2002-04-16 | ゼネラル ミルズ，インコーポレイテッド | 調放性粒子の埋包およびカプセル化 |
| ATE279461T1 (de) * | 1997-04-03 | 2004-10-15 | Guilford Pharm Inc | Bioabbaubare terephthalat polyester-polyphosphat polymere, zusammensetzungen, gegenstände und verfahren für ihre herstellung und verwendung |
| US6653297B1 (en) | 1997-07-03 | 2003-11-25 | Medical College Of Hampton Roads | Control of selective estrogen receptor modulators |
| RU2200732C2 (ru) * | 1997-08-12 | 2003-03-20 | Глэксо Вэллкам Инк. | Производные трифенилэтилена, способы лечения и профилактики остеопороза, рака груди и сердечно-сосудистого заболевания |
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| US6413533B1 (en) | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
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| CA2321321A1 (en) * | 1999-09-30 | 2001-03-30 | Isotis B.V. | Polymers loaded with bioactive agents |
| US6258802B1 (en) * | 1999-10-06 | 2001-07-10 | Medical College Of Hampton Roads | Corticoid therapy |
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| US7067557B2 (en) | 2000-05-26 | 2006-06-27 | Harry Fisch | Methods of treating androgen deficiency in men using selective antiestrogens |
| JP2003534375A (ja) * | 2000-05-26 | 2003-11-18 | フィッチ，ハリー | 選択性抗エストロゲン薬を用いた男性におけるアンドロゲン欠乏症の治療法 |
| JP2004507465A (ja) * | 2000-08-11 | 2004-03-11 | ワイス | エストロゲン受容体陽性癌腫の治療方法 |
| US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
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| PL211339B1 (pl) * | 2001-07-09 | 2012-05-31 | Zonagen | Zastosowanie kompozycji do wytwarzania leku do leczenia niedoboru testosteronu u samców ssaków |
| US6645974B2 (en) * | 2001-07-31 | 2003-11-11 | Merck & Co., Inc. | Androgen receptor modulators and methods for use thereof |
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| WO2006019916A1 (en) | 2004-07-14 | 2006-02-23 | Repros Therapeutics Inc. | Trans-clomiphene for the treatment of benign prostate hypertrophy, prostate cancer, hypogonadism, elevated triglycerides and high cholesterol |
| CA2595363C (en) | 2005-02-04 | 2012-03-27 | Repros Therapeutics Inc. | Methods and materials with trans-clomiphene for the treatment of male infertility |
| AU2006213856B2 (en) * | 2005-02-11 | 2011-03-17 | Regeneron Pharmaceuticals, Inc. | Therapeutic combination of a VEGF antagonist (VEGF trap) and an anti-hypertensive agent |
| EP1865938A4 (en) | 2005-03-22 | 2008-09-24 | Repros Therapeutics Inc | DOSAGE SCHEMES FOR TRANS-CLOMIPHENE |
| BRPI0615165A2 (pt) | 2005-08-05 | 2016-09-13 | Repros Therapeutics Inc | método de tratamento de infertilidade |
| EP1829534A1 (en) | 2006-03-02 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | Use of compounds binding to the sigma receptor for the treatment of metabolic syndrome |
| SG185311A1 (en) | 2007-10-16 | 2012-11-29 | Repros Therapeutics Inc | Trans-clomiphene for metabolic syndrome |
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| EP2392322A3 (en) | 2012-02-22 |
| BRPI0609389A2 (pt) | 2010-03-30 |
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| JP2015044867A (ja) | 2015-03-12 |
| US20090215907A1 (en) | 2009-08-27 |
| RU2413508C2 (ru) | 2011-03-10 |
| AU2006227243A1 (en) | 2006-09-28 |
| WO2006102232A3 (en) | 2007-04-12 |
| CN101163467B (zh) | 2012-07-18 |
| US8519004B2 (en) | 2013-08-27 |
| EP1865938A4 (en) | 2008-09-24 |
| PL383444A1 (pl) | 2008-03-17 |
| CN101163467A (zh) | 2008-04-16 |
| JP5785680B2 (ja) | 2015-09-30 |
| JP2018024712A (ja) | 2018-02-15 |
| AU2006227243B2 (en) | 2011-10-27 |
| RU2007138867A (ru) | 2009-04-27 |
| US8247456B2 (en) | 2012-08-21 |
| EP1865938A2 (en) | 2007-12-19 |
| CA2597700A1 (en) | 2006-09-28 |
| JP6270281B2 (ja) | 2018-01-31 |
| JP2008534503A (ja) | 2008-08-28 |
| US20120309839A1 (en) | 2012-12-06 |
| MX2007010659A (es) | 2007-11-08 |
| WO2006102232A2 (en) | 2006-09-28 |
| NZ560551A (en) | 2010-02-26 |
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