AU2006227243B2 - Dosing regimes for trans-clomiphene - Google Patents
Dosing regimes for trans-clomiphene Download PDFInfo
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- AU2006227243B2 AU2006227243B2 AU2006227243A AU2006227243A AU2006227243B2 AU 2006227243 B2 AU2006227243 B2 AU 2006227243B2 AU 2006227243 A AU2006227243 A AU 2006227243A AU 2006227243 A AU2006227243 A AU 2006227243A AU 2006227243 B2 AU2006227243 B2 AU 2006227243B2
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- Prior art keywords
- clomiphene
- testosterone
- treatment
- trans
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- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
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- Reproductive Health (AREA)
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- Rheumatology (AREA)
- Gynecology & Obstetrics (AREA)
- Neurology (AREA)
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- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/US2006/010022 WO2006102232A2 (en) | 2005-03-22 | 2006-03-17 | Dosing regimes for trans-clomiphene |
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| AU2006227243B2 true AU2006227243B2 (en) | 2011-10-27 |
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| EP (2) | EP1865938A4 (https=) |
| JP (3) | JP5785680B2 (https=) |
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| RU (1) | RU2413508C2 (https=) |
| WO (1) | WO2006102232A2 (https=) |
| ZA (1) | ZA200707774B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
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| PL211339B1 (pl) | 2001-07-09 | 2012-05-31 | Zonagen | Zastosowanie kompozycji do wytwarzania leku do leczenia niedoboru testosteronu u samców ssaków |
| US7737185B2 (en) | 2001-07-09 | 2010-06-15 | Repros Therapeutics Inc. | Methods and compositions with trans-clomiphene |
| EP1865938A4 (en) | 2005-03-22 | 2008-09-24 | Repros Therapeutics Inc | DOSAGE SCHEMES FOR TRANS-CLOMIPHENE |
| RU2467020C2 (ru) | 2006-10-31 | 2012-11-20 | Басф Се | Регулирование в способе получения абсорбирующих воду полимерных частиц в нагретой газовой фазе |
| SG185311A1 (en) * | 2007-10-16 | 2012-11-29 | Repros Therapeutics Inc | Trans-clomiphene for metabolic syndrome |
| TWI458478B (zh) * | 2008-11-07 | 2014-11-01 | Repros Therapeutics Inc | 用於代謝症候群與第２型糖尿病的反式氯米芬 |
| UA113291C2 (xx) * | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
| CA2881604C (en) * | 2011-08-09 | 2021-09-14 | Kenneth W. Adams | Use of aromatase inhibitor or estrogen blocker for increasing spermatogenesis or testosterone levels in males |
| CN106890185A (zh) * | 2012-02-14 | 2017-06-27 | 利普生物药剂公司 | 具有短半衰期的选择性雌激素受体调节剂及其用途 |
| JP2015508825A (ja) * | 2012-02-29 | 2015-03-23 | レプロス セラピューティクス インコーポレイティド | アンドロゲン欠乏症を治療するための併用療法 |
| SG11201407397WA (en) | 2012-05-31 | 2014-12-30 | Repros Therapeutics Inc | Formulations and methods for vaginal delivery of antiprogestins |
| ES2688821T3 (es) | 2012-11-02 | 2018-11-07 | Repros Therapeutics Inc. | Métodos y composiciones para tratar afecciones dependientes de la progesterona |
| WO2014070523A1 (en) * | 2012-11-02 | 2014-05-08 | Repros Therapeutics Inc. | Trans-clomiphene for use in cancer therapy |
| EP3003487A4 (en) * | 2013-06-05 | 2017-01-25 | Repros Therapeutics Inc. | Trans-clomiphene and its analogues as agents that increase bone mineral density |
| CN108883083A (zh) * | 2016-02-25 | 2018-11-23 | 艾森潘帕克制药股份有限公司 | 两种氯米芬异构体的口服剂型及使用其治疗继发性腺功能减退症的方法 |
| WO2017182097A1 (en) | 2016-04-22 | 2017-10-26 | F.I.S. - Fabbrica Italiana Sintetici S.P.A. | Process for the preparation of enclomiphene citrate having needle shaped crystal habit. |
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2006
- 2006-03-17 EP EP06738985A patent/EP1865938A4/en not_active Ceased
- 2006-03-17 RU RU2007138867/15A patent/RU2413508C2/ru active
- 2006-03-17 CN CN2006800089841A patent/CN101163467B/zh not_active Expired - Fee Related
- 2006-03-17 WO PCT/US2006/010022 patent/WO2006102232A2/en not_active Ceased
- 2006-03-17 US US11/815,542 patent/US8247456B2/en not_active Expired - Fee Related
- 2006-03-17 NZ NZ560551A patent/NZ560551A/en not_active IP Right Cessation
- 2006-03-17 AU AU2006227243A patent/AU2006227243B2/en not_active Ceased
- 2006-03-17 EP EP11153365A patent/EP2392322A3/en not_active Withdrawn
- 2006-03-17 CA CA002597700A patent/CA2597700A1/en not_active Abandoned
- 2006-03-17 JP JP2008503069A patent/JP5785680B2/ja not_active Expired - Fee Related
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- 2006-03-17 MX MX2007010659A patent/MX2007010659A/es active IP Right Grant
- 2006-03-17 PL PL383444A patent/PL383444A1/pl unknown
- 2006-03-17 KR KR1020077021707A patent/KR20070114187A/ko not_active Ceased
- 2006-03-17 CA CA3071412A patent/CA3071412A1/en not_active Abandoned
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2007
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2014
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2017
- 2017-11-17 JP JP2017221743A patent/JP2018024712A/ja active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20040097597A1 (en) * | 2001-07-09 | 2004-05-20 | Zonagen, Inc. | Methods and compositions with trans-clomiphene |
| WO2006019916A1 (en) * | 2004-07-14 | 2006-02-23 | Repros Therapeutics Inc. | Trans-clomiphene for the treatment of benign prostate hypertrophy, prostate cancer, hypogonadism, elevated triglycerides and high cholesterol |
| WO2006084153A2 (en) * | 2005-02-04 | 2006-08-10 | Repros Therapeutics Inc. | Methods and materials with trans-clomiphene for the treatment of male infertility |
Also Published As
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| HK1119070A1 (en) | 2009-02-27 |
| EP2392322A3 (en) | 2012-02-22 |
| BRPI0609389A2 (pt) | 2010-03-30 |
| ZA200707774B (en) | 2009-09-30 |
| EP2392322A2 (en) | 2011-12-07 |
| CA3071412A1 (en) | 2006-09-28 |
| JP2015044867A (ja) | 2015-03-12 |
| US20090215907A1 (en) | 2009-08-27 |
| RU2413508C2 (ru) | 2011-03-10 |
| AU2006227243A1 (en) | 2006-09-28 |
| WO2006102232A3 (en) | 2007-04-12 |
| KR20070114187A (ko) | 2007-11-29 |
| CN101163467B (zh) | 2012-07-18 |
| US8519004B2 (en) | 2013-08-27 |
| EP1865938A4 (en) | 2008-09-24 |
| PL383444A1 (pl) | 2008-03-17 |
| CN101163467A (zh) | 2008-04-16 |
| JP5785680B2 (ja) | 2015-09-30 |
| JP2018024712A (ja) | 2018-02-15 |
| RU2007138867A (ru) | 2009-04-27 |
| US8247456B2 (en) | 2012-08-21 |
| EP1865938A2 (en) | 2007-12-19 |
| CA2597700A1 (en) | 2006-09-28 |
| JP6270281B2 (ja) | 2018-01-31 |
| JP2008534503A (ja) | 2008-08-28 |
| US20120309839A1 (en) | 2012-12-06 |
| MX2007010659A (es) | 2007-11-08 |
| WO2006102232A2 (en) | 2006-09-28 |
| NZ560551A (en) | 2010-02-26 |
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