KR20070109778A - Bathing composition comprising a functional mixture - Google Patents

Abstract

A bathing composition is provided to maintain and promote the heat-insulating and warming effects and also show excellent skin diseases therapeutic, skin moisturizing, arthritis improving, fatigue recovering, mental and physical resting, skin aging inhibitory, muscle pain decreasing, skin whitening, and wrinkle improving effects. A bathing composition comprises at least one selected from the group consisting of grass powder, collagen, glucosamine, an extract of lavender, octacosanol and placenta as an effective ingredient, wherein the content of the effective ingredients is each 1-15 parts by weight, based on total parts by weight of the composition. The composition further comprises an inorganic salt or at least one selected from the group consisting of excipient, silica and amino acid or at least one selected from the group consisting of organic acids, crude drugs, polymers, medicines, surfactants, alcohols, vitamins, perfumes and pigments.

Description

Bath composition with functional compound {BATHING COMPOSITION COMPRISING A FUNCTIONAL MIXTURE}

The present invention relates to a bath composition containing at least one selected from the group consisting of grass powder, collagen, glucosamine, lavender extract, octacosanol and placenta as an active ingredient.

Wood vinegar is an aqueous solution made by collecting or cooling the smoke generated when carbonizing oak wood in general. The wood vinegar contains various organic acids, phenols, and neutral carbonyls. Such wood vinegar is harmless to the human body and is used for improving the living environment, improving the quality of agricultural and livestock industries, horticulture industry, health drinks, and deodorants.

Collagen is a light protein that constitutes fish scales in addition to bones, cartilage, teeth, tendons, and skin of animals, and is under the action of collagenase. Collagen is synthesized mainly from glandular cells, chondrocytes, osteocytes, and myofibril cells, which are special cells in our body. Especially, about 33% of chondrocytes make up the bones of human body with chondroitin. Plays a very important role.

Glucosamine is a kind of amino sugar which is a combination of natural amino acid and sugar, and is widely distributed in nature as a component of polysaccharides such as chitin, bacterial cell wall, mucopolysaccharide constituting animal cartilage and skin. In addition, human blood or mucus contains a large amount of the protein bound to this sugar, and the cell membrane of erythrocytes has a glycolipid bound to this sugar, and is produced by hydrolyzing chitin. It is used in various foods and medicines, such as drugs for deformable arthritis and nutritional supplements.

Ravenda is a perennial herb from Lamiaceae, native to the Mediterranean, and is widely grown in England, Yugo, and France. There are more than 40 species, and representative species include English lavender, Fringe lavender, Sweet lavender, and French lavender. It stabilizes the mind and induces a good night's sleep. It is effective for pain relief from insomnia and headaches. It is effective for sunburn and skin improvement. It has sterilization, soothing, pain relief, and insect repellent effect.

Octacosanol is a type of growth hormone that was discovered in 1926 by Dr. Thomas Cark Coffen of the United States as one of the bioactive substances in wheat germ oil. It is a kind of naturally saturated higher aliphatic alcohol, including embryos such as wheat, rice, sugar cane, apples and grapes. It is contained in the back shell in a very small amount. The physiological functions of octacosanol are known for hearing, endurance, stamina improvement, quickness and cardiopulmonary function, and cholesterol control in the body. Especially, it is a type of growth hormone, which improves muscle endurance, reduces fatigue, prevents muscle pain after exercise and prevents skin aging. In addition, the effect of paying attention to skin cell regeneration and moisture retention has been confirmed.

The placenta is a generally disc-shaped organ located between the membrane (amniotic membrane) that surrounds the fetus during pregnancy and the uterus. Unlike normal organs such as the liver, kidneys, and heart, the mother during pregnancy As a temporary organ installed in the fetus (fetus) and maternal role in the role of acting for the various organs of the fetus. The main function of the placenta is the exchange of material between the mother and the fetus, through which the fetus receives nutrients from the mother and discharges waste products. In addition, the placenta exchanges oxygen and carbon dioxide for the respiratory action of the fetus, converts glucose into glycogen, which is one of the important roles of the liver, and stores it again when necessary. Converts to. On the other hand, the mother's antibodies are delivered to the fetus through the placenta, which plays an important role in immune function immediately after birth until the antibodies are made by themselves. In addition, the placenta releases various hormones necessary for maintaining pregnancy and developing the fetus, such as chorionic gonadotropin and placental lactogen.

As a component of the placenta, in addition to essential amino acids such as leucine, lysine, valine, threonine, and isoleucine, dozens of amino acids such as glycine, alanine, and arginine are contained. It is also rich in various active peptides and vitamins B1, B2, B6, B12, C, D, E, niacin and calcium, sodium, potassium, phosphorus, magnesium, zinc and iron. Alkali phosphatase, acid phosphatase, hyaluronitase and the like and sugars such as glucose, galactose, polysaccharides and glycoproteins are also included. DNA, RNA and metabolites are also included, as well as various other components. Recently, the presence of various growth factors with strong physiological effects such as nerve growth factor, liver growth factor, and coronary growth factor has also been confirmed.

Placenta therapy has been popular in Japan since the 1960s to treat modern air, soil, water pollution, harmful ingredients (pesticides, preservatives, additives, etc.) and stress-related diseases. As such, various formulations such as external preparations are being distributed. Clinically, the placenta has been shown to be effective for menopausal disorders, chronic fatigue, liver disease, skin aging, and skin care (whitening) by enhancing the natural healing power of the human body. Efficacy in attention has also been confirmed for the treatment of atopic diseases. So-called whitening cosmetics are used to remove impurities through washing, bleeding, crushing, filtration, and dialysis of human or pig placenta. Therefore, when the placenta is used as a combination agent of the bathing agent, the effective amount of the placenta physiologically active substance can be expected to have an excellent effect, especially for skin whitening, moisturizing, wrinkle improvement.

Bathing agent is a medicine used for medicinal bathing, and it is defined as an external preparation to be used in preparation of skin composition or a bath as an anti-collection or adjuvant therapy for skin disease in the Ministry of Health and Welfare. Putting bath salts such as salt and sulfur in the bath at the proper concentration will alleviate the irritation to the skin and endure long-term bathing, so you can expect the effect similar to hot spring therapy. Have

Generally, fragrances, colorings, fats and oils, natural essential oils, plant extracts, organic acids, inorganic acids, and the like are mixed with inorganic salt mixtures such as forget-me-not, borax, boric acid, sulfur, salt, and carbonate according to their purpose. It is composed of components, and its action and effects are different depending on the components to be blended. However, most of the bathing agents usually give an appropriate stimulus to the skin surface to promote blood circulation, promote fatigue and metabolism, and after bathing, salts adhere to the body surface to maintain the body for a long time.

Recently, as interest in modern people's health and skin beauty is increasing, various inorganic salts that show efficacy against symptoms such as sweat bands, eczema, athlete's foot, and itching for the purpose of treating skin diseases and improving skin health are formulated as bath raw materials. One bath composition is prepared and commercially available. However, the bath salts by inorganic salts can not expect much effect on the treatment of skin diseases such as athlete's foot, sweat band, eczema, itching, skin roughness, acne, skin care effect and fatigue recovery effect.

Therefore, the present inventors include one or more selected from collagen, grass powder, glucosamine, lavender extract, octacosanol, and placenta as an active ingredient in a conventional bath composition, arthritis improvement effect, fatigue recovery and mental and mental stability, skin aging prevention, muscle pain A new bath composition has been developed that shows the effects of reduction, skin whitening and wrinkle improvement, and skin moisturizing.

It is an object of the present invention to provide a bath composition comprising at least one selected from the group consisting of grass powder, collagen, glucosamine, lavender extract, octacosanol and placenta as active ingredients. The composition of the present invention maintains and enhances the warming and thermal effects of conventional bathing agents, and at the same time, excellent skin disease treatment effect, skin moisturizing effect, arthritis improvement effect, fatigue recovery and mental and mental stability, skin aging inhibition, muscle pain reduction, skin It has effects such as whitening, wrinkle improvement, and skin moisturizing.

The present invention relates to a bath composition comprising at least one selected from the group consisting of grass powder, collagen, glucosamine, lavender extract, octacosanol, and placenta as an active ingredient.

Preferably the content of each active ingredient in the bath composition is 1 to 15 parts by weight, based on the total weight of the composition.

More preferably, the bath composition may further include an inorganic salt.

Still more preferably the bath composition may further comprise one or more selected from the group consisting of excipients, silica and amino acids.

Bath composition according to the present invention contains at least one selected from the group consisting of grass powder, collagen, glucosamine, lavender extract, octacosanol, and placenta as an active ingredient.

Grass powder in the bath composition according to the present invention, it is preferable to use grass powder prepared by purifying the wood vinegar by the following method.

Wood vinegar is a liquid of wood that is collected by cooling the smoke that is pyrolyzed (carbonized) in the kiln when burning charcoal.

At this time, the temperature of the kiln for collecting the wood vinegar is preferably 80 ℃ to 130 ℃. When the wood is put into the kiln and the fire is heated, the moist smoke containing water vapor is initially produced. At this time, since the smoke contains excess water, it is preferable to collect the sample when the temperature of the kiln is higher than 80 ℃. When the temperature exceeds 130 ° C., blue smoke comes out, and the sticky oily tar component increases, which causes poor quality.

Cooling the smoke from the carbonization process is divided into gas and liquid, the resulting liquid is called crude wood vinegar (粗 木 酢 液).

About a quarter of the wood that is the raw material of charcoal is charcoal, and 30-40% of the weight of the charcoal is crude wood vinegar. If 100kg of wood is charcoal, about 20kg ~ 25kg of charcoal and about 8kg of crude wood vinegar are collected.

When the crude wood vinegar sampled above is left in a stable place for about 6 months, the tar component contained in the crude wood vinegar is precipitated, while the crude wood vinegar is divided into a diesel oil in the upper layer, a tar tar component in the lower layer, and wood vinegar in the middle layer. At this time, the tar component is settled at the bottom part and settles, and the light tar component is floated at the top part.

When purified by extracting the clear color of the wood vinegar, such as the tea of the middle layer to obtain a purified wood vinegar of 60-70% of crude wood vinegar. This refined herbaceous acid solution is made into a herb powder through a highly difficult purification process by known methods such as stationary method, distillation method, filtration method, activated carbon method, and freeze concentration method.

When viewed from 100 kg of wood, about 4-5 kg (about 5 L) of wood vinegar can be collected, and about 1-1.5 kg of wood vinegar can be produced.

The herbaceous powder is preferably organic acids such as formic acid, acetic acid, propionic acid, lactic acid, iso lactic acid, valerian acid, isovaleric acid, crotonic acid and isocarburonic acid; Phenols such as phenol, o.m.p-cresol, 2.4 and 3.5-kisylenol, 4-ethyl and propylene phenol, guayacol, creosol, 4-ethyl and propyl-guayacol, pyrogarol; Carbonyl compounds such as formaldehyde, acetaldehyde, propionaldehyde, isobutyl aldehyde, barrel aldehyde, isobaraldehyde, copper okisal and the like; Alcohols such as methanol, ethanol, propanol and isopropanol; Neutral components such as levogulsacon, acetol, althol, and an organic acid methyl ester; Base components such as ammonia, methylamine, dimethylamine and pyridine; Ketones; And aldehydes.

Acetic acid component of the wood powder component has a skin softening and astringent (收斂) effect, alcohol component has a bactericidal, anti-inflammatory effect, carbonic acid (particles) to activate the skin cells to prevent skin aging, antibacterial It also has antioxidant activity, which is beneficial for skin disease improvement. In addition, alcohols, ketones, and aldehydes contained in trace amounts in the grass powder play a role of enhancing the permeability and absorption into the body. Grass powder has the effect of activating skin cells while promoting toxin discharge and blood circulation in the body, and thus is particularly effective in atopic dermatitis, allergic dermatitis, and muscle pain.

Collagen in the bath composition according to the present invention as a major component constituting the skin, tendons, cartilage, muscle, bone, etc., has the function of maintaining the elasticity of the tissue, lubricating oil function of the joint, and muscle fiber production. In addition, since 80% of the human dermis is composed of collagen, skin elasticity decreases, blemishes, blotch, and fine wrinkles occur in the 40s, when collagen production is reduced. desirable.

Glucosamine in the bath composition according to the present invention is a natural amino sugar (Amino-Sugar) composed of glucose and glutamine in the human body, and is widely distributed as components of polysaccharides such as animal cartilage and mucopolysaccharide constituting the skin. Glucosamine is obtained by hydrolyzing chitin or chitosan extracted from shells of shellfish or mollusks with hydrochloric acid, or by dissolving chinosan in hydrochloric acid and hydrolyzing it with chitosanase, then separating and purifying it.

Glucosamine normalizes cartilage metabolism and stimulates the synthesis of glycosaminoglycans and pro-teoglycans, which make up the substrate of the joints, thereby relieving pain in osteoarthritis, healing tendon and ligament damage from exercise, or hay fever It is known to be effective in alleviating bursitis symptoms.

Lavenda extract of the bath composition according to the present invention is Lavendula Extracted from Officinalis , it has been used for insect repellents, wound healing agents, beauty water and perfumes. In addition, it is known to be effective in promoting labor, sedation, pain relief, deodorization, antidepressant action, detoxification, and lowering blood pressure, and is also a clinically proven substance for diversion and mental and physical stability.

In the bath composition according to the present invention, octacosanol (Octacosanol) may be made by separating octacosanol through a purification process according to a solvent fraction, by extracting a large amount of oil containing 1.2% octacosanol from oil woven in rice bran. Octacosanol is attracting attention as an essential raw material for various external cosmetics that can contribute to increasing endurance and strength by increasing the amount of glycogen, an important energy source of the human body, and anti-aging effects such as skin moisturizing and wrinkle relief. Also, Dr. Creton of the University of Illinois, USA, octacosanol as a physiologically active substance through the kind of catalytic action to increase physical strength and durability, improve quickness, improve cardiopulmonary function, regenerate skin cells, etc. Yes it has been reported. The physiological effect of wheat germ oil on humans in exercise, Charles C Thomal publisher (1972).

Placenta in the bath composition according to the present invention may be prepared as a high purity raw material through a placenta of humans or animals (pigs) by washing, bleeding, crushing, filtration, dialysis, impurities removal process. As a raw material for bathing agents, it is effective for atopic diseases, skin moisturizing and whitening, and skin aging by powerful immunomodulatory function when combined with other useful ingredients, and it is preferable to use in fine powder form to maximize body absorption. The placenta is known to be effective in maintaining the elasticity and tension of the skin by activating the fibroblasts of the dermal layer while activating the skin regeneration cycle and normalizing the skin regeneration cycle. In addition, the placenta suppresses and promotes the production of melanin pigment, moisturizes, promotes tissue metabolism, angiogenesis of connective tissue, cell proliferation and regeneration, hematopoietic action, antioxidant action, anti-inflammatory action, anti-allergic action, etc. It is effective for the prevention and improvement of blemishes and freckles. It is also effective for the treatment of atopic dermatitis and acne scars.

The content of each of the active ingredients in the bath composition according to the present invention preferably contains 1 to 15 parts by weight based on the total weight of the composition. When the amount of the active ingredient is less than 1 part by weight, it is difficult to expect a skin disease treatment effect, skin beauty effect, or fatigue recovery effect according to the present composition, and when it exceeds 15 parts by weight, it is not suitable for preparation in one use when bathing. Do.

The bath composition according to the present invention may preferably further comprise an inorganic salt. The inorganic salts according to the present invention are preferably sodium chloride, potassium chloride, ammonium chloride, sodium carbonate, calcium carbonate, magnesium carbonate, heavy magnesium carbonate, sodium bicarbonate, sodium sesquicarbonate, sodium sulfate, aluminum sulfate, magnesium sulfate, iron sulfate, sodium thiosulfate Sodium sodium sulfate, sodium nitrate, potassium nitrate, calcium nitrate, sodium phosphate, sodium polyphosphate, calcium hydrogen phosphate, sulfur, sodium sulfide, potassium sulfide, iron sulfide, calcium oxide, potassium iodide, mica powder, neutral clay, sodium silicate, At least one selected from the group consisting of sodium hydroxide, calcium hydroxide, boric acid, and potassium permanganate. More preferably, the inorganic salts are at least one selected from the group consisting of sodium hydrogen carbonate, sodium chloride, sodium carbonate, potassium chloride, dry sodium sulfate and magnesium sulfate. Herein, the content of the inorganic salts preferably contains 60 to 80 parts by weight based on the total weight of the composition. When the content of the inorganic salt is less than 60 parts by weight, it is difficult to expect the warming or thermal effect of the inorganic salts, and when the content of the inorganic salt exceeds 80 parts by weight, it is difficult to expect the therapeutic effect of the active ingredient.

In addition, the bath composition according to the invention may further comprise one or more preferably selected from the group consisting of excipients, silica and amino acids.

Here, excipients are added for molding maintenance purposes of the formulation, preferably from the group consisting of lactose, dextrin, starch, sucrose, mannitol, sorbitol, glucose, saccharose, microcrystalline cellulose, gelatin, polyvinylpyridone, and xylitol Is selected. The content of the excipient in the composition of the present invention is preferably 10 to 20 parts by weight based on the total weight of the composition. When the content of the excipient is less than 10 parts by weight, the form of the formulation becomes unstable and is added only for the purpose of maintaining the molding of the formulation. 20 parts by weight or less is appropriate.

In addition, since the silica is added as an auxiliary agent for maintaining the moisturizing and moisturizing effect of the active ingredient, it is preferable to add the silica at 5 to 10 parts by weight based on the total weight of the composition.

In addition, the amino acid is added for the purpose of skin moisturizing and blood circulation, etc., preferably selected from the group consisting of glycine, alanine, leucine, lysine, methionine, threonine, tryptophan, valine, arginine, cysteine, glutamine, histidine, proline and the like. do. Since the amino acid is also an auxiliary agent for the action of the active ingredient, it is preferable to add 1 to 5 parts by weight based on the total weight of the composition.

In addition, the bath composition according to the present invention is more preferably one selected from the group consisting of organic acids, herbal medicines, dairy components, polymers, pharmaceuticals, surfactants, alcohols, vitamins, flavors, and pigments. It may contain the above.

Preferred organic acids in the present invention are dicarboxylic acids such as succinic acid, fumaric acid, malic acid, tartaric acid, citric acid, tricarboxylic acid, amino acids, pyrrolidonecarboxylic acid and the like.

In addition, preferred herbal medicines in the present invention, for example, Gilcho, creation, baekchul, lumber, ginger powder, cinnamon, peppermint leaves, Bokyeong, larvae, triticale, hydrangea, aloe, citron, licorice, chamomile, hyungae, Cheongung , Angelica, ginseng, peony, golden, iris, white paper, dermis, persimmon powder, rosemary, peach, garlic powder, saffron, chrysanthemum, loofah, green beans, purslane, lemon, or marigold. The herbal medicines used in the present invention are dried roots, stems, leaves and flowers of each raw material and added 1 to 10 vol. Of anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms based on the dry weight, and then at room temperature or warmed. After leaching with filtration and filtration, the extract obtained by the method of concentration under reduced pressure in a water bath can be used as it is, or it can be used as a powder by dispersing in inorganic salts.

In addition, preferred oil components in the present invention are rice bran oil, olive oil, soybean oil, liquid paraffin, white petrolatum, emollient, stearyl alcohol, pine oil, lavender oil, iris oil, pine oil. , Skin oil, cinnamon oil, garlic extract, peppermint oil, terepin oil, almond oil, castor oil, ceresin oil, squalane, or mink oil.

Further, preferred polymers in the present invention are sodium carboxymethyl cellulose, dextrin, casein, egg yolk powder, skim milk powder and the like.

Preferred pharmaceuticals in the present invention are, for example, dl-menthol, l-menthol, dl-camphor, l-camphor, methyl salicylate, sodium salicylate, benzoic acid, benzoate, and the like.

In addition, the bath composition according to the present invention may include any kind of surfactant such as a cationic surfactant, an anionic surfactant, a nonionic surfactant, or an amphoteric surfactant.

In addition, preferred alcohols in the present invention are monohydric alcohols such as ethyl alcohol, isopropyl alcohol, lanolin alcohol, or the like, or propylene glycol, 1,3-butylene glycol, polyethylene glycol, sorbitol, glycerin, glucose, and sugar. And polyhydric alcohols.

In addition, the bath composition according to the present invention may further contain a bath component commonly used according to the purpose of use.

The bath composition according to the present invention can be prepared according to a general bath preparation method.

In addition, the bath composition according to the present invention can be prepared in various formulations, such as powders, granules, tablets (foamable), capsules, liquids, etc., depending on the use.

Generally, powders and granules use inorganic salt bases such as sodium bicarbonate, sodium sulfate, sodium carbonate, and sodium chloride derived from hot spring components, and the tablet is a carbonic acid gas foaming bath, and sodium sulfate, sodium bicarbonate and / or sodium carbonate. It is known that carbon dioxide is generated by the reaction of organic acids, and it is known to have a great influence on foaming depending on the liquidity upon dissolution. Liquids are used by combining glycols and fats and oils as moisturizers, and capsules can be prepared using gelatin.

Hereinafter, the present invention will be described in more detail with reference to Examples, but the present invention is not limited thereto.

Example

Example 1

To 5 g of grass powder, 21 g of sodium bicarbonate, 17 g of lactose, 5 g of potassium chloride, 13.3 g of dry sodium sulfate, 22.7 g of sodium chloride, 7.3 g of silica, 2 g of glycine, and 6.7 g of magnesium sulfate were mixed and mixed uniformly. It was prepared according to the preparation method. This was sealed-packed with the film which laminated | stacked aluminum, and stored for 6 months under the temperature of 40 degreeC, and 75% of humidity.

Example 2

To 5 g of collagen, 20 g of sodium bicarbonate, 16 g of lactose, 5 g of potassium chloride, 15.5 g of dry sodium sulfate, 26.5 g of sodium chloride, 7.3 g of silica, 2 g of glycine, and 7.5 g of magnesium sulfate were added and mixed uniformly. It was prepared according to the method. It was sealed and packaged with a laminated film of aluminum and stored for 6 months at a temperature of 40 ° C. and a humidity of 75%.

Example 3

To 5 g of highly purified glucosamine, 23 g of sodium bicarbonate, 19 g of lactose, 5 g of potassium chloride, 13.3 g of dried sodium sulfate, 21.9 g of sodium chloride, 6.9 g of silica, 3 g of glycine and 7.2 g of magnesium sulfate were added. It was prepared according to the preparation method. This was sealed-packed with the film which laminated | stacked aluminum, and stored for 6 months under the temperature of 40 degreeC, and 75% of humidity.

Example 4

To 5.5 g of lavender leaves, 21 g of sodium bicarbonate, 15.5 g of lactose, 5 g of potassium chloride, 16.5 g of dry sodium sulfate, 21.5 g of sodium chloride, 8 g of silica, 2 g of glycine, and 7.2 g of magnesium sulfate were added, followed by a general powder preparation method. Prepared. This was sealed-packed with the film which laminated | stacked aluminum, and stored for 6 months under the temperature of 40 degreeC, and 75% of humidity.

Example 5

To 4 g of grass powder, collagen, glucosamine and lavender leaves, 21 g of sodium bicarbonate, 17 g of lactose, 5 g of potassium chloride, 16.5 g of dry sodium sulfate, 26 g of sodium chloride, 8 g of silica, 2 g of glycine and 7.5 g of magnesium sulfate were added. It was prepared according to the preparation method. This was sealed-packed with the film which laminated | stacked aluminum, and stored for 6 months under the temperature of 40 degreeC, and 75% of humidity.

Example 6

5 g of octacosanol and 4 g of collagen, which are highly purified, are added with 22 g of sodium bicarbonate, 4 g of potassium chloride, 14.5 g of dry sodium sulfate, 21.5 g of sodium chloride, 4 g of glycine, 7.5 g of magnesium sulfate, and 21 g of lactose. It was prepared according to. This was sealed and packaged with a laminated film of aluminum and stored for 6 months at a temperature of 40 ° C. and a humidity of 75%.

Example 7

To 4 g of placenta of highly purified human or pig, 20 g of sodium bicarbonate, 15.6 g of lactose, 5 g of potassium chloride, 12.5 g of dry sodium sulfate, 19.9 g of sodium chloride, 7.2 g of silica, 1.5 g of glycine and 12.9 g of magnesium sulfate are added to the general powder ( It was prepared according to the preparation method of i). This was sealed-packed with the film which laminated | stacked aluminum, and stored for 6 months under the temperature of 40 degreeC, and 75% of humidity.

Example 8

To 4 g of highly purified collagen, 4 g of placenta (pork), and 5 g of grass powder, 20 g of sodium bicarbonate, 6 g of potassium chloride, 14.5 g of dry sodium sulfate, 22.5 g of sodium chloride, 6.5 g of silica, 3 g of glycine, 6.9 g of magnesium sulfate, and lactose It was prepared according to the general powder preparation method by adding 16.5 g. This was sealed-packed with the film which laminated | stacked aluminum, and stored for 6 months under the temperature of 40 degreeC, and 75% of humidity.

Comparative Example 1

25 g of sodium bicarbonate, 17 g of lactose, 5 g of potassium chloride, 13.3 g of dry sodium sulfate, 22.7 g of sodium chloride, 7.3 g of silica, 2 g of glycine, and 7.7 g of magnesium sulfate were added and mixed uniformly. Once thoroughly mixed, it was prepared according to the general powder preparation method.

Experimental Example

Experimental Example 1: Skin Disease Treatment Effect Experiment

20 test subjects in their 20s and 40s with high dermatitis such as itching and atopic dermatitis were selected as test subjects, and the bath composition was prepared in Examples 1, 8 and Comparative Example 1, respectively, after filling the bath with 200 l of water. Each sample was added for 30 g, dissolved, and bathed for 10 minutes for 1 week to measure the therapeutic effect of the present composition against skin diseases such as itching of the skin and atopic dermatitis.

In the determination method, after grading a certain grade, it was confirmed by the visual observation and bather's judgment that skin diseases such as itching of the skin and atopy were resolved. Criteria are shown in Table 1 below.

TABLE 1

Rating condition One Skin itching, atopic dermatitis, etc. do not disappear at all 2 Slightly eliminate skin itching and atopic dermatitis 3 Dermatitis such as itching and atopic dermatitis disappears considerably 4 Almost no dermatitis such as itching and atopy of the skin 5 Skin itching and atopic dermatitis disappear completely

According to the above criteria, if the grade shows a reduction rate of 4 or 5, the effect is excellent, and if it shows a reduction rate of 2 or 3, it is determined that there is no effect if the reduction rate is not shown at all, such as 1, and the experimental results are shown in Table 2, respectively. It was.

TABLE 2

Excellent effect Effect medium no effect system Example 1 8 2 0 10 people Example 8 10 0 0 10 people Comparative Example 1 0 2 8 10 people

Experimental Example 2: Skin Moisturizing and Skin Moisturizing Effect Experiment

In the same manner as in Experiment 1, Example 2, Example 6, Example 8 and Comparative Example 1 was carried out for each of the bath composition five times, the satisfaction of the skin moisturizing and skin moisturizing effect shown in Table 3 below It evaluated according to the criterion of evaluation.

TABLE 3

Rating condition One No skin moisturizing and skin moisturizing effect 2 Slightly moisturizes and moisturizes skin 3 Skin moisturizing and skin moisturizing effect 4 Excellent skin moisturizing and skin moisturizing effect 5 Excellent skin moisturizing and skin moisturizing effect

The average of five times the value measured according to the criterion is shown in Table 4 below.

TABLE 4

Skin hydration Skin shine Example 2 3.8 4.0 Example 6 4.0 4.5 Example 8 5 4.9 Comparative Example 1 One 1.2

Experimental Example 3: Arthritis Effect Experiment

In the same manner as in Experimental Example 1, the bath compositions prepared in Example 3 and Comparative Example 1 were each performed five times, and the satisfaction of the arthritis improving effect was evaluated according to the criteria shown in Table 5 below.

TABLE 5

Rating condition One No arthritis effect 2 Slightly arthritis effect 3 Significantly Arthritis Effect 4 Excellent arthritis effect 5 Very good arthritis effect

The average of five times the value measured according to the criterion is shown in Table 6 below.

TABLE 6

arthritis Example 3 4.1 Comparative Example 1 1.3

Experimental Example 4: Fatigue recovery and psychosomatic stability experiment

In the same manner as in Experiment 1, the bath compositions prepared in Examples 1-5 and Comparative Example 1 were each performed five times, and the satisfaction of fatigue recovery and psychosomatic stability was evaluated according to the criteria shown in Table 7 below. .

TABLE 7

Rating condition One No fatigue recovery and mental and physical stability 2 Fatigue recovery and mental and physical stability 3 Significantly recovers from fatigue and physical and mental stability 4 Excellent fatigue recovery and mental and physical stability 5 Excellent fatigue recovery and mental and physical stability

The average of five times the value measured according to the criterion is shown in Table 8.

TABLE 8

Fatigue Recovery Mental and physical stability Example 1 4.0 4.2 Example 2 4.2 4.5 Example 3 4.0 4.0 Example 4 4.8 4.7 Example 5 5 5 Comparative Example 1 1.2 1.7

Experimental Example 5: Skin Cell Proliferation Effect Experiment

To confirm the proliferative effect of skin cells with respect to skin aging inhibition, human normal fibroblasts were seeded in 1 well of each 96-well microplate to 1 × 10 ⁴ cells in DMEM (Dulbecco's Modified Eagle's Medium) medium for 24 hours. Incubated. After the cultivation, the bath composition prepared in Example 6, Example 8 and Comparative Example 1 was added to the medium so as to have a final concentration of 250 μl / ml, followed by further incubation for 24 hours. 10 µl each of MTT (3- (4,5-dimethylthiazol-2-yl) 2,5-diphenyl tetrazolium) was added and left for 4 hours, and then the medium portion was discarded. 100 μl of DMSO (dimethyl sulfoxide) solution was added to each well and the absorbance at 570 nm was measured with a microplate reader. The cell proliferation effect (%) was obtained from the following formula and the results are shown in Table 9 below.

Cell proliferation effect (%) = {(absorbance of experimental group-absorbance of control group) / absorbance of control group} × 100

TABLE 9

Sample (500 μl / ml) Cell proliferation effect (%) Control - Example 6 78.2 Example 8 88.9 Comparative Example 1 23.4

Experimental Example 6: Skin wrinkle improvement effect experiment

Twenty subjects with neck wrinkles in their 30s and 40s were selected as test subjects, divided into two groups, and each group was bathed with the bath composition prepared in Example 8 and Comparative Example 1, and the skin wrinkle improvement effect was evaluated. After filling the tub with 200 liters of water, 30 g of each of the bath composition prepared in Example 8 and Comparative Example 1 was added to dissolve, and the sample was bathed for 10 months for 1 month. The skin of the neck area before bathing with the bath composition was measured and the same area was re-measured one month after using the bath composition to measure the amount of skin wrinkle change. Skin wrinkles were measured in a constant temperature and humidity room with a temperature of 24 ° C. and a relative humidity of 40%. The wrinkles around the neck were made of silicone rubber using a replica, and image analysis was performed using a skin viscometer.

As a result, the average wrinkle depth of the site using the bath composition of Comparative Example 1 decreased from 35 μm to 34 μm, and the average wrinkle depth of the site using the bath composition of Example 8 decreased from 37 μm to 31 μm, which is superior to that of Comparative Example 1. It has a skin wrinkle improvement effect.

The bath composition according to the present invention contains at least one selected from the group consisting of grass powder, collagen, glucosamine, lavender extract, octacosanol, and placenta as an active ingredient in a conventional bath component to provide the warming and thermal effects of conventional bathing agents. At the same time, it has excellent skin disease treatment effect, skin moisturizing effect, arthritis improvement effect, fatigue recovery and mental and mental stability, skin aging inhibition, muscle strength and endurance improvement, skin whitening, wrinkle improvement, etc. It is characterized by having.

Claims (7)

Bath powder composition containing at least one selected from the group consisting of grass powder, collagen, glucosamine, lavender extract, octacosanol and placenta as an active ingredient. The bath composition according to claim 1, wherein the content of each active ingredient is 1 to 15 parts by weight based on the total weight of the composition. The bath composition of claim 1 further comprising an inorganic salt. The inorganic salts according to claim 3, wherein the inorganic salts are sodium chloride, potassium chloride, ammonium chloride, sodium carbonate, potassium carbonate, magnesium carbonate, magnesium carbonate, sodium bicarbonate, sodium sesquicarbonate, sodium sulfate, aluminum sulfate, magnesium sulfate, iron sulfate, sodium thiosulfate, Sodium sulfate, sodium nitrate, potassium nitrate, calcium nitrate, sodium phosphate, sodium polyphosphate, calcium hydrogen phosphate, sulfur, sodium sulfide, potassium sulfide, iron sulfide, calcium oxide, potassium iodide, mica powder, neutral white clay, sodium silicate, hydroxide At least one bath composition selected from the group consisting of sodium, calcium hydroxide, boric acid and potassium permanganate. The bath composition according to claim 3 or 4, wherein the content of the inorganic salts is 60 to 80 parts by weight based on the total weight of the composition. The bath composition of claim 1 further comprising at least one selected from the group consisting of excipients, silica and amino acids. The bath composition of claim 1, further comprising at least one selected from the group consisting of organic acids, herbal medicines, dairy ingredients, polymers, pharmaceuticals, surfactants, alcohols, vitamins, flavorings and pigments.