KR20070094802A - MyD88 동종이량체화 억제제 - Google Patents

MyD88 동종이량체화 억제제 Download PDF

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KR20070094802A
KR20070094802A KR1020077016815A KR20077016815A KR20070094802A KR 20070094802 A KR20070094802 A KR 20070094802A KR 1020077016815 A KR1020077016815 A KR 1020077016815A KR 20077016815 A KR20077016815 A KR 20077016815A KR 20070094802 A KR20070094802 A KR 20070094802A
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pro
gly
compound
mimetic
val
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파올로 까르미나띠
그라지아 갈로
니콜라 팬토
비토 루지에로
마리카 사사노
도메니코 마스트로이아니
Original Assignee
시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이.
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    • C07K5/021Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
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KR1020077016815A 2004-12-20 2005-12-16 MyD88 동종이량체화 억제제 Withdrawn KR20070094802A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04425929 2004-12-20
EP04425929.9 2004-12-20

Publications (1)

Publication Number Publication Date
KR20070094802A true KR20070094802A (ko) 2007-09-21

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KR1020077016815A Withdrawn KR20070094802A (ko) 2004-12-20 2005-12-16 MyD88 동종이량체화 억제제

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Country Link
US (1) US20080064643A1 (enExample)
EP (1) EP1828246A1 (enExample)
JP (1) JP2008524167A (enExample)
KR (1) KR20070094802A (enExample)
CN (1) CN101084240A (enExample)
AU (1) AU2005318226A1 (enExample)
BR (1) BRPI0519148A2 (enExample)
CA (1) CA2590750A1 (enExample)
MX (1) MX2007007259A (enExample)
WO (1) WO2006067091A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024096677A1 (ko) * 2022-11-03 2024-05-10 한국과학기술연구원 Tlr 신호 억제 펩타이드 및 이를 포함하는 염증성 질환의 예방 또는 치료용 조성물

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0323204D0 (en) * 2003-10-03 2003-11-05 Novartis Ag Organic compounds
CN101745094A (zh) * 2010-01-28 2010-06-23 华中科技大学同济医学院附属同济医院 MyD88拓扑类肽化合物作为免疫抑制剂在医学上的用途
WO2012047175A1 (en) 2010-10-05 2012-04-12 Kemijski inštitut Fusion polypeptides comprising tir and dimerization domain for modulation of tlr/innate immunity signaling
CN102336720B (zh) 2011-03-02 2016-01-13 华中科技大学 2-氨基噻唑衍生物及制备方法和应用
US10465247B2 (en) 2011-07-01 2019-11-05 Dana-Farber Cancer Institute, Inc. Discovery of a somatic mutation in MYD88 gene in lymphoplasmacytic lymphoma
PT3366302T (pt) * 2011-07-18 2022-03-07 Univ Kentucky Res Found Proteção de células da degeneração induzida por rna alu e inibidores para proteger as células
EP2561873A1 (de) * 2011-08-26 2013-02-27 Forschungsverbund Berlin e.V. Strukturmimetika prolinreicher Peptide und ihre Verwendung
US9707235B1 (en) 2012-01-13 2017-07-18 University Of Kentucky Research Foundation Protection of cells from degeneration and treatment of geographic atrophy
WO2013112834A1 (en) * 2012-01-25 2013-08-01 Vanderbilt University Compositions and methods for treating infections
WO2013169382A1 (en) 2012-05-07 2013-11-14 DePuy Synthes Products, LLC Methods and devices for treating intervertebral disc disease
EP2920197B1 (en) * 2012-09-26 2021-03-17 President and Fellows of Harvard College Proline-locked stapled peptides and uses thereof
WO2015038887A1 (en) 2013-09-12 2015-03-19 Dana-Farber Cancer Institute Inc. Methods for evaluating and treating waldenstrom's macroglobulinemia
WO2015085075A1 (en) 2013-12-06 2015-06-11 Dana-Farber Cancer Institute, Inc. Methods to distinguish waldenström's macroglobulinemia from igm monoclonal gammopathy of undetermined significance
AU2014361798B2 (en) 2013-12-13 2020-06-11 Dana-Farber Cancer Institute, Inc. Methods to treat lymphoplasmacytic lymphoma
EP3230300B1 (de) 2014-12-11 2021-11-24 Forschungsverbund Berlin E.V. Inhibitoren zur hemmung der tumormetastasierung
JP2019069905A (ja) * 2016-02-29 2019-05-09 国立大学法人大阪大学 組織損傷治療剤
JP2019518006A (ja) 2016-04-29 2019-06-27 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド Myd88変異型疾患における治療標的としてのhck
EP3464325A1 (en) 2016-06-07 2019-04-10 Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. Backbone cyclized inhibitory peptides of myeloid differentiation factor 88 (myd88)
KR20200064075A (ko) 2017-09-07 2020-06-05 포그 파마슈티컬스 인코포레이티드 베타-카테닌 기능을 조절하는 제제 및 이의 방법
CN112153897B (zh) * 2018-01-02 2023-02-03 拉什大学医学中心 用于治疗神经病学和其他病症的组合物和方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2446458A1 (en) 2001-05-09 2002-11-14 Yale University Toll/interleukin-1 receptor adaptor protein (tirap)
AU2002366331A1 (en) * 2001-12-17 2003-06-30 Cedars-Sinai Medical Center Treating vascular disease by inhibiting myeloid differentiation factor 88

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024096677A1 (ko) * 2022-11-03 2024-05-10 한국과학기술연구원 Tlr 신호 억제 펩타이드 및 이를 포함하는 염증성 질환의 예방 또는 치료용 조성물

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BRPI0519148A2 (pt) 2008-12-30
CN101084240A (zh) 2007-12-05
WO2006067091A1 (en) 2006-06-29
US20080064643A1 (en) 2008-03-13
CA2590750A1 (en) 2006-06-29
MX2007007259A (es) 2007-08-14
AU2005318226A1 (en) 2006-06-29
EP1828246A1 (en) 2007-09-05
JP2008524167A (ja) 2008-07-10

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