KR20070054764A - Manufacturing method of black rootlets of ginseng - Google Patents

Abstract

The present invention relates to a method for producing black ginseng and black ginseng prepared by using the same, more specifically, 20% by weight of sulfur, 20% by weight of ginseng, 20% by weight of Ogapi, 17% by weight of Macmundong, 16% by weight of Bokryeong and The present invention relates to a method for producing black ginseng containing more saponin by infiltrating red ginseng into a concentrated solution heated to 7% by weight, followed by steaming and drying at least 9 times, and a black ginseng prepared by using the same.

Black Ginseng, Steamed, Dried, Saponin, Ginseng

Description

Method of manufacturing black ginseng and black ginseng manufactured using the same {MANUFACTURING METHOD OF BLACK ROOTLETS OF GINSENG}

The present invention relates to a method for producing black ginseng and black ginseng prepared by using the same, more specifically, 20% by weight of sulfur, 20% by weight of ginseng, 20% by weight of Ogapi, 17% by weight of Macmundong, 16% by weight of Bokryeong and The present invention relates to a method for producing black ginseng containing more saponin by infiltrating red ginseng into a concentrated solution heated to 7% by weight, followed by steaming and drying at least 9 times, and a black ginseng prepared by using the same.

Korean ginseng (Panax ginseng C.A. Meyer) has long been recognized as the best medicine in herbal medicine, and the mysterious medicinal effect has been recognized as the origin of the world unmatched by other herbal medicines. It is said that our ancestors became the best traders in the East because of the mysterious effects of ginseng and red ginseng. Red ginseng and ginseng research accelerated and the international ginseng symposium was held due to the excellence of red ginseng. Red ginseng contains carbohydrates, amino acids, saponins, and fatty acids such as stearic acid, palmitic acid, and oleic acid, and the volatile substance unique to red ginseng is known as panacene. Red ginseng saponin refers to a plant component that causes continuous foaming when shaking red ginseng aqueous solution and is recognized as a substance that is involved in the efficacy of red ginseng. Ginseng and red ginseng are found in small amounts of saponin in the trunk, which accounts for about 60% of the total weight. Most saponins are known to be present in the roots, outer skin and cortex, and large ginseng contains saponin compared to small ginseng. It is confirmed that the content of saponin is less than 1.9% in the main root and 4.8% in the inner part, and the bitterness is high in saponin and high in efficacy. The total saponin content is 2.84% for 4 years and 2.19 for 6 years, showing a difference of about 30%. However, the content of saponins is jagged at 4 to 6 years, so it is not possible to determine the superiority.

The efficacy of ginseng and red ginseng certified by modern medicine has homeostatic effects, safety toxic effects, resistance enhancement, endocrine control, blood pressure control, metabolism promotion, anti-inflammatory, weakness recovery, efficiency control, nerve stability, life extension, blood vessel strengthening, hematopoiesis It is said to be a ruling medicine that controls all diseases with action, health, strength, DNA synthesis, anti-cancer, sperm promotion, anti-diabetes, and growth promotion. Ginseng having such efficacy is classified by mountain, lotus root, small and large, form, part, grade, and has a deep relationship with each other. Ginseng is divided into medicines and foods and classified according to their function and responsibility.They are used as medicines for the purpose of treatment and prevention, and processed foods with relaxed conditions are classified as foods such as ginseng tea, ginseng wine, ginseng confectionery or health supplement foods. Are managed. For the purpose of processing ginseng, undried ginseng is 80 ~ 85% of moisture, which can not be stored for a long time, and has been processed for long-term preservation such as white or red ginseng. There is a bar.

Red ginseng tea has been managed by extracting and concentrating red ginseng into extract tea using extract and powder tea using powder. Representative of red ginseng tea is extract granulated tea, which is concentrated red ginseng extract, mixed with glucose and lactose, granulated and dried, and granularly molded with sugar as a carrier, and its palatability is gradually lost due to the avoidance of sugars in modern people. have. Considering this reality, the inventors of the invention focused on the invention of red ginseng leaching tea without sugar for the sake of excellence and national interest of Korean red ginseng. In addition, the present inventors have attempted to develop a ginseng tea using the small roots of ginseng, which had been discarded due to the high content of saponin but no manufacturing method. In general, red ginseng can not elute 100% of saponin by cutting its roots and tails in water, so it has been difficult to make tea easily because ordinary people had to elute it with ethanol. There was a problem that the cost of purchasing is also very expensive.

In the present invention, the drug used as an infiltrating agent to soak red ginseng has tonic action, immune function control action, cardiac diuresis action, blood pressure lowering action and anti-inflammatory action and body protection agent, body weakness, jahan, boil, jigal, food It is effective for tastelessness and anorexia, and is effective for women with uterine bleeding, gynecological disorders, menstrual irregularities and postpartum maternal disease. Samsam has the effect of guarantee, ripening, talk and wisdom. It is used as an expectorant, tonic and fertilizer for colds and lung diseases as antitussive, expectorant and tonic. McMoon-Dong has the efficacy of Yang Yin Yun Pung, Cheongshimjeung and Yang San Sengjin, and has Jagangang, Jinhae, sputum, cardiac, hypoglycemic action and anti-inflammatory action. Bokryeong is effective in tonic, diuretic and sedative, and is used for kidney disease, cystitis and urethritis. It is effective for peptic ulcer, muscle cramps, thirst, vertigo, mental anxiety and insomnia, and inhibits contact dermatitis. Health promotes secretion of gastric juice and activates the peristalsis of the intestinal tract, which helps digestion and calms vomiting. Indicates.

The present invention is to solve the above problems of the prior art, and to provide a method for producing black ginseng that can be eluted in a larger amount of saponin by cutting off red ginseng containing a high content of saponin in water. .

The present invention provides 20% by weight of sulfur, 20% by weight of ginseng, 20% by weight of Ogapi, 17% by weight of Macmundong, 16% by weight of Bokryeong and 7% by weight of at least one solvent selected from the group consisting of water, ethanol, methanol and isopropanol. First step of steaming for 3 to 6 hours at 60 to 70 ° C., and then steaming at high pressure for about 3 to 6 hours at a temperature of 135 ° C. and heating to prepare a concentrated solution of 5 Brix; After soaking red ginseng in the concentrate for 1 night and steaming for 1 to 3 hours at 60-70 ° C in a cauldron steamer until the water content reaches 28% in 70-75 ° C ocher drying room. Two process steps of drying; Three process steps of repeating the two process steps four times again; The black ginseng, which has completed the three process steps, is steamed at a high pressure steamer at a temperature of 135 ° C. for about 3 to 6 hours, and dried at 25 to 60% water at a temperature of 60 to 70 ° C. in an elvan rock hot air dryer. ; Five process steps of repeating the above four steps four times: and six process steps of drying the black ginseng, which has completed the five process steps, to a final moisture content of 14% in a bulk dryer. It relates to a manufacturing method.

Hereinafter, a method for preparing black ginseng and the black ginseng prepared by using the same according to the present invention will be described in detail. The main technical content of the present invention is to produce black ginseng by optimally processing the ginseng with the highest content of saponin, so that ordinary people can drink ginseng tea containing high saponin even if the black ginseng is simply cut off in water.

Ginseng is divided into the main root portion corresponding to the trunk and the tail root corresponding to the root root. Generally, the content of saponin is higher in the tail portion than the main root portion. The main root of ginseng may be divided into white and red ginseng and black ginseng according to the chromaticity after processing. The black ginseng prepared according to the present invention will be named black ginseng because it has black color. Black ginseng according to the present invention first steamed red ginseng at 60-70 ° C. for 3-6 hours in a cauldron steamer, and then dried at a temperature of 70-75 ° C. until the water content reaches 28%. The black ginseng is repeatedly produced four times in the same manner as in the first step. The black ginseng, which has completed the first step five times, is steamed at a high pressure steamer at a temperature of 135 ° C. for about 3 to 6 hours, and dried to 25% moisture at 60 to 70 ° C. in an ganbanite hot air rotary dryer. Do this. In addition, the black ginsam produced in the above process is repeatedly produced four times in the same manner as in the second process. The black ginseng prepared by the above process is repeatedly steamed and dried, and the prepared black ginseng is dried with a final moisture content of 14% in a bulk dryer, and then foreign matters are removed to prepare black ginseng.

Example 1

In a solvent mixed with water and ethanol in the same weight ratio of 1: 1, 20 g of Astragalus, 20 g of Samsam, 20 g of Ogapi, 17 g of Bokyeong-dong, 16 g of Bokryeong, and 7 g of health were first steamed at 60 ° C. for 3 hours and then heated to 135 ° C. High pressure steaming and heat concentration for about 3 hours to prepare a 5 Brix concentrate. 100 g of red ginseng was soaked in the concentrate and infiltrated overnight, followed by primary steaming at a temperature of 60 ° C. for 3 hours in a cauldron steamer, and then dried until the amount of water reached 28% in an ocher drying chamber at 70 ° C. The process steps were repeated four more times and steamed at high pressure for about 3 hours at a temperature of 135 ° C. in a high pressure steamer, and dried at a temperature of 60 ° C. at a temperature of 60 ° C. in a ganbanite hot air rotary dryer. The process was repeated four more times and dried to a final moisture content of 14% in a bulk dryer to prepare 90 g of black ginseng.

Experimental Example 1

Black ginseng prepared by the method of the present invention was commissioned by the ginseng industry research institute of Chung-Ang University to analyze the content of saponin.

◈ Experiment Method

  1. Guobi

     100 g (powdered) of the sample was 95% EtOH for 2 hours after heat extraction and concentrated and analyzed by HPLC after pretreatment by the black ginseng component method of the food method. The test results are shown in Table 1.

  2. Guobi + 3rd Note

     Sample 100g (powdered), 95% EtOH 2 hours after the heat extraction for 2 hours, concentrated and analyzed by HPLC after pretreatment by the black ginseng component method of the food method. The test results are shown in Table 2.

  3. 4 times

     Sample 100g (powdered), 95% EtOH 2 hours after the heat extraction for 2 hours, concentrated and analyzed by HPLC after pretreatment by the black ginseng component method of the food method. The test results are shown in Table 3.

◈ HPLC analysis condition

  1. Mobile Phase

    Solvent A-ACN: Water: IPA = 80: 5: 15

    Solvent B-ACN: Water: IPA = 67: 21: 12

  2. Gradient

Time 0 28 35 45 50 51 57 58 65 % B 10 85 80 75 90 100 25 10 10

  3.Flow rate: 0.8 ㎎ / ㎖

  4. Detector: ELSD 2000ES

  5.Column: Prevail Carbohydrate ES column

Table 1.

Test Items Test result Remarks Irradiated Phonin (w / w%) 6.051 Food Code Processing Ginsenoside-Rh ₂ (w / w%) 0.167 HPLC analysis Ginsenoside-Rh ₁ (w / w%) 0.096 HPLC analysis Ginsenoside-Rg ₂ (w / w%) 0.015 HPLC analysis Ginsenoside-Rg ₃ (w / w%) 0.181 HPLC analysis Ginsenoside-Rg ₁ (w / w%) 0.136 HPLC analysis Ginsenoside-Rf (w / w%) 0.030 HPLC analysis Ginsenoside-Re (w / w%) 0 HPLC analysis Ginsenoside-Rd (w / w%) 0.009 HPLC analysis Ginsenoside-Rc + Rb ₂ (w / w%) 0.008 HPLC analysis Ginsenoside-Rb ₁ (w / w%) 0.045 HPLC analysis

Table 2.

Test Items Test result Remarks Irradiated Phonin (w / w%) 4.736 Food Code Processing Ginsenoside-Rh ₂ (w / w%) 0.115 HPLC analysis Ginsenoside-Rh ₁ (w / w%) 0.058 HPLC analysis Ginsenoside-Rg ₂ (w / w%) 0.009 HPLC analysis Ginsenoside-Rg ₃ (w / w%) 0.109 HPLC analysis Ginsenoside-Rg ₁ (w / w%) 0.024 HPLC analysis Ginsenoside-Rf (w / w%) 0.019 HPLC analysis Ginsenoside-Re (w / w%) 0 HPLC analysis Ginsenoside-Rd (w / w%) 0.006 HPLC analysis Ginsenoside-Rc + Rb ₂ (w / w%) 0.003 HPLC analysis Ginsenoside-Rb ₁ (w / w%) 0.022 HPLC analysis

Table 3.

Test Items Test result Remarks Irradiated Phonin (w / w%) 4.347 Food Code Processing Ginsenoside-Rh ₂ (w / w%) 0.102 HPLC analysis Ginsenoside-Rh ₁ (w / w%) 0.107 HPLC analysis Ginsenoside-Rg ₂ (w / w%) 0.042 HPLC analysis Ginsenoside-Rg ₃ (w / w%) 0.349 HPLC analysis Ginsenoside-Rg ₁ (w / w%) 0.011 HPLC analysis Ginsenoside-Rf (w / w%) 0.047 HPLC analysis Ginsenoside-Re (w / w%) 0.005 HPLC analysis Ginsenoside-Rd (w / w%) 0.024 HPLC analysis Ginsenoside-Rc + Rb ₂ (w / w%) 0.020 HPLC analysis Ginsenoside-Rb ₁ (w / w%) 0.102 HPLC analysis

Experimental Example 2

In order to confirm the effect of black ginseng prepared by the method of the present invention, the four-year-old ginseng cultivated together in the same region of Geumsan, Chungcheongnam-do was collected at the same time, and used as raw ginseng. Table 4 below shows the results of comparing the saponin components of the black ginseng and red ginseng root according to the present invention prepared by the manufacturing method as described above.

Table 4. Composition of Black Ginseng and Red Ginseng Root

Test Items Test result Remarks Black Ginseng Red ginseng root moisture(%) 15.82 13.88 n-BuOH Extract (mg / g) 42.78 22.10 Ginsenosides-Rg ₃ (mg / g) 1.24 0.18 Ginsenosides-Rg ₂ (mg / g) 1.20 0.08 Ginsenosides-Rg ₁ (mg / g) 0.50 0.18 Ginsenosides-Rf (mg / g) 0.50 0.22 Ginsenosides-Re (mg / g) 0.92 0.40 Ginsenosides-Rd (mg / g) 1.02 0.26 Ginsenosides-Rc (mg / g) 1.19 0.25 -Rb ₂ (mg / g) 0.98 0.19 -Rb ₁ (mg / g) 1.91 0.69             -Rh (mg / g) Confirm Confirm

As shown in Table 4, the saponin content of the black ginseng prepared according to the present invention can be seen to be significantly higher in all components than the red ginseng root. Black ginseng prepared according to the present invention is almost eluted when the above components are suspended in water, the pharmacological effect is significantly higher than other products.

Looking at the pharmacological action of the black ginseng component of the present invention Ginsenosides-Rg ₃ inhibits cancer cell metastasis, inhibits platelet aggregation and antithrombotic action, experimental liver injury inhibitory action, vascular relaxation action, anti-cancer drug resistance, Ginsenosides-Rg ₂ inhibits platelet aggregation, antithrombin, gland activation, memory loss, smooth muscle cell proliferation inhibition, acylcholine induction, currycolamine secretion and intracellular calcium influx, Ginsenosides-Rg ₁ Enhancer, platelet aggregation inhibitory, antithrombin, glandular activation, memory and learning function, corticosteroid receptor activation, protein synthesis promotion, antifatigue, antistress, central excitability, vasodilation and endogenous fever Defense against harmful stimuli such as substances, improving stressful sexual behavior disorders, anti-nephritis and renal blood flow, promoting neuronal survival Ginsenosides-Rf inhibits pain, inhibits lipid peroxidation, alcohol-induced brain development, and promotes cholesterol metabolism, anti-inflammatory, hepatic cell proliferation and DNA synthesis, hepatic impairment protection, and corticosteroid secretion. Ginsenosides-Re acts as a defense against corticosteroids, corticosteroid secretion, bone marrow cell DNA, RNA, protein, lipid synthesis, analgesic activity, flat muscle cell proliferation inhibition, vasodilation, cholesterol metabolism Ginsenosides-Rd promotes adrenal cortical stimulating hormone, corticosteroid secretion, mesanchyme cell proliferation, Ginsenosides-Rc promotes analgesic and corticosteroid secretion Action, PGI ₂ production promotion, liver, serum cholesterol, RNA synthesis promotion, bone marrow cell DNA, RNA, protein and lipid synthesis promotion, mesenchyme cell proliferation Ginsenosides-Rb ₂ promotes glucose and fat metabolism, antidiabetic action, ACTHcAMP, epinephrine-induced lipolysis, nitrogen metabolism equilibrium, high cholesterol and anti-arteriosclerosis, DNA, RNA, adrenal cortex Stimulating hormone, stimulating corticosteroid secretion, stimulating protein, lipid synthesis, antagonism of cancer toxin hormone, inhibiting smooth muscle cell proliferation, inhibiting tumor blood and stlstod, improving stress appetite loss, promoting antioxidant active substance production, ATP supply activation of liver tissue, increased ATP content, analgesic action, Ginsenosides-Rb ₁ is central and anti-stable, central feeding, inhibitory action, analgesic, anticonvulsant, adrenal cortex stimulating hormone And corticosterone secretion, anti-anxiety, cholesterol biosynthesis, high cholesterol and triglycerides and free fatty acids, bone marrow cells DNA, RNA, Promote protein and lipid synthesis, Promote protein synthesis, Promote nerve cell survival, Promote acetylcholine release, Improve memory, Inhibit platelet aggregation, Inhibit lipid peroxidation, Vasodilation, Promote cholesterol metabolism, Anti-inflammatory Action, protect liver injury, induce carbon tetrachloride, inhibit liver protein phosphorylation and inhibit intracellular calcium accumulation, activate phagocytosis. Ginsenosides-Rh ₁ inhibits experimental liver injury, promotes tumor cell differentiation, inhibits platelet aggregation and uses Activation action, Ginsenosides-Rh ₂ has the effect of inhibiting cancer cell proliferation, promoting the induction of cancer cell regeneration, inhibiting cancer cell invasion, inhibiting tumor proliferation, anticancer activity.

As mentioned above, according to the method for producing black ginseng according to the present invention, 20% by weight of sulfuric acid, 20% by weight of Sasam ginseng, 20% by weight of Ogapi, 17% by weight of Macmundong, 16% by weight of Bokryeong, and 7% by weight of health are heated. After infiltrating red ginseng into the concentrated concentrate, steaming and drying can be repeated nine times or more to produce black ginseng containing more saponins, and the black ginseng thus prepared can contain a higher content of saponins than other red ginseng roots. Make sure On the other hand, while the above has been described with reference to the preferred embodiments of the present invention, those skilled in the art to which the present invention pertains without departing from the spirit and scope of the present invention described in the claims below It will be understood that modifications and changes can be made.

Claims (2)

20 to 20% by weight of sulfuric acid, 20% by weight of Sasam, 20% by weight of Ogapi, 17% by weight of McMoon-Dong, 16% by weight of Fuling, and 7% by weight of Health are added to at least one solvent selected from the group consisting of water, ethanol, methanol and isopropanol. First steaming at 70 ° C. for 3 to 6 hours, and then steaming at high pressure at 135 ° C. for 3 to 6 hours and heating to prepare a concentrated solution of 5 Brix; After soaking red ginseng in the concentrate for 1 night and steaming it first at 60-70 ° C. for 3-6 hours in a cauldron, it is dried until 70% water content reaches 28% in 70-75 ° C. ocher drying room. Two process steps to make; Three process steps of repeating the two process steps four times again; 4 process steps of steaming black ginseng, which has completed the three process steps, at high pressure steamer at 135 ° C. for 3 to 6 hours, and drying them to 25% moisture at 60 to 70 ° C. in an elvan hot air rotary dryer; Five process steps of repeating the above four steps four times: and six process steps of drying the black ginseng, which has completed the five process steps, to a final moisture content of 14% in a bulk dryer. Manufacturing method. Black ginseng, characterized in that prepared according to the method of claim 1.