KR20040111473A - 강력한 알파 2-아드레노셉터 길항제인 폴리사이클릭 화합물 - Google Patents

강력한 알파 2-아드레노셉터 길항제인 폴리사이클릭 화합물 Download PDF

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Publication number
KR20040111473A
KR20040111473A KR10-2004-7015702A KR20047015702A KR20040111473A KR 20040111473 A KR20040111473 A KR 20040111473A KR 20047015702 A KR20047015702 A KR 20047015702A KR 20040111473 A KR20040111473 A KR 20040111473A
Authority
KR
South Korea
Prior art keywords
alkyl
alkoxy
octahydro
hydroxy
methyl
Prior art date
Application number
KR10-2004-7015702A
Other languages
English (en)
Korean (ko)
Inventor
다비드 딘벨레
레이자 조케라
아르토 톨바넨
안티 하아파린나
아르토 카르자라이넨
주카 살리넨
자리 라티라이넨
Original Assignee
오리온 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 오리온 코포레이션 filed Critical 오리온 코포레이션
Priority claimed from PCT/FI2003/000255 external-priority patent/WO2003082866A1/en
Publication of KR20040111473A publication Critical patent/KR20040111473A/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR10-2004-7015702A 2002-04-03 2003-04-03 강력한 알파 2-아드레노셉터 길항제인 폴리사이클릭 화합물 KR20040111473A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US36934702P 2002-04-03 2002-04-03
FI20020642A FI20020642A0 (fi) 2002-04-03 2002-04-03 Polysykliset yhdisteet tehokkaina alfa2-adrenoseptoriantagonisteina
US60/369,347 2002-04-03
FI20020642 2002-04-03
PCT/FI2003/000255 WO2003082866A1 (en) 2002-04-03 2003-04-03 Polycyclic compounds as potent alpha2-adrenoceptor antagonists

Publications (1)

Publication Number Publication Date
KR20040111473A true KR20040111473A (ko) 2004-12-31

Family

ID=8563695

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2004-7015702A KR20040111473A (ko) 2002-04-03 2003-04-03 강력한 알파 2-아드레노셉터 길항제인 폴리사이클릭 화합물

Country Status (6)

Country Link
KR (1) KR20040111473A (uk)
FI (1) FI20020642A0 (uk)
NO (1) NO20044627L (uk)
TW (1) TW200400028A (uk)
UA (1) UA80968C2 (uk)
ZA (1) ZA200407913B (uk)

Also Published As

Publication number Publication date
NO20044627L (no) 2004-10-27
UA80968C2 (en) 2007-11-26
TW200400028A (en) 2004-01-01
ZA200407913B (en) 2005-10-06
FI20020642A0 (fi) 2002-04-03

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Legal Events

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E601 Decision to refuse application
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AMND Amendment
B601 Maintenance of original decision after re-examination before a trial
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J301 Trial decision

Free format text: TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20101104

Effective date: 20110609