KR20040089096A - 렌티바이러스 벡터를 이용한 유전자 변형된 동물을제조하기 위한 방법 및 조성물 - Google Patents
렌티바이러스 벡터를 이용한 유전자 변형된 동물을제조하기 위한 방법 및 조성물 Download PDFInfo
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- KR20040089096A KR20040089096A KR10-2004-7009817A KR20047009817A KR20040089096A KR 20040089096 A KR20040089096 A KR 20040089096A KR 20047009817 A KR20047009817 A KR 20047009817A KR 20040089096 A KR20040089096 A KR 20040089096A
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Applications Claiming Priority (5)
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|---|---|---|---|
| US34484101P | 2001-12-21 | 2001-12-21 | |
| US60/344,841 | 2001-12-21 | ||
| US39847602P | 2002-07-25 | 2002-07-25 | |
| US60/398,476 | 2002-07-25 | ||
| PCT/US2002/041020 WO2003059923A2 (en) | 2001-12-21 | 2002-12-19 | Methods and compositions for generating a genetically modified animal using lentiviral vectors |
Publications (1)
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| KR20040089096A true KR20040089096A (ko) | 2004-10-20 |
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| KR10-2004-7009817A Withdrawn KR20040089096A (ko) | 2001-12-21 | 2002-12-19 | 렌티바이러스 벡터를 이용한 유전자 변형된 동물을제조하기 위한 방법 및 조성물 |
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Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103397019A (zh) | 2003-11-21 | 2013-11-20 | 雷维维科公司 | 干扰rna在生产转基因动物中的用途 |
| WO2005111204A2 (en) | 2004-05-07 | 2005-11-24 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Porcine forssman synthetase cdna and polypeptide |
| CA2597928A1 (en) * | 2005-02-16 | 2006-08-24 | Lentigen Corporation | Lentiviral vectors and their use |
| CA2617930A1 (en) | 2005-08-09 | 2007-03-29 | Revivicor, Inc. | Transgenic ungulates expressing ctla4-ig and uses thereof |
| GB0702694D0 (en) * | 2007-02-12 | 2007-03-21 | Ark Therapeutics Ltd | Vectors |
| JP5374389B2 (ja) * | 2008-01-29 | 2013-12-25 | 公益財団法人実験動物中央研究所 | 霊長類動物の初期胚への外来遺伝子導入法及び該導入法を含むトランスジェニック霊長類動物を作出する方法 |
| CN101717788B (zh) * | 2009-11-10 | 2012-06-20 | 中国农业大学 | 慢病毒感染胚胎的方法 |
| NZ759163A (en) | 2011-02-14 | 2023-03-31 | Revivicor Inc | Genetically modified pigs for xenotransplantation of vascularized xenografts and derivatives thereof |
| WO2017214937A1 (zh) * | 2016-06-16 | 2017-12-21 | 毛侃琅 | 一种促进 app 基因表达的慢病毒表达载体及其应用 |
| AU2018225180B2 (en) | 2017-02-22 | 2024-09-12 | Io Biosciences, Inc. | Nucleic acid constructs comprising gene editing multi-sites and uses thereof |
| US10828330B2 (en) | 2017-02-22 | 2020-11-10 | IO Bioscience, Inc. | Nucleic acid constructs comprising gene editing multi-sites and uses thereof |
| WO2022109316A1 (en) | 2020-11-20 | 2022-05-27 | Revivicor, Inc. | Multi-transgenic pigs with growth hormone receptor knockout for xenotransplantation |
| EP4404740A1 (en) | 2021-09-20 | 2024-07-31 | Revivicor Inc. | Multitransgenic pigs comprising ten genetic modifications for xenotransplantation |
| WO2025158071A1 (en) * | 2024-01-26 | 2025-07-31 | Sartorius Albumedix Limited | Retroviral preparations containing albumin for enhancing transduction efficiency, uses thereof for cell transduction |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5633076A (en) * | 1989-12-01 | 1997-05-27 | Pharming Bv | Method of producing a transgenic bovine or transgenic bovine embryo |
| DE69637677D1 (de) * | 1995-04-14 | 2008-10-23 | Univ Alabama Res Found | Transfer system basierend auf einem fusionsprotein und seine anwendungen. |
| US6271436B1 (en) * | 1996-10-11 | 2001-08-07 | The Texas A & M University System | Cells and methods for the generation of transgenic pigs |
| US6080912A (en) * | 1997-03-20 | 2000-06-27 | Wisconsin Alumni Research Foundation | Methods for creating transgenic animals |
| US6207455B1 (en) * | 1997-05-01 | 2001-03-27 | Lung-Ji Chang | Lentiviral vectors |
| DE69840671D1 (de) * | 1997-11-14 | 2009-04-30 | Cedars Sinai Medical Center | Transfektion und transfer nicht humaner männlicher keimzellen zur generierung transgener nicht humaner säugetiere |
| US6555342B1 (en) * | 1998-06-03 | 2003-04-29 | Uab Research Foundation | Fusion protein delivery system and uses thereof |
| US6313373B1 (en) * | 1998-10-30 | 2001-11-06 | Case Western Reserve University | Tissue specific promoters and transgenic mouse for the screening of pharmaceuticals |
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- 2002-12-19 KR KR10-2004-7009817A patent/KR20040089096A/ko not_active Withdrawn
- 2002-12-19 WO PCT/US2002/041020 patent/WO2003059923A2/en not_active Ceased
- 2002-12-19 CN CNA028282469A patent/CN1633495A/zh active Pending
- 2002-12-19 US US10/325,459 patent/US20030167500A1/en not_active Abandoned
- 2002-12-19 AU AU2002367024A patent/AU2002367024A1/en not_active Abandoned
- 2002-12-19 EP EP02806493A patent/EP1465981A4/en not_active Withdrawn
- 2002-12-19 JP JP2003560026A patent/JP2005538685A/ja active Pending
- 2002-12-19 CA CA002470527A patent/CA2470527A1/en not_active Abandoned
Also Published As
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|---|---|
| JP2005538685A (ja) | 2005-12-22 |
| EP1465981A2 (en) | 2004-10-13 |
| EP1465981A4 (en) | 2006-04-12 |
| AU2002367024A1 (en) | 2003-07-30 |
| WO2003059923A2 (en) | 2003-07-24 |
| US20030167500A1 (en) | 2003-09-04 |
| CA2470527A1 (en) | 2003-07-24 |
| WO2003059923A3 (en) | 2003-10-30 |
| CN1633495A (zh) | 2005-06-29 |
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