AU2002367024A1 - Methods and compositions for generating a genetically modified animal using lentiviral vectors - Google Patents
Methods and compositions for generating a genetically modified animal using lentiviral vectors Download PDFInfo
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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| PCT/US2002/041020 WO2003059923A2 (en) | 2001-12-21 | 2002-12-19 | Methods and compositions for generating a genetically modified animal using lentiviral vectors |
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| AU2004316293A1 (en) | 2003-11-21 | 2005-09-09 | Revivicor, Inc. | Use of interfering RNA in the production of transgenic animals |
| AU2005243169A1 (en) | 2004-05-07 | 2005-11-24 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Porcine Forssman synthetase protein, cDNA, genomic organization, and regulatory region |
| EP1858332A4 (en) * | 2005-02-16 | 2011-06-22 | Lentigen Corp | LENTIVIRUS VECTORS AND ITS USE |
| CA2617930A1 (en) | 2005-08-09 | 2007-03-29 | Revivicor, Inc. | Transgenic ungulates expressing ctla4-ig and uses thereof |
| GB0702694D0 (en) * | 2007-02-12 | 2007-03-21 | Ark Therapeutics Ltd | Vectors |
| WO2009096101A1 (ja) * | 2008-01-29 | 2009-08-06 | Central Institute For Experimental Animals | 霊長類動物の初期胚への外来遺伝子導入法及び該導入法を含むトランスジェニック霊長類動物を作出する方法 |
| CN101717788B (zh) * | 2009-11-10 | 2012-06-20 | 中国农业大学 | 慢病毒感染胚胎的方法 |
| NZ759163A (en) | 2011-02-14 | 2023-03-31 | Revivicor Inc | Genetically modified pigs for xenotransplantation of vascularized xenografts and derivatives thereof |
| WO2017214937A1 (zh) * | 2016-06-16 | 2017-12-21 | 毛侃琅 | 一种促进 app 基因表达的慢病毒表达载体及其应用 |
| CA3054307A1 (en) | 2017-02-22 | 2018-08-30 | Io Biosciences, Inc. | Nucleic acid constructs comprising gene editing multi-sites and uses thereof |
| US10828330B2 (en) | 2017-02-22 | 2020-11-10 | IO Bioscience, Inc. | Nucleic acid constructs comprising gene editing multi-sites and uses thereof |
| KR20230107335A (ko) | 2020-11-20 | 2023-07-14 | 레비비코르 인코포레이션 | 이종이식을 위한 성장 호르몬 수용체 녹아웃을 갖는 다중-전이유전자 돼지 |
| JP2024534702A (ja) | 2021-09-20 | 2024-09-20 | レバイビコア，インコーポレイティド | 異種移植のための１０個の遺伝子改変を含むマルチトランスジェニックブタ |
| WO2025158071A1 (en) * | 2024-01-26 | 2025-07-31 | Sartorius Albumedix Limited | Retroviral preparations containing albumin for enhancing transduction efficiency, uses thereof for cell transduction |
Family Cites Families (8)
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|---|---|---|---|---|
| US5633076A (en) * | 1989-12-01 | 1997-05-27 | Pharming Bv | Method of producing a transgenic bovine or transgenic bovine embryo |
| EP0873415B1 (en) * | 1995-04-14 | 2008-09-10 | University Of Alabama Research Foundation | Fusion protein delivery system and uses thereof |
| EP0941310A1 (en) * | 1996-10-11 | 1999-09-15 | THE TEXAS A&M UNIVERSITY SYSTEM | Methods for the generation of primordial germ cells and transgenic animal species |
| US6080912A (en) * | 1997-03-20 | 2000-06-27 | Wisconsin Alumni Research Foundation | Methods for creating transgenic animals |
| US6207455B1 (en) * | 1997-05-01 | 2001-03-27 | Lung-Ji Chang | Lentiviral vectors |
| EP1030929B1 (en) * | 1997-11-14 | 2009-03-18 | Cedars-Sinai Medical Center | Transfection and transfer of non-human male germ cells for generation of transgenic non-human mammals |
| US6555342B1 (en) * | 1998-06-03 | 2003-04-29 | Uab Research Foundation | Fusion protein delivery system and uses thereof |
| WO2000026343A2 (en) * | 1998-10-30 | 2000-05-11 | Case Western Reserve University | Tissue specific promoters and transgenic animals for the screening of pharmaceuticals |
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- 2002-12-19 AU AU2002367024A patent/AU2002367024A1/en not_active Abandoned
- 2002-12-19 CA CA002470527A patent/CA2470527A1/en not_active Abandoned
- 2002-12-19 WO PCT/US2002/041020 patent/WO2003059923A2/en not_active Ceased
- 2002-12-19 KR KR10-2004-7009817A patent/KR20040089096A/ko not_active Withdrawn
- 2002-12-19 CN CNA028282469A patent/CN1633495A/zh active Pending
- 2002-12-19 EP EP02806493A patent/EP1465981A4/en not_active Withdrawn
- 2002-12-19 JP JP2003560026A patent/JP2005538685A/ja active Pending
- 2002-12-19 US US10/325,459 patent/US20030167500A1/en not_active Abandoned
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| EP1465981A2 (en) | 2004-10-13 |
| KR20040089096A (ko) | 2004-10-20 |
| CA2470527A1 (en) | 2003-07-24 |
| EP1465981A4 (en) | 2006-04-12 |
| CN1633495A (zh) | 2005-06-29 |
| WO2003059923A2 (en) | 2003-07-24 |
| WO2003059923A3 (en) | 2003-10-30 |
| US20030167500A1 (en) | 2003-09-04 |
| JP2005538685A (ja) | 2005-12-22 |
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