KR20040068544A - 아테롬성 동맥경화증의 예후 표지로서의 가용성 cd40l(cd154) - Google Patents
아테롬성 동맥경화증의 예후 표지로서의 가용성 cd40l(cd154) Download PDFInfo
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- KR20040068544A KR20040068544A KR10-2004-7006789A KR20047006789A KR20040068544A KR 20040068544 A KR20040068544 A KR 20040068544A KR 20047006789 A KR20047006789 A KR 20047006789A KR 20040068544 A KR20040068544 A KR 20040068544A
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Classifications
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
- G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/323—Arteriosclerosis, Stenosis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
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- Diabetes (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
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| US33884101P | 2001-11-05 | 2001-11-05 | |
| US60/338,841 | 2001-11-05 | ||
| PCT/US2002/035505 WO2003040691A2 (en) | 2001-11-05 | 2002-11-05 | Soluble cd40l(cd154) as a prognostic marker of atherosclerotic diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20040068544A true KR20040068544A (ko) | 2004-07-31 |
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| Application Number | Title | Priority Date | Filing Date |
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| Country | Link |
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| US (2) | US7189518B2 (https=) |
| EP (1) | EP1451577A4 (https=) |
| JP (1) | JP2005515407A (https=) |
| KR (1) | KR20040068544A (https=) |
| CN (1) | CN1613012A (https=) |
| CA (1) | CA2464531A1 (https=) |
| WO (1) | WO2003040691A2 (https=) |
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| US6727102B1 (en) * | 1997-06-20 | 2004-04-27 | Leuven Research & Development Vzw | Assays, antibodies, and standards for detection of oxidized and MDA-modified low density lipoproteins |
| US6309888B1 (en) * | 1998-09-04 | 2001-10-30 | Leuven Research & Development Vzw | Detection and determination of the stages of coronary artery disease |
| WO2002012266A1 (en) | 2000-08-05 | 2002-02-14 | Glaxo Group Limited | 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents |
| US6858596B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivative |
| US6858593B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
| GB0019172D0 (en) | 2000-08-05 | 2000-09-27 | Glaxo Group Ltd | Novel compounds |
| US6777399B2 (en) | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
| WO2002018324A2 (en) | 2000-08-29 | 2002-03-07 | Nobex Corporation | Immunoregulatory compounds, derivatives thereof and their use |
| UA77656C2 (en) | 2001-04-07 | 2007-01-15 | Glaxo Group Ltd | S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent |
| PT1383786E (pt) | 2001-04-30 | 2008-12-30 | Glaxo Group Ltd | Derivados anti-inflamatórios de éster 17.beta-carbotioato de androstano com um grupo éster ciclíco na posição 17.alfa |
| US7642286B2 (en) * | 2001-06-21 | 2010-01-05 | Andrx Pharmaceuticals, Inc. | Stable pharmaceutical compositions containing pravastatin |
| US8048924B2 (en) * | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
| JP2005515407A (ja) * | 2001-11-05 | 2005-05-26 | ザ ブライアム アンド ウィミンズ ホスピタル インコーポレーテッド | アテローム硬化症の予後マーカーとしての可溶性cd40l(cd154) |
| GB2389530B (en) | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
| ATE394679T1 (de) * | 2002-11-16 | 2008-05-15 | Dade Behring Marburg Gmbh | Scd40l, papp-a und plazentaler-wachstumsfaktor (pigf) als biochemische markerkombinationen bei kardiovaskulären erkrankungen |
| EP1530047A1 (en) * | 2003-11-07 | 2005-05-11 | Roche Diagnostics GmbH | Proximal markers of arterial thrombosis and inflammation for risk stratification of coronary heart disease |
| US20050181451A1 (en) * | 2004-02-12 | 2005-08-18 | Bates Harold M. | Detection of asymptomatic coronary artery disease using atherogenic proteins and acute phase reactants |
| WO2005087266A1 (en) * | 2004-03-05 | 2005-09-22 | Vddi Pharmaceuticals | Combination therapy for inhibition of platelet aggregation |
| WO2005110422A2 (en) * | 2004-05-19 | 2005-11-24 | Boehringer Ingelheim International Gmbh | Treatment of diseases associated with altered level of amyloid beta peptides |
| DE102004028303A1 (de) | 2004-06-11 | 2005-12-29 | Roche Diagnostics Gmbh | Verfahren und Vorrichtung zum Nachweis von Analyten |
| EP1615035B1 (en) * | 2004-07-07 | 2007-06-06 | F.Hoffmann-La Roche Ag | Multimarker panel for diabetes type 1 and 2 |
| DK1773767T3 (en) | 2004-07-07 | 2016-03-21 | Biocon Ltd | Synthesis of azo bound in immune regulatory relations |
| US7560227B2 (en) * | 2005-02-28 | 2009-07-14 | University Of Massachusetts | Biomarkers of vulnerable atherosclerotic plaques and methods of use |
| WO2007042778A2 (en) * | 2005-10-11 | 2007-04-19 | St George's Enterprises Limited | Monitoring cardiovascular disease by determining the expression of kir2ds2 and/or dap12 |
| EP2431746A1 (en) | 2005-11-17 | 2012-03-21 | Biogen Idec MA Inc. | Platelet aggregation assays |
| EP2302395B1 (en) | 2006-06-07 | 2015-04-15 | Health Diagnostic Laboratory, Inc. | Markers associated with arteriovascular events and methods of use thereof |
| US20120034629A1 (en) * | 2007-08-17 | 2012-02-09 | Siemens Healthcare Diagnostics Inc. | Prediction of non-fatal and fatal atherothrombotic events |
| US9359633B2 (en) * | 2007-11-05 | 2016-06-07 | Nordic Bioscience A/S | Biochemical markers for CVD risk assessment |
| AU2010324544A1 (en) | 2009-11-27 | 2012-06-21 | Baker Idi Heart And Diabetes Institute Holdings Limited | Lipid biomarkers for stable and unstable heart disease |
| US20190263888A1 (en) | 2010-10-19 | 2019-08-29 | Op-T Llc | Therapeutic peptides and methods for treating autoimmune related disease |
| JP5857312B2 (ja) * | 2011-08-11 | 2016-02-10 | 積水メディカル株式会社 | 心疾患診断マーカー |
| CN103163295B (zh) * | 2011-12-08 | 2015-11-18 | 吴宗贵 | 一种用于急性冠脉综合征的液相芯片试剂盒以其制备方法 |
| MX382403B (es) * | 2012-08-16 | 2025-03-13 | Critical Care Diagnostics Inc | Métodos para predecir el riesgo de desarrollar hipertensión. |
| EP2968292A4 (en) * | 2013-03-15 | 2016-11-23 | Intermune Inc | METHOD FOR IMPROVING MICROVASCULAR INTEGRITY |
| ES3031007T3 (en) * | 2017-11-10 | 2025-07-03 | Op T Llc | Peptide for preventing, modulating and/or reducing cardiovascular disease |
| US11793854B2 (en) | 2019-03-21 | 2023-10-24 | Op-T Llc | Methods for reducing symptoms of multiple sclerosis using a six-amino acid long peptide that inhibits CD40-CD150 interaction |
| US12048734B2 (en) | 2020-04-17 | 2024-07-30 | Op-T Llc | Bioactive peptides and methods of use thereof |
| JP7584125B2 (ja) | 2020-11-02 | 2024-11-15 | 国立大学法人千葉大学 | 心血管イベントの発症リスクの検査方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5358844A (en) * | 1993-02-18 | 1994-10-25 | Brigham And Women's Hospital, Inc. | Preservation of blood platelets |
| US5622867A (en) * | 1994-10-19 | 1997-04-22 | Lifecell Corporation | Prolonged preservation of blood platelets |
| US5919614A (en) * | 1994-10-19 | 1999-07-06 | Lifecell Corporation | Composition comprising three platelet lesion inhibitors for platelet storage |
| WO1998020155A1 (en) * | 1996-11-08 | 1998-05-14 | New York Society For The Relief Of The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Diagnostic methods using cd40 ligand assay |
| ATE530180T1 (de) | 1997-04-02 | 2011-11-15 | Brigham & Womens Hospital | Verfahren zur ermittlung der individualen risikoprofile atherosklerotischen erkrankungen |
| US6117911A (en) * | 1997-04-11 | 2000-09-12 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
| AU782386C (en) | 1999-08-31 | 2006-08-10 | Brigham And Women's Hospital | Systemic inflammatory markers as diagnostic tools in the prevention of atherosclerotic diseases |
| JP2001322933A (ja) | 2000-05-15 | 2001-11-20 | Ucb Sa | Cd40シグナル遮断剤 |
| JP2005515407A (ja) * | 2001-11-05 | 2005-05-26 | ザ ブライアム アンド ウィミンズ ホスピタル インコーポレーテッド | アテローム硬化症の予後マーカーとしての可溶性cd40l(cd154) |
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2002
- 2002-11-05 JP JP2003542897A patent/JP2005515407A/ja active Pending
- 2002-11-05 EP EP02780578A patent/EP1451577A4/en not_active Ceased
- 2002-11-05 CN CNA028267117A patent/CN1613012A/zh active Pending
- 2002-11-05 WO PCT/US2002/035505 patent/WO2003040691A2/en not_active Ceased
- 2002-11-05 US US10/288,253 patent/US7189518B2/en not_active Expired - Fee Related
- 2002-11-05 CA CA002464531A patent/CA2464531A1/en not_active Abandoned
- 2002-11-05 KR KR10-2004-7006789A patent/KR20040068544A/ko not_active Withdrawn
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2007
- 2007-03-12 US US11/716,996 patent/US20080058360A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7189518B2 (en) | 2007-03-13 |
| WO2003040691A3 (en) | 2003-11-13 |
| EP1451577A4 (en) | 2006-03-15 |
| US20080058360A1 (en) | 2008-03-06 |
| US20030152566A1 (en) | 2003-08-14 |
| WO2003040691A2 (en) | 2003-05-15 |
| CN1613012A (zh) | 2005-05-04 |
| CA2464531A1 (en) | 2003-05-15 |
| JP2005515407A (ja) | 2005-05-26 |
| EP1451577A2 (en) | 2004-09-01 |
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| PA0105 | International application |
Patent event date: 20040504 Patent event code: PA01051R01D Comment text: International Patent Application |
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| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |