KR20040005407A - Anti-aging composition - Google Patents

Abstract

PURPOSE: Provided is an antiaging composition which induces and facilitates the secretion of various kinds of hormones to exert the antiaging effect, and inhibits aging caused by free radicals to effectively reinforce the antioxidation reaction. CONSTITUTION: An anti-aging composition comprises 1-35wt.% of an antioxidant, 5-60wt.% of amino acids, 0.01-10wt.% of vitamins, 0.5-16wt.% of minerals, and 5-40wt.% of medicinal herbs. The antioxidant is selected from the group consisting of catechin, flavonoid, carotenoid, glutathione, grape seed extract, green tea extract, soybean extract, unpolished rice germ extract, and mixtures thereof.

Description

Anti-aging composition {ANTI-AGING COMPOSITION}

The present invention relates to an anti-aging composition comprising an antioxidant, amino acids, herbal medicines, vitamins and minerals, wherein the anti-aging action is effectively increased.

Recently, the cause of aging is aging caused by cell destruction and gene damage caused by free radicals. One of the most obvious changes in the body during the aging process is hormonal deficiency. Therefore, by protecting the cells by supplementing antioxidants to prevent aging, by treating and / or preventing various symptoms caused by hormone deficiency, aging can be effectively suppressed. Hormones related to aging include growth hormone (HGH), DHEA hormone, testosterone, estrogen, melatonin, and thyroid hormones. These hormones are reduced to below normal levels after age 30. Aging symptoms are mostly lethargic and unstable. Sexual function is reduced, wrinkles are formed, fat in the body is increased, and various elderly diseases, namely heart disease, hypertension, diabetes, osteoporosis, stroke, dementia, cataract, decreased vision, tinnitus, and the like. For example, in men, postmenopausal estrogens are markedly reduced and various aging phenomena occur.Replenishing estrogens can alleviate the deterioration of skin function, osteoporosis, arteriosclerosis, growth hormones increase muscle tone, thicken flesh, and bone density. There is a characteristic that makes it higher. On the other hand, free radicals are generated due to breathing, food, pollution, stress, drug metabolism, and electromagnetic waves, attacking or modifying cells, genes, and proteins in the body, resulting in cancer, dementia, and chronic diseases. This is free radicals, and it also acts as a factor in aging. Thus, antioxidant activity prevents many phenomena occurring at the cellular level, thereby protecting the cells and inhibiting aging. In addition, vitamins are nutrients contained in the body, which are essential for promoting growth and maintaining health, and minerals are nutrients that require relatively small amounts for growth, maintenance, and reproduction of the human body, forming acid-base equilibrium and tissues (connective tissue, etc.) in the body, It helps to control the balance of water inside and outside the cell, which helps to suppress aging.

An object of the present invention is to provide an antioxidant, amino acids, herbal medicines, vitamins and mineral-containing compositions which are useful for inducing and promoting hormone secretion and for inhibiting aging of body organs and skin by free radicals.

The present invention includes catechins (Catectin), flavonoids (Flavinoids), carotenoids (Carotenoids), yeast derived glutathione (glutathione), grape seed extract, picenol, green tea extract, soybean extract, brown rice germ extract-containing formulations and these 1-35% by weight antioxidant selected from the group consisting of; Ii) 5-60% by weight of amino acids selected from the group consisting of glycine, L-glutamine, L-lysine, arginine, tryptophan, tyrosine, carnitine, ornithine, peptides and combinations thereof; Iii) 0.01-10% by weight of vitamins selected from the group consisting of d-tocopherol, beta carotene, vitamin C, vitamin A, vitamin B group, folic acid, biotin, inositol, vitamin P and combinations thereof; And iii) 0.5-16% by weight minerals selected from the group consisting of calcium, phosphorus, magnesium, sodium, potassium, iron, iodine, zinc, copper, selenium, manganese, chromium, molybdenum and combinations thereof; vi) 5-40 selected from the group consisting of deer antler, ginseng, donkey, astragalus, succinate, ganoderma lucidum, ogapi, medicinal herb, brown root, bokbunja, cornus, wolfberry, royal jelly, pollen, red clova, pomegranate extract, and combinations thereof It provides an anti-aging composition, characterized in that it contains by weight of the herbal medicines.

Antioxidants, such as catechins, flavonoids, carotenoids, yeast-derived glutathiones, d-tocopherols, beta carotene, vitamin C, and vitamin A-containing agents, are at the cellular level Many phenomena occur in the body, such as oxidative stress. Antioxidants do not interfere with the overall antioxidant action, and prevent oxidation damage. Antioxidants can prevent the formation of free radicals that cause aging in the body.

Amino acids, such as ornithine, glycine, L-glutamine, L-lysine, arginine and tryptophan, tyrosine, protein hydrolysates, and herbal medicines such as deer antler, ginseng, Astragalus, spermatozoon, Angelica, medicinal herbs, roots, and scabies Aging can be suppressed by promoting secretion. For example, ornithine, arginine, lysine, glutamine, and glycine have a function of inducing growth hormone secretion in the body, and tryptophan stimulates the production of neurotransmitters serotonin and melatonin. Protein hydrolysates also promote growth hormone secretion and are used as a necessary substance in the synthesis of various hormones. Deer Antlers also have horn growth stimulants, which are closely related to testosterone changes, including testosterone, and the roots contain precursors of female hormones called estrogens.

Vitamins are nutrients contained in the body and are essential for promoting growth and maintaining health. In particular, vitamin B6 is involved in hormonal synthesis, vitamin B2 and niacin help protect and promote skin growth, and vitamin C is a connective tissue between cells. It enhances the absorption of iron and calcium, has the function of blood regeneration and capillary wall strengthening, promotes the development of teeth, bones, etc., and increases the resistance to bacteria. Vitamin E is used as an antioxidant and helps prevent aging, harden the arteries and prevent adult diseases, and improve the reproductive function of animals.

Minerals are nutrients that require relatively small amounts for growth, maintenance and reproduction of the human body. They help to balance acid-base equilibrium and formation of tissues (connective tissue, etc.) and balance water in and out of cells. For example, zinc assists in various metabolic and hormonal actions, while iodine is involved in thyroid hormone control. In addition, the lack of calcium in the blood parathyroid hormone (PHT) acts to dissolve the calcium accumulated in the bones to cause bone weakening and promote aging.

The anti-aging composition of the present invention may further comprise fragrances, sweeteners, food colorings, stabilizers and other preservatives. For example, the anti-aging composition adds 0.01-0.2 wt% sorbitol, 0.01-0.05 wt% benzoic acid, 0.01-0.05 wt% natural orange flavor, 0.01-0.05 wt% fructose and 0.01-0.05 wt% citric acid It can be included as. In addition, the anti-aging composition of the present invention may be in the form of tablets, powders, granules, capsules, pills, contents solution.

Example

The following examples are merely illustrative of the present invention and should not be construed as limiting the scope of the present invention. Those skilled in the art will understand that various modifications and variations are possible within the scope of the technical idea of the present invention.

Example 1: Preparation of Anti-Aging Composition

5 wt% glutathione yeast, 5 wt% green tea extract, 4 wt% selenium yeast, 3 wt% grape seed extract, 3 wt% pycnenol, 3 at a temperature of 18-25 and a pressure of 0.1-10 wt Wt% pollen, 3 wt% red clova, 3 wt% chlorella, 15 wt% arginine, 6 wt% L-glutamine, 6 wt% L-lysine, 5 wt% glycine, 5 wt% Carnitine, 3 wt% tyrosine, 2 wt% tryptophan, 5 wt% vitamin C, 1 wt% beta carotene, 1 wt% d-tocopherol, 1.5 wt% vitamin B3, 0.5 wt% vitamin B6, 0.5 wt% vitamin B1, 0.1 wt% folic acid, 5 wt% calcium, 5 wt% magnesium, 5 wt% potassium, 1 wt% iron, 1 wt% copper, 0.01 wt% iodine, 1.7 Weight percent zinc and 0.3 weight percent manganese were mixed evenly for 30 hours. The mixture is then filled into capsules.

Example 2: Preparation of Anti-Aging Composition

5% by weight antler, 5% by weight powder, 5% by weight of brown root, 5% by weight of ginseng, 4% by weight of ginseng, 4% by weight of Angelica, at a temperature of 18 to 25 and a pressure of 0.1 to 10 atmospheres, 15 weight percent arginine, 6 weight percent L-glutamine, 6 weight percent L-lysine, 5 weight percent glycine, 5 weight percent carnitine, 3 weight percent tyrosine, 2 weight percent tryptophan, 5 weight percent Vitamin C, 1 wt% beta carotene, 1 wt% d-tocopherol, 1.5 wt% vitamin B3, 0.5 wt% vitamin B6, 0.5 wt% vitamin B1, 0.1 wt% folic acid, 5 wt% calcium , 5 wt% magnesium, 5 wt% potassium, 1 wt% iron, 1 wt% copper 0.01 wt% iodine, 1.7 wt% zinc and 0.3 wt% manganese were mixed evenly for 30 hours. The reaction mixture was then filled into capsules.

Example 3 Growth Hormone Secretion Effect after Anti-Aging Composition

Blood anti-aging compositions prepared according to Examples 1 and 2 were taken after oral administration to 10 adult men and women (35 to 65 years) for 8 weeks to measure blood growth hormone (IGF-1) values. 1 is shown.

Measuring time Growth Hormone (ng / ml) Example 1 Example 2 south female south female first 98.9 +-(5.1) 96.5 +-(6.1) 98.9 +-(6.4) 96.5 +-(5.0) 1 week later 112.3 +-(5.5) 109.3 +-(7.2) 119.5 +-(6.5) 118.5 +-(8.7) after 2 weeks 123.8 +-(10.9) 126.8 +-(8.9) 135.8 +-(12.4) 145.8 +-(14.8) 3 weeks later 134.6 +-(8.8) 130.6 +-(6.4) 166.6 +-(10.3) 154.1 +-(7.4) 4 weeks later 159.5 +-(7.6) 149.5 +-(6.6) 189.7 +-(11.5) 169.5 +-(10.0) 8 weeks later 170.7 +-(8.7) 160.7 +-(10.4) 209.8 +-(7.4) 189.8 +-(7.5)

Example 4: Antioxidant Effect of Anti-Aging Compositions

5% of the anti-aging composition prepared in Examples 1 and 2 was mixed with feed and freely ingested in mice for 2 weeks and compared with administration of vitamin C. After 2 weeks, the organs of the brain and heart were extracted and peroxidated in each organ. Lipids and SOD were measured.

SOD activity brain Heart Control 100% 100% Vitamin c 115% 111% Example 1 125% 131% Example 2 122% 125% Peroxide (LPO) brain Heart Control 100% 100% Vitamin c 89% 92% Example 1 70% 73% Example 2 78% 75%

The anti-aging composition of the present invention induces and promotes the release of various hormones such as growth hormones to improve the aging symptoms, and effectively enhance the anti-aging action by inhibiting the aging of body organs and skin by free radicals. In particular, the anti-aging composition of the present invention may contain antioxidants, amino acids, herbal medicines, vitamins and minerals to prevent / improve adult diseases and senile diseases, and to prevent / treat brain function improvement and dwarfism in growing adolescents.

Claims (3)

Iii) Catectin, flavonoids, carotenoids, yeast-derived glutathione, grape seed extract, pixenol, green tea extract, soybean extract, brown rice germ extract-containing preparations and combinations thereof 1-35% by weight antioxidant selected from the group consisting of; Ii) 5-60% by weight of amino acids selected from the group consisting of glycine, L-glutamine, L-lysine, arginine, tryptophan, tyrosine, carnitine, ornithine, peptides and combinations thereof; Iii) 0.01-10% by weight of vitamins selected from the group consisting of d-tocopherol, beta carotene, vitamin C, vitamin A, vitamin B group, folic acid, biotin, inositol, vitamin P and combinations thereof; And Iii) 0.5-16% by weight minerals selected from the group consisting of calcium, phosphorus, magnesium, sodium, potassium, iron, iodine, zinc, copper, selenium, manganese, chromium, molybdenum and combinations thereof; vi) 5-40 selected from the group consisting of deer antler, ginseng, donkey, astragalus, succinate, ganoderma lucidum, ogapi, medicinal herb, brown root, bokbunja, cornus, wolfberry, royal jelly, pollen, red clova, pomegranate extract, and combinations thereof An anti-aging composition, characterized in that it contains by weight of the herbal medicines. The anti-aging composition according to claim 1, further comprising a fragrance, sweetener, food coloring, stabilizer and other preservatives. The anti-aging composition according to claim 1 or 2, which is in the form of tablets, powders, capsules, granules, pills, or liquid solutions.