KR20030081337A - Ｒｇｓ 단백질의 모듈레이터 검출용 방법 및 세포 - Google Patents

Ｒｇｓ 단백질의 모듈레이터 검출용 방법 및 세포 Download PDF

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Publication number
KR20030081337A
KR20030081337A KR10-2003-7007356A KR20037007356A KR20030081337A KR 20030081337 A KR20030081337 A KR 20030081337A KR 20037007356 A KR20037007356 A KR 20037007356A KR 20030081337 A KR20030081337 A KR 20030081337A
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KR
South Korea
Prior art keywords
terminus
rgs4
cell
rgs
rgs7
Prior art date
Application number
KR10-2003-7007356A
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English (en)
Korean (ko)
Inventor
영캐슬린에이치
카오지안
셰우이데이비드
Original Assignee
와이어쓰
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Application filed by 와이어쓰 filed Critical 와이어쓰
Publication of KR20030081337A publication Critical patent/KR20030081337A/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR10-2003-7007356A 2000-12-01 2001-12-03 Ｒｇｓ 단백질의 모듈레이터 검출용 방법 및 세포 KR20030081337A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25014700P 2000-12-01 2000-12-01
US60/250,147 2000-12-01
PCT/US2001/045105 WO2002050104A2 (en) 2000-12-01 2001-12-03 Methods and cells for detecting modulators of rgs proteins

Publications (1)

Publication Number Publication Date
KR20030081337A true KR20030081337A (ko) 2003-10-17

Family

ID=22946480

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2003-7007356A KR20030081337A (ko) 2000-12-01 2001-12-03 Ｒｇｓ 단백질의 모듈레이터 검출용 방법 및 세포

Country Status (9)

Country Link
EP (1) EP1339740A2 (zh)
JP (1) JP2004520824A (zh)
KR (1) KR20030081337A (zh)
CN (1) CN1478097A (zh)
AU (1) AU2002243255A1 (zh)
CA (1) CA2430475A1 (zh)
IL (1) IL156199A0 (zh)
MX (1) MXPA03004700A (zh)
WO (1) WO2002050104A2 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100968640B1 (ko) * 2007-10-06 2010-07-06 재단법인서울대학교산학협력재단 단일세포의 신호분석방법

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7846671B2 (en) 2002-01-28 2010-12-07 Bristol-Myers Squibb Company Methods of screening for agents that modulate the interaction of RGS and Gαq and urinary incontinence
US10364421B2 (en) * 2015-02-06 2019-07-30 Cargill, Incorporated Modified glucoamylase enzymes and yeast strains having enhanced bioproduct production
CN105126079B (zh) * 2015-09-29 2019-03-01 武汉大学 G蛋白信号转导调节蛋白14（rgs14）在治疗心肌肥厚中的功能及应用
CN105106936B (zh) * 2015-09-29 2018-05-15 武汉大学 G蛋白信号转导调节蛋白10（rgs10）在治疗心肌肥厚中的功能及应用
CA3032736A1 (en) 2016-08-05 2018-02-08 Cargill, Incorporated Leader-modified glucoamylase polypeptides and engineered yeast strains having enhanced bioproduct production

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU733007B2 (en) * 1996-09-24 2001-05-03 Cadus Pharmaceutical Corporation Methods and compositions for identifying receptor effectors
AU3977699A (en) * 1998-05-08 1999-11-29 Cadus Pharmaceutical Corporation Ags proteins and nucleic acid molecules and uses therefor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100968640B1 (ko) * 2007-10-06 2010-07-06 재단법인서울대학교산학협력재단 단일세포의 신호분석방법

Also Published As

Publication number Publication date
IL156199A0 (en) 2003-12-23
WO2002050104A9 (en) 2002-12-19
WO2002050104A3 (en) 2003-04-10
CA2430475A1 (en) 2002-06-27
CN1478097A (zh) 2004-02-25
WO2002050104A2 (en) 2002-06-27
AU2002243255A1 (en) 2002-07-01
JP2004520824A (ja) 2004-07-15
MXPA03004700A (es) 2003-08-19
EP1339740A2 (en) 2003-09-03

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