KR20030034071A - 항혈전제 - Google Patents
항혈전제 Download PDFInfo
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- KR20030034071A KR20030034071A KR1020027015403A KR20027015403A KR20030034071A KR 20030034071 A KR20030034071 A KR 20030034071A KR 1020027015403 A KR1020027015403 A KR 1020027015403A KR 20027015403 A KR20027015403 A KR 20027015403A KR 20030034071 A KR20030034071 A KR 20030034071A
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
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| JP4485806B2 (ja) | 2002-03-20 | 2010-06-23 | ユニヴァーシティ オブ メリーランド，ボルチモア | 神経系細胞の非選択的陽イオンチャネルおよび脳腫脹を治療する方法 |
| US8980952B2 (en) | 2002-03-20 | 2015-03-17 | University Of Maryland, Baltimore | Methods for treating brain swelling with a compound that blocks a non-selective cation channel |
| US7872048B2 (en) | 2004-09-18 | 2011-01-18 | University Of Maryland, Baltimore | Methods for treating spinal cord injury with a compound that inhibits a NCCa-ATP channel |
| US10583094B2 (en) * | 2004-09-18 | 2020-03-10 | University Of Maryland | Therapeutic methods that target the NCCA-ATP channel |
| CA2674949A1 (en) | 2007-01-12 | 2008-07-24 | J. Marc Simard | Targeting ncca-atp channel for organ protection following ischemic episode |
| CA2691199C (en) | 2007-06-22 | 2017-09-12 | Marc J. Simard | Inhibitors of ncca-atp channels for therapy |
| CA2700701C (en) | 2007-09-26 | 2020-12-29 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substitution in cdr |
| LT3002298T (lt) * | 2007-11-21 | 2019-12-10 | Univ Oregon Health & Science | Monokloniniai antikūnai prieš faktorių xi ir jų panaudojimo būdai |
| US9518128B2 (en) | 2011-12-14 | 2016-12-13 | Janssen Pharmaceuticals, Inc. | Thrombin-binding antibody molecules |
| GB201121513D0 (en) * | 2011-12-14 | 2012-01-25 | Cambridge Entpr Ltd | Thrombin-binding antibody molecules and uses thereof |
| CN118320078A (zh) * | 2016-12-23 | 2024-07-12 | 诺华股份有限公司 | 采用抗因子XI/XIa抗体治疗的方法 |
| US20240018503A1 (en) * | 2017-04-27 | 2024-01-18 | Chugai Seiyaku Kabushiki Kaisha | Coagulation factor ix with improved pharmacokinetics |
| EP3617316A4 (en) | 2017-04-27 | 2020-12-23 | Chugai Seiyaku Kabushiki Kaisha | COAGULATION FACTOR IX WITH IMPROVED PHARMACOKINETICS |
| CN115448985A (zh) * | 2021-06-08 | 2022-12-09 | 上海循曜生物科技有限公司 | 新型抗栓抗体 |
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| CA2049655C (en) * | 1990-09-17 | 1996-11-12 | Akio Odawara | Pharmaceutical composition for inhibiting platelet aggregation |
| MA24512A1 (fr) * | 1996-01-17 | 1998-12-31 | Univ Vermont And State Agrienl | Procede pour la preparation d'agents anticoagulants utiles dans le traitement de la thrombose |
| WO2000007626A1 (en) * | 1998-08-07 | 2000-02-17 | Smithkline Beecham Corporation | Use of anti-coagulation factor antibodies as long-lasting protective agents |
| DK1107996T3 (da) * | 1998-08-28 | 2002-09-16 | Genentech Inc | Humane anti-faktor IX/IXa-antistoffer |
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Also Published As
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| NZ522632A (en) | 2005-05-27 |
| WO2001087339A1 (en) | 2001-11-22 |
| HUP0301804A3 (en) | 2005-12-28 |
| EP1282444B1 (en) | 2006-11-22 |
| HUP0301804A2 (hu) | 2003-08-28 |
| DE60032029T2 (de) | 2007-05-31 |
| US20050037006A1 (en) | 2005-02-17 |
| EP1825864A2 (en) | 2007-08-29 |
| AU7858400A (en) | 2001-11-26 |
| BR0015872A (pt) | 2004-08-03 |
| NO20025463D0 (no) | 2002-11-14 |
| CN1501812A (zh) | 2004-06-02 |
| AU2000278584B2 (en) | 2006-11-16 |
| CN101134107A (zh) | 2008-03-05 |
| ES2277597T3 (es) | 2007-07-16 |
| EP1282444A1 (en) | 2003-02-12 |
| ZA200209265B (en) | 2003-10-22 |
| EP1282444A4 (en) | 2004-06-30 |
| MXPA02011385A (es) | 2004-01-26 |
| PL360060A1 (en) | 2004-09-06 |
| JP2004516236A (ja) | 2004-06-03 |
| HU225874B1 (en) | 2007-11-28 |
| CZ20023778A3 (cs) | 2003-08-13 |
| CA2411369A1 (en) | 2001-11-22 |
| ATE345816T1 (de) | 2006-12-15 |
| EP1825864A3 (en) | 2007-09-12 |
| KR20070116192A (ko) | 2007-12-06 |
| CN100339132C (zh) | 2007-09-26 |
| IL152831A0 (en) | 2003-06-24 |
| NO20025463L (no) | 2003-01-09 |
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