KR20020027562A - 골절 치료용 약제 - Google Patents

골절 치료용 약제 Download PDF

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Publication number
KR20020027562A
KR20020027562A KR1020027002160A KR20027002160A KR20020027562A KR 20020027562 A KR20020027562 A KR 20020027562A KR 1020027002160 A KR1020027002160 A KR 1020027002160A KR 20027002160 A KR20027002160 A KR 20027002160A KR 20020027562 A KR20020027562 A KR 20020027562A
Authority
KR
South Korea
Prior art keywords
bone
bisphosphonate
group
medicament
stimulation
Prior art date
Application number
KR1020027002160A
Other languages
English (en)
Korean (ko)
Inventor
리틀데이비드지.
Original Assignee
더 로얄 알렉산드라 호스피탈 포 칠드런
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 더 로얄 알렉산드라 호스피탈 포 칠드런 filed Critical 더 로얄 알렉산드라 호스피탈 포 칠드런
Publication of KR20020027562A publication Critical patent/KR20020027562A/ko

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020027002160A 1999-08-19 2000-08-17 골절 치료용 약제 KR20020027562A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPQ2325 1999-08-19
AUPQ2325A AUPQ232599A0 (en) 1999-08-19 1999-08-19 Drug for treating fractures
PCT/AU2000/000982 WO2001013922A1 (en) 1999-08-19 2000-08-17 Drug for treating fractures

Publications (1)

Publication Number Publication Date
KR20020027562A true KR20020027562A (ko) 2002-04-13

Family

ID=3816500

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027002160A KR20020027562A (ko) 1999-08-19 2000-08-17 골절 치료용 약제

Country Status (16)

Country Link
EP (1) EP1214079A4 (pt)
JP (1) JP2003507426A (pt)
KR (1) KR20020027562A (pt)
CN (1) CN100345548C (pt)
AU (1) AUPQ232599A0 (pt)
BR (1) BR0013416A (pt)
CA (1) CA2381302A1 (pt)
HK (1) HK1048441B (pt)
HU (1) HUP0202396A3 (pt)
IL (1) IL148166A0 (pt)
NO (1) NO20020784D0 (pt)
NZ (1) NZ517538A (pt)
PL (1) PL353485A1 (pt)
SK (1) SK2382002A3 (pt)
WO (1) WO2001013922A1 (pt)
ZA (1) ZA200202160B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002221339B2 (en) 2001-02-06 2006-04-27 The Sydney Children's Hospitals Network (Randwick And Westmead) (Incorporating The Royal Alexandra Hospital For Children) A drug for the treatment of osteonecrosis and for the management of patients at risk of developing osteonecrosis
WO2002080933A1 (en) * 2001-04-03 2002-10-17 The Royal Alexandra Hospital For Children A drug for use in bone grafting
AUPR553701A0 (en) * 2001-06-07 2001-07-12 Royal Alexandra Hospital For Children, The A device for the delivery of a drug to a fractured bone
ES2561463T3 (es) * 2003-08-21 2016-02-26 Addbio Ab Dispositivo de implante recubierto con bisfosfonato y método para el mismo
JP2007505886A (ja) * 2003-09-19 2007-03-15 ファイザー・プロダクツ・インク 2−メチレン−19−ノル−ビタミンd誘導体及びビスホスフォネートの組み合わせを含む医薬組成物及び方法
ITMI20040218A1 (it) * 2004-02-10 2004-05-10 Abiogen Pharma Spa Uso di neridronato sodico per promuovere la neoformazione ossea
ITMI20040641A1 (it) * 2004-03-31 2004-06-30 Tb Technology S R L Composizioni bioadesive bifunzionali per implantologia orale
AR048742A1 (es) * 2004-12-22 2006-05-24 Gador Sa Sistema de aplicacion de medicamentos intra-oral
ES2379485T3 (es) * 2005-10-27 2012-04-26 Thommen Medical Ag Implante dental y procedimiento para su fabricación
US8882740B2 (en) 2009-12-23 2014-11-11 Stryker Trauma Gmbh Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR8107560A (pt) * 1981-11-19 1983-07-05 Luiz Romariz Duarte Estimulacao ultra-sonica da consolidacao de fraturas osseas
SK74594A3 (en) * 1991-12-17 1995-01-12 Procter & Gamble Pharma Treatment for treating of osteoporosis
EP0600834A1 (en) * 1992-11-30 1994-06-08 Ciba-Geigy Ag Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing
AU670337B2 (en) * 1992-11-30 1996-07-11 Novartis Ag Use of certain methanebisphosphonic acid derivatives in fracture healing
EP0675723A4 (en) * 1992-12-23 1998-08-05 Merck & Co Inc BIPHOSPHONATE / ESTROGEN THERAPY FOR TREATING AND PREVENTING BONE LOSS.
US5403829A (en) * 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
GB9408775D0 (en) * 1994-05-04 1994-06-22 Ciba Geigy Ag Use of certain methanebisphosphonic acid derivatives to prevent prothesis loosening and prothesis migration
WO1996039150A1 (en) * 1995-06-06 1996-12-12 Merck & Co., Inc. Bisphosphonate therapy for bone loss associated with rheumatoid arthritis
US5616571A (en) * 1995-06-06 1997-04-01 Merck & Co., Inc. Bisphosphonates prevent bone loss associated with immunosuppressive therapy
US5853759A (en) * 1996-05-17 1998-12-29 Merck & Co.. Inc. Effervescent alendronate formulation
GB9613722D0 (en) * 1996-06-28 1996-08-28 Univ Liverpool Chemical compounds

Also Published As

Publication number Publication date
NO20020784L (no) 2002-02-18
SK2382002A3 (en) 2002-09-10
JP2003507426A (ja) 2003-02-25
HK1048441A1 (en) 2003-04-04
HK1048441B (zh) 2008-02-22
PL353485A1 (en) 2003-11-17
AUPQ232599A0 (en) 1999-09-09
IL148166A0 (en) 2002-09-12
ZA200202160B (en) 2003-08-27
HUP0202396A3 (en) 2005-02-28
EP1214079A1 (en) 2002-06-19
BR0013416A (pt) 2002-04-30
CN100345548C (zh) 2007-10-31
HUP0202396A2 (hu) 2002-11-28
CA2381302A1 (en) 2001-03-01
EP1214079A4 (en) 2004-03-24
CN1370071A (zh) 2002-09-18
WO2001013922A1 (en) 2001-03-01
NZ517538A (en) 2003-07-25
NO20020784D0 (no) 2002-02-18

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Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application
J201 Request for trial against refusal decision
J301 Trial decision

Free format text: TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20070802

Effective date: 20080125