KR20010022672A - 4-[[(시아노이미노)[(1,2,2-트리메틸프로필)아미노]메틸]아미노]벤조나이트릴의 엔안티오머 - Google Patents

4-[[(시아노이미노)[(1,2,2-트리메틸프로필)아미노]메틸]아미노]벤조나이트릴의 엔안티오머 Download PDF

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Publication number
KR20010022672A
KR20010022672A KR1020007001267A KR20007001267A KR20010022672A KR 20010022672 A KR20010022672 A KR 20010022672A KR 1020007001267 A KR1020007001267 A KR 1020007001267A KR 20007001267 A KR20007001267 A KR 20007001267A KR 20010022672 A KR20010022672 A KR 20010022672A
Authority
KR
South Korea
Prior art keywords
enantiomer
amino
enantiomers
trimethylpropyl
cyanoimino
Prior art date
Application number
KR1020007001267A
Other languages
English (en)
Korean (ko)
Inventor
에트월카네일에스.
Original Assignee
말라테스티닉 니콜라스 피.
브리스톨-마이어즈 스퀴브 컴페니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 말라테스티닉 니콜라스 피., 브리스톨-마이어즈 스퀴브 컴페니 filed Critical 말라테스티닉 니콜라스 피.
Publication of KR20010022672A publication Critical patent/KR20010022672A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43—Guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
KR1020007001267A 1997-08-13 1998-08-03 4-[[(시아노이미노)[(1,2,2-트리메틸프로필)아미노]메틸]아미노]벤조나이트릴의 엔안티오머 KR20010022672A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5556897P 1997-08-13 1997-08-13
US60/055,568 1997-08-13
US7136498P 1998-01-15 1998-01-15
US60/071,364 1998-01-15
PCT/US1998/016015 WO1999008673A1 (en) 1997-08-13 1998-08-03 Enantiomers of 4-[[(cyanoimino)- [(1,2,2-trimethylpropyl) amino]methyl]amino] benzonitrile

Publications (1)

Publication Number Publication Date
KR20010022672A true KR20010022672A (ko) 2001-03-26

Family

ID=26734360

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007001267A KR20010022672A (ko) 1997-08-13 1998-08-03 4-[[(시아노이미노)[(1,2,2-트리메틸프로필)아미노]메틸]아미노]벤조나이트릴의 엔안티오머

Country Status (20)

Country Link
US (3) US6013668A (es)
EP (1) EP1003502A4 (es)
JP (1) JP2001515034A (es)
KR (1) KR20010022672A (es)
CN (1) CN1265589A (es)
AR (1) AR015149A1 (es)
AU (1) AU736687B2 (es)
BR (1) BR9811485A (es)
CA (1) CA2300414A1 (es)
CO (1) CO4750804A1 (es)
HU (1) HUP0003417A3 (es)
ID (1) ID24267A (es)
IL (1) IL133826A0 (es)
NO (1) NO20000686L (es)
NZ (1) NZ502125A (es)
PE (1) PE109199A1 (es)
PL (1) PL338668A1 (es)
TR (1) TR200000343T2 (es)
UY (1) UY25129A1 (es)
WO (1) WO1999008673A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458835B2 (en) * 1997-08-13 2002-10-01 Bristol-Myers Squibb Company Method of inhibiting or treating chemotherapy-induced hair loss
CN100475781C (zh) * 2004-02-13 2009-04-08 沃尼尔·朗伯有限责任公司 雄激素受体调节剂
JP3997255B2 (ja) * 2004-02-13 2007-10-24 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー アンドロゲンレセプターモジュレーター
US7507860B2 (en) 2004-04-13 2009-03-24 Pfizer Inc. Androgen modulators
WO2005102990A1 (en) 2004-04-22 2005-11-03 Warner-Lambert Company Llc Androgen modulators
BRPI0513020A (pt) 2004-07-08 2008-04-22 Warner Lambert Co moduladores de andrÈgenio, seus usos, composição farmacêutica, formulação farmacêutica tópica e artigo de fabricação
TW200724139A (en) 2005-05-05 2007-07-01 Warner Lambert Co Androgen modulators
CN108440307B (zh) * 2018-04-16 2020-11-17 浙江工业大学 一种手性胺类化合物的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1489879A (en) * 1974-12-20 1977-10-26 Leo Pharm Prod Ltd N'-cyano-n'-3-pyridylguanidines
US4139619A (en) * 1976-05-24 1979-02-13 The Upjohn Company 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth
US4596812A (en) * 1976-05-24 1986-06-24 The Upjohn Company Methods and solutions for treating male pattern alopecia
US5244664A (en) * 1988-01-21 1993-09-14 Leo Pharmaceutical Products Ltd. Topical preparation for treatment of alopecia
US5011837A (en) * 1988-08-09 1991-04-30 E. R. Squibb & Sons, Inc. Aryl cyanoguanidines: potassium channel activators and method of making same
GB8908063D0 (en) * 1989-04-11 1989-05-24 Beecham Group Plc Novel compounds
CA2085605C (en) * 1990-08-10 2003-03-11 Arthur Robert Diani Stimulation of hair growth with potassium channel openers and 5alpha-reductase inhibitors
AU9059591A (en) * 1990-11-29 1992-06-25 Upjohn Company, The Stimulation of hair growth with potassium channel openers and an androgen receptor blocker
USH1480H (en) * 1993-12-09 1995-09-05 The Procter & Gamble Company Methods of using dyphylline for the promotion of hair growth
FR2740331B1 (fr) * 1995-10-25 1997-12-19 Sederma Sa Nouvelles compositions cosmetiques pour le traitement des cheveux et du cuir chevelu

Also Published As

Publication number Publication date
US6472427B1 (en) 2002-10-29
CN1265589A (zh) 2000-09-06
ID24267A (id) 2000-07-13
EP1003502A1 (en) 2000-05-31
US6013668A (en) 2000-01-11
BR9811485A (pt) 2000-09-19
EP1003502A4 (en) 2000-06-07
NO20000686L (no) 2000-03-31
NO20000686D0 (no) 2000-02-11
CA2300414A1 (en) 1999-02-25
UY25129A1 (es) 2000-12-29
TR200000343T2 (tr) 2000-08-21
AU736687B2 (en) 2001-08-02
PL338668A1 (en) 2000-11-20
HUP0003417A3 (en) 2002-11-28
AR015149A1 (es) 2001-04-18
CO4750804A1 (es) 1999-03-31
HUP0003417A2 (hu) 2001-02-28
US6262122B1 (en) 2001-07-17
PE109199A1 (es) 2000-01-30
AU8680898A (en) 1999-03-08
IL133826A0 (en) 2001-04-30
WO1999008673A1 (en) 1999-02-25
JP2001515034A (ja) 2001-09-18
NZ502125A (en) 2001-08-31

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