KR20010013101A - 인간 시상하부 기능 변경의 신경화학적 개시제로서의19-노르-콜란 스테로이드 - Google Patents

인간 시상하부 기능 변경의 신경화학적 개시제로서의19-노르-콜란 스테로이드 Download PDF

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Publication number
KR20010013101A
KR20010013101A KR19997011080A KR19997011080A KR20010013101A KR 20010013101 A KR20010013101 A KR 20010013101A KR 19997011080 A KR19997011080 A KR 19997011080A KR 19997011080 A KR19997011080 A KR 19997011080A KR 20010013101 A KR20010013101 A KR 20010013101A
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KR
South Korea
Prior art keywords
hydrogen
methyl
double bond
hydroxy
absent
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KR19997011080A
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English (en)
Korean (ko)
Inventor
클리브 엘. 제닝스-화이트
데이비드 엘. 베르리너
나탄 더블유. 아담스
Original Assignee
케빈 맥카티
페린 파마슈티칼스, 인코오포레이티드
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Application filed by 케빈 맥카티, 페린 파마슈티칼스, 인코오포레이티드 filed Critical 케빈 맥카티
Publication of KR20010013101A publication Critical patent/KR20010013101A/ko

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L21/00—Processes or apparatus adapted for the manufacture or treatment of semiconductor or solid state devices or of parts thereof
    • H01L21/02—Manufacture or treatment of semiconductor devices or of parts thereof
    • H01L21/027—Making masks on semiconductor bodies for further photolithographic processing not provided for in group H01L21/18 or H01L21/34

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Manufacturing & Machinery (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Computer Hardware Design (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Power Engineering (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR19997011080A 1996-06-07 1997-06-09 인간 시상하부 기능 변경의 신경화학적 개시제로서의19-노르-콜란 스테로이드 KR20010013101A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/660,804 US5922699A (en) 1996-06-07 1996-06-07 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
PCT/US1997/009992 WO1997046574A1 (fr) 1996-06-07 1997-06-09 Steroïdes de 19-nor-cholane utiles comme initiateurs neurochimiques d'une modification de la fonction hypothalamique humaine

Publications (1)

Publication Number Publication Date
KR20010013101A true KR20010013101A (ko) 2001-02-26

Family

ID=24651031

Family Applications (1)

Application Number Title Priority Date Filing Date
KR19997011080A KR20010013101A (ko) 1996-06-07 1997-06-09 인간 시상하부 기능 변경의 신경화학적 개시제로서의19-노르-콜란 스테로이드

Country Status (11)

Country Link
US (3) US5922699A (fr)
EP (1) EP0948521A4 (fr)
KR (1) KR20010013101A (fr)
AU (1) AU732960B2 (fr)
BG (1) BG62936B1 (fr)
CA (1) CA2258177C (fr)
HU (1) HUP9903432A3 (fr)
NO (1) NO990498D0 (fr)
NZ (1) NZ333548A (fr)
PL (1) PL331522A1 (fr)
WO (1) WO1997046574A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922699A (en) 1996-06-07 1999-07-13 Pherin Corporation 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
BR9711812A (pt) * 1996-07-23 1999-08-24 Pherin Pharm Inc EsterÄides como estimuladores neuroqu¡micos do ÄrgÆo vomeronasal para aliviar os sintomas de pms e ansiedade
FR2791572A1 (fr) * 1999-03-31 2000-10-06 Adir Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables
US6806293B1 (en) * 2001-03-12 2004-10-19 Darley Pharmaceuticals Ltd Use of pheromone compounds having MAP kinase modulating activity
CA2451992C (fr) 2001-05-15 2013-08-27 Psychogenics Inc. Systemes et procedes de surveillance d'informatique comportementale
DE10335845B4 (de) * 2003-05-09 2006-08-31 Müller, Martina, Dr.med. Pheromone als Antikrebsmittel
EP1789056A1 (fr) * 2004-06-29 2007-05-30 Jado Technologies GmbH Utilisation de compositions pharmaceutiques derivees de steroides pour le traitement de troubles associes a des processus pathologiques dans les radeaux lipidiques
US20070048230A1 (en) * 2005-08-24 2007-03-01 Walter Parsadayan Pheromone compositions and methods
DE102020204507A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Weichspüler mit aphrodisierend wirkenden Duftstoffen
DE102020204506A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Weichspüler mit Pheromonen
DE102020204509A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Waschmittel mit Pheromonen
DE102020204505A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Wasch-/Pflegeartikel umfassend Pheromone

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH455765A (de) * 1958-04-12 1968-05-15 Philips Nv Verfahren zur Herstellung neuer Steroide
US3492318A (en) 1968-01-22 1970-01-27 Syntex Corp Cyclopropenyl androstanes
US3946052A (en) 1975-06-16 1976-03-23 Stanford Research Institute 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs thereof having postcoital antifertility activity
US5155045A (en) 1985-01-25 1992-10-13 Trustees Of The University Of Penn. Use of male essence to alter female endocrine response
US5223492A (en) * 1987-10-27 1993-06-29 Nasraoui Nejib M Derivatives of 19-nor progesterone; process for producing them and the pharmaceutical compositions incorporating them
FR2637803B1 (fr) * 1988-10-19 1993-07-09 Ire Celltarg Sa Ligands specifiques de recepteurs d'hormones steroides estrogenes et progestagenes, application et produits intermediaires de synthese
JP2578369B2 (ja) 1989-05-09 1997-02-05 ポーラ化成工業株式会社 芳香組成物
US5969168A (en) * 1991-01-07 1999-10-19 Pherin Corporation Androstanes for inducing hypothalamic effects
US5272134A (en) * 1992-03-24 1993-12-21 Erox Corporation Fragrance compositions and other compositions which contain human pheromones
AU698834B2 (en) * 1993-05-24 1998-11-12 Purdue Pharma Ltd. Methods and compositions for inducing sleep
BR9307866A (pt) * 1993-06-15 1996-07-30 Pherin Corp Esteróides estreno como iniciadores neuroquímicos de mudança em funçao hipotalamica humana e composiçoes farmaceuticas relacionadas e processos
ES2210243T3 (es) * 1993-06-15 2004-07-01 Pherin Corporation Esteroides de androstano utiles como iniciadores del cambio de la funcion hipotalamica humana, composiciones farmaceuticas y procedimientos asociados.
KR970700199A (ko) * 1994-01-06 1997-01-08 에드워드 이. 데이비스 신규한 항남성호르몬제 및 이와 관련된 조성물 및 사용방법(novel antiandrogenic agents and related pharmaceutical compositions and methods of use)
US5563131A (en) * 1994-08-04 1996-10-08 Pherin Corporation Pregnane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US5792757A (en) * 1994-08-04 1998-08-11 Pherin Pharmaceuticals 19-nor-pregnane steroids as neurochemical initiators of change in human hypothalamic function
US6066627A (en) * 1994-08-04 2000-05-23 Pherin Corporation Steroids as neurochemical initiators of change in human blood levels of LH
NZ294510A (en) * 1994-09-29 1999-04-29 Pherin Corp Estrene steroids which bind to neuroepithelial receptors changing hypothalamic function
WO1996040421A1 (fr) 1995-06-07 1996-12-19 Memtec America Corporation Membranes de microfiltration a haute densite de pores et structure mixte isotrope et anisotrope
US5922699A (en) 1996-06-07 1999-07-13 Pherin Corporation 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
BR9711812A (pt) * 1996-07-23 1999-08-24 Pherin Pharm Inc EsterÄides como estimuladores neuroqu¡micos do ÄrgÆo vomeronasal para aliviar os sintomas de pms e ansiedade

Also Published As

Publication number Publication date
BG103060A (en) 1999-10-29
AU732960B2 (en) 2001-05-03
US5922699A (en) 1999-07-13
US6437156B1 (en) 2002-08-20
WO1997046574A1 (fr) 1997-12-11
HUP9903432A3 (en) 2000-04-28
PL331522A1 (en) 1999-07-19
NO990498L (no) 1999-02-03
CA2258177C (fr) 2007-05-08
EP0948521A4 (fr) 2007-01-31
HUP9903432A2 (hu) 2000-03-28
EP0948521A1 (fr) 1999-10-13
NZ333548A (en) 2000-06-23
CA2258177A1 (fr) 1997-12-11
BG62936B1 (bg) 2000-11-30
NO990498D0 (no) 1999-02-03
US6432938B1 (en) 2002-08-13
AU3307397A (en) 1998-01-05

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