HUP9903432A2 - 19-Norkolán szteroidok mint a humán hipotalamusz működésében változást okozó neurokémiai iniciátorok - Google Patents

19-Norkolán szteroidok mint a humán hipotalamusz működésében változást okozó neurokémiai iniciátorok

Info

Publication number
HUP9903432A2
HUP9903432A2 HU9903432A HUP9903432A HUP9903432A2 HU P9903432 A2 HUP9903432 A2 HU P9903432A2 HU 9903432 A HU9903432 A HU 9903432A HU P9903432 A HUP9903432 A HU P9903432A HU P9903432 A2 HUP9903432 A2 HU P9903432A2
Authority
HU
Hungary
Prior art keywords
change
hypothalamic function
vömeroferin
human hypothalamic
neurochemical initiators
Prior art date
Application number
HU9903432A
Other languages
English (en)
Inventor
Nathan W. Adams
David L. Berliner
Clive L. Jennings-White
Original Assignee
Pherin Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pherin Pharmaceuticals, Inc. filed Critical Pherin Pharmaceuticals, Inc.
Publication of HUP9903432A2 publication Critical patent/HUP9903432A2/hu
Publication of HUP9903432A3 publication Critical patent/HUP9903432A3/hu

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L21/00—Processes or apparatus adapted for the manufacture or treatment of semiconductor or solid state devices or of parts thereof
    • H01L21/02—Manufacture or treatment of semiconductor devices or of parts thereof
    • H01L21/027—Making masks on semiconductor bodies for further photolithographic processing not provided for in group H01L21/18 or H01L21/34

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Manufacturing & Machinery (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Computer Hardware Design (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Power Engineering (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

A találmány egy egyedben a hipőtalaműsz működésének megváltőztatásáraalkalmas készítményre és új 19-nőrkőlin-származékőkra vőnatkőzik. Akészítmény egy hűmán vőmerőferint, példáűl egy 19-nőrkőlán szterőidőtvagy egy vőmerőferint tartalmaz, és nazálisan adagőlható és a kezeléssőrán a vőmerőferin egy specifikűs neűrőepiteliális receptőrhőzkötődik. ŕ
HU9903432A 1996-06-07 1997-06-09 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function HUP9903432A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/660,804 US5922699A (en) 1996-06-07 1996-06-07 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
PCT/US1997/009992 WO1997046574A1 (en) 1996-06-07 1997-06-09 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function

Publications (2)

Publication Number Publication Date
HUP9903432A2 true HUP9903432A2 (hu) 2000-03-28
HUP9903432A3 HUP9903432A3 (en) 2000-04-28

Family

ID=24651031

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903432A HUP9903432A3 (en) 1996-06-07 1997-06-09 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function

Country Status (11)

Country Link
US (3) US5922699A (hu)
EP (1) EP0948521A4 (hu)
KR (1) KR20010013101A (hu)
AU (1) AU732960B2 (hu)
BG (1) BG62936B1 (hu)
CA (1) CA2258177C (hu)
HU (1) HUP9903432A3 (hu)
NO (1) NO990498D0 (hu)
NZ (1) NZ333548A (hu)
PL (1) PL331522A1 (hu)
WO (1) WO1997046574A1 (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922699A (en) 1996-06-07 1999-07-13 Pherin Corporation 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
BR9711812A (pt) * 1996-07-23 1999-08-24 Pherin Pharm Inc EsterÄides como estimuladores neuroqu¡micos do ÄrgÆo vomeronasal para aliviar os sintomas de pms e ansiedade
FR2791572A1 (fr) * 1999-03-31 2000-10-06 Adir Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables
US6806293B1 (en) * 2001-03-12 2004-10-19 Darley Pharmaceuticals Ltd Use of pheromone compounds having MAP kinase modulating activity
CA2451992C (en) 2001-05-15 2013-08-27 Psychogenics Inc. Systems and methods for monitoring behavior informatics
DE10335845B4 (de) * 2003-05-09 2006-08-31 Müller, Martina, Dr.med. Pheromone als Antikrebsmittel
EP1789056A1 (en) * 2004-06-29 2007-05-30 Jado Technologies GmbH Use of steroid-derived pharmaceutical compositions for treating disorders relating to pathological processes in lipid rafts
US20070048230A1 (en) * 2005-08-24 2007-03-01 Walter Parsadayan Pheromone compositions and methods
DE102020204507A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Weichspüler mit aphrodisierend wirkenden Duftstoffen
DE102020204506A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Weichspüler mit Pheromonen
DE102020204509A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Waschmittel mit Pheromonen
DE102020204505A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Wasch-/Pflegeartikel umfassend Pheromone

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH455765A (de) * 1958-04-12 1968-05-15 Philips Nv Verfahren zur Herstellung neuer Steroide
US3492318A (en) 1968-01-22 1970-01-27 Syntex Corp Cyclopropenyl androstanes
US3946052A (en) 1975-06-16 1976-03-23 Stanford Research Institute 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs thereof having postcoital antifertility activity
US5155045A (en) 1985-01-25 1992-10-13 Trustees Of The University Of Penn. Use of male essence to alter female endocrine response
US5223492A (en) * 1987-10-27 1993-06-29 Nasraoui Nejib M Derivatives of 19-nor progesterone; process for producing them and the pharmaceutical compositions incorporating them
FR2637803B1 (fr) * 1988-10-19 1993-07-09 Ire Celltarg Sa Ligands specifiques de recepteurs d'hormones steroides estrogenes et progestagenes, application et produits intermediaires de synthese
JP2578369B2 (ja) 1989-05-09 1997-02-05 ポーラ化成工業株式会社 芳香組成物
US5969168A (en) * 1991-01-07 1999-10-19 Pherin Corporation Androstanes for inducing hypothalamic effects
US5272134A (en) * 1992-03-24 1993-12-21 Erox Corporation Fragrance compositions and other compositions which contain human pheromones
AU698834B2 (en) * 1993-05-24 1998-11-12 Purdue Pharma Ltd. Methods and compositions for inducing sleep
BR9307866A (pt) * 1993-06-15 1996-07-30 Pherin Corp Esteróides estreno como iniciadores neuroquímicos de mudança em funçao hipotalamica humana e composiçoes farmaceuticas relacionadas e processos
ES2210243T3 (es) * 1993-06-15 2004-07-01 Pherin Corporation Esteroides de androstano utiles como iniciadores del cambio de la funcion hipotalamica humana, composiciones farmaceuticas y procedimientos asociados.
KR970700199A (ko) * 1994-01-06 1997-01-08 에드워드 이. 데이비스 신규한 항남성호르몬제 및 이와 관련된 조성물 및 사용방법(novel antiandrogenic agents and related pharmaceutical compositions and methods of use)
US5563131A (en) * 1994-08-04 1996-10-08 Pherin Corporation Pregnane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US5792757A (en) * 1994-08-04 1998-08-11 Pherin Pharmaceuticals 19-nor-pregnane steroids as neurochemical initiators of change in human hypothalamic function
US6066627A (en) * 1994-08-04 2000-05-23 Pherin Corporation Steroids as neurochemical initiators of change in human blood levels of LH
NZ294510A (en) * 1994-09-29 1999-04-29 Pherin Corp Estrene steroids which bind to neuroepithelial receptors changing hypothalamic function
WO1996040421A1 (en) 1995-06-07 1996-12-19 Memtec America Corporation Microfiltration membranes having high pore density and mixed isotropic and anisotropic structure
US5922699A (en) 1996-06-07 1999-07-13 Pherin Corporation 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
BR9711812A (pt) * 1996-07-23 1999-08-24 Pherin Pharm Inc EsterÄides como estimuladores neuroqu¡micos do ÄrgÆo vomeronasal para aliviar os sintomas de pms e ansiedade

Also Published As

Publication number Publication date
BG103060A (en) 1999-10-29
AU732960B2 (en) 2001-05-03
US5922699A (en) 1999-07-13
KR20010013101A (ko) 2001-02-26
US6437156B1 (en) 2002-08-20
WO1997046574A1 (en) 1997-12-11
HUP9903432A3 (en) 2000-04-28
PL331522A1 (en) 1999-07-19
NO990498L (no) 1999-02-03
CA2258177C (en) 2007-05-08
EP0948521A4 (en) 2007-01-31
EP0948521A1 (en) 1999-10-13
NZ333548A (en) 2000-06-23
CA2258177A1 (en) 1997-12-11
BG62936B1 (bg) 2000-11-30
NO990498D0 (no) 1999-02-03
US6432938B1 (en) 2002-08-13
AU3307397A (en) 1998-01-05

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