BG62936B1 - 19-нор-холан стероиди като неврохимични инициатори на промяната в действието на хипоталамуса при човек - Google Patents

19-нор-холан стероиди като неврохимични инициатори на промяната в действието на хипоталамуса при човек Download PDF

Info

Publication number
BG62936B1
BG62936B1 BG103060A BG10306099A BG62936B1 BG 62936 B1 BG62936 B1 BG 62936B1 BG 103060 A BG103060 A BG 103060A BG 10306099 A BG10306099 A BG 10306099A BG 62936 B1 BG62936 B1 BG 62936B1
Authority
BG
Bulgaria
Prior art keywords
hydrogen
methyl
hydroxy
double bond
individual
Prior art date
Application number
BG103060A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG103060A (en
Inventor
Clive Jennings-White
David Berliner
Nathan W. Adams
Original Assignee
Pherin Pharmaceuticals, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pherin Pharmaceuticals, Inc filed Critical Pherin Pharmaceuticals, Inc
Publication of BG103060A publication Critical patent/BG103060A/xx
Publication of BG62936B1 publication Critical patent/BG62936B1/bg

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L21/00—Processes or apparatus adapted for the manufacture or treatment of semiconductor or solid state devices or of parts thereof
    • H01L21/02—Manufacture or treatment of semiconductor devices or of parts thereof
    • H01L21/027—Making masks on semiconductor bodies for further photolithographic processing not provided for in group H01L21/18 or H01L21/34

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Manufacturing & Machinery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Computer Hardware Design (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Power Engineering (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BG103060A 1996-06-07 1999-01-07 19-нор-холан стероиди като неврохимични инициатори на промяната в действието на хипоталамуса при човек BG62936B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/660,804 US5922699A (en) 1996-06-07 1996-06-07 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
PCT/US1997/009992 WO1997046574A1 (en) 1996-06-07 1997-06-09 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function

Publications (2)

Publication Number Publication Date
BG103060A BG103060A (en) 1999-10-29
BG62936B1 true BG62936B1 (bg) 2000-11-30

Family

ID=24651031

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103060A BG62936B1 (bg) 1996-06-07 1999-01-07 19-нор-холан стероиди като неврохимични инициатори на промяната в действието на хипоталамуса при човек

Country Status (11)

Country Link
US (3) US5922699A (hu)
EP (1) EP0948521A4 (hu)
KR (1) KR20010013101A (hu)
AU (1) AU732960B2 (hu)
BG (1) BG62936B1 (hu)
CA (1) CA2258177C (hu)
HU (1) HUP9903432A3 (hu)
NO (1) NO990498D0 (hu)
NZ (1) NZ333548A (hu)
PL (1) PL331522A1 (hu)
WO (1) WO1997046574A1 (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922699A (en) 1996-06-07 1999-07-13 Pherin Corporation 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
PL331357A1 (en) * 1996-07-23 1999-07-05 Pherin Pharmaceuticals Steroids as neurochemical vno stimulators for soothing the symptoms of premenstrual tension and anxiety
FR2791572A1 (fr) * 1999-03-31 2000-10-06 Adir Utilisation d'hormones sexuelles pour l'obtention d'une composition pharmaceutique nasale utile pour le traitement des saignements uterins indesirables
US6806293B1 (en) * 2001-03-12 2004-10-19 Darley Pharmaceuticals Ltd Use of pheromone compounds having MAP kinase modulating activity
US7269516B2 (en) * 2001-05-15 2007-09-11 Psychogenics, Inc. Systems and methods for monitoring behavior informatics
DE10335845B4 (de) * 2003-05-09 2006-08-31 Müller, Martina, Dr.med. Pheromone als Antikrebsmittel
CA2571440A1 (en) * 2004-06-29 2006-01-12 Jadolabs Gmbh Use of steroid-derived pharmaceutical compositions for treating disorders relating to pathological processes in lipid rafts
US20070048230A1 (en) * 2005-08-24 2007-03-01 Walter Parsadayan Pheromone compositions and methods
DE102020204507A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Weichspüler mit aphrodisierend wirkenden Duftstoffen
DE102020204509A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Waschmittel mit Pheromonen
DE102020204506A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Weichspüler mit Pheromonen
DE102020204505A1 (de) 2020-04-07 2021-10-07 Henkel Ag & Co. Kgaa Wasch-/Pflegeartikel umfassend Pheromone

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH432506A (de) * 1958-04-12 1967-03-31 Philips Nv Verfahren zur Herstellung neuer Steroide
US3492318A (en) 1968-01-22 1970-01-27 Syntex Corp Cyclopropenyl androstanes
US3946052A (en) 1975-06-16 1976-03-23 Stanford Research Institute 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs thereof having postcoital antifertility activity
US5155045A (en) 1985-01-25 1992-10-13 Trustees Of The University Of Penn. Use of male essence to alter female endocrine response
US5223492A (en) * 1987-10-27 1993-06-29 Nasraoui Nejib M Derivatives of 19-nor progesterone; process for producing them and the pharmaceutical compositions incorporating them
FR2637803B1 (fr) * 1988-10-19 1993-07-09 Ire Celltarg Sa Ligands specifiques de recepteurs d'hormones steroides estrogenes et progestagenes, application et produits intermediaires de synthese
JP2578369B2 (ja) 1989-05-09 1997-02-05 ポーラ化成工業株式会社 芳香組成物
US5969168A (en) * 1991-01-07 1999-10-19 Pherin Corporation Androstanes for inducing hypothalamic effects
US5272134A (en) * 1992-03-24 1993-12-21 Erox Corporation Fragrance compositions and other compositions which contain human pheromones
AU698834B2 (en) * 1993-05-24 1998-11-12 Purdue Pharma Ltd. Methods and compositions for inducing sleep
HUT74172A (en) * 1993-06-15 1996-11-28 Pherin Corp Androstane steroids as neurochemical initilators of change in human hypothalamic function and pharmaceutical compositions containing them
CA2165324A1 (en) * 1993-06-15 1994-12-22 David L. Berliner Estrene steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
WO1995018821A2 (en) * 1994-01-06 1995-07-13 Sri International Novel antiandrogenic agents and related pharmaceutical compositions and methods of use
US5563131A (en) * 1994-08-04 1996-10-08 Pherin Corporation Pregnane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US5792757A (en) * 1994-08-04 1998-08-11 Pherin Pharmaceuticals 19-nor-pregnane steroids as neurochemical initiators of change in human hypothalamic function
US6066627A (en) * 1994-08-04 2000-05-23 Pherin Corporation Steroids as neurochemical initiators of change in human blood levels of LH
PL319601A1 (en) * 1994-09-29 1997-08-18 Pherin Corp Hypothalamus action stimulating novel estrenes
WO1996040421A1 (en) 1995-06-07 1996-12-19 Memtec America Corporation Microfiltration membranes having high pore density and mixed isotropic and anisotropic structure
US5922699A (en) 1996-06-07 1999-07-13 Pherin Corporation 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
PL331357A1 (en) * 1996-07-23 1999-07-05 Pherin Pharmaceuticals Steroids as neurochemical vno stimulators for soothing the symptoms of premenstrual tension and anxiety

Also Published As

Publication number Publication date
NZ333548A (en) 2000-06-23
NO990498L (no) 1999-02-03
KR20010013101A (ko) 2001-02-26
US6437156B1 (en) 2002-08-20
HUP9903432A3 (en) 2000-04-28
US6432938B1 (en) 2002-08-13
CA2258177A1 (en) 1997-12-11
CA2258177C (en) 2007-05-08
US5922699A (en) 1999-07-13
AU732960B2 (en) 2001-05-03
EP0948521A1 (en) 1999-10-13
WO1997046574A1 (en) 1997-12-11
NO990498D0 (no) 1999-02-03
PL331522A1 (en) 1999-07-19
EP0948521A4 (en) 2007-01-31
HUP9903432A2 (hu) 2000-03-28
AU3307397A (en) 1998-01-05
BG103060A (en) 1999-10-29

Similar Documents

Publication Publication Date Title
EP0830369B1 (en) Nor-pregnanes for inducing hypothalamic effects
WO1996040727A9 (en) Novel nor-pregnanes for inducing hypothalamic effects
AU3206495A (en) Pregnanes and cholanes as neurochemical initiators of change in hypothalamic function
BG62936B1 (bg) 19-нор-холан стероиди като неврохимични инициатори на промяната в действието на хипоталамуса при човек
US5883087A (en) Androstane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
EP1340502A2 (en) Androstane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
WO1997046574A9 (en) 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
CZ92597A3 (en) Novel androstanes for inducing hypothalamic effects
EP0783513A1 (en) Novel estrenes for inducing hypothalamic effects
US6352980B1 (en) Estrenes for inducting hypothalamic effects
US5783571A (en) Method of altering hypothalamic function by nasal administration of estrene steroids
NZ291056A (en) Pregnanes and cholanes as neurochemical initiators of change in hypothalamic function
AU691474C (en) Androstane steroids as neurochemical initiators of change inhuman hypothalamic function and related pharmaceutical compositions and methods
US20020143001A1 (en) Androstane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US20020103391A1 (en) Novel androstanes for inducing hypothalamic effects