KR20000072134A - Health food for anticancer - Google Patents

Abstract

PURPOSE: Method for preparing a health food for anti-cancer using the extract of Ganoderma lucidum and grubs which are bred by a feed made of natural medicines and yellow soil is provided. CONSTITUTION: A feed for breeding grubs comprises powdered Cudrania tricuspidata 10wt.%, powdered Ulmus davidiana var. japonica 10wt.%, powdered Euonymus sieboldianus Blume 5wt.%, powdered Houttuyniae Herba 5wt%, powdered mistletoe 5wt.%, powdered wax gourd seed 2wt.%, powdered Smilax root 6wt.%, powdered Eriobotrya japonica 5wt.%, extract of a stem of oriental melon 3wt.%, extract of Cinnabaris 4wt.%, and yellow soil 45wt.%. The health food comprises 50wt.% of the extract obtained by extracting in hot water grubs bred by the prepared feed at 5-6°C for 36-42 months, and 50wt.% of the extract of Ganoderma lucidum cultivated in the composition composed of the natural medicines having the same ratio as the feed.

Description

Health food for anticancer}

In the present invention, by applying a medicinal composition consisting of a number of natural herbs and ocher with excellent anti-cancer or related pharmacological action as feed, the hydrothermal leaching extracts from slugs cultured, and Ganoderma lucidum grown in the medicinal composition It relates to a health food consisting of leached extract.

As interest in health and awareness of natural medicines change, interest in health foods manufactured by applying natural medicines is increasing, and among them, demand for health foods having excellent anticancer activity is increasing.

Conventional anticancer health food extracts a single anticancer natural medicine with excellent anticancer pharmacological action as it is, and is processed in the form of powder, pills, extracts, and the like. It is manufactured because a single type of natural medicine is limited in pharmacological action related to anticancer activity, and thus lacks the effect of treating various symptoms related to cancer.In general, natural medicines contain their own toxicity and inherent toxicity. If you take a health food extracted from its natural state, there is a problem that can have side effects.

It is an object of the present invention to provide anti-cancer health foods that are excellent in anti-cancer and related actions and have no side effects on the human body by neutralizing or eliminating the toxicity contained in the medicines while maintaining the anti-cancer and related actions of many natural medicinal products. have.

The present invention is applied to the medicinal composition consisting of a number of natural medicinal herbs and ocher with excellent anti-cancer or various pharmacological action associated with the feed cultivation of slugs and the extract of the slugs hydrothermally leached the slugs, and the medicinal herbs It is intended to neutralize or eliminate the toxicity of the medicinal herb while maintaining the anticancer and related actions of the natural medicinal herbs by mixing the Ganoderma lucidum mycelium into the composition by mixing the Ganoderma lucidum extract obtained by hydrothermal leaching the Ganoderma lucidum mushroom.

In order to construct the present invention, it is necessary to apply medicinal herbs to treat various symptoms such as glucose, jaundice and the like accompanying cancer, as well as anticancer action to inhibit or eliminate cancer cells. Natural medicinal herbs applied to the medicinal composition has to be applied to various kinds of natural medicinal herbs in order to exert not only anti-cancer action, but also pharmacological action to treat the symptoms associated with each other, and toxins contained in each natural medicinal herb to neutralize or eliminate, By applying the medicinal composition as a feed and culturing slugs, the medicinal properties of the medicinal herbs are stored in the slug's body and the toxicity is neutralized or eliminated in the slug's body.

Natural herbs to satisfy the above conditions is a certain amount of Guji mulberry, elm, sesame, shitta melon tap, lotus, Echocho, mistletoe, copper and seeds, powdered and mixed with a considerable amount of humidity To incubate the slugs and the incubation period of the slugs requires a certain time.

As described above, the incubation time of the slugs requires a time for the slugs to imply high concentrations of weakness in the body and a minimum time for eliminating the toxicity of the medicines. One slug is to provide maximum weakness. As described above, the minimum time that slugs have the greatest weakness requires 36 months to 42 months.

In the general conditions of slugs, slugs are only maintained for about 24 months, so the general weakness cannot be expected in slugs under normal living conditions. To satisfy the above conditions, slugs are maintained by maintaining a constant temperature during the incubation period. Inhibits growth of slugs and increases the incubation period of slugs.

Natural medicinal herbs such as Koji mulberry powder, elm powder, sesame tree powder, eochocho powder, mistletoe powder, copper seed powder, persimmon root powder, loquat powder, overextract extract, rosacea extract, A slug extract extracted by leaching slugs (Cicada, Scarab, Stag beetle, Mulberry moth larva) cultivated by applying the medicinal composition composed by applying ocher as a base in hot water, and Ganoderma lucidum mycelium in the medicinal composition Provided is an anti-cancer health food consisting of a mixture of Ganoderma lucidum extract extracted by leaching the Ganoderma lucidum cultivated by injection in hot water.

1. Guji mulberry according to the cheongmyeoncho, Guji mulberry has a flat (sex) sex, bitter taste, clean () mature) and mass blood (凉血).

The original plant is the old mulberry tree of the mulberry family and uses wood, root, cheonpaseok, bark, stems, leaves and fruits as medicines, and the root contains flavonoids, glycosides, amino acids, organic acids, sugars, molines, etc. Explaining.

Pharmacology breaks blood (혈), through menstruation, governs imak (淋 濁), eliminates the formation of old blood and stone (結石).

Strengthen the musculature (筋骨) and is active (blood).

It governs the wife's middle blood.

Pharmacology of the old tree,

Iii. Flavones and ethanol extracts from woody, rhizome, and woody forests are 30% inhibitory to white meat and uterine cancer.

Iii. In vitro experiments showed cytotoxicity to esophageal cancer cells.

Iii. The analgesic effect was observed in the white dough by nirvana method.

2. Elm has tannin, catechin, and apiofuranoside, and its weakness is Gapyeong.

Pharmacology of the elm tree is unknown, but its application is used in Lisu, expectoration, insomnia, and small species. It is easy.

3. A true bark tree is called an arrow tree and its branches are used as medicines. The components are chrysanthemin, benzoic acid, friedelanol, epiprideranol, Dulcitol and the like.

Pharmacology of the bark,

It is effective in reducing blood sugar and urine glucose, weight gain, and Langerhans beta proliferation, and is applied to neuralgia, hemostasis, dysmenorrhea, and cancer treatments.

4. eosungcho pharmacology,

Whole liquid (煎 液) has excellent diuretic effect by potassium salt and quercitrin, antifungal action and antibacterial activity against ringworm.

The application of the medicine,

It is used to clear the lungs, and is used for blood clotting, detoxification, swelling, poisoning, and pulmonary bleeding.

5. Mistletoe will live on the willow, weeping willow, and maple trees, and the medicine is used for the above life and mistletoe, and the above life is mulberry, camphor tree, cypress, jujube tree, longan It is parasitic on trees and mistletoes on elm, birch, willow, maple and pyrite.

The main component of mistletoe was oleanolic, and the main component of the above-mentioned raw material consisted of quercetin and abicurin.

Pharmacology-The inhibitory effect of the hot-water leachate on the white mucus meat was 39.5%, and the inhibition rate of the hot-water leachate on the white mucus meat was 77.9%.

The description of the above life in the main chojinjin (상기 生) said that said life is a new blood urea (보 要 制),

Healing, nurturing, subcutaneous fracture, hard water, vigorous blood, stabilizing and analgesia. I introduce it.

6. Confectionery

As a year-round herb of the fruit family, the "sweets remove the freckles of the skin and make the skin smooth." Daemyung Ilhwa has been reviewed in Boncho, and in the Herb Garden, It is effective in controlling the urinary tract of the heart, the elimination of intestinal injection, the control of the intestines, and the treatment of carbuncles in the stomach. It is written.

Confectionery contains saponin, fatty oil, urea, and a small amount of adenine and trigonelline.

7. Blind Root

Mainly using the root, Jinhae, expectoration, healthy, hematopoietic effect.

8. Pipa

It mainly uses leaves and contains amigdalin (AMYGDALIN), asolic acid (ARSOLICACID), oleanolic acid (OLEANOLICACID) and maslinic acid (MASLINICACLD).

9. Syringe

Used as a painkiller, taste is very bitter and cold. Loosen the blood and pain.

There is an ingredient of aristolochia kaempferiwilld.

It has anticancer activity by the action of Aristolockki acid and promotes the function of the bacteriophage lamentation of white blood cells.

10. Overweight

The overweight is dried dried melon faucet and contains cucurbitacin A, B, C, D, and E. It is used for jaundice, edema, expectoration, etc.

Elm, Redwood, Estuary, Mistletoe, Copper, Seeds,

Loquats are washed separately, completely dried, and pulverized with a grinder to powder. Syringes and fruit bodies make up the extract extracted by hydrothermal leaching which is decanted from the hydrothermal inside the reactor. Among the above materials, powder material and loess are put in a stirrer and mixed by first stirring, followed by adding and stirring the syringe extract and excess extract to form a mixture and mixing until the water content of the mixture reaches 20%. It is dried and ground to a powder in a grinder to form a pharmaceutical composition.

The culture of slugs is sprayed with a certain thickness of the powder of the medicinal composition in the incubator formed inside the temperature controllable incubator, the slugs are implanted at a constant density on the powder, and the growth rate of the slugs is lowered. Incubate by keeping the internal temperature within the range of 5 to 10 ℃ and incubating the slugs while maintaining the temperature inside the incubator in the range of 5 to 6 ℃ in order to delay the pupal stage when the slugs are chrysalisified do. If the temperature of the culture medium during the slug culture is less than 5 ℃, slugs die or the culture is completely stopped, and if the temperature exceeds 10 ℃, the growth rate of slugs is too fast to pupate early. When the slugs are finished growing, each slug grows at a weight of 3-5 g. Since slugs are increased in the culture period in order to improve the anticancer effect, slugs are kept in the range of 5 to 6 ° C to delay the pupalization. Increase the incubation period of the species.

The chrysalis extract consists of a hydrothermal leaching method that runs for a certain period of time in hot water. The slugs are cultured by the medicinal composition in the hot water inside the reactor, and the heating is completed. When the leaching is completed, the heating is stopped and gradually cooled to remove the pupa extract. Configure.

Spread the powder of the medicinal composition to a incubator formed in the Ganoderma lucidum culture in a constant thickness, injecting Ganoderma lucidum mycelium into the powder and germinating to cultivate Ganoderma lucidum mushrooms and put the Ganoderma lucidum mushroom in the hot water inside the reactor for a certain time The Ganoderma lucidum extract is composed by the hydrothermal leaching method, and the pupa extract and the Ganoderma lucidum extract are mixed to form an anticancer health food.

Slugs cultivated for a long time at a constant temperature by applying a medicinal composition consisting of a number of natural medicinal herbs excellent in anti-cancer and related actions to maintain the toxicity of the medicinal herbs while maintaining the anticancer action of the natural medicinal herbs as it is Since it neutralizes or eliminates the side effects of the medicines when taking the slug extracts hydrothermally leached from the slugs. Reishi mushroom cultivated by injecting the Ganoderma lucidum mycelium into the medicinal composition also neutralizes or eliminates the toxicity of the medicinal herbs while maintaining the anticancer activity of the natural medicinal herbs, and also because the Ganoderma lucidum itself has excellent anticancer activity The hydrothermal leached extract from Ganoderma lucidum grown in the composition also has excellent anticancer activity and does not cause side effects in the human body.

Pharmacological action of natural herbs and loess and Ganoderma lucidum applied to the present invention is as follows.

As described above, the Koji mulberry extract has excellent cancer suppression and analgesic effects, and particularly, flavones contained in the tree have an excellent cytotoxic effect on cancer cells. Elm has the effect that the extract removes cancer cells and pus, and boost the flesh on the site where the cancer cells and pus is removed. Oak tree is also called arrowwood, the extract has anti-cancer effect, reduce diabetes, increase weight and promote blood circulation. Eoseongcho is also known as weak buckwheat and removes or diverges tumors or pus and has excellent diuretic effect. Mistletoe is parasitic on elm, birch and willow, and alkaline poisonous protein contained in mistletoe is excellent for inhibiting tumor cell growth. It is applied to the treatment of mammary and uterine cancer in foreign countries. It promotes blood circulation. Dong-Gwa is a seed of Dong-Gwa belonging to the gourd, which contains terpene compounds with excellent anti-cancer activity. It has excellent anti-cancer and diuretic effects and alleviates various symptoms caused by tumors. Losing weight The roots of blindness have the effect of treating detoxification and clearing and spasms to muscles and bones. Loquat has excellent anti-cancer activity and neutralizing effect on the toxicity of medicinal products. Aristorochy acid, which contains M. erysipelas, has anticancer activity. In particular, leukocytes promote the bacteriophage lamentation function. In addition, M. extracts have better analgesic activity than morphine. Overweight is the dry tap of melons, which is excellent for the treatment of jaundice.

As described above, each natural medicinal herb has an anticancer effect and a pharmacological effect on specific symptoms related thereto, while each drug has a toxic or side effect, and thus the entire medicinal herb is applied in a constant weight part. By forming a medicinal composition, the pharmacological action of the medicinal herb complements and neutralizes each toxicity or side effect. For example, copper seed powder has a side effect of reducing weight, while sesame tree powder has an effect of increasing weight, and thus, the composition of the medicinal composition is applied simultaneously with the copper seed powder and the true bark powder to form the body weight of the human body. Eliminate the side effects of reduction.

Ocher is a substrate for adsorbing a plurality of natural medicines in the medicinal composition to promote the growth of slugs and the growth of ganoderma lucidum mycelium and the growth of ganoderma lucidum mushrooms.

Ganoderma lucidum mushroom has excellent anti-cancer activity, and when the medicinal composition composed of the natural medicinal herb is cultivated as a host, the anti-cancer effect of Ganoderma lucidum is enhanced by the natural medicinal herb, while the toxicity of the medicinal herb is neutralized. Removed.

Example-1

1. Preparation of the ingredients of the herbal composition

Koji Mulberry is dried by washing leaves, stems and roots, and then pulverizing with a grinder to powder. Elm and true-beech trees, like Koji mulberry, are washed with leaves, stems, and roots, completely dried, and then pulverized with a grinder to be powdered. Eoseongcho, mistletoe, copper seed, persimmon root and loquat are washed separately, completely dried, and pulverized with a grinder to powder them. Syringes and overweight apply the hydrothermally leached extract, which is mixed with hot water in the reaction tank with 0.1 wt% of syringes and heated at 100 ° C for 2 hours. do. The extract of the excess is mixed with 0.5% by weight of the dried excess in hot water inside the reactor and heated at 100 ° C. for 2 hours, when the volume of the aqueous solution is reduced to 80%, and is gradually cooled and stored. Ocher is dried and powdered.

2. Composition of medicinal composition

10% by weight of Guji mulberry powder, 10% by weight of elm tree powder, 5% by weight of sesame tree powder, 5% by weight of eochocho powder, 5% by weight of mistletoe powder, 2% by weight of copper and seed powder and 6% of persimmon root powder %, 5% by weight of loquat powder and 45% by weight of loess were added to the stirrer and mixed by first stirring. Then, 3% by weight of the overextract extract and 4% by weight of the injection of the medicinal extract were mixed by stirring and mixed thoroughly. Consists of a medicinal composition of 20%.

3. Cultivation of slugs

By spraying the powder of the medicinal composition to a predetermined thickness in the incubator formed inside the temperature controllable culture medium to transplant slugs (larvae of cicada, scarab, stag beetle, mulberry moth) at a certain density on the powder and of the slugs In order to reduce the growth rate, the temperature inside the culture chamber is maintained within the range of 5 to 10 ° C., and the temperature inside the culture room is within the range of 5 to 6 ° C. in order to delay the chrysalisation rate when the slugs are chrysalisated. Incubate slugs while maintaining in As the incubation period of slugs increases, the weakness improves, but the larvae duration of the slugs is limited, so the larvae duration of slugs is limited from 36 months to 42 months to increase the larvae duration and increase the weakness of the slugs. Will be.

As described above, the environment of the inside of the culture medium is continuously maintained in the range of 5 to 6 ° C. so that the larvae of slugs do not become pupa for 36 to 42 months.

4. Composition of pupa extract

The chrysalis extract is composed of hydrothermal leaching method, which is incubated in the hot water inside the reactor by medicinal composition and adds 3% by weight compared to the slugs hot water, which is grown, and heated to 100 ° C. and the volume of the aqueous solution in the reactor is reduced to 20%. Stop heating and cool slowly to form chrysalis extracts.

5. Composition of Ganoderma lucidum Extract

10% by weight of Guji mulberry powder, 10% by weight of elm tree powder, 5% by weight of sesame seedling powder, 5% by weight of Echo herb powder, 5% by weight of mistletoe powder and 2% by weight of Cucumber powder %, 6% by weight persimmon root powder, 5% by weight loquat powder and 45% by weight loess were added to the stirrer and mixed by first stirring. Then, 3% by weight of the excess extract and 4% by weight of the lotus extract were added and agitated completely. Mixing and spraying the powder of the medicinal composition of which the moisture content of the composition is 20% to a constant thickness, and injecting the Ganoderma lucidum mycelium at a constant density and germination to cultivate Ganoderma lucidum.

Put the Ganoderma lucidum cultivated in the medicinal composition 6% by weight compared to the hot water and heated for a certain time, when the hot water is reduced by 20% compared to the hot water stops heating to form a ganoderma lucidum extract by the hydrothermal leaching method cooled at room temperature.

6. Composition and use of health food

50% by weight of the slug extract and 50% by weight of ganoderma lucidum extract. The mixture of the extract as described above is packed in a small amount so that it is taken in a heavy bath (重 진).

Anti-cancer health food according to the present invention by applying the medicinal composition consisting of various natural medicinal herbs and ocher excellent in anti-cancer action or various pharmacological effects accompanying it as a feed cultivated slugs and the extract of the slugs hydrothermally leached, Since the medicinal composition is composed by mixing the extract of the Ganoderma lucidum mycelium cultivated by injecting a hot water leaching extract of the Ganoderma lucidum mycelium, while the anticancer and related action of the medicinal composition is maintained while the toxicity contained in the medicinal herbs is neutralized and cultured Neutralizes or is eliminated by slugs and ganoderma lucidum, so anticancer and related actions are excellent and there are no side effects on the human body.

Claims (4)

10% by weight of Koji mulberry powder, 10% by weight of elm powder, 5% by weight of red oak tree powder, 5% by weight of vinegar powder, 5% by weight of mistletoe powder, 2% by weight of powdered copper seed and 2% by weight of persimmon root powder and loquat powder Slugs cultured by feeding the medicinal composition consisting of 5% by weight, 3% by weight of the extract of Gae melon and 4% by weight of the lotus extract and 45% by weight of ocher (larvae of cicada, scarab, stag beetle, mulberry moth) 50% by weight of the hydrolyzed slug extract, 10% by weight of Gujimi tree powder, 10% by weight of elm tree powder, 5% by weight of sesame tree powder, 5% by weight of Echo herb powder, 5% by weight of mistletoe powder and 2% by weight of copper and seed powder. Ganoderma lucidum cultivated by injecting Ganoderma lucidum mycelium into a medicinal composition consisting of 6% by weight of persimmon root powder, 6% by weight of loquat powder, 5% by weight of dongdong melon extract, 4% by weight of lotus leaf extract and 45% by weight of ocher The anti-cancer health food for being configured to mix the hot water was leaching Ganoderma lucidum extract 50% by weight. The anti-cancer health food according to claim 1, wherein the temperature for incubating slugs is in the range of 5 to 6 ° C. and the culture period is 36 months to 42 months. The anti-cancer health food according to claim 1, wherein the moisture content of the composition for raising slugs is 20%. The anti-cancer health food according to claim 1, wherein the moisture content of the composition for growing Ganoderma lucidum is 35%.