CN112043730A - Traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases - Google Patents
Traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases Download PDFInfo
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Abstract
A Chinese medicinal biological preparation for preventing and treating animal epidemic disease is prepared by extracting Chinese medicinal materials to obtain Chinese medicinal liquid, using the Chinese medicinal liquid as liquid culture medium, inoculating Pleurotus ostreatus strain, performing liquid submerged culture, allowing the liquid culture medium to overgrow with bacteria balls to obtain Chinese medicinal liquid strain, inoculating biological strain, and continuously culturing to obtain biological bacterial liquid; drying and crushing the traditional Chinese medicine residues after the traditional Chinese medicine juice is obtained, then mixing with auxiliary materials, sterilizing, inoculating with a ganoderma lucidum strain, then cultivating until the traditional Chinese medicine residues overgrow with ganoderma lucidum mycelia to obtain a ganoderma lucidum traditional Chinese medicine complex, and finally adsorbing biological bacteria liquid by using the ganoderma lucidum traditional Chinese medicine complex for secondary fermentation to obtain the traditional Chinese medicine biological preparation which has the functions of adjusting the basis, strengthening the basis, removing fire to nourish yin, purging fire to discharge cold, promoting blood circulation to remove blood to nourish blood and the like and has the obvious function of preventing and treating animal epidemic diseases.
Description
Technical Field
The invention belongs to the technical field of bioengineering technology and animal disease prevention and control, and particularly relates to a traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases.
Background
Animal epidemic disease refers to animal infectious disease and parasitic disease.
The Swine fever-caused disease is serious in harm to human and animals, needs urgent and strict measures such as forced prevention, control and extinguishment, for example, the epidemic diseases of the African Swine fever which is prevalent in the years belong to epidemic diseases, and the African Swine fever (African Swine farm, East African Swine farm, ASF) is a Swine disease caused by acute and infectious filterable viruses with high fever and infectivity, and is characterized in that the disease process is short, but the death rate is up to 100%. Because no vaccine capable of effectively preventing the African swine fever is developed worldwide, the biological safety protection of the farm is the key for preventing and controlling the African swine fever.
May cause great economic loss, needs to take strict control, extinction and other measures to prevent the spread of the disease. Such as rabies, brucellosis, anthrax, pseudorabies, clostridium welchii disease, paratuberculosis, toxoplasmosis, echinococcosis, leptospirosis, and the like.
The diseases are frequently encountered, can cause great economic loss, and need to be controlled and purified, namely three kinds of epidemic diseases. Such as colibacillosis, listeriosis, melioidosis, actinomycosis, fascioliasis, filariasis, eperythrozoonosis, Q fever, etc.
Currently, the nation carries out a major precaution policy for animal epidemic diseases.
After the feed is prohibited to resist, the morbidity and mortality of animals are obviously increased, and if antibiotics are added to the feed for health care in a private farm, the feed is not only small in amount but also cannot be mixed uniformly, and serious side effects are caused by large-dose application.
Enterprises and research and development organizations are encouraged to accelerate the development of antibiotic substitute products such as biological feed, enzyme preparations, probiotics, plant extracts and the like all the time after the resistance is forbidden in the rural part of agriculture, the decrement substitution of antibiotics in the whole industry is promoted, and the quality safety of livestock and poultry products is ensured.
At present, Chinese herbal medicines are utilized to adjust the basis to consolidate the basis (spleen and stomach are adjusted to consolidate liver and kidney, but pure tonification is easy to lead stagnation), remove fire to nourish yin (fire excess must have fire deficiency, fire should not be easily discharged), discharge fire to discharge cold (cold hurts heart, heart and spleen deficiency), promote blood circulation to circulate blood to nourish blood, dredge qi movement to invigorate qi and other action mechanisms, and Chinese herbal medicine formula research and development are carried out to treat and prevent various animal epidemic diseases through the traditional Chinese medicine syndrome differentiation of animal epidemic diseases, so that good effects are obtained. Especially, the Chinese herbal medicine has obvious advantages in the aspects of clearing away heat and toxic materials, regulating immunity, resisting viruses, improving vaccine titer, resisting stress and the like.
Disclosure of Invention
The invention aims to provide a brand-new traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases. The method specifically comprises the following steps: the preparation is prepared by using honeysuckle, weeping forsythia, common andrographis herb, indigowoad leaf, indigowoad root, natural indigo, cyrtomium rhizome, dandelion, Chinese violet, wild chrysanthemum flower, Indian buead, liquoric root, golden thread and cordyceps militaris as raw materials, extracting the raw materials of the traditional Chinese medicines to obtain a traditional Chinese medicine liquid, using the traditional Chinese medicine liquid as a liquid culture medium, then inoculating pleurotus ostreatus strains, enabling the liquid culture medium to overgrow with fungus balls after liquid submerged culture to obtain a traditional Chinese medicine liquid strain, inoculating the traditional Chinese medicine liquid strain into a biological strain, and continuously culturing to obtain a biological bacterium liquid; drying and crushing the traditional Chinese medicine residues after the traditional Chinese medicine juice is obtained by extraction, then mixing with auxiliary materials, sterilizing, inoculating with a ganoderma lucidum strain, then culturing until the traditional Chinese medicine residues overgrow with ganoderma lucidum mycelia to obtain a ganoderma lucidum traditional Chinese medicine complex, and finally adsorbing biological bacteria liquid by using the ganoderma lucidum traditional Chinese medicine complex for secondary fermentation to obtain the traditional Chinese medicine biological preparation capable of effectively preventing and treating animal epidemic diseases.
The invention is realized by the following technical scheme:
1. a traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases adopts the technical scheme that: the preparation is prepared by using honeysuckle, weeping forsythia, common andrographis herb, indigowoad leaf, indigowoad root, natural indigo, cyrtomium rhizome, dandelion, Chinese violet, wild chrysanthemum flower, Indian buead, liquoric root, golden thread and cordyceps militaris as raw materials, extracting the raw materials of the traditional Chinese medicines to obtain a traditional Chinese medicine liquid, using the traditional Chinese medicine liquid as a liquid culture medium, then inoculating pleurotus ostreatus strains, enabling the liquid culture medium to overgrow with fungus balls after liquid submerged culture to obtain a traditional Chinese medicine liquid strain, inoculating the traditional Chinese medicine liquid strain into a biological strain, and continuously culturing to obtain a biological bacterium liquid; drying and crushing the traditional Chinese medicine residues after the traditional Chinese medicine juice is obtained by extraction, then mixing with auxiliary materials, sterilizing, inoculating with a ganoderma lucidum strain, then culturing until the traditional Chinese medicine residues overgrow with ganoderma lucidum mycelia to obtain a ganoderma lucidum traditional Chinese medicine complex, and finally adsorbing biological bacteria liquid by using the ganoderma lucidum traditional Chinese medicine complex for secondary fermentation to obtain the traditional Chinese medicine biological preparation capable of effectively preventing and treating animal epidemic diseases.
2. A traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases adopts the technical scheme that the traditional Chinese medicine comprises the following components in parts by weight: 10-18 parts of honeysuckle, 10-15 parts of fructus forsythiae, 12-20 parts of common andrographis herb, 8-12 parts of folium isatidis, 8-10 parts of isatis root, 3-6 parts of indigo naturalis, 3-5 parts of cyrtomium rhizome, 2-4 parts of dandelion, 2-3 parts of Chinese violet, 5-8 parts of wild chrysanthemum flower, 6-10 parts of poria cocos, 4-6 parts of licorice leaves, 4-6 parts of coptis chinensis and 5-8 parts of cordyceps militaris.
3. A traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases is characterized in that the extraction method of traditional Chinese medicine juice is as follows:
(1) raw material treatment: mixing the above Chinese medicinal materials, and pulverizing into powder capable of passing through 20-30 mesh sieve;
(2) and (3) extraction: according to the proportion of putting 5-10 kg of the crushed traditional Chinese medicine in 100 kg of water, putting the crushed traditional Chinese medicine and the water in a heating container together, then heating until the water is boiled, continuously heating until the water in the container is reduced by half, and finally filtering to obtain the traditional Chinese medicine juice.
4. A Chinese medicinal biological preparation for preventing and treating animal epidemic diseases, which adopts the technical scheme that the cultivation method of Chinese medicinal liquid strains comprises the following steps:
(1) collecting strains: collecting Pleurotus species commonly used in the field as a bacterial source;
(2) preparing test tube species: 200 g of potato, 10 g of glucose, 20 g of agar, 500 ml of the traditional Chinese medicine juice and 500 ml of clear water, peeling the potato, cutting the potato into small pieces, putting the potato, the traditional Chinese medicine juice and the clear water into a heating container, heating until the water boils, adding the glucose and the agar, subpackaging the mixture into test tubes, sterilizing the test tubes to prepare inclined test tubes, and inoculating pleurotus strains into the inclined test tubes to cultivate the pleurotus strains to obtain test tube seeds;
(3) preparing a first-stage liquid strain: peeling potato 200 g, white sugar 10 g, peptone 5g, the Chinese medicinal juice 800 ml and water 200 ml, cutting the peeled potato into small pieces, placing the potato, the Chinese medicinal juice and clear water into a heating container, heating until the water is boiled, adding the white sugar and the peptone into a nutrient solution, subpackaging the nutrient solution into triangular flasks, and finally sterilizing, inoculating test tube seeds and culturing to obtain a primary liquid strain;
(4) preparing traditional Chinese medicine liquid strains: 100000 ml of the traditional Chinese medicine juice, 2000 g of brown sugar and 500 g of peptone, putting the traditional Chinese medicine juice, the brown sugar and the peptone into a fermentation tank, then sterilizing according to a conventional method, then inoculating a first-level liquid strain, and finally culturing to obtain a traditional Chinese medicine liquid strain.
5. A Chinese medicine for preventing and treating epidemic diseases of animal is prepared from the bacterial liquid through culturing
(1) Collecting biological strains: collecting beneficial biological strains with effective viable count of more than or equal to 5 multiplied by 100/ml as a bacterial source;
(2) fermentation: 100000 ml of traditional Chinese medicine liquid strain, 5000 g of brown sugar and 2000 ml of biological strain, putting the brown sugar and the traditional Chinese medicine liquid strain into a fermentation container, stirring until the brown sugar is completely dissolved in the traditional Chinese medicine liquid strain, and putting the biological strain into the traditional Chinese medicine liquid strain for anaerobic fermentation for 6-10 days to obtain biological bacteria liquid.
6. A Chinese medicinal biological preparation for preventing and treating animal epidemic diseases is prepared by culturing Ganoderma lucidum Chinese medicinal complex:
(1) collecting ganoderma lucidum strains: collecting ganoderma lucidum strains commonly used in the field as a strain source;
(2) principle processing: drying the traditional Chinese medicine residue after the traditional Chinese medicine juice is obtained by extraction until the water content of the materials is lower than 20 percent for later use;
(3) the raw materials comprise the following components in percentage by weight: 70 parts of traditional Chinese medicine residues, 20 parts of bran and 10 parts of corn flour, and mixing the traditional Chinese medicine residues, the bran and the corn flour and uniformly stirring to obtain a mixed culture material;
(4) culturing ganoderma lucidum mycelia: adding appropriate amount of clear water into the mixed culture medium to make the water content of the mixed culture medium reach 55-60%, subpackaging in culture container, sterilizing according to conventional method, inoculating Ganoderma strain in sterile environment, and culturing until the mixed culture medium is full of Ganoderma mycelia to obtain Ganoderma traditional Chinese medicine complex.
7. A traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases adopts the technical scheme that the preparation method of the traditional Chinese medicine biological preparation comprises the following steps:
(1) mixing raw materials: mixing Ganoderma traditional Chinese medicine complex and biological bacterial liquid, and stirring to make water content of the mixture reach 55-60%;
(2) fermentation: placing the mixed material in a clean fermentation chamber for semi-itching fermentation until white hypha is fully developed on the surface of the mixed material, and then completing fermentation;
(3) and (3) finished product: and drying the fermented mixed material at 50 ℃ until the water content of the material is lower than 8% to obtain the finished product of the traditional Chinese medicine biological preparation.
The flos Lonicerae is a dry flower bud of Caprifoliaceae plant, belongs to a sweet and cold-natured plant, and belongs to lung, heart and stomach channels, has effects of clearing heat and detoxicating, and dispelling pathogenic wind and heat, and can be used for treating swelling and pain, erysipelas, common cold, warm disease, etc. It is called as traditional Chinese medicine antibiotic, is similar to dandelion, has wide resource distribution and more chemical components and functions in our country, and is widely used in the industries of food, cosmetics, some health care products and the like besides the medicine. Researches show that the honeysuckle extract and some chemical components contained in the honeysuckle extract have various pharmacological effects, mainly comprise anti-inflammatory, antibacterial, antiviral, antioxidant and the like according to the structure, and have certain effects on tumor prevention due to the anti-inflammatory and antibacterial effects. Honeysuckle tea is available in the market at present, and can be drunk frequently.
The forsythia has broad-spectrum antibacterial effect, has strong inhibiting effect on staphylococcus aureus and shigella dysenteriae, and has certain inhibiting effect on other pathogenic bacteria, influenza virus and fungi. Has anti-inflammatory effect. Oleanolic acid contained in fructus forsythiae has effects of tonifying heart, promoting urination and lowering blood pressure, and vitamin P can reduce vascular permeability and fragility, and prevent hemolysis. The decoction has effects of relieving vomiting and resisting liver injury. Clearing away heat and toxic material, dispersing swelling and dissipating stagnation, and dispelling wind-heat. It is mainly used for treating carbuncle, swelling, sore, subcutaneous nodule, scrofula, wind-heat type affection, early stage of epidemic febrile disease, stranguria with heat, and pain.
The herba Andrographitis has bitter and cold taste, and has effects of clearing heat and detoxicating, resisting blood platelet aggregation, improving blood viscosity, cooling blood and detumescence, protecting liver and promoting bile flow.
The dyers woad leaf belongs to heat-clearing and detoxifying medicines in traditional Chinese medicines, is bitter and cold in nature, enters liver, heart, stomach and spleen meridians, and has the effects of clearing heat and detoxifying, cooling blood and removing ecchymoses. The traditional Chinese medicine is mainly used for treating diseases such as heat toxin, erysipelas, sore throat, aphtha of the mouth and tongue, sore and carbuncle and pyogenic infections in the traditional Chinese medicine clinic.
The isatis root is bitter in taste and cold in nature, enters heart and stomach meridians, has the effects of clearing heat and removing toxicity, cooling blood and relieving sore throat, and is mainly used for treating warm diseases, fever, headache and throat pain or various syndromes of exuberance of heat toxin such as warm toxicity and macula, mumps, carbuncle, sore toxin, erysipelas, fever with big head and the like. It has the actions of clearing heat, removing toxicity and cooling blood, and is mainly indicated for removing toxicity, relieving sore throat and dissipating nodulation. It can be used for treating diseases due to toxic heat, such as influenza, upper airway inflammation, epidemic cerebrospinal meningitis, parotitis, acute enteritis, and bacillary dysentery. Pharmacological research shows that the isatis root has obvious inhibition effect on various viruses and germs.
The natural indigo is a cool nature Chinese medicine, has good effects of clearing liver-fire, clearing heat and detoxicating, and can also be used for arresting convulsion. Has certain curative effect on parotitis, infantile convulsion, erysipelas, cough due to lung heat and other diseases.
The rhizoma Osmundae can clear away heat and toxic materials, and treat wind-heat type common cold; can also stop bleeding, and can be used for hematemesis, hematochezia or metrorrhagia and metrostaxis; it can also be used for treating metrorrhagia, damp-heat swelling and pain. Can be used for treating parotitis and enterobiasis, and preventing influenza and Japanese encephalitis.
The dandelion is bitter and sweet in taste and cold in nature, belongs to liver and stomach meridians, and has the effects of clearing away heat and toxic materials, eliminating carbuncles, dissipating stagnation, promoting diuresis and treating stranguria. Clinically, dandelion is used for treating carbuncle, furunculosis and acute mastitis. Dandelion is bitter in flavor to purge and descend, sweet in flavor to remove toxicity, cold in property to clear heat, resolve hardness and dissipate stagnation of qi, and is a good product for clearing heat, removing toxicity, curing abscess and dissipating stagnation. Mainly treats the symptoms of internal and external heat toxin and sore and carbuncle, and the dandelion has the functions of stimulating the menstrual flow and promoting lactation, and is a good medicine for treating acute mastitis. In addition, dandelion can be used for treating painful and astringent stranguria due to heat, jaundice due to damp-heat and conjunctival congestion and swelling and pain caused by flaming up of liver fire, and has the effects of clearing liver and improving vision.
The Chinese violet is a very good medicine for clearing heat and removing toxicity, cooling blood and eliminating carbuncle. It is clinically used to treat the symptoms of upper energizer fire-heat, such as swollen and sore throat and aphthous stomatitis. Because the herba violae can be used together with other heat-clearing and detoxifying drugs to treat furuncle.
The wild chrysanthemum is a common traditional Chinese medicine in the aspect of traditional Chinese medicine, and has the effects of clearing heat, reducing internal heat, removing liver fire, improving eyesight, resisting bacteria, diminishing inflammation and detoxifying.
The poria cocos belongs to a medicine for inducing diuresis to alleviate edema and has the effects of inducing diuresis to eliminate dampness, tonifying spleen and calming heart. The traditional Chinese medicine composition is clinically applied to edema, phlegm and fluid retention diseases caused by various reasons, poor appetite caused by spleen deficiency, palpitation caused by heart-spleen deficiency, insomnia caused by severe palpitation and the like.
The liquorice has the effects of tonifying middle-jiao and Qi, relieving spasm and pain, clearing heat and removing toxicity, eliminating phlegm and stopping cough and harmonizing drug property, belongs to qi tonifying medicines in traditional Chinese medicines, and has a good qi tonifying effect, particularly a good effect of tonifying heart-qi. Licorice root, radix Glycyrrhizae can relieve spasm and pain, and can be used for treating abdominal pain, spasm and pain of limbs due to deficiency-cold of spleen and stomach or deficiency of yin and blood. The actions of Licorice root in clearing heat and removing toxicity are mainly reflected in treating sore throat, skin sore and ulcer, etc. caused by heat-toxin invasion.
The coptis chinensis is mainly used for treating diseases such as damp-warm, vomiting, diarrhea, excessive heat-toxin and fire, headache and conjunctival congestion, mouth and tongue sores, vexation and insomnia, upward invasion of heat-toxin and the like. Has the effects of purging fire, removing toxic substances, clearing heat and eliminating dampness. Also has antibacterial, blood sugar lowering, and malaria treating effects. Can also treat digestive tract inflammation, so the medicinal value is very high and the effect is very good. After the coptis chinensis is used, the main component berberine of the coptis chinensis cannot enter blood through gastrointestinal mucosa, the berberine mainly stays in the gastrointestinal tract, the residence time of the berberine in the gastrointestinal tract is prolonged due to the bitter and astringent effect, and the treatment effect on the digestive inflammation is very obvious.
The cordyceps militaris, also called as cordyceps militaris, is an edible fungus rich in nutrients such as cordycepin, cordycepic acid, cordyceps polysaccharide, high protein, amino acid and the like, and is a superior nourishing product. At present, the artificially cultivated cordyceps militaris mainly comprises two types: one is that the cordyceps strains are inoculated into the silkworm pupa which is artificially bred and cultivated to grow a silkworm pupa cordyceps character base, the second is the most common cordyceps flower in the market, and the cordyceps strains are inoculated into cereals, wheat and the like and cultured to obtain cordyceps fruiting bodies. The cordyceps militaris and the cordyceps sinensis belong to the genus cordyceps of the phylum mycomycota, and have similar medicinal and nourishing effects, and a large number of scientific researches prove that the edible and medicinal values of the cordyceps militaris can be comparable with those of the traditional cordyceps sinensis, and the cordycepin content in the artificially cultured cordyceps militaris is dozens of times higher than that of the traditional cordyceps sinensis. Has effects in nourishing lung, invigorating kidney, stopping bleeding, eliminating phlegm, dilating trachea, tranquilizing mind, resisting bacteria, and lowering blood pressure. The research and detection of various countries in the world prove that the cordyceps militaris is the most ideal substitute of the traditional cordyceps militaris.
The pleurotus ostreatus, an edible fungus widely occurring in autumn, winter and spring on dead stems of broad-leaved trees, is one of the main artificial cultivation edible fungi in the world, and belongs to the pleurotus ostreatus (tricholoma giganteum) family. The pleurotus ostreatus is rich in nutrition, and each 100g of dried pleurotus ostreatus contains 19.5g of crude protein (containing 11 g of pure protein), 3.8g of crude fat, 50.2g of carbohydrate, 6.2g of crude fiber, mineral elements such as calcium, phosphorus and iron, vitamin B1, vitamin B2, vitamin C, provitamin D and the like. The pleurotus contains 8 kinds of amino acids essential to the human body, i.e., isoleucine, leucine, tryptophan, phenylalanine, threonine, valine, methionine, etc. In addition, the beverage is rich in vitamin B1, vitamin B2, vitamin PP, oxalic acid and the like. Anticancer experiment shows that the water extracted liquid of sporophore has 75% inhibition rate on mouse sarcoma 180 and 60% inhibition rate on Ehrlich carcinoma. Can be used as Chinese medicine for treating soreness of waist and legs, numbness of limbs, and discomfort of tendons and collaterals. The strain can be cultured by submerged fermentation with mycelium in addition to large amount of artificial cultured sporophore.
The lucid ganoderma is a treasure in Chinese medical treasury and is really reputed to be 'immortal grass'. Both ancient and modern pharmacological and clinical researches prove that the ganoderma lucidum indeed has the effects of preventing and treating diseases and prolonging life. The "Shennong Ben Cao Jing" in eastern Han and the "Ben Cao gang mu" in Li Shizhen, a famous medical specialist in the Ming dynasty both have detailed and very definite records on the efficacy of Ganoderma lucidum. Modern pharmacology and clinical practice further prove the pharmacological action of ganoderma lucidum, and prove that ganoderma lucidum polysaccharide is a main component of ganoderma lucidum for strengthening body resistance, consolidating the constitution, nourishing, strengthening and prolonging life. At present, the ganoderma lucidum is officially collected and carried by the national formulary as a medicine, is a new resource food approved by the state, has no toxic or side effect, and can be used as both medicine and food. Scientific research shows that the pharmacological components of ganoderma are very rich, wherein the effective components can be divided into ten major categories, including ganoderma lucidum polysaccharide, ganoderma lucidum polypeptide, triterpenes, 16 amino acids (including seven essential amino acids for human bodies), proteins, steroids, mannitol, coumarins, alkaloids, organic acids (mainly including fumaric acid), and trace elements of Ge, P, Fe, Ca, Mn, Zn and the like. The ganoderma lucidum has a bidirectional regulating effect on a human body, treats diseases, relates to various systems of cardiovascular and cerebrovascular diseases, digestion, nerves, endocrine, respiration, movement and the like, and particularly has very obvious effects of preventing and treating tumors, liver pathological changes, insomnia and aging.
The invention has the following advantages:
1. the preparation method of the traditional Chinese medicine biological preparation for preventing and treating the animal epidemic diseases has novel conception, simple production process and easy implementation.
2. By implementing the invention, the traditional Chinese medicine biological preparation contains high-grade edible and medicinal fungi such as cordyceps militaris, lucid ganoderma, pleurotus edible fungi and the like. Wherein, various Chinese herbal medicines in the components are used as culture mediums, and the ganoderma lucidum or oyster mushroom strains are used as a mushroom source to culture a derivative, namely mycelium, with the functions of the ganoderma lucidum or oyster mushroom, and the mycelium can be used as an effective component for regulating animals to consolidate the constitution and enhance the immunity, and the formed ganoderma lucidum and oyster mushroom derivative products have very low cost. The Chinese herbal medicine components in the biological preparation are reasonably combined, supplemented and complemented under the multiple fermentation action of the ganoderma lucidum strains, the pleurotus strains and the beneficial biological strains, so that the traditional Chinese medicine biological preparation which has the functions of strengthening the foundation, removing fire to nourish yin, purging fire to purge cold, promoting blood circulation to remove blood, dredging qi activity to replenish qi and the like and has the obvious function of preventing and treating the animal epidemic diseases is formed.
3. By implementing the invention, beneficial biological strains in the traditional Chinese medicine biological preparation can maintain the health of animal intestinal mucosa, promote the quick improvement of sub-health animal groups, improve the absorption of nutrient substances by livestock and poultry, and improve the daily gain in contrast; the metabolites of the beneficial biological bacteria can quickly make up the deficiency of endogenous enzymes in the digestive tract, maintain the microecological balance of the intestinal tract, reduce the burden of the intestinal tract, facilitate the absorption of nutrition and prevent the occurrence of the nutritional intestinal health problems of livestock and poultry; the beneficial biological bacteria can also improve the absorption of calcium, phosphorus, iron and other elements and organic trace elements, increase the ovulation quantity of livestock and poultry, and improve the farrowing (egg laying) quantity of the livestock and poultry; the beneficial biological bacteria can improve the digestion utilization rate of the feed, promote the decomposition of carbohydrates in the feed, promote the conversion of non-protein ammonia in the feed into high-quality protein, improve the utilization rate of the feed, improve the weight gain and reduce the feed conversion ratio; beneficial biological bacteria can also effectively improve the lean meat percentage, reduce the thickness of backfat, enable gluteus muscles and leg muscles to be plump and developed, have plump and firm bodies, improve the quality and the flavor of ketone bodies and improve the slaughter lean meat percentage; more importantly, the beneficial biological bacteria can also improve the culture environment and quickly reduce the odor and ammonia gas of the culture environment; the excretion of the animal excrement is reduced, the excrement is naturally formed, the water content of the excrement is reduced, and the natural fermentation speed of the animal excrement is accelerated.
4. By implementing the invention, Chinese herbal medicines in the traditional Chinese medicine biological preparation can be converted into micromolecular substances after being fermented by beneficial biological bacteria, thereby obtaining a means of nutrient stock solution which is convenient to be absorbed by organisms. In addition, the traditional Chinese medicine also has the following advantages after fermentation:
(1) the fermentation increases the content of functional components in the traditional Chinese medicine: fermentation of traditional Chinese medicine is a process of metabolism by microorganisms, and in the metabolism of microorganisms, some metabolites are produced; these metabolites can play a positive role in the body; for example, enzymes produced by microbial metabolism can promote extraction of effective components in cell walls of traditional Chinese medicines, thereby increasing the content of functional components in the traditional Chinese medicines; the fermentation can also promote the metabolism of cell protein in the traditional Chinese medicine, thereby improving the content of high-quality protein in the product; the microorganisms promote the release of functional components in the Chinese herbal medicine while metabolizing, thereby improving the efficacy of the Chinese herbal medicine; compared with traditional Chinese medicines, the fermented traditional Chinese medicine is more advanced in process and higher in absorption and utilization rate.
(2) The fermentation improves the drug effect of the traditional Chinese medicine: the traditional Chinese medicine is fermented to convert the components in the traditional Chinese medicine into small molecular substances, and the small molecular substances entering the body can be quickly absorbed and utilized by the body, so that the digestion pressure of intestines and stomach can be greatly reduced, the utilization rate of the body on the traditional Chinese medicine can be improved, and the efficacy of the traditional Chinese medicine is improved.
(3) The traditional Chinese medicine fermentation has smaller toxic and side effects than the traditional ferment: the Chinese medicines are three-way toxic, and not all the Chinese medicines can be used independently, some Chinese medicines are easy to cause body poisoning after being taken excessively, and the Chinese medicines can convert part of toxic substances in the Chinese medicines into small molecular substances of other components through fermentation, so that the toxin of the Chinese medicines is reduced. And after the traditional Chinese medicine is fermented, a proper amount of preparation is added to improve the taste of the traditional Chinese medicine, so that the traditional Chinese medicine is more easily accepted by people.
(4) Other active ingredients can be generated in the fermentation process of the traditional Chinese medicine: some substances obtained by metabolism in the microbial fermentation process belong to active ingredients, and the traditional Chinese medicine and the active ingredients mutually help to carry out various chemical reactions and generate new functional ingredients, so that the effect and the effectiveness of the traditional Chinese medicine are improved.
(5) The utilization rate of traditional Chinese medicine fermentation is higher than that of traditional Chinese medicines, and the environment can be protected to a certain extent: most of traditional Chinese medicines are processed in a cooking or soaking mode, so that functional components and nutritional values of the traditional Chinese medicines cannot be completely extracted, and the traditional Chinese medicine residues are not easy to degrade and easily cause environmental pollution. Most of the functional components of the fermented traditional Chinese medicine can be extracted, so that the resources can be efficiently saved, and most of the components of the fermented traditional Chinese medicine can be degraded in the fermentation process, so that the traditional Chinese medicine fermentation can also protect the environment to a certain extent.
(6) Traditional Chinese medicine fermentation is the manifestation of modernization of traditional Chinese medicines and is the combination of traditional Chinese medicines and technological innovation: traditional Chinese medicine fermentation is a very strict process, a scientific formula and a reliable fermentation process are required, and the traditional Chinese medicine fermentation is a chemical controllable process of an uncontrollable traditional Chinese medicine processing process, which is the expression of modernization of traditional Chinese medicines.
6. By implementing the invention, the prepared traditional Chinese medicine biological preparation not only has the characteristics and the effect of probiotics, but also contains a large amount of nutrient substances such as protein, saccharides, vitamins, amino acid and the like and active substances such as alkaloid, polysaccharide and the like, and has certain pharmacological effect; the Chinese medicinal biological preparation also has the characteristics of safety, green and the like, so the Chinese medicinal biological preparation is deeply favored by people, and has very great development prospect.
Detailed Description
The process of the present invention is further illustrated below with reference to examples.
A traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases adopts the technical scheme that: the preparation is prepared by using honeysuckle, weeping forsythia, common andrographis herb, indigowoad leaf, indigowoad root, natural indigo, cyrtomium rhizome, dandelion, Chinese violet, wild chrysanthemum flower, Indian buead, liquoric root, golden thread and cordyceps militaris as raw materials, extracting the raw materials of the traditional Chinese medicines to obtain a traditional Chinese medicine liquid, using the traditional Chinese medicine liquid as a liquid culture medium, then inoculating pleurotus ostreatus strains, enabling the liquid culture medium to overgrow with fungus balls after liquid submerged culture to obtain a traditional Chinese medicine liquid strain, inoculating the traditional Chinese medicine liquid strain into a biological strain, and continuously culturing to obtain a biological bacterium liquid; drying and crushing the traditional Chinese medicine residues after the traditional Chinese medicine juice is obtained by extraction, then mixing with auxiliary materials, sterilizing, inoculating with a ganoderma lucidum strain, then culturing until the traditional Chinese medicine residues overgrow with ganoderma lucidum mycelia to obtain a ganoderma lucidum traditional Chinese medicine complex, and finally adsorbing biological bacteria liquid by using the ganoderma lucidum traditional Chinese medicine complex for secondary fermentation to obtain the traditional Chinese medicine biological preparation capable of effectively preventing and treating animal epidemic diseases.
The specific implementation mode is as follows:
1. the traditional Chinese medicine comprises the following components in percentage by weight: 15 parts of honeysuckle, 12 parts of fructus forsythiae, 16 parts of common andrographis herb, 10 parts of folium isatidis, 9 parts of radix isatidis, 5 parts of indigo naturalis, 4 parts of cyrtomium rhizome, 3 parts of dandelion, 3 parts of Chinese violet, 6 parts of wild chrysanthemum flower, 8 parts of poria cocos, 5 parts of licorice leaves, 5 parts of coptis chinensis and 6 parts of cordyceps militaris.
2. The extraction method of the traditional Chinese medicine juice comprises the following steps:
(1) raw material treatment: mixing the above Chinese medicinal materials, and pulverizing into powder capable of passing through 20-30 mesh sieve;
(2) and (3) extraction: according to the proportion of 100 kg of water to 10 kg of the crushed traditional Chinese medicine, the crushed traditional Chinese medicine and the water are placed in a heating container together, then the heating is carried out until the water is boiled, the heating is continued until the water in the container is reduced by half, and finally the traditional Chinese medicine juice is obtained by filtering.
3. The cultivation method of the traditional Chinese medicine liquid strain comprises the following steps:
(1) collecting strains: collecting oyster mushroom strains as a mushroom source;
(2) preparing test tube species: 200 g of potato, 10 g of glucose, 20 g of agar, 500 ml of the traditional Chinese medicine juice and 500 ml of clear water, peeling the potato, cutting the potato into small pieces, putting the potato, the traditional Chinese medicine juice and the clear water into a heating container, heating until the water boils, adding the glucose and the agar, subpackaging the mixture into test tubes, sterilizing the test tubes to prepare inclined test tubes, and inoculating oyster mushroom strains into the inclined test tubes to cultivate the test tubes;
(3) preparing a first-stage liquid strain: peeling potato 200 g, white sugar 10 g, peptone 5g, the Chinese medicinal juice 800 ml and water 200 ml, cutting the peeled potato into small pieces, placing the potato, the Chinese medicinal juice and clear water into a heating container, heating until the water is boiled, adding the white sugar and the peptone into a nutrient solution, subpackaging the nutrient solution into triangular flasks, and finally sterilizing, inoculating test tube seeds and culturing to obtain a primary liquid strain;
(4) preparing traditional Chinese medicine liquid strains: 100000 ml of the traditional Chinese medicine juice, 2000 g of brown sugar and 500 g of peptone, putting the traditional Chinese medicine juice, the brown sugar and the peptone into a fermentation tank, then sterilizing according to a conventional method, then inoculating a first-level liquid strain, and finally culturing to obtain a traditional Chinese medicine liquid strain.
4. The method for culturing the biological bacterial liquid comprises the following steps
(1) Collecting biological strains: collecting EM strain with effective viable count not less than 5 × 100/ml as bacterial source;
(2) fermentation: 100000 ml of traditional Chinese medicine liquid strain, 5000 g of brown sugar and 2000 ml of EM strain, putting the brown sugar and the traditional Chinese medicine liquid strain into a fermentation container, stirring until the brown sugar is completely dissolved in the traditional Chinese medicine liquid strain, and putting the biological strain into the traditional Chinese medicine liquid strain for anaerobic fermentation for 6-10 days to obtain biological bacteria liquid.
5. The cultivation method of the ganoderma lucidum traditional Chinese medicine complex comprises the following steps:
(1) collecting ganoderma lucidum strains: collecting black ganoderma strains as a strain source;
(2) principle processing: drying the traditional Chinese medicine residue after the traditional Chinese medicine juice is obtained by extraction until the water content of the materials is lower than 20 percent for later use;
(3) the raw materials comprise the following components in percentage by weight: 70 parts of traditional Chinese medicine residues, 20 parts of bran and 10 parts of corn flour, and mixing the traditional Chinese medicine residues, the bran and the corn flour and uniformly stirring to obtain a mixed culture material;
(4) culturing ganoderma lucidum mycelia: adding appropriate amount of clear water into the mixed culture medium to make the water content of the mixed culture medium reach 55-60%, subpackaging in culture container, sterilizing according to conventional method, inoculating Ganoderma strain in sterile environment, and culturing until the mixed culture medium is full of Ganoderma mycelia to obtain Ganoderma traditional Chinese medicine complex.
6. The preparation method of the traditional Chinese medicine biological preparation comprises the following steps:
(1) mixing raw materials: mixing Ganoderma traditional Chinese medicine complex and biological bacterial liquid, and stirring to make water content of the mixture reach 55-60%;
(2) fermentation: placing the mixed material in a clean fermentation chamber for semi-itching fermentation until white hypha is fully developed on the surface of the mixed material, and then completing fermentation;
(3) and (3) finished product: and drying the fermented mixed material at 50 ℃ until the water content of the material is lower than 8% to obtain the finished product of the traditional Chinese medicine biological preparation.
Application example of the traditional Chinese medicine biological preparation (African swine fever epidemic prevention):
because the sweat glands of the pigs are few, the pigs cannot discharge heat through perspiration, internal heat cannot be discharged, and most of the heat diseases are common; a small number of sweat glands are distributed among the hoofs and the prongs, and internal heat prefers cold-dampness and cold is generated below feet. The dense striae, difficult invasion of exogenous wind, difficult or non-permeable internal heat, frequent fever with blood heat, heat toxin, body fluid deficiency and high fever, weak qi and blood, visible endogenous wind; the skin is dense and thick, the subcutaneous fat is thick, the people are afraid of heat and dryness without fear of external cold, but the internal heat and the internal dryness are averted to cold, and the people are averted to drink and dampness, and the internal cold syndrome is frequent, and the deficiency of the spleen and stomach is caused by deficiency of liver yin, namely the acquired deficiency (sweet food and eating are good for tonifying the spleen and stomach), the spleen is not transporting dampness, the damp turbidity is internally stopped and endogenous, the essence is not transformed, the qi and the blood are not generated, and the origin of all diseases is provided; pregnant sows suffer from dryness-heat and vexation in perinatal period, mostly accumulate cold in the interior, and the fetuses struggle for qi and blood deficiency; the diseases of both the mother and the son, as well as the gastrointestinal weakness of the piglet (sucking pig), the frequent occurrence of the digestive tract diseases of the piglet, etc. The prevention and control of the African swine fever are strict biological safety measures, and all virus sources which can enter a pig farm must be thought, so that the African swine fever is truly rejected. Secondly, according to the prevention theory of the traditional Chinese medicine that the vital qi exists in the interior, the pathogenic factors cannot be dried, and the qi is weakened, the natural disease resistance of the swinery is strengthened. Adding traditional Chinese medicine biological agent into daily feeding.
1. Using and using amount
The feed can be fed by mixed feed, or can be independently and slightly supplemented and sprinkled in a trough for feeding. 20 kg of traditional Chinese medicine biological agent is added into each ton of complete feed. The dosage of the first use can be increased by 2-4 times in the first 1 month before the first use and the first slaughter of the patients with serious peripheral epidemic situation. The feed can be used in various stages of piglets, pork pigs and sows, and does not need to stop during medication and immunization. Can be simply mixed with partial complete feed and then enters an automatic feeding system for application.
2. Feeding method
(1) The direct spreading and feeding method comprises the following steps: if the materials are mixed inconveniently, the traditional Chinese medicine biological agent can be independently and directly sprayed to a pork pig breeding area for feeding, the spraying proportion is fed into the area according to the use amount of 20 kilograms of the traditional Chinese medicine biological agent in 1 ton of feed, the traditional Chinese medicine biological agent is scattered as much as possible to ensure that each pork pig can eat the traditional Chinese medicine biological agent, the product is very fragrant, mellow and delicious, the pork pigs can eat the traditional Chinese medicine biological agent cleanly, and the traditional Chinese medicine biological agent can be sprayed and fed for 1 time every day.
(2) The method for using the product in drinking water comprises the following steps: the operation of the automatic drinking water system of the large-scale farm needs to put 20 kg of the traditional Chinese medicine biological agent into a gauze bag, immerse the gauze bag into 1 ton of water, rub the gauze bag back and forth for more than 3 minutes, most of the product can be dissolved into the water, and the residual undissolved residues are directly fed or stirred. 1 kg of brown sugar is added into each ton of drinking water, and the drinking effect for animals is better after the animals stand for more than half an hour; 20 kg of the traditional Chinese medicine biological preparation is directly poured into 1 ton of drinking water and then stirred for being drunk by the pork pigs at a time (1 kg of brown sugar is added for standing for more than half an hour, and the effect is better). The product has a large quantity of probiotics, and most of the Chinese herbal medicines can be released, so that good effect can be achieved by drinking water.
Application example of the traditional Chinese medicine biological preparation comprises the following steps:
1. using and using amount
The feed can be fed by mixed feed, or can be independently and slightly supplemented and sprinkled in a trough for feeding. 60-100 kg of traditional Chinese medicine biological agent is added into each ton of complete feed.
2. Feeding method
(1) The direct spreading and feeding method comprises the following steps: if the materials are mixed inconveniently, the traditional Chinese medicine biological agent can be independently and directly sprayed to a cattle and sheep breeding area for feeding, the spraying proportion is used for feeding the cattle and sheep according to the feeding area with the use amount of 60-100 kilograms of the traditional Chinese medicine biological agent in 1 ton of feed, the traditional Chinese medicine biological agent is scattered as much as possible to ensure that each cattle and sheep can eat the traditional Chinese medicine biological agent, the product is very fragrant, mellow and delicious, the cattle and sheep can eat the traditional Chinese medicine biological agent cleanly, and the traditional Chinese medicine biological agent can.
(2) The method for using the product in drinking water comprises the following steps: the operation of the automatic drinking water system of the large-scale farm needs to put 60-100 kg of the traditional Chinese medicine biological preparation into a gauze bag, immerse the gauze bag into 1 ton of water, rub the gauze bag back and forth for more than 3 minutes, most of the product can be dissolved into the water, and the residual undissolved residues are directly fed or stirred. 1 kg of brown sugar is added into each ton of drinking water, and the drinking effect for animals is better after the animals stand for more than half an hour; in a small-scale farm or a farm which does not automatically drink water, 60-100 kg of the traditional Chinese medicine biological agent is directly poured into 1 ton of drinking water and then stirred for drinking by animals at a time (1 kg of brown sugar is added and the effect is better when the animals stand for more than half an hour). The product has a large quantity of probiotics, and most of the Chinese herbal medicines can be released, so that good effect can be achieved by drinking water.
Application example three of the Chinese herbal biological agent (epidemic prevention of poultry):
1. using and using amount
The feed can be fed by mixed feed, or can be independently and slightly supplemented and sprinkled in a trough for feeding. 20 kg of traditional Chinese medicine biological agent is added into each ton of complete feed.
2. Feeding method
(1) The direct spreading and feeding method comprises the following steps: if the materials are mixed inconveniently, the traditional Chinese medicine biological agent can be independently and directly sprayed to a poultry breeding area for feeding, the spraying and feeding proportion is that the poultry can eat the traditional Chinese medicine biological agent in a feeding area with the use amount of 20 kilograms of the traditional Chinese medicine biological agent according to 1 ton of feed, the traditional Chinese medicine biological agent is scattered as much as possible, and the traditional Chinese medicine biological agent is sprayed and fed for 1 time every day.
(2) The method for using the product in drinking water comprises the following steps: the operation of the automatic drinking water system of the large-scale farm needs to put 20 kg of the traditional Chinese medicine biological agent into a gauze bag, immerse the gauze bag into 1 ton of water, rub the gauze bag back and forth for more than 3 minutes, most of the product can be dissolved into the water, and the residual undissolved residues are directly fed or stirred. 1 kg of brown sugar is added into each ton of drinking water, and the drinking effect for animals is better after the animals stand for more than half an hour; in a small-scale farm or a farm which does not automatically drink water, 20 kg of the traditional Chinese medicine biological agent is directly poured into 1 ton of drinking water and then stirred for drinking by poultry at a time (1 kg of brown sugar is added, and the effect is better when the poultry is static for more than half an hour). The product has a large quantity of probiotics, and most of the Chinese herbal medicines can be released, so that good effect can be achieved by drinking water.
The application example of the Chinese medicinal biological preparation is four (epidemic prevention of special animals):
1. using and using amount
The feed can be fed by mixed feed, or can be independently and slightly supplemented and sprinkled in a trough for feeding. 40 kg of traditional Chinese medicine biological agent is added into each ton of complete feed.
2. Feeding method
(1) The direct spreading and feeding method comprises the following steps: if the materials are mixed inconveniently, the traditional Chinese medicine biological agent can be independently and directly sprayed to a special animal breeding area for feeding, the spraying and feeding proportion is that each special animal can eat the feed according to 1 ton of the feed and the use amount of 40 kilograms of the traditional Chinese medicine biological agent in the feeding area, the feed is scattered as far as possible, and the feed is only needed to be sprayed and fed for 1 time every day.
(2) The method for using the product in drinking water comprises the following steps: the operation of the automatic drinking water system of the large-scale farm needs to put 40 kg of the traditional Chinese medicine biological preparation into a gauze bag, immerse the gauze bag into 1 ton of water, rub the gauze bag back and forth for more than 3 minutes, most of the product can be dissolved into the water, and the residual undissolved residues are directly fed or stirred. 1 kg of brown sugar is added into each ton of drinking water, and the drinking effect for animals is better after the animals stand for more than half an hour; a small-scale farm or a farm which does not automatically drink water is prepared by directly pouring 40 kg of the traditional Chinese medicine biological preparation into 1 ton of drinking water and stirring the mixture for drinking special animals at a time (1 kg of brown sugar is added, and the effect is better when the mixture is kept still for more than half an hour). The product has a large quantity of probiotics, and most of the Chinese herbal medicines can be released, so that good effect can be achieved by drinking water.
As described above, it will be apparent to those skilled in the art that other various modifications can be made based on the technical solution and the technical idea of the present invention, and all such modifications shall fall within the scope of the appended claims.
Claims (7)
1. A traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases is characterized in that: the preparation is prepared by using honeysuckle, weeping forsythia, common andrographis herb, indigowoad leaf, indigowoad root, natural indigo, cyrtomium rhizome, dandelion, Chinese violet, wild chrysanthemum flower, Indian buead, liquoric root, golden thread and cordyceps militaris as raw materials, extracting the raw materials of the traditional Chinese medicines to obtain a traditional Chinese medicine liquid, using the traditional Chinese medicine liquid as a liquid culture medium, then inoculating pleurotus ostreatus strains, enabling the liquid culture medium to overgrow with fungus balls after liquid submerged culture to obtain a traditional Chinese medicine liquid strain, inoculating the traditional Chinese medicine liquid strain into a biological strain, and continuously culturing to obtain a biological bacterium liquid; drying and crushing the traditional Chinese medicine residues after the traditional Chinese medicine juice is obtained by extraction, then mixing with auxiliary materials, sterilizing, inoculating with a ganoderma lucidum strain, then culturing until the traditional Chinese medicine residues overgrow with ganoderma lucidum mycelia to obtain a ganoderma lucidum traditional Chinese medicine complex, and finally adsorbing biological bacteria liquid by using the ganoderma lucidum traditional Chinese medicine complex for secondary fermentation to obtain the traditional Chinese medicine biological preparation capable of effectively preventing and treating animal epidemic diseases.
2. The traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases as claimed in claim 1, is characterized in that the mixture ratio of the traditional Chinese medicine components is as follows: 10-18 parts of honeysuckle, 10-15 parts of fructus forsythiae, 12-20 parts of common andrographis herb, 8-12 parts of folium isatidis, 8-10 parts of isatis root, 3-6 parts of indigo naturalis, 3-5 parts of cyrtomium rhizome, 2-4 parts of dandelion, 2-3 parts of Chinese violet, 5-8 parts of wild chrysanthemum flower, 6-10 parts of poria cocos, 4-6 parts of licorice leaves, 4-6 parts of coptis chinensis and 5-8 parts of cordyceps militaris.
3. The biological preparation of claim 1, wherein the extraction method of the Chinese medicinal juice comprises the following steps:
(1) raw material treatment: mixing the above Chinese medicinal materials, and pulverizing into powder capable of passing through 20-30 mesh sieve;
(2) and (3) extraction: according to the proportion of putting 5-10 kg of the crushed traditional Chinese medicine in 100 kg of water, putting the crushed traditional Chinese medicine and the water in a heating container together, then heating until the water is boiled, continuously heating until the water in the container is reduced by half, and finally filtering to obtain the traditional Chinese medicine juice.
4. The Chinese medicinal biological preparation for preventing and treating animal epidemic diseases according to claim 1, wherein the cultivation method of the Chinese medicinal liquid strain comprises the following steps:
(1) collecting strains: collecting Pleurotus species commonly used in the field as a bacterial source;
(2) preparing test tube species: 200 g of potato, 10 g of glucose, 20 g of agar, 500 ml of the traditional Chinese medicine juice and 500 ml of clear water, peeling the potato, cutting the potato into small pieces, putting the potato, the traditional Chinese medicine juice and the clear water into a heating container, heating until the water boils, adding the glucose and the agar, subpackaging the mixture into test tubes, sterilizing the test tubes to prepare inclined test tubes, and inoculating pleurotus strains into the inclined test tubes to cultivate the pleurotus strains to obtain test tube seeds;
(3) preparing a first-stage liquid strain: peeling potato 200 g, white sugar 10 g, peptone 5g, the Chinese medicinal juice 800 ml and water 200 ml, cutting the peeled potato into small pieces, placing the potato, the Chinese medicinal juice and clear water into a heating container, heating until the water is boiled, adding the white sugar and the peptone into a nutrient solution, subpackaging the nutrient solution into triangular flasks, and finally sterilizing, inoculating test tube seeds and culturing to obtain a primary liquid strain;
(4) preparing traditional Chinese medicine liquid strains: 100000 ml of the traditional Chinese medicine juice, 2000 g of brown sugar and 500 g of peptone, putting the traditional Chinese medicine juice, the brown sugar and the peptone into a fermentation tank, then sterilizing according to a conventional method, then inoculating a first-level liquid strain, and finally culturing to obtain a traditional Chinese medicine liquid strain.
5. The biological preparation according to claim 1, wherein the method for culturing the biological bacterial liquid comprises the following steps
(1) Collecting biological strains: collecting beneficial biological strains with effective viable count of more than or equal to 5 multiplied by 100/ml as a bacterial source;
(2) fermentation: 100000 ml of traditional Chinese medicine liquid strain, 5000 g of brown sugar and 2000 ml of biological strain, putting the brown sugar and the traditional Chinese medicine liquid strain into a fermentation container, stirring until the brown sugar is completely dissolved in the traditional Chinese medicine liquid strain, and putting the biological strain into the traditional Chinese medicine liquid strain for anaerobic fermentation for 6-10 days to obtain biological bacteria liquid.
6. The biological preparation of Chinese traditional medicine for preventing and treating animal epidemic disease as claimed in claim 1, wherein the cultivation method of the ganoderma lucidum traditional Chinese medicine complex is as follows:
(1) collecting ganoderma lucidum strains: collecting ganoderma lucidum strains commonly used in the field as a strain source;
(2) principle processing: drying the traditional Chinese medicine residue after the traditional Chinese medicine juice is obtained by extraction until the water content of the materials is lower than 20 percent for later use;
(3) the raw materials comprise the following components in percentage by weight: 70 parts of traditional Chinese medicine residues, 20 parts of bran and 10 parts of corn flour, and mixing the traditional Chinese medicine residues, the bran and the corn flour and uniformly stirring to obtain a mixed culture material;
(4) culturing ganoderma lucidum mycelia: adding appropriate amount of clear water into the mixed culture medium to make the water content of the mixed culture medium reach 55-60%, subpackaging in culture container, sterilizing according to conventional method, inoculating Ganoderma strain in sterile environment, and culturing until the mixed culture medium is full of Ganoderma mycelia to obtain Ganoderma traditional Chinese medicine complex.
7. The traditional Chinese medicine biological preparation for preventing and treating animal epidemic diseases according to claim 1, which is characterized in that the preparation method of the traditional Chinese medicine biological preparation is as follows:
(1) mixing raw materials: mixing Ganoderma traditional Chinese medicine complex and biological bacterial liquid, and stirring to make water content of the mixture reach 55-60%;
(2) fermentation: placing the mixed material in a clean fermentation chamber for semi-itching fermentation until white hypha is fully developed on the surface of the mixed material, and then completing fermentation;
(3) and (3) finished product: and drying the fermented mixed material at 50 ℃ until the water content of the material is lower than 8% to obtain the finished product of the traditional Chinese medicine biological preparation.
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