KR19990065207A - Hair loss prevention and hair growth promoter - Google Patents

Abstract

A hair loss prevention and hair growth promoting agent based on herbal ingredients such as cedar leaf, bark skin, ginseng, sewage, johyeop, baekbaekpi, hwamine, AES, M.K, OP, and a method for producing the same are disclosed.

Description

Hair loss prevention and hair growth promoter

The present invention relates to a hair loss prevention and hair growth promoting agent (hereinafter referred to as a hair growth promoting agent) having an effect such as strong hair growth, hair loss prevention, dandruff occurrence and itching suppression. More specifically, the present invention relates to a hair loss prevention and hair growth promoting agent, including baekbaekbyeon, neck bark, ginseng, sewage, johyeop, Sangbaekpi, hwamine, AES, M.K and the like.

Currently, various methods have been tried to prevent hair loss and to treat baldness, including the development of anti-hair loss agents and hair growth promoters, but the developed products have not been shown to be effective enough.

Unlike conventional products, this hair growth promoter is a natural herbal ingredient that does not have any toxic or side effects on the human body, such as cedar leaf, bark skin, ginseng, sewage, johyeop, baekbaek skin, hwamain, and is not a form that is applied and taken Developed as a shampoo, it shows excellent effects compared to products of the prior art by preventing hair loss and hair growth effect of the natural herbal ingredient itself and increase of the skin penetration effect due to the shampoo.

The present invention relates to a hair growth promoter comprising the following a) to h).

a) 4-5% by weight of the temporal lobe

b) 4-6% by weight of neck skin

c) 8-9% by weight of crude

d) 2% by weight of sewage

e) 4-5% by weight of phosphorus

f) 4 to 6% by weight of lettuce

g) 2% by weight of ginseng

h) 0.1% by weight of M.K

The percentage is based on the weight of the hair growth promoter, and in the herbal ingredient, it indicates the weight ratio of each component as an extract.

The composition may contain a solvent and additives suitable for its formulation.

Various components necessary for the hair growth promoting agent of the present invention are well known in the art and are commercially available as herbal ingredients.

Bioate Orientalis Folium, which can be used in the hair growth promoter of the present invention, contains tujene, tujone, pinene, quercetin, myricetin and vitamin C. Is doing, there is development, hemostatic action.

Moutan Cortex Radicis, which may be used in the hair growth promoter of the present invention, includes, as its components, peonolide, peonol, and paeoniflorin. As a result, it was found that the material extracted from the bark skin has an effect of promoting the growth of dermal papilla cells. Dermal papilla cells are located in the root of the roots (生髮 根部), it serves to inhibit the growth of hair and hair growth (hair). Thus, the dermal papilla cells are called the head of the hair growth field, and once all of the milk is small, the hair growth field is impaired and the hair loss symptoms become more severe. If the hair is thicker and thicker, it should promote the growth of the hair papilla cells as well as the growth of the hair cells.

Gleditschiae Fructus of the present invention contains Gleditschia saponin (C ₅₉ H ₁₀₀ O ₂₀ ), alkaloids, etc., the origin is Gledigenin (Gledigenin, C ₃₀ H ₄₈ O ₃ ), It also contains Gledinin, a type of Reddishia saponin, and Gledithia saponin of origin (C ₃₀ H ₄₈ O ₄ ). It has the effect of lowering the surface tension. May be used. As a result of the test, the coarse solution has an inhibitory effect on certain skin fungi and is evaluated to have good development.

In the sewage (何首烏, Polygoni Multiflori Radix) adopted in the present invention, Chrysophanol, Emmodin, rhein, physcion, 2,3,5,4-tetrahydroxystea Ben-2-O-β-D-glucoside, lecithin, etc., which are used for the treatment of water repellent, white worm, and anti-aging. Trace elements such as Sr, Zn, Cu, Fe, Ti, etc. are thought to help prevent aging.

Hwamine (火 채택 仁, Cannabis Semen) used in the hair growth promoting agent of the present invention contains about 30% fat and 19% contains protein, a small amount of volatile substances (essential oil), vitamin E, lecithin, It plays an important role in the treatment of hair diseases and at the same time provides very good nutrition and shine to the hair.

Mori Cortex that can be used as a component of the hair growth promoter of the present invention is a volatile substance (essential oil), pectin, pectin, morusin, mulberrochromene, α, β -Contains amirin, hair loss treatment.

Ginseng (Radix Ginseng) that can be used in the hair growth promoter of the present invention is a saponin, Ginsenosides Rb ₁ , Rg ₁ , Rg ₂ and a small amount of saponin Ginsenosides Ra, Rb ₂ , Rb, Re as the main component and also Falkari It contains Falcarinol (Panaxynol), β-sitosterol, about 0.025% of Dowsterin, vitamin B group, and prostisol, which are used to treat alopecia areata due to the action of pterygium. do.

MK (Magic Ketone) used in the present invention is Has a chemical structure of (R is an alkyl group), and serves as a skin penetration absorbent.

Hair promoters of the present invention can be prepared by a method comprising the following steps a) to d).

a) Prepare the basic solution by heating and dissolving each extract of Johyup and Sangbaekpi with water and AES solution.

b) The main solution is prepared by mixing the extracts of cypresses, bark skins, sewage, mein and ginseng with M.K and OP solutions.

c) mixing the main solution with the main solution.

d) addition of additives.

AES (Alkyl ethoxysulgote, molecular formula RO (CH ₂ CH ₂ ) _n SO ₃ Na, pH 8-9) used in the method of the present invention serves to remove the dirt with a colorless or pale yellow mucus solution.

OP used in this method means a solution of OP-10 (Alkyl phenyl ethoxylate, RC ₆ H ₄ O (CH ₂ CH ₂ O) nOH, n = 10, PH = 6 ~ 7), MK is dissolved in OP Used in form.

The above-mentioned additives include preservatives such as potassium sorbate (CH ₃ CH = CHCH = CHCOOK) and sodium benzoate (C ₆ H ₅ CO ₂ Na), and flavorings (food additives) such as 6133 lemon flavor.

Example Preparation of Hair Regrowth

1. Material

White leaf, bark skin, Johyup, white skin, Hwamine, Sewao, Ginseng, M.K, OP-10, AES, Additive

2. Preparation of Basic Solution

Into a 2-liter flask, 500 g of AES, 1,500 cc of water, 250 g of flake extract and 150 g of shredded skin are stirred and heated and dissolved so that it does not exceed 100 ° C. The heating is stopped after the AES has completely dissolved.

3. Preparation of main solution

125 g of leafy white leaf, 150 g of bark peel, 60 g of sewage, 125 g of ginseng and 60 g of ginseng, respectively, are mixed with 30 cc of M.K OP 10% (MK and 10% by weight) of solution (15 cc if M.K OP 20%).

4. Finished product manufacturing

The basic solution prepared above is cooled to 70 ° C. and then mixed with the main solution and cooled to 30 ° C. At this point, add 1/4 teaspoon of preservative and add fragrance when it reaches 20 ℃.

Example 2 Preparation of Extracts of Materials

When extracting the solution, the ratio of 95% ethanol and distilled water is 3: 1.

(1) the temporal lobe

Using only leaves, rinse twice with clear water and dry under direct sunlight. 5 kg of dried leaves are placed in a 25 L container, 70% ethanol is soaked (approximately 16 L) in the leaves, and the lid is closed and stored for 1 week to prevent ethanol from flying away. Shake the jar 2-3 times a day.

Transfer the contents stored for one week to a clean, dry container. You can use gauze or a mosquito net to keep the debris out of the jar.

(2) ginseng

Add 10 g of chopped ginseng to 250 g of ethanol and seal for 24 hours.

The extracted solution is filtered, and the filtered residue is again closed by sealing with 250 g of ethanol (70%) for 24 hours.

After extracting and filtering the residues in the same manner as above, the three filtrates are mixed.

(3) neck skin

Put 10g of bark into 500g of distilled water and heat it for 20-25 minutes on low heat. After filtering the heating solution, the primary filtrate is stored sealed in a brown glass bottle.

The filtered residue is heated in 450 g distilled water again for 15 minutes and filtered to obtain a secondary filtrate, and the primary and secondary filtrates are mixed.

(4) flower

1 kg of hwamin, 8 kg of distilled water, 2 L of ethanol (95%) were locked in a ceramic vessel for 24 hours, and then the solution was filtered to obtain a filtrate.

(5) Shouao

a. 10 g of chopped sewage was immersed in 750 cc of ethanol (70%) and soaked for 48 hours, and then the solution was filtered to obtain a primary filtrate. Then, 700 cc of ethanol (70%) was added to the first filtered residue and soaked for 48 hours. After that, the mixture is filtered again to obtain a secondary filtrate, and the primary and secondary filtrates are mixed.

b. Soak 20 g of sewage in 1 liter of distilled water for 24 hours, and boil for 30 to 40 minutes. After filtration of the boiled solution, the first filtrate was obtained, and 800cc of distilled water was again put in the remaining dregs, which was immersed for 24 hours, boiled for 30 to 40 minutes, filtered to obtain a second filtrate, and the first and second filtrates were mixed. do.

The solutions obtained in a and b are mixed.

(6) cooperative

Finely chopped and washed 38kg of coarse water soaked in 680kg of water for 24 hours, heated for 20-30 minutes and filtered to obtain a primary filtrate.

Put 560kg of water into the remaining residue after filtration and boil again for 15-20 minutes, and then filtered again to obtain a secondary filtrate.

The first and second filtrates are mixed.

(7) white skin

10kg of baekpipi into 250kg of water and stored for 24 hours, heated on low heat for 20-25 minutes, and then filtered to obtain a filtrate.

(8) M.K. 10% OP solution

M.K. Add 100g to 1kg OP solution and dissolve.

If it does not melt well, it is heated to 100 ℃ or less.

Example 3: Toxicity Test of Products

The following standards were applied to test the toxicity of this product manufactured from herbal ingredients.

1. The method cited in the standard

GB601 Chemical reagent standard solution manufacturing method

GB5009.11-85 Total Amount of Food Arsenic (AS)

GB5009.12-85 Total amount of PB

1990 version of the People's Republic of China, the method of measuring the amount of ethyl alcohol (ethyl alchohol)

1990, sterility test method of the People's Republic of China

Determination of Saponin Content in Ginseng

2. Test method

2.1 Color and Transparency Inspection: Pour 50 ml of this medicine into a clean 100 ml flask and measure the color and clarity visually in a bright place.

2.2 Open the odor lid and smell it carefully and inspect it for any unusual odors.

3. pH measurement

3.1 Mechanical precision measuring instrument (Ph measuring instrument)

3.2 Measurement 100 ml of this drug is measured. ± 0.5 error

3.3 Arsenic Measurement As measured by GB5009.11

Measured by GB5009.12

3.4 Bacterial count measurement as measured by GB4789.2

3.5 Coliform Count Measurement by GB4789.3

3.6 Pathogen count measured by GB4789.4

3.7 Sterility Testing 1990 Version of the People's Republic of China

4. Test result

Item result Color Pale greenish mucus smell Natural flavor transparency There may be some sediment

Item result Degree PH 6.5-7 Ginseng Saponin Content 1 ± 0.5 alchohol content 0.6 to 1.0 Arsenic (As) mg / kg radish Pb mg / kg radish

Item result Total bacteria / ml 100 Coliform count / ml 6 Pathogens radish Sterility Test pass

As can be seen from the above data, the hair growth promoter of the present invention shows that it is an excellent product with no toxicity or side effects to the human body.

Claims (3)

Hair loss prevention and hair growth promoting agent containing following a) -h). a) 4-5% by weight of the temporal lobe b) 4-6% by weight of neck skin c) 8-9% by weight of crude d) 2% by weight of sewage e) 4-5% by weight of phosphorus f) 4 to 6% by weight of lettuce g) 2% by weight of ginseng h) 0.1% by weight of M.K Method for producing a hair loss prevention and hair growth promoter comprising the following steps a) to d). a) Prepare the basic solution by heating and dissolving each extract of Johyup and Sangbaekpi with water and AES solution. b) The main solution is prepared by mixing the extracts of cypresses, bark skins, sewage, mein and ginseng with M.K and OP solutions. c) mixing the main solution with the main solution. d) addition of additives. The method according to claim 2, wherein the M.K and OP solutions are used as M.K 10% to 20% OP solutions.