KR102958459B1 - 약제학적 조성물 - Google Patents

약제학적 조성물

Info

Publication number
KR102958459B1
KR102958459B1 KR1020217023943A KR20217023943A KR102958459B1 KR 102958459 B1 KR102958459 B1 KR 102958459B1 KR 1020217023943 A KR1020217023943 A KR 1020217023943A KR 20217023943 A KR20217023943 A KR 20217023943A KR 102958459 B1 KR102958459 B1 KR 102958459B1
Authority
KR
South Korea
Prior art keywords
copolymer
pharmaceutical composition
kda
composition according
branched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020217023943A
Other languages
English (en)
Korean (ko)
Other versions
KR20210113251A (ko
Inventor
크리스또프 로베르즈
아돌포 로뻬즈 노히에갸
쟝 마뉘엘 크로
쥴리엣뜨 세행두
뮤리엘 오스터
팡 리우
샤를로트 몰리니에
실베스트르 그리조
타사 브리닉
페이페이 응
엘리스 구에가인
마리-에메랑티엔 카뇽
Original Assignee
메딘셀 에스.에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 메딘셀 에스.에이. filed Critical 메딘셀 에스.에이.
Publication of KR20210113251A publication Critical patent/KR20210113251A/ko
Application granted granted Critical
Publication of KR102958459B1 publication Critical patent/KR102958459B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020217023943A 2019-01-08 2020-01-08 약제학적 조성물 Active KR102958459B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1900258.3A GB201900258D0 (en) 2019-01-08 2019-01-08 Pharmaceutical composition
GB1900258.3 2019-01-08
PCT/EP2020/050333 WO2020144239A1 (en) 2019-01-08 2020-01-08 Pharmaceutical composition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020267012731A Division KR20260061472A (ko) 2019-01-08 2020-01-08 약제학적 조성물

Publications (2)

Publication Number Publication Date
KR20210113251A KR20210113251A (ko) 2021-09-15
KR102958459B1 true KR102958459B1 (ko) 2026-04-29

Family

ID=65528088

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217023943A Active KR102958459B1 (ko) 2019-01-08 2020-01-08 약제학적 조성물

Country Status (25)

Country Link
US (3) US12485139B2 (enExample)
EP (2) EP4289429A3 (enExample)
JP (2) JP7680355B2 (enExample)
KR (1) KR102958459B1 (enExample)
CN (1) CN113543775B (enExample)
AU (1) AU2020205438B8 (enExample)
BR (1) BR112021013456A2 (enExample)
CA (1) CA3125372A1 (enExample)
DK (1) DK3908321T3 (enExample)
EA (1) EA202191603A1 (enExample)
ES (1) ES2968432T3 (enExample)
FI (1) FI3908321T3 (enExample)
GB (1) GB201900258D0 (enExample)
HR (1) HRP20231667T1 (enExample)
HU (1) HUE064916T2 (enExample)
LT (1) LT3908321T (enExample)
MX (1) MX2021008248A (enExample)
PH (1) PH12021551642A1 (enExample)
PL (1) PL3908321T3 (enExample)
PT (1) PT3908321T (enExample)
RS (1) RS65067B1 (enExample)
SI (1) SI3908321T1 (enExample)
SM (1) SMT202400011T1 (enExample)
WO (1) WO2020144239A1 (enExample)
ZA (1) ZA202104704B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022069799A1 (en) * 2020-10-01 2022-04-07 Turku University of Applied Sciences Ltd A hydrogel material
US20250009647A1 (en) 2021-08-05 2025-01-09 Medincell S.A. Pharmaceutical composition
WO2025104289A1 (en) 2023-11-17 2025-05-22 Medincell S.A. Antineoplastic combinations
WO2026013080A1 (en) 2024-07-08 2026-01-15 InnoCore Technologies Holding B.V. Pharmaceutical composition based on biodegradable polymers comprising polyoxazoline

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2016A (en) 1841-03-26 Mode of constructing fireplaces and chimney-staoks ii
US5225521A (en) 1991-12-31 1993-07-06 E. I. Du Pont De Nemours And Company Star-shaped hydroxyacid polymers
FR2741628B1 (fr) 1995-11-29 1998-02-06 Centre Nat Rech Scient Nouveaux hydrogels a base de copolymeres trisequences et leur application notamment a la liberation progressive de principes actifs
AU4648697A (en) 1996-09-23 1998-04-14 Chandrashekar Pathak Methods and devices for preparing protein concentrates
US6461631B1 (en) 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
KR100416242B1 (ko) 1999-12-22 2004-01-31 주식회사 삼양사 약물전달체용 생분해성 블록 공중합체의 액체 조성물 및이의 제조방법
US7265186B2 (en) 2001-01-19 2007-09-04 Nektar Therapeutics Al, Corporation Multi-arm block copolymers as drug delivery vehicles
ES2358416T3 (es) 2001-10-30 2011-05-10 Novartis Ag Formulaciones de liberación prolongada de iloperidona y polímero en forma de estrella.
US7649023B2 (en) 2002-06-11 2010-01-19 Novartis Ag Biodegradable block copolymeric compositions for drug delivery
US20050255091A1 (en) 2004-05-14 2005-11-17 Loomis Gary L Hydrogels for biomedical applications
CN101541857B (zh) * 2006-11-27 2012-12-12 阿克塔马克斯手术器材有限责任公司 多官能聚环氧烷、水凝胶和组织粘合剂
US9248165B2 (en) * 2008-11-05 2016-02-02 Hancock-Jaffe Laboratories, Inc. Composite containing collagen and elastin as a dermal expander and tissue filler
US20110070320A1 (en) 2009-09-23 2011-03-24 Soonkap Hahn Biodegradable thermoresponsive 3-arm polyethylene glycol poly(lactide-co-glycolide) copolymer for ginseng administration
MX347090B (es) 2010-12-29 2017-04-11 Medincell Composiciones de suministro de farmacos biodegradables.
CN102432852B (zh) 2011-08-25 2013-10-16 复旦大学 一种聚乳酸基立构复合交联共聚物及其制备方法
JP6134788B2 (ja) 2012-06-27 2017-05-24 メドインセルル 疎水性組成物のための生分解性薬物送達
WO2014165923A1 (en) 2013-04-11 2014-10-16 Commonwealth Scientific And Industrial Research Organisation Composition for controlled delivery of bioactive agents
CA3174824A1 (en) * 2014-04-21 2015-10-29 Heron Therapeutics, Inc. Long-acting polymeric delivery systems
CN103976976B (zh) 2014-06-03 2016-05-11 长春理工大学 一种包载重组人生长激素缓释药物微囊的制法
EP4374861A3 (en) 2015-11-16 2024-08-07 MedinCell S.A. A method for morselizing and/or targeting pharmaceutically active principles to synovial tissue
CN106543454B (zh) 2016-11-25 2019-05-28 山东师范大学 一种低溶胀可生物降解医用光聚合型水凝胶及其制备方法
CN106832844B (zh) 2017-02-10 2018-11-20 四川大学 一种四臂peg-pcl、氧化石墨烯复合材料及其制备方法
ES3015765T3 (en) 2017-07-17 2025-05-07 Medincell S A Pharmaceutical composition
CN108586775B (zh) 2018-05-04 2019-11-12 四川大学 可用于眼内长期填充的原位交联超支化聚醚类水凝胶及其制备方法

Also Published As

Publication number Publication date
GB201900258D0 (en) 2019-02-27
MX2021008248A (es) 2021-10-13
BR112021013456A2 (pt) 2021-09-14
CN113543775A (zh) 2021-10-22
EA202191603A1 (ru) 2021-10-20
CN113543775B (zh) 2023-11-24
ES2968432T3 (es) 2024-05-09
EP4289429A2 (en) 2023-12-13
FI3908321T3 (fi) 2024-01-11
EP3908321A1 (en) 2021-11-17
KR20210113251A (ko) 2021-09-15
SI3908321T1 (sl) 2024-03-29
PT3908321T (pt) 2024-01-15
JP7680355B2 (ja) 2025-05-20
HRP20231667T1 (hr) 2024-03-15
RS65067B1 (sr) 2024-02-29
EP4289429A3 (en) 2024-03-20
SMT202400011T1 (it) 2024-03-13
AU2020205438A1 (en) 2021-07-29
US20260115226A1 (en) 2026-04-30
AU2020205438B9 (en) 2025-03-27
ZA202104704B (en) 2024-11-27
DK3908321T3 (da) 2024-01-15
EP3908321B1 (en) 2023-11-15
PL3908321T3 (pl) 2024-03-25
AU2020205438B8 (en) 2025-03-27
AU2020205438B2 (en) 2025-02-06
WO2020144239A1 (en) 2020-07-16
US12485139B2 (en) 2025-12-02
US12427165B2 (en) 2025-09-30
HUE064916T2 (hu) 2024-04-28
LT3908321T (lt) 2024-01-25
US20240293444A1 (en) 2024-09-05
US20220118003A1 (en) 2022-04-21
CA3125372A1 (en) 2020-07-16
PH12021551642A1 (en) 2022-05-23
JP2025066716A (ja) 2025-04-23
JP2022517939A (ja) 2022-03-11

Similar Documents

Publication Publication Date Title
US12427165B2 (en) Pharmaceutical composition
US11666527B2 (en) Biodegradable block copolymer drug delivery composition
KR20260061472A (ko) 약제학적 조성물
US20230321245A1 (en) Pharmaceutical composition
EA045374B1 (ru) Фармацевтическая композиция
HK40063230B (en) Pharmaceutical composition
HK40063230A (en) Pharmaceutical composition
EA052815B1 (ru) Фармацевтическая композиция
EA045044B1 (ru) Смеси биоразлагаемых композиций для доставки лекарственных средств для модулирования кинетики высвобождения из лекарственного средства по меньшей мере одного активного ингредиента
KR20240042032A (ko) 약제학적 조성물

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

D22 Grant of ip right intended

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D22-EXM-PE0701 (AS PROVIDED BY THE NATIONAL OFFICE)

PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

A16 Divisional, continuation or continuation in part application filed

Free format text: ST27 STATUS EVENT CODE: A-0-1-A10-A16-DIV-PA0104 (AS PROVIDED BY THE NATIONAL OFFICE)

PA0104 Divisional application for international application

St.27 status event code: A-0-1-A10-A16-div-PA0104

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

Q13 Ip right document published

Free format text: ST27 STATUS EVENT CODE: A-4-4-Q10-Q13-NAP-PG1601 (AS PROVIDED BY THE NATIONAL OFFICE)