KR102944729B1 - 초역치 저주파 전기 자극에 의한 신경 차단 - Google Patents

초역치 저주파 전기 자극에 의한 신경 차단

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Publication number
KR102944729B1
KR102944729B1 KR1020227002367A KR20227002367A KR102944729B1 KR 102944729 B1 KR102944729 B1 KR 102944729B1 KR 1020227002367 A KR1020227002367 A KR 1020227002367A KR 20227002367 A KR20227002367 A KR 20227002367A KR 102944729 B1 KR102944729 B1 KR 102944729B1
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South Korea
Prior art keywords
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nerve
minutes
stimulation
intensity
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KR1020227002367A
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English (en)
Korean (ko)
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KR20220035140A (ko
Inventor
창펑 타이
Original Assignee
유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션
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Publication of KR20220035140A publication Critical patent/KR20220035140A/ko
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36034—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36062—Spinal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A61N1/36153—Voltage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A61N1/36157—Current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36171—Frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36178—Burst or pulse train parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Electrotherapy Devices (AREA)
KR1020227002367A 2019-07-03 2020-06-30 초역치 저주파 전기 자극에 의한 신경 차단 Active KR102944729B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962870230P 2019-07-03 2019-07-03
US62/870,230 2019-07-03
PCT/US2020/040288 WO2021003151A1 (en) 2019-07-03 2020-06-30 Neural block by super-threshold low frequency electrical stimulation

Publications (2)

Publication Number Publication Date
KR20220035140A KR20220035140A (ko) 2022-03-21
KR102944729B1 true KR102944729B1 (ko) 2026-03-30

Family

ID=74101293

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227002367A Active KR102944729B1 (ko) 2019-07-03 2020-06-30 초역치 저주파 전기 자극에 의한 신경 차단

Country Status (9)

Country Link
US (1) US20220395686A1 (cg-RX-API-DMAC7.html)
EP (1) EP3993865A4 (cg-RX-API-DMAC7.html)
JP (1) JP7609359B2 (cg-RX-API-DMAC7.html)
KR (1) KR102944729B1 (cg-RX-API-DMAC7.html)
CN (1) CN114286705A (cg-RX-API-DMAC7.html)
AU (1) AU2020300506B2 (cg-RX-API-DMAC7.html)
BR (1) BR112021026805A2 (cg-RX-API-DMAC7.html)
CA (1) CA3145807A1 (cg-RX-API-DMAC7.html)
WO (1) WO2021003151A1 (cg-RX-API-DMAC7.html)

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US11413458B2 (en) 2011-05-19 2022-08-16 Neuros Medical, Inc. Nerve cuff electrode for neuromodulation in large human nerve trunks
AU2021219722A1 (en) 2020-02-11 2022-09-08 Neuros Medical, Inc. System and method for quantifying qualitative patient-reported data sets
IL305807A (en) 2021-03-12 2023-11-01 Amber Therapeutics Ltd Systems for controlling urinary incontinence
CN118103107A (zh) * 2021-10-14 2024-05-28 高等教育联邦系统-匹兹堡大学 肠道功能和性功能的骶神经调节

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JP2017502786A (ja) 2014-01-17 2017-01-26 カーディアック ペースメイカーズ， インコーポレイテッド 神経連絡をブロックする枯渇ブロック
US20170182319A1 (en) * 2007-08-02 2017-06-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education "Methods and Systems for Achieving a Physiological Response by Pudendal Nerve Stimulation and Blockade"

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US6393323B1 (en) * 2000-01-31 2002-05-21 Mcgill University Electronic stimulator implant for modulating and synchronizing bladder and sphincter function
US6928320B2 (en) * 2001-05-17 2005-08-09 Medtronic, Inc. Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated
US7328069B2 (en) * 2002-09-06 2008-02-05 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by electrical stimulation of and the delivery of drugs to the left and right pudendal nerves
US20050070970A1 (en) * 2003-09-29 2005-03-31 Knudson Mark B. Movement disorder stimulation with neural block
US20070073354A1 (en) * 2005-09-26 2007-03-29 Knudson Mark B Neural blocking therapy
US9020597B2 (en) * 2008-11-12 2015-04-28 Endostim, Inc. Device and implantation system for electrical stimulation of biological systems
US8195287B2 (en) * 2007-12-05 2012-06-05 The Invention Science Fund I, Llc Method for electrical modulation of neural conduction
US20090254144A1 (en) * 2008-04-02 2009-10-08 Case Western Reserve University System and Method of Bladder and Sphincter Control
WO2010067360A2 (en) * 2008-12-09 2010-06-17 Nephera Ltd. Stimulation of the urinary system
US9174045B2 (en) * 2009-03-20 2015-11-03 ElectroCore, LLC Non-invasive electrical and magnetic nerve stimulators used to treat overactive bladder and urinary incontinence
WO2016039768A1 (en) * 2014-09-12 2016-03-17 Neuros Medical, Inc Nerve cuff electrode for neuromodulation in large human nerve trunks
US10195434B2 (en) * 2012-06-15 2019-02-05 Case Western Reserve University Treatment of pain using electrical nerve conduction block
US9511230B2 (en) * 2013-11-08 2016-12-06 Nuvectra Corporation Implantable medical lead for stimulation of multiple nerves
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US20060184211A1 (en) 2004-01-22 2006-08-17 Gaunt Robert A Method of routing electrical current to bodily tissues via implanted passive conductors
US20170182319A1 (en) * 2007-08-02 2017-06-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education "Methods and Systems for Achieving a Physiological Response by Pudendal Nerve Stimulation and Blockade"
JP2017502786A (ja) 2014-01-17 2017-01-26 カーディアック ペースメイカーズ， インコーポレイテッド 神経連絡をブロックする枯渇ブロック

Also Published As

Publication number Publication date
EP3993865A4 (en) 2023-07-19
CN114286705A (zh) 2022-04-05
US20220395686A1 (en) 2022-12-15
AU2020300506A1 (en) 2022-01-27
BR112021026805A2 (pt) 2022-02-15
JP2022539172A (ja) 2022-09-07
WO2021003151A1 (en) 2021-01-07
EP3993865A1 (en) 2022-05-11
CA3145807A1 (en) 2021-01-07
AU2020300506B2 (en) 2025-09-04
JP7609359B2 (ja) 2025-01-07
KR20220035140A (ko) 2022-03-21

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