KR102901842B1 - 암 전이의 치료를 위한 키나제의 표적화 - Google Patents

암 전이의 치료를 위한 키나제의 표적화

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Publication number
KR102901842B1
KR102901842B1 KR1020207004184A KR20207004184A KR102901842B1 KR 102901842 B1 KR102901842 B1 KR 102901842B1 KR 1020207004184 A KR1020207004184 A KR 1020207004184A KR 20207004184 A KR20207004184 A KR 20207004184A KR 102901842 B1 KR102901842 B1 KR 102901842B1
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South Korea
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delete delete
kinase
kinase inhibitor
cdk5
cancer
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KR20200040763A (ko
Inventor
디후아 유
프랭크 로웨리
첸유 장
수닐 아차리아
핑 리
Original Assignee
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템
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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
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  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020207004184A 2017-08-11 2018-08-10 암 전이의 치료를 위한 키나제의 표적화 Active KR102901842B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762544597P 2017-08-11 2017-08-11
US62/544,597 2017-08-11
PCT/US2018/046329 WO2019033041A1 (en) 2017-08-11 2018-08-10 TARGETING KINASES FOR THE TREATMENT OF CANCER METASTASES

Publications (2)

Publication Number Publication Date
KR20200040763A KR20200040763A (ko) 2020-04-20
KR102901842B1 true KR102901842B1 (ko) 2025-12-19

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Country Status (8)

Country Link
US (1) US11406643B2 (https=)
EP (2) EP3665482A4 (https=)
JP (2) JP2020530467A (https=)
KR (1) KR102901842B1 (https=)
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US20200197407A1 (en) 2020-06-25
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