KR102891465B1 - 뇌졸중으로부터의 회복을 위한 방법 및 조성물 - Google Patents

뇌졸중으로부터의 회복을 위한 방법 및 조성물

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Publication number
KR102891465B1
KR102891465B1 KR1020187012006A KR20187012006A KR102891465B1 KR 102891465 B1 KR102891465 B1 KR 102891465B1 KR 1020187012006 A KR1020187012006 A KR 1020187012006A KR 20187012006 A KR20187012006 A KR 20187012006A KR 102891465 B1 KR102891465 B1 KR 102891465B1
Authority
KR
South Korea
Prior art keywords
stroke
pharmaceutical composition
composition according
hours
onset
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020187012006A
Other languages
English (en)
Korean (ko)
Other versions
KR20180101322A (ko
Inventor
존 자한기르 알람
Original Assignee
이아이피 파마 엘엘씨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이아이피 파마 엘엘씨 filed Critical 이아이피 파마 엘엘씨
Publication of KR20180101322A publication Critical patent/KR20180101322A/ko
Application granted granted Critical
Publication of KR102891465B1 publication Critical patent/KR102891465B1/ko
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020187012006A 2015-10-26 2016-10-26 뇌졸중으로부터의 회복을 위한 방법 및 조성물 Active KR102891465B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562246574P 2015-10-26 2015-10-26
US62/246,574 2015-10-26
PCT/US2016/058804 WO2017075013A1 (en) 2015-10-26 2016-10-26 Methods and compositions for recovery from stroke

Publications (2)

Publication Number Publication Date
KR20180101322A KR20180101322A (ko) 2018-09-12
KR102891465B1 true KR102891465B1 (ko) 2025-11-25

Family

ID=58631977

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020187012006A Active KR102891465B1 (ko) 2015-10-26 2016-10-26 뇌졸중으로부터의 회복을 위한 방법 및 조성물

Country Status (5)

Country Link
EP (1) EP3368040B1 (https=)
JP (1) JP6889493B2 (https=)
KR (1) KR102891465B1 (https=)
CN (1) CN108348524A (https=)
WO (1) WO2017075013A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
WO2019071147A1 (en) 2017-10-05 2019-04-11 Fulcrum Therapeutics, Inc. INHIBITORS OF KINASE P38 REDUCING EXPRESSION OF DUX4 GENE AND DOWNSTREAM GENES FOR THE TREATMENT OF FSHD
WO2020108659A1 (zh) * 2018-11-30 2020-06-04 上海医药集团股份有限公司 含氮杂环类化合物及其组合物、制备方法和应用
JP7384341B1 (ja) 2023-07-07 2023-11-21 学校法人冬木学園 脳卒中患者の身体の痛みの改善を目的とするリハビリテーションの効果を予測するための方法、及び、システム

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016007616A1 (en) 2014-07-09 2016-01-14 Eip Pharma, Llc Methods for treating neurologic disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6608060B1 (en) 1996-12-18 2003-08-19 Vertex Pharmaceuticals Incorporated Inhibitors of p38
US20040082509A1 (en) * 1999-10-12 2004-04-29 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US7998507B2 (en) * 2000-09-21 2011-08-16 Elan Pharma International Ltd. Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors
DE60319073T2 (de) * 2002-03-20 2009-02-05 Elan Pharma International Ltd. Nanopartikelzusammensetzungen von mitogen-aktivierten protein (map) kinase inhibitoren
WO2003084524A1 (en) * 2002-03-29 2003-10-16 Neurogen Corporation Combination therapy for the treatment of conditions with pathogenic inflammatory components
CA2726588C (en) * 2008-06-03 2019-04-16 Karl Kossen Compounds and methods for treating inflammatory and fibrotic disorders
US9816336B2 (en) 2014-07-08 2017-11-14 Halliburton Energy Services, Inc. Real time conformance

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016007616A1 (en) 2014-07-09 2016-01-14 Eip Pharma, Llc Methods for treating neurologic disorders

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VX-745 Vertex Pharmaceuticals, Current Opinion in Investigational Drugs, 2(8):1070-1076 (2001)*

Also Published As

Publication number Publication date
EP3368040A1 (en) 2018-09-05
KR20180101322A (ko) 2018-09-12
EP3368040A4 (en) 2019-05-29
EP3368040B1 (en) 2022-08-17
JP2018531961A (ja) 2018-11-01
CN108348524A (zh) 2018-07-31
JP6889493B2 (ja) 2021-06-18
WO2017075013A1 (en) 2017-05-04

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