KR102885025B1 - 유전적 조절 - Google Patents

유전적 조절

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Publication number
KR102885025B1
KR102885025B1 KR1020207012736A KR20207012736A KR102885025B1 KR 102885025 B1 KR102885025 B1 KR 102885025B1 KR 1020207012736 A KR1020207012736 A KR 1020207012736A KR 20207012736 A KR20207012736 A KR 20207012736A KR 102885025 B1 KR102885025 B1 KR 102885025B1
Authority
KR
South Korea
Prior art keywords
dna
homo sapiens
chromosomal
interactions
nucleic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020207012736A
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English (en)
Korean (ko)
Other versions
KR20200081380A (ko
Inventor
알렉상드르 아쿨리츠체프
어로울 셀밤 라마다스
이완 헌터
Original Assignee
옥스포드 바이오다이나믹스 피엘씨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 옥스포드 바이오다이나믹스 피엘씨 filed Critical 옥스포드 바이오다이나믹스 피엘씨
Publication of KR20200081380A publication Critical patent/KR20200081380A/ko
Application granted granted Critical
Publication of KR102885025B1 publication Critical patent/KR102885025B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020207012736A 2017-11-03 2018-11-02 유전적 조절 Active KR102885025B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762581287P 2017-11-03 2017-11-03
US62/581,287 2017-11-03
GBPCT/GB2018/052818 2018-10-03
GB2018052818 2018-10-03
PCT/GB2018/053196 WO2019086898A2 (en) 2017-11-03 2018-11-02 Genetic regulation

Publications (2)

Publication Number Publication Date
KR20200081380A KR20200081380A (ko) 2020-07-07
KR102885025B1 true KR102885025B1 (ko) 2025-11-11

Family

ID=64661410

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207012736A Active KR102885025B1 (ko) 2017-11-03 2018-11-02 유전적 조절

Country Status (13)

Country Link
US (1) US11840737B2 (enExample)
EP (1) EP3704274B1 (enExample)
JP (2) JP2021501592A (enExample)
KR (1) KR102885025B1 (enExample)
CN (1) CN111511930B (enExample)
AU (1) AU2018361833B2 (enExample)
CA (1) CA3078675A1 (enExample)
ES (1) ES2987603T3 (enExample)
HU (1) HUE066292T2 (enExample)
MY (1) MY199800A (enExample)
PL (1) PL3704274T3 (enExample)
SG (1) SG11202003233YA (enExample)
WO (1) WO2019086898A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3152645A1 (en) * 2019-09-11 2021-03-18 Oxford BioDynamics PLC Diagnostic chromosome marker
EP4121964A1 (en) * 2020-03-17 2023-01-25 Regeneron Pharmaceuticals, Inc. Methods and systems for determining responders to treatment
GB202008269D0 (en) * 2020-06-02 2020-07-15 Oxford Biodynamics Ltd Detecting a chromosome marker
GB202016176D0 (en) * 2020-10-12 2020-11-25 Oxford BioDynamics PLC Disease marker
TW202302862A (zh) * 2021-03-04 2023-01-16 英商牛津生物力學公眾有限公司 染色體交互作用標記物
WO2025215189A1 (en) * 2024-04-12 2025-10-16 Oxford BioDynamics PLC Chromosome marker test

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016207653A1 (en) 2015-06-24 2016-12-29 Oxford Biodynamics Limited Detection of chromosome interactions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR036993A1 (es) * 2001-04-02 2004-10-20 Wyeth Corp Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas
GB0603251D0 (en) 2006-02-17 2006-03-29 Isis Innovation DNA conformation
AU2008204338B2 (en) 2007-01-11 2014-03-06 Erasmus University Medical Center Circular chromosome conformation capture (4C)
WO2009051268A2 (en) 2007-10-15 2009-04-23 Takeda Pharmaceutical Company Limited Preventive/remedy for cancer
GB0810051D0 (en) 2008-06-02 2008-07-09 Oxford Biodynamics Ltd Method of diagnosis
BRPI1007093A2 (pt) 2009-05-12 2017-06-06 Koninl Philips Electronics Nv fosfodiesterase 4d7 uso de pde4d7; composição metodo, metodo de aquisição de dados imunoensaio para detectar diagnosticar, monitorar ou prognosticar cancer de prostata ou para diagnosticar, detectar monitorar ou prognosticar progressao do cancer
EP3004877A4 (en) * 2013-06-06 2017-04-19 Dana-Farber Cancer Institute, Inc. Compositions and methods for identification, assessment prevention, and treatment of cancer using pd-l1 isoforms
WO2015077414A1 (en) 2013-11-20 2015-05-28 Dana-Farber Cancer Institute, Inc. Kynurenine pathway biomarkers predictive of anti-immune checkpoint inhibitor response

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016207653A1 (en) 2015-06-24 2016-12-29 Oxford Biodynamics Limited Detection of chromosome interactions
WO2016207661A1 (en) 2015-06-24 2016-12-29 Oxford Biodynamics Limited Detection processes using sites of chromosome interaction

Also Published As

Publication number Publication date
CA3078675A1 (en) 2019-05-09
AU2018361833A1 (en) 2020-04-30
AU2018361833B2 (en) 2021-04-22
EP3704274A2 (en) 2020-09-09
ES2987603T3 (es) 2024-11-15
SG11202003233YA (en) 2020-05-28
MY199800A (en) 2023-11-23
HUE066292T2 (hu) 2024-07-28
US20210230702A1 (en) 2021-07-29
EP3704274C0 (en) 2024-04-17
US11840737B2 (en) 2023-12-12
KR20200081380A (ko) 2020-07-07
JP2023082157A (ja) 2023-06-13
PL3704274T3 (pl) 2024-07-08
NZ763540A (en) 2025-03-28
WO2019086898A3 (en) 2019-06-13
WO2019086898A2 (en) 2019-05-09
JP2021501592A (ja) 2021-01-21
CN111511930B (zh) 2024-11-22
JP7631400B2 (ja) 2025-02-18
CN111511930A (zh) 2020-08-07
EP3704274B1 (en) 2024-04-17

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