JP2021501592A - 遺伝子調節 - Google Patents

遺伝子調節 Download PDF

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Publication number
JP2021501592A
JP2021501592A JP2020524490A JP2020524490A JP2021501592A JP 2021501592 A JP2021501592 A JP 2021501592A JP 2020524490 A JP2020524490 A JP 2020524490A JP 2020524490 A JP2020524490 A JP 2020524490A JP 2021501592 A JP2021501592 A JP 2021501592A
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Japan
Prior art keywords
chromosomal
interactions
nucleic acids
probe
chromosomal interactions
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Pending
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JP2020524490A
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English (en)
Japanese (ja)
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JP2021501592A5 (enExample
Inventor
アクーリチェフ、アレクサンドル
セルヴァム ラマダス、アロウル
セルヴァム ラマダス、アロウル
ハンター、ユアン
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Oxford Biodynamics PLC
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Oxford Biodynamics PLC
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Application filed by Oxford Biodynamics PLC filed Critical Oxford Biodynamics PLC
Publication of JP2021501592A publication Critical patent/JP2021501592A/ja
Publication of JP2021501592A5 publication Critical patent/JP2021501592A5/ja
Priority to JP2023060384A priority Critical patent/JP7631400B2/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020524490A 2017-11-03 2018-11-02 遺伝子調節 Pending JP2021501592A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023060384A JP7631400B2 (ja) 2017-11-03 2023-04-03 遺伝子調節

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762581287P 2017-11-03 2017-11-03
US62/581,287 2017-11-03
GBPCT/GB2018/052818 2018-10-03
GB2018052818 2018-10-03
PCT/GB2018/053196 WO2019086898A2 (en) 2017-11-03 2018-11-02 Genetic regulation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023060384A Division JP7631400B2 (ja) 2017-11-03 2023-04-03 遺伝子調節

Publications (2)

Publication Number Publication Date
JP2021501592A true JP2021501592A (ja) 2021-01-21
JP2021501592A5 JP2021501592A5 (enExample) 2021-12-09

Family

ID=64661410

Family Applications (2)

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JP2020524490A Pending JP2021501592A (ja) 2017-11-03 2018-11-02 遺伝子調節
JP2023060384A Active JP7631400B2 (ja) 2017-11-03 2023-04-03 遺伝子調節

Family Applications After (1)

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JP2023060384A Active JP7631400B2 (ja) 2017-11-03 2023-04-03 遺伝子調節

Country Status (13)

Country Link
US (1) US11840737B2 (enExample)
EP (1) EP3704274B1 (enExample)
JP (2) JP2021501592A (enExample)
KR (1) KR102885025B1 (enExample)
CN (1) CN111511930B (enExample)
AU (1) AU2018361833B2 (enExample)
CA (1) CA3078675A1 (enExample)
ES (1) ES2987603T3 (enExample)
HU (1) HUE066292T2 (enExample)
MY (1) MY199800A (enExample)
PL (1) PL3704274T3 (enExample)
SG (1) SG11202003233YA (enExample)
WO (1) WO2019086898A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024160217A (ja) * 2020-03-17 2024-11-13 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 治療に対するレスポンダを決定するための方法およびシステム

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3152645A1 (en) * 2019-09-11 2021-03-18 Oxford BioDynamics PLC Diagnostic chromosome marker
GB202008269D0 (en) * 2020-06-02 2020-07-15 Oxford Biodynamics Ltd Detecting a chromosome marker
GB202016176D0 (en) * 2020-10-12 2020-11-25 Oxford BioDynamics PLC Disease marker
TW202302862A (zh) * 2021-03-04 2023-01-16 英商牛津生物力學公眾有限公司 染色體交互作用標記物
WO2025215189A1 (en) * 2024-04-12 2025-10-16 Oxford BioDynamics PLC Chromosome marker test

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010515449A (ja) * 2007-01-11 2010-05-13 エラスムス ユニバーシティ メディカル センター 環状染色体コンホメーション捕捉(4c)
JP2011502108A (ja) * 2007-10-15 2011-01-20 武田薬品工業株式会社 癌の予防・治療剤
WO2016207661A1 (en) * 2015-06-24 2016-12-29 Oxford Biodynamics Limited Detection processes using sites of chromosome interaction
JP2017184729A (ja) * 2009-05-12 2017-10-12 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 前立腺癌マーカーとしてのホスホジエステラーゼ4d7

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR036993A1 (es) * 2001-04-02 2004-10-20 Wyeth Corp Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas
GB0603251D0 (en) 2006-02-17 2006-03-29 Isis Innovation DNA conformation
GB0810051D0 (en) 2008-06-02 2008-07-09 Oxford Biodynamics Ltd Method of diagnosis
EP3004877A4 (en) * 2013-06-06 2017-04-19 Dana-Farber Cancer Institute, Inc. Compositions and methods for identification, assessment prevention, and treatment of cancer using pd-l1 isoforms
WO2015077414A1 (en) 2013-11-20 2015-05-28 Dana-Farber Cancer Institute, Inc. Kynurenine pathway biomarkers predictive of anti-immune checkpoint inhibitor response

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010515449A (ja) * 2007-01-11 2010-05-13 エラスムス ユニバーシティ メディカル センター 環状染色体コンホメーション捕捉(4c)
JP2011502108A (ja) * 2007-10-15 2011-01-20 武田薬品工業株式会社 癌の予防・治療剤
JP2017184729A (ja) * 2009-05-12 2017-10-12 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 前立腺癌マーカーとしてのホスホジエステラーゼ4d7
WO2016207661A1 (en) * 2015-06-24 2016-12-29 Oxford Biodynamics Limited Detection processes using sites of chromosome interaction

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ALEXANDRE AKOULITCHEV ET AL.: "Pharmacogenetic 3C interaction associated with the PDGFRA gene as a chromatin conformation marker fo", JOURNAL OF CLINICAL ONCOLOGY, vol. Vol. 35、Issue 15, JPN6022042014, 30 May 2017 (2017-05-30), ISSN: 0005076715 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024160217A (ja) * 2020-03-17 2024-11-13 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 治療に対するレスポンダを決定するための方法およびシステム

Also Published As

Publication number Publication date
CA3078675A1 (en) 2019-05-09
AU2018361833A1 (en) 2020-04-30
AU2018361833B2 (en) 2021-04-22
EP3704274A2 (en) 2020-09-09
ES2987603T3 (es) 2024-11-15
SG11202003233YA (en) 2020-05-28
MY199800A (en) 2023-11-23
HUE066292T2 (hu) 2024-07-28
US20210230702A1 (en) 2021-07-29
EP3704274C0 (en) 2024-04-17
US11840737B2 (en) 2023-12-12
KR20200081380A (ko) 2020-07-07
JP2023082157A (ja) 2023-06-13
PL3704274T3 (pl) 2024-07-08
NZ763540A (en) 2025-03-28
KR102885025B1 (ko) 2025-11-11
WO2019086898A3 (en) 2019-06-13
WO2019086898A2 (en) 2019-05-09
CN111511930B (zh) 2024-11-22
JP7631400B2 (ja) 2025-02-18
CN111511930A (zh) 2020-08-07
EP3704274B1 (en) 2024-04-17

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