CA3078675A1 - Genetic regulation - Google Patents

Genetic regulation Download PDF

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Publication number
CA3078675A1
CA3078675A1 CA3078675A CA3078675A CA3078675A1 CA 3078675 A1 CA3078675 A1 CA 3078675A1 CA 3078675 A CA3078675 A CA 3078675A CA 3078675 A CA3078675 A CA 3078675A CA 3078675 A1 CA3078675 A1 CA 3078675A1
Authority
CA
Canada
Prior art keywords
chromosome
responder
interactions
nucleic acids
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3078675A
Other languages
English (en)
French (fr)
Inventor
Alexandre Akoulitchev
Aroul Selvam Ramadass
Ewan HUNTER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford Biodynamics PLC
Original Assignee
Oxford Biodynamics PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford Biodynamics PLC filed Critical Oxford Biodynamics PLC
Publication of CA3078675A1 publication Critical patent/CA3078675A1/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3078675A 2017-11-03 2018-11-02 Genetic regulation Pending CA3078675A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762581287P 2017-11-03 2017-11-03
US62/581,287 2017-11-03
GBPCT/GB2018/052818 2018-10-03
GB2018052818 2018-10-03
PCT/GB2018/053196 WO2019086898A2 (en) 2017-11-03 2018-11-02 Genetic regulation

Publications (1)

Publication Number Publication Date
CA3078675A1 true CA3078675A1 (en) 2019-05-09

Family

ID=64661410

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3078675A Pending CA3078675A1 (en) 2017-11-03 2018-11-02 Genetic regulation

Country Status (13)

Country Link
US (1) US11840737B2 (enExample)
EP (1) EP3704274B1 (enExample)
JP (2) JP2021501592A (enExample)
KR (1) KR102885025B1 (enExample)
CN (1) CN111511930B (enExample)
AU (1) AU2018361833B2 (enExample)
CA (1) CA3078675A1 (enExample)
ES (1) ES2987603T3 (enExample)
HU (1) HUE066292T2 (enExample)
MY (1) MY199800A (enExample)
PL (1) PL3704274T3 (enExample)
SG (1) SG11202003233YA (enExample)
WO (1) WO2019086898A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3152645A1 (en) * 2019-09-11 2021-03-18 Oxford BioDynamics PLC Diagnostic chromosome marker
EP4121964A1 (en) * 2020-03-17 2023-01-25 Regeneron Pharmaceuticals, Inc. Methods and systems for determining responders to treatment
GB202008269D0 (en) * 2020-06-02 2020-07-15 Oxford Biodynamics Ltd Detecting a chromosome marker
GB202016176D0 (en) * 2020-10-12 2020-11-25 Oxford BioDynamics PLC Disease marker
TW202302862A (zh) * 2021-03-04 2023-01-16 英商牛津生物力學公眾有限公司 染色體交互作用標記物
WO2025215189A1 (en) * 2024-04-12 2025-10-16 Oxford BioDynamics PLC Chromosome marker test

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR036993A1 (es) * 2001-04-02 2004-10-20 Wyeth Corp Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas
GB0603251D0 (en) 2006-02-17 2006-03-29 Isis Innovation DNA conformation
AU2008204338B2 (en) 2007-01-11 2014-03-06 Erasmus University Medical Center Circular chromosome conformation capture (4C)
WO2009051268A2 (en) 2007-10-15 2009-04-23 Takeda Pharmaceutical Company Limited Preventive/remedy for cancer
GB0810051D0 (en) 2008-06-02 2008-07-09 Oxford Biodynamics Ltd Method of diagnosis
BRPI1007093A2 (pt) 2009-05-12 2017-06-06 Koninl Philips Electronics Nv fosfodiesterase 4d7 uso de pde4d7; composição metodo, metodo de aquisição de dados imunoensaio para detectar diagnosticar, monitorar ou prognosticar cancer de prostata ou para diagnosticar, detectar monitorar ou prognosticar progressao do cancer
EP3004877A4 (en) * 2013-06-06 2017-04-19 Dana-Farber Cancer Institute, Inc. Compositions and methods for identification, assessment prevention, and treatment of cancer using pd-l1 isoforms
WO2015077414A1 (en) 2013-11-20 2015-05-28 Dana-Farber Cancer Institute, Inc. Kynurenine pathway biomarkers predictive of anti-immune checkpoint inhibitor response
JP2018518203A (ja) * 2015-06-24 2018-07-12 オックスフォード バイオダイナミックス リミテッド エピジェネティックな染色体相互作用

Also Published As

Publication number Publication date
AU2018361833A1 (en) 2020-04-30
AU2018361833B2 (en) 2021-04-22
EP3704274A2 (en) 2020-09-09
ES2987603T3 (es) 2024-11-15
SG11202003233YA (en) 2020-05-28
MY199800A (en) 2023-11-23
HUE066292T2 (hu) 2024-07-28
US20210230702A1 (en) 2021-07-29
EP3704274C0 (en) 2024-04-17
US11840737B2 (en) 2023-12-12
KR20200081380A (ko) 2020-07-07
JP2023082157A (ja) 2023-06-13
PL3704274T3 (pl) 2024-07-08
NZ763540A (en) 2025-03-28
KR102885025B1 (ko) 2025-11-11
WO2019086898A3 (en) 2019-06-13
WO2019086898A2 (en) 2019-05-09
JP2021501592A (ja) 2021-01-21
CN111511930B (zh) 2024-11-22
JP7631400B2 (ja) 2025-02-18
CN111511930A (zh) 2020-08-07
EP3704274B1 (en) 2024-04-17

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Effective date: 20231030