KR102763312B1 - 치료적으로 유효한 양의 재조합 aav9- 유도 벡터의 망막하 전달을 포함하는 대상체의 원추 광수용체 내 관심의 폴리뉴클레오티드를 발현하는 방법 - Google Patents
치료적으로 유효한 양의 재조합 aav9- 유도 벡터의 망막하 전달을 포함하는 대상체의 원추 광수용체 내 관심의 폴리뉴클레오티드를 발현하는 방법 Download PDFInfo
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| EP3606544B1 (en) | 2017-04-05 | 2025-06-04 | University of Massachusetts | Minigene therapy |
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| US20230159609A1 (en) * | 2020-04-10 | 2023-05-25 | Sorbonne Université | G-protein-gated-k+ channel-mediated enhancements in light sensitivity in rod-cone dystrophy (rcd) |
| CN113121655B (zh) * | 2021-04-19 | 2021-11-19 | 上海信致医药科技有限公司 | 眼部和肌肉特异靶向型腺相关病毒载体及其应用 |
| WO2022223644A2 (en) | 2021-04-20 | 2022-10-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Compositions and methods for treating retinal degenerative disorders |
| KR20240035759A (ko) * | 2021-05-26 | 2024-03-18 | 스페어링비젼 | 막대세포-원추세포 이상증(rcd)에서 g-단백질-개폐-k+ 채널-매개 감광성 향상 |
| WO2024084075A1 (en) | 2022-10-20 | 2024-04-25 | Sparingvision | Compositions and methods for treating retinal degenerative disorders |
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| US20150259395A1 (en) | 2014-03-17 | 2015-09-17 | Avalanche Biotechnologies, Inc. | Compositions and methods for enhanced gene expression in cone cells |
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| US6156303A (en) | 1997-06-11 | 2000-12-05 | University Of Washington | Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom |
| WO1999061601A2 (en) | 1998-05-28 | 1999-12-02 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Aav5 vector and uses thereof |
| DK1127150T3 (da) | 1998-11-05 | 2007-09-24 | Univ Pennsylvania | Nucleinsyresekvenser fra det adeno-associerede virus af serotype 1 samt vektorer og værtsceller, der indeholder disse |
| DE10216005A1 (de) | 2002-04-11 | 2003-10-30 | Max Planck Gesellschaft | Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle |
| EP3910063A1 (en) | 2003-09-30 | 2021-11-17 | The Trustees of The University of Pennsylvania | Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor |
| EP2465925A1 (en) | 2005-07-22 | 2012-06-20 | The Board Of Trustees Of The Leland | Light-activated cation channel and uses thereof |
| CA2685900A1 (en) | 2006-05-04 | 2007-11-15 | Wayne State University | Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids |
| EP2027889A1 (en) | 2007-06-05 | 2009-02-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | New neuronal viability factor and use thereof |
| US10266845B2 (en) * | 2013-02-08 | 2019-04-23 | The Trustees Of The University Of Pennsylvania | Enhanced AAV-mediated gene transfer for retinal therapies |
| IL289736B2 (en) | 2013-12-12 | 2025-09-01 | Massachusetts Inst Technology | Administration, use and therapeutic applications of CRISPR–Cas gene editing systems and gene editing preparations |
| EP3113787B1 (en) * | 2014-03-04 | 2019-12-04 | University of Florida Research Foundation, Inc. | Improved raav vectors and methods for transduction of photoreceptors and rpe cells |
| LT3137497T (lt) | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| ES2987090T3 (es) * | 2014-07-24 | 2024-11-13 | Massachusetts Eye & Ear Infirmary | Terapia génica con RPGR para retinitis pigmentosa |
| KR20170137730A (ko) * | 2015-03-02 | 2017-12-13 | 애드베룸 바이오테크놀로지스, 인코포레이티드 | 망막 추상체에 폴리뉴클레오타이드의 유리체 내 전달을 위한 조성물 및 방법 |
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| WO2018156654A1 (en) * | 2017-02-21 | 2018-08-30 | University Of Florida Research Foundation, Incorporated | Modified aav capsid proteins and uses thereof |
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| WO2012145601A2 (en) * | 2011-04-22 | 2012-10-26 | The Regents Of The University Of California | Adeno-associated virus virions with variant capsid and methods of use thereof |
| US20150259395A1 (en) | 2014-03-17 | 2015-09-17 | Avalanche Biotechnologies, Inc. | Compositions and methods for enhanced gene expression in cone cells |
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| JP7420710B2 (ja) | 2024-01-23 |
| US11723988B2 (en) | 2023-08-15 |
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| EP3697448A1 (en) | 2020-08-26 |
| CN111867635A (zh) | 2020-10-30 |
| US20210268125A1 (en) | 2021-09-02 |
| KR20200103634A (ko) | 2020-09-02 |
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