KR102733714B1 - 세포 집단의 증대를 위한 방법 및 조성물 - Google Patents

세포 집단의 증대를 위한 방법 및 조성물 Download PDF

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KR102733714B1
KR102733714B1 KR1020207013360A KR20207013360A KR102733714B1 KR 102733714 B1 KR102733714 B1 KR 102733714B1 KR 1020207013360 A KR1020207013360 A KR 1020207013360A KR 20207013360 A KR20207013360 A KR 20207013360A KR 102733714 B1 KR102733714 B1 KR 102733714B1
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전뤼 리
펑쉬 첸
린헝 리
촨 허
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스토워스 인스티튜트 포 메디컬 리서치
유니버시티 오브 시카고
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
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    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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KR1020207013360A 2017-10-09 2018-10-09 세포 집단의 증대를 위한 방법 및 조성물 Active KR102733714B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762570076P 2017-10-09 2017-10-09
US62/570,076 2017-10-09
US201862695820P 2018-07-09 2018-07-09
US62/695,820 2018-07-09
PCT/US2018/055092 WO2019074980A1 (en) 2017-10-09 2018-10-09 METHODS AND COMPOSITIONS FOR EXPANSION OF CELL POPULATION

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KR20200078536A KR20200078536A (ko) 2020-07-01
KR102733714B1 true KR102733714B1 (ko) 2024-11-26

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US (1) US12359200B2 (enExample)
EP (1) EP3694533A4 (enExample)
JP (2) JP2020536554A (enExample)
KR (1) KR102733714B1 (enExample)
CN (2) CN120366217A (enExample)
WO (1) WO2019074980A1 (enExample)

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US11046969B2 (en) 2017-05-24 2021-06-29 Epiplanta Biotech Ltd. Transgenic plant and the method for producing the same
JP2020536554A (ja) 2017-10-09 2020-12-17 ストワーズ インスティテュート フォー メディカル リサーチ 細胞集団を増大させるための方法および組成物
WO2021003330A1 (en) * 2019-07-03 2021-01-07 Children's Medical Center Corporation Inhibiting the rna methyltransferase mettl3 or its interaction with eif3h to suppress oncogene translation and tumorigenesis
CN115884781A (zh) * 2020-06-09 2023-03-31 杭州领知医药科技有限公司 用于增强免疫应答的组合物和方法
EP4178586A4 (en) * 2020-07-09 2024-10-09 Shanghai Institute of Materia Medica, Chinese Academy of Sciences Compositions and methods for inhibiting ythdf1
WO2022055971A1 (en) * 2020-09-09 2022-03-17 Duke University Methods for reprogramming target cells
US20230383292A1 (en) * 2020-10-19 2023-11-30 The General Hospital Corporation Targeting xist and rna methylation for x reactivation therapy
CN112941102A (zh) * 2021-01-26 2021-06-11 南方医科大学 一种子痫前期小鼠动物模型的构建方法及其应用
CN112941105A (zh) * 2021-02-08 2021-06-11 江西农业大学 一种m6A“阅读器”YTHDF2基因改造方法及其应用
CN112899238B (zh) * 2021-04-01 2023-09-26 中国药科大学 基于RNA-m6A修饰水平的化合物筛选细胞模型及其构建与应用
WO2022241165A2 (en) * 2021-05-12 2022-11-17 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods of use for mutated hotair in the treatment of cancers
CN116024326A (zh) * 2022-09-21 2023-04-28 安徽中医药大学第一附属医院(安徽省中医院) 类风湿关节炎m6A甲基化修饰基因PTEN的应用及其检测方法
CN115463155B (zh) * 2022-11-01 2023-05-23 卡瑞济(北京)生命科技有限公司 间充质干细胞的用途
WO2024151006A1 (ko) * 2023-01-09 2024-07-18 한국생명공학연구원 Fto 유전자의 발현이 억제된 줄기세포 및 이로부터 분화된 면역세포
KR20260007568A (ko) * 2023-03-31 2026-01-14 주식회사 바이오오케스트라 Mirna-484 억제제 및 이의 용도
WO2025117708A2 (en) * 2023-11-28 2025-06-05 Baruch S. Blumberg Institute Method and system for use of mutant mrna in liquid biopsies to risk stratify and manage cancer

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WO2012027376A2 (en) 2010-08-23 2012-03-01 The Research Foundation Of State University Of New York Method for expansion of stem cells and the use of such cells
US20160264934A1 (en) * 2015-03-11 2016-09-15 The General Hospital Corporation METHODS FOR MODULATING AND ASSAYING m6A IN STEM CELL POPULATIONS

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WO2012027376A2 (en) 2010-08-23 2012-03-01 The Research Foundation Of State University Of New York Method for expansion of stem cells and the use of such cells
US20160264934A1 (en) * 2015-03-11 2016-09-15 The General Hospital Corporation METHODS FOR MODULATING AND ASSAYING m6A IN STEM CELL POPULATIONS

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JP2020536554A (ja) 2020-12-17
CN111511376A (zh) 2020-08-07
CN111511376B (zh) 2025-02-25
US20200370044A1 (en) 2020-11-26
KR20200078536A (ko) 2020-07-01
WO2019074980A1 (en) 2019-04-18
CN120366217A (zh) 2025-07-25
EP3694533A1 (en) 2020-08-19
JP2023171952A (ja) 2023-12-05
US12359200B2 (en) 2025-07-15
EP3694533A4 (en) 2021-07-14

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