KR102694809B1 - Pnpla3 i148m 변이를 발현하는 환자의 간 질환의 치료에서의 hsd17b13의 저해 - Google Patents

Pnpla3 i148m 변이를 발현하는 환자의 간 질환의 치료에서의 hsd17b13의 저해 Download PDF

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KR102694809B1
KR102694809B1 KR1020207013128A KR20207013128A KR102694809B1 KR 102694809 B1 KR102694809 B1 KR 102694809B1 KR 1020207013128 A KR1020207013128 A KR 1020207013128A KR 20207013128 A KR20207013128 A KR 20207013128A KR 102694809 B1 KR102694809 B1 KR 102694809B1
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seq
hsd17b13
protein
nucleic acid
acid sequence
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KR20200062314A (ko
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여롱 신
제스퍼 그로마다
시핑 쳉
프레드릭 드웨이
탄야 테슬로비취 도스탈
클라우디아 스커르만
아리스 바라스
노우라 애불-허슨
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리제너론 파마슈티칼스 인코포레이티드
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KR1020207013128A 2017-10-11 2018-10-11 Pnpla3 i148m 변이를 발현하는 환자의 간 질환의 치료에서의 hsd17b13의 저해 Active KR102694809B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247026391A KR20240125690A (ko) 2017-10-11 2018-10-11 Pnpla3 i148m 변이를 발현하는 환자의 간 질환의 치료에서의 hsd17b13의 저해

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762570985P 2017-10-11 2017-10-11
US62/570,985 2017-10-11
PCT/US2018/055377 WO2019075181A1 (en) 2017-10-11 2018-10-11 INHIBITION OF HSD17B13 IN THE TREATMENT OF HEPATIC DISEASE IN PATIENTS EXPRESSING PNPLA3 I148M VARIATION

Related Child Applications (1)

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KR1020247026391A Division KR20240125690A (ko) 2017-10-11 2018-10-11 Pnpla3 i148m 변이를 발현하는 환자의 간 질환의 치료에서의 hsd17b13의 저해

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KR20200062314A KR20200062314A (ko) 2020-06-03
KR102694809B1 true KR102694809B1 (ko) 2024-08-16

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KR1020247026391A Pending KR20240125690A (ko) 2017-10-11 2018-10-11 Pnpla3 i148m 변이를 발현하는 환자의 간 질환의 치료에서의 hsd17b13의 저해
KR1020207013128A Active KR102694809B1 (ko) 2017-10-11 2018-10-11 Pnpla3 i148m 변이를 발현하는 환자의 간 질환의 치료에서의 hsd17b13의 저해

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US (4) US10961583B2 (enExample)
EP (2) EP4234719B1 (enExample)
JP (2) JP7434151B2 (enExample)
KR (2) KR20240125690A (enExample)
CN (1) CN111183234A (enExample)
AU (2) AU2018348195B2 (enExample)
CA (1) CA3078883A1 (enExample)
IL (2) IL273550B2 (enExample)
MX (1) MX2020003561A (enExample)
RU (1) RU2020115526A (enExample)
SG (1) SG11202003254SA (enExample)
WO (1) WO2019075181A1 (enExample)

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KR20230124915A (ko) * 2020-12-23 2023-08-28 리제너론 파마슈티칼스 인코포레이티드 세포 사멸 유도 dffa 유사 이펙터 b(cideb) 억제제를 이용한 간 질환의 치료
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CN114262738B (zh) * 2021-12-31 2023-03-31 吉林大学第一医院 Hsd17b13基因多态性在中重度mafld诊断中的应用
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WO2025098440A1 (zh) * 2023-11-08 2025-05-15 浙江扬厉医药技术有限公司 抑制PNPLA3表达的双链siRNA以及其缀合物
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