KR102660005B1 - 유로리틴 화합물을 포함하는 조성물 - Google Patents

유로리틴 화합물을 포함하는 조성물 Download PDF

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Publication number
KR102660005B1
KR102660005B1 KR1020187007291A KR20187007291A KR102660005B1 KR 102660005 B1 KR102660005 B1 KR 102660005B1 KR 1020187007291 A KR1020187007291 A KR 1020187007291A KR 20187007291 A KR20187007291 A KR 20187007291A KR 102660005 B1 KR102660005 B1 KR 102660005B1
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composition
urolithin
muscle
medium
chain triglycerides
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Korean (ko)
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KR20180037052A (ko
Inventor
페넬로페 안드레욱
크리스토퍼 린슈
빌리엄 블랑코-보제
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아마젠티스 에스에이
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Publication of KR20180037052A publication Critical patent/KR20180037052A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020187007291A 2015-08-28 2016-08-26 유로리틴 화합물을 포함하는 조성물 Active KR102660005B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247012842A KR102822365B1 (ko) 2015-08-28 2016-08-26 유로리틴 화합물을 포함하는 조성물

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1515387.7 2015-08-28
GBGB1515387.7A GB201515387D0 (en) 2015-08-28 2015-08-28 Compositions
PCT/EP2016/070255 WO2017036992A1 (en) 2015-08-28 2016-08-26 Compositions comprising urolithin compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020247012842A Division KR102822365B1 (ko) 2015-08-28 2016-08-26 유로리틴 화합물을 포함하는 조성물

Publications (2)

Publication Number Publication Date
KR20180037052A KR20180037052A (ko) 2018-04-10
KR102660005B1 true KR102660005B1 (ko) 2024-04-22

Family

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KR1020187007291A Active KR102660005B1 (ko) 2015-08-28 2016-08-26 유로리틴 화합물을 포함하는 조성물
KR1020247012842A Active KR102822365B1 (ko) 2015-08-28 2016-08-26 유로리틴 화합물을 포함하는 조성물

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Country Status (15)

Country Link
US (4) US10695320B2 (enExample)
EP (1) EP3340977B1 (enExample)
JP (3) JP7227003B2 (enExample)
KR (2) KR102660005B1 (enExample)
CN (1) CN108289879A (enExample)
AU (1) AU2016314987B2 (enExample)
BR (1) BR112018003745B1 (enExample)
CA (1) CA2996724C (enExample)
ES (1) ES2936723T3 (enExample)
GB (1) GB201515387D0 (enExample)
MX (1) MX2018002543A (enExample)
PT (1) PT3340977T (enExample)
RU (1) RU2754761C2 (enExample)
SG (1) SG10202001793PA (enExample)
WO (1) WO2017036992A1 (enExample)

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GB201515387D0 (en) * 2015-08-28 2015-10-14 Amazentis Sa Compositions
WO2018162650A1 (en) * 2017-03-08 2018-09-13 Amazentis Sa Methods for improving mitophagy in subjects
CN112638889A (zh) 2018-05-15 2021-04-09 路易斯维尔大学研究基金会 用于治疗的尿石素a和其衍生物
GB201916046D0 (en) * 2019-11-04 2019-12-18 Amazentis Sa Diagnostic method
CA3188397A1 (en) 2020-09-25 2022-03-31 Anupama Dattatreya Compositions and methods using xanthan gum to stabilize at least one urolithin in an aqueous matrix
JP7541673B2 (ja) * 2020-11-30 2024-08-29 国立研究開発法人産業技術総合研究所 筋ジストロフィーの抗炎症剤、筋ジストロフィーにおける抗炎症のための中心静脈栄養用組成物および筋ジストロフィーの抗炎症用食品組成物
KR102623664B1 (ko) 2020-12-10 2024-01-12 서울대학교산학협력단 유로리틴 a를 이용한 당뇨성 알츠하이머병의 치료 조성물 및 치료 방법
AU2022212883A1 (en) 2021-01-27 2023-08-17 Vandria Sa Urolithin derivatives and methods of use thereof
EP4085906A1 (en) * 2021-05-06 2022-11-09 Universite De Bordeaux Composition comprising ppar-modulator and an urolithin derivative and uses thereof
CN113813255B (zh) * 2021-10-20 2023-09-01 山东大学 尿石素a及其衍生物在肿瘤免疫治疗的应用
JPWO2023199908A1 (enExample) * 2022-04-11 2023-10-19
GB202219317D0 (en) * 2022-12-20 2023-02-01 Amazentis Sa Methods for improving mitophagy in subjects
WO2024142098A1 (en) * 2022-12-27 2024-07-04 Indian Institute Of Science A method for the treatment of epilepsy
GB202316295D0 (en) 2023-10-24 2023-12-06 Amazentis Sa Composition
EP4555997A1 (en) * 2023-11-15 2025-05-21 Science4Beauty Sp. z o.o. Water-soluble composition comprising urolithin
GB202319994D0 (en) 2023-12-22 2024-02-07 Amazentis Sa Compositions for use
KR20250158913A (ko) 2024-04-30 2025-11-07 주식회사 파이안바이오테크놀로지 유로리틴을 함유하는 탈모완화제와 모발성장촉진제
WO2025252771A1 (en) 2024-06-03 2025-12-11 Amazentis Sa Urolithin combinations

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Also Published As

Publication number Publication date
KR20180037052A (ko) 2018-04-10
JP2018533618A (ja) 2018-11-15
JP7227003B2 (ja) 2023-02-21
BR112018003745B1 (pt) 2023-11-07
JP2022177130A (ja) 2022-11-30
CN108289879A (zh) 2018-07-17
EP3340977A1 (en) 2018-07-04
US20180243261A1 (en) 2018-08-30
US20200323818A1 (en) 2020-10-15
RU2018108136A (ru) 2019-09-30
SG10202001793PA (en) 2020-04-29
KR102822365B1 (ko) 2025-06-17
US20220323407A1 (en) 2022-10-13
KR20240060826A (ko) 2024-05-08
AU2016314987A1 (en) 2018-03-29
AU2016314987B2 (en) 2021-07-08
GB201515387D0 (en) 2015-10-14
PT3340977T (pt) 2023-01-31
WO2017036992A1 (en) 2017-03-09
HK1257500A1 (en) 2019-10-25
EP3340977B1 (en) 2022-11-02
RU2754761C2 (ru) 2021-09-07
JP2025004129A (ja) 2025-01-14
CA2996724A1 (en) 2017-03-09
CA2996724C (en) 2024-05-21
US11925616B2 (en) 2024-03-12
US20240148690A1 (en) 2024-05-09
MX2018002543A (es) 2018-06-15
ES2936723T3 (es) 2023-03-21
US11337957B2 (en) 2022-05-24
RU2018108136A3 (enExample) 2020-01-31
US10695320B2 (en) 2020-06-30
BR112018003745A2 (pt) 2018-09-25

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