KR102643280B1 - 변형된 인자 h 결합 단백질 - Google Patents

변형된 인자 h 결합 단백질 Download PDF

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KR102643280B1
KR102643280B1 KR1020197008694A KR20197008694A KR102643280B1 KR 102643280 B1 KR102643280 B1 KR 102643280B1 KR 1020197008694 A KR1020197008694 A KR 1020197008694A KR 20197008694 A KR20197008694 A KR 20197008694A KR 102643280 B1 KR102643280 B1 KR 102643280B1
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KR20190064577A (ko
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크리스토프 엠 탕
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옥스포드 유니버시티 이노베이션 리미티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020197008694A 2016-08-31 2017-08-31 변형된 인자 h 결합 단백질 Active KR102643280B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1614687.0 2016-08-31
GBGB1614687.0A GB201614687D0 (en) 2016-08-31 2016-08-31 fHbp scaffold
PCT/GB2017/052535 WO2018042178A1 (en) 2016-08-31 2017-08-31 Modified factor h binding protein

Publications (2)

Publication Number Publication Date
KR20190064577A KR20190064577A (ko) 2019-06-10
KR102643280B1 true KR102643280B1 (ko) 2024-03-05

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KR1020197008694A Active KR102643280B1 (ko) 2016-08-31 2017-08-31 변형된 인자 h 결합 단백질

Country Status (13)

Country Link
US (1) US12497432B2 (cg-RX-API-DMAC7.html)
EP (1) EP3506934A1 (cg-RX-API-DMAC7.html)
JP (1) JP7525093B2 (cg-RX-API-DMAC7.html)
KR (1) KR102643280B1 (cg-RX-API-DMAC7.html)
CN (1) CN109890412B (cg-RX-API-DMAC7.html)
AU (1) AU2017319218B2 (cg-RX-API-DMAC7.html)
BR (1) BR112019003957A2 (cg-RX-API-DMAC7.html)
CA (1) CA3035159A1 (cg-RX-API-DMAC7.html)
GB (2) GB201614687D0 (cg-RX-API-DMAC7.html)
IL (1) IL265078B2 (cg-RX-API-DMAC7.html)
MX (1) MX420767B (cg-RX-API-DMAC7.html)
WO (1) WO2018042178A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201901862B (cg-RX-API-DMAC7.html)

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* Cited by examiner, † Cited by third party
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GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
CN110903400A (zh) * 2019-11-08 2020-03-24 苏州微超生物科技有限公司 B群脑膜炎球菌fHBP多变体融合蛋白及其制备方法与应用
CN111533792B (zh) * 2020-07-07 2020-10-16 康希诺生物股份公司 一种定点突变的载体蛋白及其在制备疫苗中的用途
WO2022071291A1 (ja) * 2020-09-29 2022-04-07 出光興産株式会社 ペプチドタグおよびそれを含むタグ付加タンパク質
IN202321021121A (cg-RX-API-DMAC7.html) * 2023-03-24 2024-04-19

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ATE492288T1 (de) * 2002-10-11 2011-01-15 Novartis Vaccines & Diagnostic Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien
GB0227346D0 (en) * 2002-11-22 2002-12-31 Chiron Spa 741
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CN102302776B (zh) * 2003-01-30 2014-06-18 诺华疫苗和诊断有限公司 抗多种脑膜炎球菌血清组的可注射性疫苗
CN103405761A (zh) * 2003-10-02 2013-11-27 诺华疫苗和诊断有限公司 多种脑膜炎球菌血清群的液体疫苗
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WO2006024954A2 (en) 2004-09-01 2006-03-09 Novartis Vaccines And Diagnostics Srl Domains and epitopes of meningococcal protein nmb1870
WO2007060548A2 (en) * 2005-11-25 2007-05-31 Novartis Vaccines And Diagnostics Srl Chimeric, hybrid and tandem polypeptides of meningococcal nmb1870
WO2016083583A1 (en) * 2014-11-28 2016-06-02 Crucell Holland B.V. Meningitis b vaccine

Also Published As

Publication number Publication date
JP7525093B2 (ja) 2024-07-30
CN109890412A (zh) 2019-06-14
IL265078A (cg-RX-API-DMAC7.html) 2019-04-30
IL265078B1 (en) 2023-04-01
GB2568440B (en) 2022-08-17
AU2017319218A2 (en) 2019-05-02
GB201614687D0 (en) 2016-10-12
AU2017319218A1 (en) 2019-04-18
GB2568440A (en) 2019-05-15
GB201903866D0 (en) 2019-05-08
AU2017319218B2 (en) 2021-10-28
JP2019526261A (ja) 2019-09-19
BR112019003957A2 (pt) 2019-06-25
CN109890412B (zh) 2025-04-04
WO2018042178A1 (en) 2018-03-08
KR20190064577A (ko) 2019-06-10
IL265078B2 (en) 2023-08-01
MX2019002248A (es) 2019-09-18
US12497432B2 (en) 2025-12-16
MX420767B (es) 2025-02-10
CA3035159A1 (en) 2018-03-08
NZ751995A (en) 2024-03-22
EP3506934A1 (en) 2019-07-10
US20220112249A1 (en) 2022-04-14
ZA201901862B (en) 2020-09-30

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