KR102634491B1 - 이식가능한 약물 전달 조성물 및 이들의 이용 방법 - Google Patents
이식가능한 약물 전달 조성물 및 이들의 이용 방법 Download PDFInfo
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- KR102634491B1 KR102634491B1 KR1020177035884A KR20177035884A KR102634491B1 KR 102634491 B1 KR102634491 B1 KR 102634491B1 KR 1020177035884 A KR1020177035884 A KR 1020177035884A KR 20177035884 A KR20177035884 A KR 20177035884A KR 102634491 B1 KR102634491 B1 KR 102634491B1
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Botany (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polymers & Plastics (AREA)
- Epoxy Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562181707P | 2015-06-18 | 2015-06-18 | |
| US62/181,707 | 2015-06-18 | ||
| PCT/US2016/038080 WO2016205652A1 (en) | 2015-06-18 | 2016-06-17 | Implantable drug delivery compositions and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20180019555A KR20180019555A (ko) | 2018-02-26 |
| KR102634491B1 true KR102634491B1 (ko) | 2024-02-07 |
Family
ID=57546385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177035884A Active KR102634491B1 (ko) | 2015-06-18 | 2016-06-17 | 이식가능한 약물 전달 조성물 및 이들의 이용 방법 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10888530B2 (enExample) |
| EP (1) | EP3310343B1 (enExample) |
| JP (2) | JP6869902B2 (enExample) |
| KR (1) | KR102634491B1 (enExample) |
| CN (2) | CN117442742A (enExample) |
| AU (1) | AU2016280274B2 (enExample) |
| BR (1) | BR112017026746B1 (enExample) |
| CA (1) | CA2989171A1 (enExample) |
| IL (2) | IL287749B2 (enExample) |
| MX (2) | MX382255B (enExample) |
| RU (1) | RU2739033C2 (enExample) |
| SG (1) | SG10202103998RA (enExample) |
| WO (1) | WO2016205652A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10842485B2 (en) | 2009-10-15 | 2020-11-24 | Covidien Lp | Brachytherapy buttress |
| US20150231409A1 (en) | 2009-10-15 | 2015-08-20 | Covidien Lp | Buttress brachytherapy and integrated staple line markers for margin identification |
| US10874768B2 (en) * | 2017-01-20 | 2020-12-29 | Covidien Lp | Drug eluting medical device |
| CN110603076A (zh) | 2017-05-11 | 2019-12-20 | 阿尔法陶医疗有限公司 | 用于近距离放射治疗装置的聚合物涂层 |
| RU2020130217A (ru) * | 2018-04-02 | 2022-05-04 | Альфа Тау Медикал Лтд. | Контролируемое высвобождение радионуклидов |
| WO2019226519A1 (en) | 2018-05-24 | 2019-11-28 | Celanese EVA Performance Polymers Corporation | Implantable device for sustained release of a macromolecular drug compound |
| WO2019222856A1 (en) | 2018-05-24 | 2019-11-28 | Nureva Inc. | Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones |
| EP3801462A4 (en) | 2018-05-24 | 2022-03-16 | Celanese EVA Performance Polymers LLC | Implantable device for sustained release of a macromolecular drug compound |
| AU2019362880B2 (en) * | 2018-10-16 | 2025-05-22 | Research Triangle Institute | Subcutaneous biodegradable reservoir device |
| CN109908108B (zh) * | 2019-03-15 | 2022-05-03 | 深圳市光远生物材料有限责任公司 | 一种载药纳米复合纤维膜系统及其制备方法和应用 |
| US11596403B2 (en) * | 2019-05-08 | 2023-03-07 | Covidien Lp | Surgical stapling device |
| US20200352565A1 (en) * | 2019-05-08 | 2020-11-12 | Covidien Lp | Surgical stapling device |
| US11478245B2 (en) * | 2019-05-08 | 2022-10-25 | Covidien Lp | Surgical stapling device |
| CN114053249B (zh) * | 2020-08-10 | 2023-06-02 | 山东百多安医疗器械股份有限公司 | 一种可治疗全身骨质疏松的可降解载药薄膜及其制备工艺 |
| AU2021400142B2 (en) | 2020-12-16 | 2024-11-21 | Alpha Tau Medical Ltd. | Diffusing alpha-emitters radiation therapy with enhanced beta treatment |
| JP2024515220A (ja) | 2021-04-26 | 2024-04-05 | セラニーズ・イーブイエイ・パフォーマンス・ポリマーズ・エルエルシー | 高分子薬剤化合物の持続放出用の埋め込み型デバイス |
| CN113289075B (zh) * | 2021-04-28 | 2022-09-30 | 珠海横乐医学科技有限公司 | 一种可降解的组合物及其制备方法和应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070299542A1 (en) | 2006-06-22 | 2007-12-27 | Radi Medical Systems Ab | Mesh implant for use in reconstruction of soft tissue defects |
| US20100278725A1 (en) * | 2005-08-12 | 2010-11-04 | Jiang Liu | Methods and devices for lymphatic targeting |
| US20110172785A1 (en) * | 2008-05-13 | 2011-07-14 | The Trustees Of Boston University | Compliant composites for application of drug-eluting coatings to tissue surfaces |
| US20130281977A1 (en) * | 2010-12-30 | 2013-10-24 | Nanyang Technological University | Device for controlled release of a bioactive agent |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992011843A1 (en) * | 1991-01-09 | 1992-07-23 | Alza Corporation | Bioerodible devices and compositions for diffusional release of agents |
| AU2007254682B2 (en) | 1993-07-19 | 2011-06-02 | Angiotech Pharmaceuticals, Inc. | Anti-angiogenic compositions and methods of use |
| NZ268326A (en) | 1993-07-19 | 1997-12-19 | Angiogenesis Tech Inc | Stent with a coating comprising an anti-angiogenic compound, such as taxol, and a polymeric carrier |
| US5994341A (en) | 1993-07-19 | 1999-11-30 | Angiogenesis Technologies, Inc. | Anti-angiogenic Compositions and methods for the treatment of arthritis |
| US5626862A (en) | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
| US5759583A (en) * | 1995-08-30 | 1998-06-02 | Syntex (U.S.A.) Inc. | Sustained release poly (lactic/glycolic) matrices |
| US6110484A (en) * | 1998-11-24 | 2000-08-29 | Cohesion Technologies, Inc. | Collagen-polymer matrices with differential biodegradability |
| AU779277B2 (en) * | 1999-06-04 | 2005-01-13 | Alza Corporation | Implantable gel compositions and method of manufacture |
| KR100446101B1 (ko) * | 2000-12-07 | 2004-08-30 | 주식회사 삼양사 | 수난용성 약물의 서방성 제형 조성물 |
| US20030203000A1 (en) * | 2002-04-24 | 2003-10-30 | Schwarz Marlene C. | Modulation of therapeutic agent release from a polymeric carrier using solvent-based techniques |
| DK1638624T3 (da) * | 2003-06-19 | 2014-02-03 | Vascular Therapies Llc | Vaskulær lukkeindretning |
| US7531503B2 (en) * | 2005-03-11 | 2009-05-12 | Wake Forest University Health Sciences | Cell scaffold matrices with incorporated therapeutic agents |
| US10029034B2 (en) | 2005-12-15 | 2018-07-24 | CARDINAL HEALTH SWITZERLAND 515 GmbH | Drug-eluting articles with improved drug release profiles |
| CN101091806A (zh) * | 2006-06-20 | 2007-12-26 | 天津市凯迪亚医疗器械有限公司 | 冠脉支架可降解药物缓释涂层 |
| ITMI20061539A1 (it) * | 2006-08-02 | 2008-02-03 | Mediolanum Pharmaceuticals Ltd | Impianti sottocutanei in grado di rilasciare il principio attivo per un periodo prolungato di tempo |
| US8709071B1 (en) * | 2007-09-28 | 2014-04-29 | Abbott Cardiovascular Systems Inc. | Stent with preferential coating |
| CN101147814A (zh) * | 2007-11-16 | 2008-03-26 | 蔡绪旺 | 一种血管药物支架 |
| CN101264346A (zh) * | 2007-11-27 | 2008-09-17 | 天津百畅医疗器械科技有限公司 | 含有抗凝血磷酸胆碱成份的可降解聚合物血管支架药物涂层 |
| US8629172B2 (en) * | 2008-04-18 | 2014-01-14 | Warsaw Orthopedic, Inc. | Methods and compositions for treating post-operative pain comprising clonidine |
| US20100249924A1 (en) * | 2009-03-27 | 2010-09-30 | Allergan, Inc. | Bioerodible matrix for tissue involvement |
| WO2011064773A1 (en) * | 2009-11-24 | 2011-06-03 | Collplant Ltd. | Method of generating collagen fibers |
| EP2900289A1 (en) * | 2012-09-28 | 2015-08-05 | Allergan, Inc. | Porogen compositions, methods of making and uses |
| US9707322B2 (en) * | 2012-12-21 | 2017-07-18 | University Of Connecticut | Gradient porous scaffolds |
| US10682415B2 (en) * | 2013-07-22 | 2020-06-16 | Wisconsin Alumni Research Foundation | Thermogel formulation for combination drug delivery |
-
2016
- 2016-06-17 CA CA2989171A patent/CA2989171A1/en active Pending
- 2016-06-17 CN CN202311411716.6A patent/CN117442742A/zh active Pending
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- 2016-06-17 IL IL287749A patent/IL287749B2/en unknown
- 2016-06-17 WO PCT/US2016/038080 patent/WO2016205652A1/en not_active Ceased
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-
2021
- 2021-04-14 JP JP2021068064A patent/JP2021107420A/ja active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100278725A1 (en) * | 2005-08-12 | 2010-11-04 | Jiang Liu | Methods and devices for lymphatic targeting |
| US20070299542A1 (en) | 2006-06-22 | 2007-12-27 | Radi Medical Systems Ab | Mesh implant for use in reconstruction of soft tissue defects |
| US20110172785A1 (en) * | 2008-05-13 | 2011-07-14 | The Trustees Of Boston University | Compliant composites for application of drug-eluting coatings to tissue surfaces |
| US20130281977A1 (en) * | 2010-12-30 | 2013-10-24 | Nanyang Technological University | Device for controlled release of a bioactive agent |
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| BR112017026746A2 (pt) | 2018-08-28 |
| JP2018524310A (ja) | 2018-08-30 |
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| US20180193282A1 (en) | 2018-07-12 |
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| BR112017026746B1 (pt) | 2023-11-28 |
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