KR102630689B1 - 호기 및 에어로졸 분석을 이용한 호흡기 질환 진단 - Google Patents

호기 및 에어로졸 분석을 이용한 호흡기 질환 진단 Download PDF

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KR102630689B1
KR102630689B1 KR1020227035599A KR20227035599A KR102630689B1 KR 102630689 B1 KR102630689 B1 KR 102630689B1 KR 1020227035599 A KR1020227035599 A KR 1020227035599A KR 20227035599 A KR20227035599 A KR 20227035599A KR 102630689 B1 KR102630689 B1 KR 102630689B1
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sample
breath
packed bed
capture element
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KR20230005825A (ko
Inventor
다펭 첸
웨인 에이 브라이든
마이클 맥러린
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제테오 테크, 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G01N33/4975—Physical analysis of biological material of gaseous biological material, e.g. breath other than oxygen, carbon dioxide or alcohol, e.g. organic vapours
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B2010/0083—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements for taking gas samples
    • A61B2010/0087—Breath samples
    • G01N2033/4975—

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
KR1020227035599A 2020-04-03 2020-08-26 호기 및 에어로졸 분석을 이용한 호흡기 질환 진단 Active KR102630689B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247001565A KR102746174B1 (ko) 2020-04-03 2020-08-26 호기 및 에어로졸 분석을 이용한 호흡기 질환 진단

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063005179P 2020-04-03 2020-04-03
US63/005,179 2020-04-03
US202063010029P 2020-04-14 2020-04-14
US63/010,029 2020-04-14
US202063069029P 2020-08-22 2020-08-22
US63/069,029 2020-08-22
PCT/US2020/048035 WO2021201905A1 (en) 2020-04-03 2020-08-26 Diagnosis of respiratory diseases using analysis of exhaled breath and aerosols

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020247001565A Division KR102746174B1 (ko) 2020-04-03 2020-08-26 호기 및 에어로졸 분석을 이용한 호흡기 질환 진단

Publications (2)

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KR20230005825A KR20230005825A (ko) 2023-01-10
KR102630689B1 true KR102630689B1 (ko) 2024-01-29

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KR1020227035599A Active KR102630689B1 (ko) 2020-04-03 2020-08-26 호기 및 에어로졸 분석을 이용한 호흡기 질환 진단
KR1020247041584A Pending KR20250004143A (ko) 2020-04-03 2020-08-26 호기 및 에어로졸 분석을 이용한 호흡기 질환 진단
KR1020247001565A Active KR102746174B1 (ko) 2020-04-03 2020-08-26 호기 및 에어로졸 분석을 이용한 호흡기 질환 진단

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KR1020247001565A Active KR102746174B1 (ko) 2020-04-03 2020-08-26 호기 및 에어로졸 분석을 이용한 호흡기 질환 진단

Country Status (6)

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US (1) US11839463B2 (enExample)
EP (1) EP4125569B1 (enExample)
JP (2) JP7504499B2 (enExample)
KR (3) KR102630689B1 (enExample)
WO (1) WO2021201905A1 (enExample)
ZA (2) ZA202211682B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102816565B1 (ko) 2024-12-31 2025-06-04 주식회사 지엠디바이오텍 공기 중 바이러스에 대한 액체 샘플 생성 장치
KR102816566B1 (ko) 2024-12-31 2025-06-04 주식회사 지엠디바이오텍 공기 중 바이러스 검출 장치
KR20250153943A (ko) 2024-04-18 2025-10-28 주식회사 에이아이더뉴트리진 독감, rsv, 결핵 등 호흡기 감염병을 포함한 다중 진단용 페이퍼 기반 원스텝 올인원 분자진단 키트

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102485642B1 (ko) 2019-08-26 2023-01-06 제테오 테크, 인코포레이티드 호기를 이용한 결핵 및 기타 질병의 진단
US12074018B2 (en) 2019-09-23 2024-08-27 Zeteo Tech, Inc. Systems and methods of rapid and autonomous detection of aerosol particles
WO2021061330A1 (en) 2019-09-23 2021-04-01 Zeteo Tech, Inc. Systems and methods of rapid and autonomous detection of aerosol particles
EP4125569B1 (en) 2020-04-03 2026-05-20 Zeteo Tech Inc SYSTEM FOR DIAGNOSING RESPIRATORY DISEASES USING ANALYSIS OF EXHAUSTED AIR AND AEROSOLS
WO2024249186A1 (en) * 2023-05-26 2024-12-05 Zeteo Tech, Inc. Systems and methods for capturing aerosolized biomaterial particles using packed beds
US12364411B2 (en) 2020-04-03 2025-07-22 Zeteo Tech, Inc. Diagnosis of respiratory diseases using analysis of exhaled breath and aerosols
IT202000028022A1 (it) * 2020-11-23 2022-05-23 Spectra 2000 Srl Dispositivo per la raccolta dell’esalato
US20240003917A1 (en) * 2021-03-10 2024-01-04 Richard Postrel Non Invasive Device for Early Stage Alzheimer's and Neurodegenerative Disease Detection
US20220386893A1 (en) * 2021-03-31 2022-12-08 Zeteo Tech Inc. Capturing truncated proteoforms in exhaled breath for diagnosis and treatment of diseases
JP2024518022A (ja) 2021-03-31 2024-04-24 ゼテオ テック、 インク． 充填ベッドシステムおよび方法を使用したエアロゾル化生体材料粒子の捕捉による呼吸器疾患の診断
GB202110582D0 (en) * 2021-07-22 2021-09-08 Owlstone Med Ltd Breath sampling device
CN114199861B (zh) * 2021-11-24 2024-04-26 中国汽车技术研究中心有限公司 检测低浓度含水气体的电子鼻及方法
CN114343723B (zh) * 2021-12-22 2022-11-22 北京华泰诺安技术有限公司 非侵入式同时收集人体呼出气溶胶与气体的系统及方法
CN114533037B (zh) * 2022-02-23 2022-11-22 安徽省立医院(中国科学技术大学附属第一医院) 一种基于儿童呼吸气体的疾病检测系统及方法
AU2023253642A1 (en) * 2022-04-15 2024-10-24 Washington University Systems and methods for airborne environmental detection and surveillance of pathogens with electrochemical analysis
DE102022204390A1 (de) * 2022-05-04 2023-11-09 Robert Bosch Gesellschaft mit beschränkter Haftung Vorrichtung und Verfahren zum Sammeln von Atemluftkondensat
SE547329C2 (en) * 2022-06-03 2025-07-01 Munkplast Ab Method and system for preparing a breath sample for analysis
CN115326986A (zh) * 2022-08-29 2022-11-11 浙江大学 一种测定人体呼出气中有机酸和阴离子的分析装置及方法
US12276586B2 (en) * 2022-11-30 2025-04-15 Breath Of Health Ltd. Method and system for detecting non-volatile and semi-volatile organic compounds in mid-ir spectrometry gas cell configurations
WO2025090670A1 (en) * 2023-10-27 2025-05-01 Zeteo Tech, Inc. Capturing truncated proteoforms in exhaled breath
WO2025202679A1 (en) * 2024-03-26 2025-10-02 Rs Dynamics Medical Gmbh System and method for capturing chemical constituents from air samples
WO2025226796A1 (en) * 2024-04-24 2025-10-30 Purdue Research Foundation Surface extraction system and method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170035326A1 (en) * 2015-08-09 2017-02-09 Elemental Sensor Llc Device for capturing and concentrating volatile organic compounds

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0989863A (ja) 1995-09-25 1997-04-04 Suzuki Motor Corp 呼気分析装置
JPH09126958A (ja) 1995-10-30 1997-05-16 Suzuki Motor Corp 呼気採取装置
JPH10227725A (ja) * 1997-02-12 1998-08-25 Suzuki Motor Corp 呼気分析装置
US6267016B1 (en) 1999-03-10 2001-07-31 Mesosystems Technology, Inc. Impact particulate collector using a rotary impeller for collecting particulates and moving a fluid
US6062392A (en) 1998-11-13 2000-05-16 Mesosystems Technology, Inc. Micromachined virtual impactor
US7364553B2 (en) 2002-12-20 2008-04-29 Amidex, Inc. Breath aerosol management and collection system
EP1627223A1 (en) 2003-04-01 2006-02-22 The Charles Stark Draper Laboratory, INC. Non-invasive breath analysis using field asymmetric ion mobility spectrometry
US8627821B2 (en) 2005-01-10 2014-01-14 Pulmatrix, Inc. Method and device for decreasing contamination
JP4564406B2 (ja) * 2005-05-25 2010-10-20 株式会社日立製作所 呼気捕集フィルタ、呼気収集装置、呼気分析システムおよび呼気分析方法
EP2194867B1 (en) 2007-10-02 2021-06-02 Anna-Carin Olin Collection and measurement of exhaled particles
EP2060919A1 (en) 2007-11-13 2009-05-20 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO MALDI matrix and MALDI method
US10568541B2 (en) 2008-12-01 2020-02-25 TricornTech Taiwan Breath analysis systems and methods for asthma, tuberculosis and lung cancer diagnostics and disease management
CA2771830C (en) 2009-09-09 2019-02-26 Sensa Bues Ab Drug detection in exhaled breath
JP5652847B2 (ja) * 2009-11-10 2015-01-14 公益財団法人北九州産業学術推進機構 呼気分析の方法
CN103119417B (zh) 2010-07-06 2016-08-03 戴顿公司 空气传播的细菌样品收集和分析系统
US20120172679A1 (en) 2010-12-30 2012-07-05 Logan Robert J Systems and methods for monitoring and processing biometric data
US10359417B2 (en) * 2012-03-08 2019-07-23 Sensa Bues Ab Portable sampling device and method for detection of biomarkers in exhaled breath
JP2016512431A (ja) 2013-03-12 2016-04-28 デトン コーポレイション 呼吸サンプルの収集および分析のためのシステム
US10307080B2 (en) 2014-03-07 2019-06-04 Spirosure, Inc. Respiratory monitor
KR20160009740A (ko) 2014-07-16 2016-01-27 연세대학교 산학협력단 말디톱 질량분석기에 이용가능한 시료 플레이트 및 상기 시료 플레이트의 제조방법, 그리고 상기 시료 플레이트를 이용한 질량분석 방법
JP6530141B2 (ja) 2015-08-24 2019-06-12 ゼテオ テック、 エルエルシイＺｅｔｅｏ Ｔｅｃｈ， Ｌｌｃ 音響コータを用いたエアロゾル粒子のコーティング
EP3143930A1 (en) 2015-09-21 2017-03-22 Université de Liège Method for the diagnosis of airway disease inflammatory subtype
US10502665B2 (en) * 2016-04-18 2019-12-10 University Of Maryland, College Park Aerosol collection system and method
WO2017187120A1 (en) * 2016-04-25 2017-11-02 Owlstone Medical Limited Systems and device for capturing breath samples
WO2017197386A1 (en) 2016-05-13 2017-11-16 The Brigham And Women's Hospital, Inc. Volatile metabolite profiles for the diagnosis and treatment of mucorales fungi
ES2969976T3 (es) 2016-11-07 2024-05-23 Ausmed Global Ltd Monitoreo no invasivo de la diabetes mediante sensores fotónicos
JP6967198B2 (ja) * 2017-05-18 2021-11-17 東海光学株式会社 呼気ミスト捕集装置、呼気ミスト分析システム、呼気ミスト捕集方法及び呼気ミスト分析方法
SE541748C2 (en) * 2017-07-10 2019-12-10 Pexa Ab System for collecting exhaled particles
GB201801153D0 (en) 2018-01-24 2018-03-07 Owlstone Med Ltd Apparatus and method for obtaining a breath sample
JP2019184288A (ja) 2018-04-03 2019-10-24 国立研究開発法人量子科学技術研究開発機構 気体分析装置及びこの装置に適用するマスク
WO2021061330A1 (en) 2019-09-23 2021-04-01 Zeteo Tech, Inc. Systems and methods of rapid and autonomous detection of aerosol particles
EP4125569B1 (en) 2020-04-03 2026-05-20 Zeteo Tech Inc SYSTEM FOR DIAGNOSING RESPIRATORY DISEASES USING ANALYSIS OF EXHAUSTED AIR AND AEROSOLS
US12533047B2 (en) 2020-04-19 2026-01-27 John J. Daniels Mask-based diagnostic system using exhaled breath condensate

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170035326A1 (en) * 2015-08-09 2017-02-09 Elemental Sensor Llc Device for capturing and concentrating volatile organic compounds

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250153943A (ko) 2024-04-18 2025-10-28 주식회사 에이아이더뉴트리진 독감, rsv, 결핵 등 호흡기 감염병을 포함한 다중 진단용 페이퍼 기반 원스텝 올인원 분자진단 키트
KR102816565B1 (ko) 2024-12-31 2025-06-04 주식회사 지엠디바이오텍 공기 중 바이러스에 대한 액체 샘플 생성 장치
KR102816566B1 (ko) 2024-12-31 2025-06-04 주식회사 지엠디바이오텍 공기 중 바이러스 검출 장치

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Publication number Publication date
KR20240013274A (ko) 2024-01-30
US20230157573A1 (en) 2023-05-25
JP7504499B2 (ja) 2024-06-24
EP4125569B1 (en) 2026-05-20
ZA202211682B (en) 2024-10-30
ZA202400813B (en) 2024-06-26
KR20250004143A (ko) 2025-01-07
WO2021201905A1 (en) 2021-10-07
US11839463B2 (en) 2023-12-12
KR20230005825A (ko) 2023-01-10
JP2023528725A (ja) 2023-07-06
EP4125569A4 (en) 2024-03-13
EP4125569A1 (en) 2023-02-08
KR102746174B1 (ko) 2024-12-23
JP7855248B2 (ja) 2026-05-08
JP2024116220A (ja) 2024-08-27

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