KR102610930B1 - 3-클로로-N-[트랜스-4-(메틸아미노)사이클로헥실]-N-[[3-(4-피리디닐)페닐]메틸]벤조[b]티오펜-2-카복사마이드를 포함하는 피부 미백용 조성물 - Google Patents

3-클로로-N-[트랜스-4-(메틸아미노)사이클로헥실]-N-[[3-(4-피리디닐)페닐]메틸]벤조[b]티오펜-2-카복사마이드를 포함하는 피부 미백용 조성물 Download PDF

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Publication number
KR102610930B1
KR102610930B1 KR1020160107873A KR20160107873A KR102610930B1 KR 102610930 B1 KR102610930 B1 KR 102610930B1 KR 1020160107873 A KR1020160107873 A KR 1020160107873A KR 20160107873 A KR20160107873 A KR 20160107873A KR 102610930 B1 KR102610930 B1 KR 102610930B1
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South Korea
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composition
trans
pyridinyl
methylamino
benzo
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Korean (ko)
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KR20180022439A (ko
Inventor
최현정
배일홍
김형준
이영진
이태룡
조동형
Original Assignee
(주)아모레퍼시픽
경희대학교 산학협력단
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Priority to KR1020160107873A priority Critical patent/KR102610930B1/ko
Priority to CN201780066049.9A priority patent/CN109890383B/zh
Priority to JP2019506499A priority patent/JP6883090B2/ja
Priority to PCT/KR2017/009033 priority patent/WO2018038465A1/ko
Publication of KR20180022439A publication Critical patent/KR20180022439A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Cosmetics (AREA)
KR1020160107873A 2016-08-24 2016-08-24 3-클로로-N-[트랜스-4-(메틸아미노)사이클로헥실]-N-[[3-(4-피리디닐)페닐]메틸]벤조[b]티오펜-2-카복사마이드를 포함하는 피부 미백용 조성물 Active KR102610930B1 (ko)

Priority Applications (4)

Application Number Priority Date Filing Date Title
KR1020160107873A KR102610930B1 (ko) 2016-08-24 2016-08-24 3-클로로-N-[트랜스-4-(메틸아미노)사이클로헥실]-N-[[3-(4-피리디닐)페닐]메틸]벤조[b]티오펜-2-카복사마이드를 포함하는 피부 미백용 조성물
CN201780066049.9A CN109890383B (zh) 2016-08-24 2017-08-18 用于皮肤美白的组合物
JP2019506499A JP6883090B2 (ja) 2016-08-24 2017-08-18 ３−クロロ−Ｎ−［トランス−４−（メチルアミノ）シクロヘキシル］−Ｎ−［［３−（４−ピリジニル）フェニル］メチル］ベンゾ［ｂ］チオフェン−２−カルボキサミドを含む皮膚美白用組成物
PCT/KR2017/009033 WO2018038465A1 (ko) 2016-08-24 2017-08-18 3-클로로-N-[트랜스-4-(메틸아미노)사이클로헥실]-N-[[3-(4-피리디닐)페닐]메틸]벤조[b]티오펜-2-카복사마이드를 포함하는 피부 미백용 조성물

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020160107873A KR102610930B1 (ko) 2016-08-24 2016-08-24 3-클로로-N-[트랜스-4-(메틸아미노)사이클로헥실]-N-[[3-(4-피리디닐)페닐]메틸]벤조[b]티오펜-2-카복사마이드를 포함하는 피부 미백용 조성물

Publications (2)

Publication Number Publication Date
KR20180022439A KR20180022439A (ko) 2018-03-06
KR102610930B1 true KR102610930B1 (ko) 2023-12-08

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KR1020160107873A Active KR102610930B1 (ko) 2016-08-24 2016-08-24 3-클로로-N-[트랜스-4-(메틸아미노)사이클로헥실]-N-[[3-(4-피리디닐)페닐]메틸]벤조[b]티오펜-2-카복사마이드를 포함하는 피부 미백용 조성물

Country Status (4)

Country Link
JP (1) JP6883090B2 (https=)
KR (1) KR102610930B1 (https=)
CN (1) CN109890383B (https=)
WO (1) WO2018038465A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11300683B2 (en) 2016-12-30 2022-04-12 Innovusion Ireland Limited Multiwavelength LiDAR design
KR102511934B1 (ko) * 2021-04-27 2023-03-21 재단법인 아산사회복지재단 피부 색소침착의 예방, 개선, 또는 치료용 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100422290C (zh) * 2003-09-10 2008-10-01 株式会社资生堂 抗氧剂、美白剂以及配合其的皮肤外用剂
CN101597280B (zh) * 2008-08-19 2013-06-05 北京大学深圳研究生院 用作七次穿膜蛋白抑制剂的基于sag结构的化合物
JP2013523721A (ja) * 2010-03-31 2013-06-17 株式會社アモーレパシフィック メラニン色素生成抑制剤及びこれを含有する化粧料組成物
CN101993415B (zh) * 2010-09-15 2013-08-14 北京韩美药品有限公司 作为Hedgehog通路抑制剂的化合物以及包含该化合物的药物组合物及其应用
CN102731373B (zh) * 2012-07-19 2013-11-27 南京药石药物研发有限公司 抗肿瘤药物gdc-0449中间体的制备方法
WO2014084085A1 (ja) * 2012-11-28 2014-06-05 国立大学法人名古屋大学 聴覚障害又は小脳性運動失調症の予防・治療剤
KR101480600B1 (ko) * 2013-01-22 2015-01-08 경북대학교 산학협력단 레스베라트롤 유도체의 피부미백 용도
KR101628282B1 (ko) * 2013-07-12 2016-06-08 주식회사 바이오랜드 알부틴 유도체를 함유하는 피부 미백용 조성물
GB2519344A (en) * 2013-10-18 2015-04-22 Redx Pharma Ltd Compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Journal of Investigative Dermatology Volume 125, Issue 4, October 2005, Pages 638-646

Also Published As

Publication number Publication date
JP6883090B2 (ja) 2021-06-09
KR20180022439A (ko) 2018-03-06
WO2018038465A1 (ko) 2018-03-01
CN109890383A (zh) 2019-06-14
CN109890383B (zh) 2022-06-07
JP2019526545A (ja) 2019-09-19

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