KR102502745B1 - 고형종양 진단을 위한 바이오마커 절대 정량 방법 및 장치 - Google Patents

고형종양 진단을 위한 바이오마커 절대 정량 방법 및 장치 Download PDF

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KR102502745B1
KR102502745B1 KR1020207002341A KR20207002341A KR102502745B1 KR 102502745 B1 KR102502745 B1 KR 102502745B1 KR 1020207002341 A KR1020207002341 A KR 1020207002341A KR 20207002341 A KR20207002341 A KR 20207002341A KR 102502745 B1 KR102502745 B1 KR 102502745B1
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옌타이 콴티시젼 다이애그노틱스 인크.
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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KR1020207002341A 2017-06-29 2018-06-28 고형종양 진단을 위한 바이오마커 절대 정량 방법 및 장치 Active KR102502745B1 (ko)

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US201762526425P 2017-06-29 2017-06-29
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PCT/US2018/040075 WO2019006156A1 (en) 2017-06-29 2018-06-28 APPARATUS AND METHOD FOR ABSOLUTE QUANTIFICATION OF BIOMARKERS FOR SOLID TUMOR DIAGNOSIS

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Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX357763B (es) 2013-10-18 2018-07-23 Univ Health Network Tratamiento para cancer pancreatico.
SG11201808629UA (en) * 2016-04-21 2018-11-29 Immatics Biotechnologies Gmbh Immunotherapy against melanoma and other cancers
DE102016209871A1 (de) 2016-06-06 2017-12-07 Robert Bosch Gmbh Stanzvorrichtung und Verfahren zum Stanzen eines Lumens und Implantieren einer Implantateinrichtung
DE102018201030B4 (de) * 2018-01-24 2025-10-16 Kardion Gmbh Magnetkuppelelement mit magnetischer Lagerungsfunktion
DE102018206750A1 (de) 2018-05-02 2019-11-07 Kardion Gmbh Vorrichtung zur induktiven Energieübertragung in einen menschlichen Körper und deren Verwendung
DE102018206754A1 (de) 2018-05-02 2019-11-07 Kardion Gmbh Verfahren und Vorrichtung zur Bestimmung der Temperatur an einer Oberfläche sowie Verwendung des Verfahrens
DE102018206725A1 (de) 2018-05-02 2019-11-07 Kardion Gmbh Empfangseinheit, Sendeeinheit, Energieübertragungssystem und Verfahren zur drahtlosen Energieübertragung
DE102018206727A1 (de) 2018-05-02 2019-11-07 Kardion Gmbh Energieübertragungssystem und Empfangseinheit zur drahtlosen transkutanen Energieübertragung
DE102018206724A1 (de) 2018-05-02 2019-11-07 Kardion Gmbh Energieübertragungssystem und Verfahren zur drahtlosen Energieübertragung
DE102018206731A1 (de) 2018-05-02 2019-11-07 Kardion Gmbh Vorrichtung zur induktiven Energieübertragung in einen menschlichen Körper und Verwendung der Vorrichtung
DE102018207611A1 (de) 2018-05-16 2019-11-21 Kardion Gmbh Rotorlagerungssystem
DE102018207575A1 (de) 2018-05-16 2019-11-21 Kardion Gmbh Magnetische Stirndreh-Kupplung zur Übertragung von Drehmomenten
DE102018208539A1 (de) 2018-05-30 2019-12-05 Kardion Gmbh Motorgehäusemodul zum Abdichten eines Motorraums eines Motors eines Herzunterstützungssystems und Herzunterstützungssystem und Verfahren zum Montieren eines Herzunterstützungssystems
DE102018208538A1 (de) 2018-05-30 2019-12-05 Kardion Gmbh Intravasale Blutpumpe und Verfahren zur Herstellung von elektrischen Leiterbahnen
DE102018208541A1 (de) 2018-05-30 2019-12-05 Kardion Gmbh Axialpumpe für ein Herzunterstützungssystem und Verfahren zum Herstellen einer Axialpumpe für ein Herzunterstützungssystem
DE102018208549A1 (de) 2018-05-30 2019-12-05 Kardion Gmbh Elektronikmodul für ein Herzunterstützungssystem und Verfahren zum Herstellen eines Elektronikmoduls für ein Herzunterstützungssystem
DE102018208550A1 (de) 2018-05-30 2019-12-05 Kardion Gmbh Leitungsvorrichtung zum Leiten eines Blutstroms für ein Herzunterstützungssystem, Herzunterstützungssystem und Verfahren zum Herstellen einer Leitungsvorrichtung
DE102018208555A1 (de) 2018-05-30 2019-12-05 Kardion Gmbh Vorrichtung zum Verankern eines Herzunterstützungssystems in einem Blutgefäß, Verfahren zum Betreiben und Herstellverfahren zum Herstellen einer Vorrichtung und Herzunterstützungssystem
DE102018210076A1 (de) 2018-06-21 2019-12-24 Kardion Gmbh Verfahren und Vorrichtung zum Erkennen eines Verschleißzustands eines Herzunterstützungssystems, Verfahren und Vorrichtung zum Betreiben eines Herzunterstützungssystems und Herzunterstützungssystem
DE102018210058A1 (de) 2018-06-21 2019-12-24 Kardion Gmbh Statorschaufelvorrichtung zur Strömungsführung eines aus einer Austrittsöffnung eines Herzunterstützungssystems ausströmenden Fluids, Herzunterstützungssystem mit Statorschaufelvorrichtung, Verfahren zum Betreiben einer Statorschaufelvorrichtung und Herstellverfahren
EP3818496A4 (en) * 2018-07-02 2022-04-20 Tempus Labs, Inc. 3D RADIOMICS PLATFORM FOR IMAGING BIOMARKER DEVELOPMENT
DE102018211297A1 (de) 2018-07-09 2020-01-09 Kardion Gmbh Herzunterstützungssystem und Verfahren zur Überwachung der Integrität einer Haltestruktur eines Herzunterstützungssystems
DE102018211327A1 (de) 2018-07-10 2020-01-16 Kardion Gmbh Laufrad für ein implantierbares, vaskuläres Unterstützungssystem
DE102018211328A1 (de) 2018-07-10 2020-01-16 Kardion Gmbh Laufradgehäuse für ein implantierbares, vaskuläres Unterstützungssystem
DE102018212153A1 (de) 2018-07-20 2020-01-23 Kardion Gmbh Zulaufleitung für eine Pumpeneinheit eines Herzunterstützungssystems, Herzunterstützungssystem und Verfahren zum Herstellen einer Zulaufleitung für eine Pumpeneinheit eines Herzunterstützungssystems
AU2019320533B2 (en) 2018-08-07 2024-11-21 Kardion Gmbh Bearing device for a cardiac support system, and method for flushing an intermediate space in a bearing device for a cardiac support system
CN114631027A (zh) * 2019-11-01 2022-06-14 烟台康体诊医疗科技有限公司 基于定量生物标志物的癌症诊断方法及其数据库
AU2021207312A1 (en) * 2020-01-17 2022-06-30 Universität Zürich Single cell pathology analysis of tumour samples
DE102020102474A1 (de) 2020-01-31 2021-08-05 Kardion Gmbh Pumpe zum Fördern eines Fluids und Verfahren zum Herstellen einer Pumpe
US11699551B2 (en) 2020-11-05 2023-07-11 Kardion Gmbh Device for inductive energy transmission in a human body and use of the device

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140227372A1 (en) 2011-05-25 2014-08-14 Novartis Ag Biomarkers for lung cancer

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003252235A1 (en) * 2002-07-25 2004-02-16 Ajinomoto Co., Inc. Method of analyzing protein
DE60200248T2 (de) * 2002-08-01 2005-01-27 Mtm Laboratories Ag Verfahren für Lösung-basierte Diagnose
DE102005023011A1 (de) * 2005-05-19 2006-11-23 Qiagen Gmbh Quantitative Proteinbestimmung von Formalin fixiertem Gewebe
CA2653398A1 (en) * 2006-05-26 2007-12-06 Board Of Regents, The University Of Texas System Reverse phase protein array, protein activation and expression signatures, and associated methods
GB0611669D0 (en) * 2006-06-13 2006-07-19 Astrazeneca Uk Ltd Mass spectrometry biomarker assay
JPWO2008075664A1 (ja) * 2006-12-21 2010-04-15 味の素株式会社 癌の評価方法、ならびに癌評価装置、癌評価方法、癌評価システム、癌評価プログラムおよび記録媒体
US8771962B2 (en) * 2008-10-02 2014-07-08 Sarka O. Southern Health test for a broad spectrum of health problems
EP2239675A1 (en) 2009-04-07 2010-10-13 BIOCRATES Life Sciences AG Method for in vitro diagnosing a complex disease
JP2013099253A (ja) * 2010-03-11 2013-05-23 Intec Systems Institute Inc 肺癌または子宮頸癌の診断マーカー
US8293487B1 (en) * 2012-01-06 2012-10-23 Jiandi Zhang Zestern, a simple, fast, specific and quantifiable improvement of immunodetection process
WO2016172216A1 (en) * 2015-04-20 2016-10-27 The Methodist Hospital Use of soluble crkl compositions as breast cancer biomarkers and predictors of cancer metastasis
US9933418B2 (en) * 2015-05-26 2018-04-03 Quanticision Diagnostics Inc. Multi-unit plate for electroblotting and immunoblot analysis
IL294138A (en) * 2015-05-29 2022-08-01 Genentech Inc Therapeutic and diagnostic methods for cancer
EP3465200A4 (en) * 2016-06-05 2020-07-08 Berg LLC PATIENT STRATIFICATION SYSTEMS AND METHODS AND IDENTIFICATION OF POTENTIAL BIOMARKERS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140227372A1 (en) 2011-05-25 2014-08-14 Novartis Ag Biomarkers for lung cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Guillemin et al., Journal of Physiology and Pharmacology, Vol. 60, Suppl. 3, 2009, pp. 91-97.
Venugopal et al., Clinical Proteomics, Vol. 10, No. 3, 2013.

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CA3101968A1 (en) 2019-01-03
KR20200020906A (ko) 2020-02-26
US20190004037A1 (en) 2019-01-03
SG11201908865WA (en) 2019-10-30
EP3646328A4 (en) 2021-04-21
JP7194128B2 (ja) 2022-12-21
EP3646328A1 (en) 2020-05-06
US20210011010A1 (en) 2021-01-14
JP2020526747A (ja) 2020-08-31
CN110753845A (zh) 2020-02-04
WO2019006156A1 (en) 2019-01-03
US10788484B2 (en) 2020-09-29
CN110753845B (zh) 2023-08-22

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