KR102410503B1 - 안구 장애를 치료하기 위한 옥시메타졸린 조성물 및 방법 - Google Patents

안구 장애를 치료하기 위한 옥시메타졸린 조성물 및 방법 Download PDF

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KR102410503B1
KR102410503B1 KR1020200050837A KR20200050837A KR102410503B1 KR 102410503 B1 KR102410503 B1 KR 102410503B1 KR 1020200050837 A KR1020200050837 A KR 1020200050837A KR 20200050837 A KR20200050837 A KR 20200050837A KR 102410503 B1 KR102410503 B1 KR 102410503B1
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KR20200128629A (ko
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티나 드브리스
데이비드 제이콥스
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알브이엘 파마슈티컬즈, 인크.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020200050837A 2019-05-06 2020-04-27 안구 장애를 치료하기 위한 옥시메타졸린 조성물 및 방법 Active KR102410503B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020220072209A KR102663319B1 (ko) 2019-05-06 2022-06-14 안구 장애를 치료하기 위한 옥시메타졸린 조성물 및 방법

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201962843819P 2019-05-06 2019-05-06
US201962844069P 2019-05-06 2019-05-06
US62/843,819 2019-05-06
US62/844,069 2019-05-06
US16/715,998 2019-12-16
US16/716,014 US10799481B1 (en) 2019-05-06 2019-12-16 Compositions and methods for treating ocular disorders
US16/716,014 2019-12-16
US16/715,998 US10814001B1 (en) 2019-05-06 2019-12-16 Oxymetazoline compositions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020220072209A Division KR102663319B1 (ko) 2019-05-06 2022-06-14 안구 장애를 치료하기 위한 옥시메타졸린 조성물 및 방법

Publications (2)

Publication Number Publication Date
KR20200128629A KR20200128629A (ko) 2020-11-16
KR102410503B1 true KR102410503B1 (ko) 2022-06-17

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Application Number Title Priority Date Filing Date
KR1020200050837A Active KR102410503B1 (ko) 2019-05-06 2020-04-27 안구 장애를 치료하기 위한 옥시메타졸린 조성물 및 방법
KR1020220072209A Active KR102663319B1 (ko) 2019-05-06 2022-06-14 안구 장애를 치료하기 위한 옥시메타졸린 조성물 및 방법
KR1020240057166A Active KR102859351B1 (ko) 2019-05-06 2024-04-29 안구 장애를 치료하기 위한 옥시메타졸린 조성물 및 방법

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Application Number Title Priority Date Filing Date
KR1020220072209A Active KR102663319B1 (ko) 2019-05-06 2022-06-14 안구 장애를 치료하기 위한 옥시메타졸린 조성물 및 방법
KR1020240057166A Active KR102859351B1 (ko) 2019-05-06 2024-04-29 안구 장애를 치료하기 위한 옥시메타졸린 조성물 및 방법

Country Status (16)

Country Link
US (11) US10814001B1 (enExample)
EP (1) EP3965737A1 (enExample)
JP (3) JP7141420B2 (enExample)
KR (3) KR102410503B1 (enExample)
CN (2) CN117045596A (enExample)
AU (1) AU2020268329B2 (enExample)
BR (1) BR112021022404A2 (enExample)
CL (1) CL2021002918A1 (enExample)
CO (1) CO2021015265A2 (enExample)
IL (1) IL287831A (enExample)
MA (1) MA55895A (enExample)
MX (1) MX429190B (enExample)
PE (1) PE20220384A1 (enExample)
SG (1) SG11202112272TA (enExample)
WO (1) WO2020227260A1 (enExample)
ZA (2) ZA202108950B (enExample)

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US10814001B1 (en) * 2019-05-06 2020-10-27 Rvl Pharmaceuticals, Inc. Oxymetazoline compositions
WO2022187306A1 (en) 2021-03-03 2022-09-09 Voom, Llc Compositions and methods for treatment of blepharitis
WO2023079427A1 (en) * 2021-11-03 2023-05-11 Avaca Pharma Private Limited Ophthalmic compositions and methods thereof

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WO2010141831A1 (en) * 2009-06-05 2010-12-09 Aciex Therapeutics, Inc. Ophthalmic formulations, methods of manufacture, and methods of using same

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Publication number Publication date
US20210137889A1 (en) 2021-05-13
CN111888326A (zh) 2020-11-06
US11103482B2 (en) 2021-08-31
US10898573B1 (en) 2021-01-26
EP3965737A1 (en) 2022-03-16
JP2020183373A (ja) 2020-11-12
CN111888326B (zh) 2023-07-21
US12605363B2 (en) 2026-04-21
US11311515B2 (en) 2022-04-26
JP7141420B2 (ja) 2022-09-22
US20220273621A1 (en) 2022-09-01
US10799481B1 (en) 2020-10-13
US10940138B2 (en) 2021-03-09
US20210015795A1 (en) 2021-01-21
JP2025065198A (ja) 2025-04-17
KR102663319B1 (ko) 2024-05-03
NZ782902A (en) 2024-09-27
ZA202108950B (en) 2023-10-25
CL2021002918A1 (es) 2022-08-19
US20210212992A1 (en) 2021-07-15
CO2021015265A2 (es) 2022-02-28
PE20220384A1 (es) 2022-03-18
KR20220084264A (ko) 2022-06-21
US20220257566A1 (en) 2022-08-18
CN117045596A (zh) 2023-11-14
ZA202212328B (en) 2025-03-26
US10814001B1 (en) 2020-10-27
IL287831A (en) 2022-01-01
US20200353083A1 (en) 2020-11-12
MX2021013516A (es) 2022-01-24
US20210386711A1 (en) 2021-12-16
US12648930B2 (en) 2026-06-09
SG11202112272TA (en) 2021-12-30
CA3139443A1 (en) 2020-11-12
KR20200128629A (ko) 2020-11-16
US20210023222A1 (en) 2021-01-28
MA55895A (fr) 2022-03-16
KR102859351B1 (ko) 2025-09-12
US11701343B2 (en) 2023-07-18
US20230355587A1 (en) 2023-11-09
AU2020268329A1 (en) 2022-01-06
MX429190B (es) 2025-11-13
AU2020268329B2 (en) 2026-01-15
KR20240060580A (ko) 2024-05-08
JP2021191802A (ja) 2021-12-16
JP7705326B2 (ja) 2025-07-09
US11541036B2 (en) 2023-01-03
BR112021022404A2 (pt) 2022-01-18
US11324722B2 (en) 2022-05-10
WO2020227260A1 (en) 2020-11-12
US20240033250A1 (en) 2024-02-01

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