KR102407053B1 - 갑상선 베타-작용제의 사용 - Google Patents
갑상선 베타-작용제의 사용 Download PDFInfo
- Publication number
- KR102407053B1 KR102407053B1 KR1020187033321A KR20187033321A KR102407053B1 KR 102407053 B1 KR102407053 B1 KR 102407053B1 KR 1020187033321 A KR1020187033321 A KR 1020187033321A KR 20187033321 A KR20187033321 A KR 20187033321A KR 102407053 B1 KR102407053 B1 KR 102407053B1
- Authority
- KR
- South Korea
- Prior art keywords
- group
- alkyl
- compound
- optionally substituted
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662326431P | 2016-04-22 | 2016-04-22 | |
| US62/326,431 | 2016-04-22 | ||
| PCT/US2017/029102 WO2017185083A1 (en) | 2016-04-22 | 2017-04-24 | Use of thyroid beta-agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20190017748A KR20190017748A (ko) | 2019-02-20 |
| KR102407053B1 true KR102407053B1 (ko) | 2022-06-10 |
Family
ID=60117062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187033321A Active KR102407053B1 (ko) | 2016-04-22 | 2017-04-24 | 갑상선 베타-작용제의 사용 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20190134069A1 (https=) |
| EP (1) | EP3445372B1 (https=) |
| JP (1) | JP2019515915A (https=) |
| KR (1) | KR102407053B1 (https=) |
| CN (3) | CN110200978B (https=) |
| AU (2) | AU2017252122B2 (https=) |
| BR (1) | BR112018071559B1 (https=) |
| CA (1) | CA3021677C (https=) |
| MX (1) | MX2018012904A (https=) |
| WO (1) | WO2017185083A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3445373B1 (en) | 2016-04-22 | 2024-08-21 | Viking Therapeutics, Inc. | Use of thyroid beta-agonists |
| US11752161B2 (en) | 2020-03-27 | 2023-09-12 | Gannex Pharma Co., Ltd. | Pharmaceutical compositions, method of making and method of using thereof |
| JP2025520449A (ja) * | 2022-06-15 | 2025-07-03 | バイキング セラピューティクス,インコーポレーテッド | X-ald治療のための甲状腺ベータ作動薬投与計画 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4172896A (en) | 1978-06-05 | 1979-10-30 | Dainippon Pharmaceutical Co., Ltd. | Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same |
| US4968788A (en) | 1986-04-04 | 1990-11-06 | Board Of Regents, The University Of Texas System | Biologically reversible phosphate and phosphonate protective gruops |
| US5091552A (en) | 1986-06-30 | 1992-02-25 | Board Of Regents, The University Of Texas System | Novel antitumor aldophosphamide analogs |
| ATE131825T1 (de) | 1990-06-13 | 1996-01-15 | Arnold Glazier | Phosphorylierte prodrugs |
| US5157027A (en) | 1991-05-13 | 1992-10-20 | E. R. Squibb & Sons, Inc. | Bisphosphonate squalene synthetase inhibitors and method |
| GB9217295D0 (en) | 1992-08-14 | 1992-09-30 | Wellcome Found | Controlled released tablets |
| ATE199906T1 (de) | 1993-06-29 | 2001-04-15 | Mitsubishi Chem Corp | Phosphonat-nukleotid ester-derivate |
| US5541231A (en) | 1993-07-30 | 1996-07-30 | Glaxo Wellcome Inc. | Stabilized Pharmaceutical |
| US5358970A (en) | 1993-08-12 | 1994-10-25 | Burroughs Wellcome Co. | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
| GB9315856D0 (en) | 1993-07-30 | 1993-09-15 | Wellcome Found | Stabilized pharmaceutical |
| DK0999825T3 (da) | 1997-07-29 | 2004-02-09 | Alcon Lab Inc | Oftalmiske sammensætninger indeholdende galactomannanpolymerer og borater |
| US6110973A (en) | 1998-01-29 | 2000-08-29 | Sepracor | Methods for treating obesity and weight gain using optically pure (-)-bupropion |
| US8889112B2 (en) | 1999-09-16 | 2014-11-18 | Ocularis Pharma, Llc | Ophthalmic formulations including selective alpha 1 antagonists |
| US20040091455A1 (en) * | 2002-10-31 | 2004-05-13 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for treatment and management of macular degeneration |
| US6933289B2 (en) | 2003-07-01 | 2005-08-23 | Allergan, Inc. | Inhibition of irritating side effects associated with use of a topical ophthalmic medication |
| CA2534484A1 (en) | 2003-08-07 | 2005-02-17 | Allergan, Inc. | Compositions for delivery of therapeutics into the eyes and methods for making and using same |
| US20050059744A1 (en) | 2003-09-12 | 2005-03-17 | Allergan, Inc. | Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions |
| CA2543132A1 (en) * | 2003-10-23 | 2005-05-19 | Celgene Corporation | Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain |
| CN1882327A (zh) | 2003-11-19 | 2006-12-20 | 症变治疗公司 | 含磷的新的拟甲状腺素药 |
| WO2006128058A2 (en) | 2005-05-26 | 2006-11-30 | Metabasis Therapeutics, Inc. | Thyromimetics for the treatment of fatty liver diseases |
| CA2638753A1 (en) * | 2004-12-08 | 2006-06-15 | Sirion Therapeutics, Inc. | Methods, assays and compositions for treating retinol-related diseases |
| EP1987827A1 (en) * | 2006-02-20 | 2008-11-05 | Takeda Pharmaceutical Company Limited | Novel pharmaceutical |
| WO2011038207A1 (en) | 2009-09-25 | 2011-03-31 | Metabasis Therapeutics, Inc. | Phosphorus-containing thyroid hormone receptor agonists and methods of use |
| HUE038366T2 (hu) * | 2010-08-16 | 2018-10-29 | Allergan Inc | Módszer szabályozó T-sejtek alfa-2B adrenerg receptor agonistákkal való aktiválásához |
| WO2014178892A1 (en) * | 2013-05-03 | 2014-11-06 | Scanlan Thomas S | Use of sobetirome in the treatment of x-linked adrenolenoleukodystrophy |
| EP3259246B1 (en) * | 2015-02-20 | 2023-03-22 | Oregon Health & Science University | Derivatives of sobetirome |
| EP3423379B1 (en) * | 2016-02-29 | 2020-04-01 | Philip Morris Products S.a.s. | Hinge-lid container and blank |
| CN109475121B (zh) * | 2016-05-18 | 2021-06-25 | 俄勒冈健康科学大学 | 苏比替罗衍生物 |
-
2017
- 2017-04-24 CA CA3021677A patent/CA3021677C/en active Active
- 2017-04-24 EP EP17786795.9A patent/EP3445372B1/en active Active
- 2017-04-24 MX MX2018012904A patent/MX2018012904A/es unknown
- 2017-04-24 KR KR1020187033321A patent/KR102407053B1/ko active Active
- 2017-04-24 BR BR112018071559-0A patent/BR112018071559B1/pt active IP Right Grant
- 2017-04-24 CN CN201910397947.3A patent/CN110200978B/zh active Active
- 2017-04-24 JP JP2018555273A patent/JP2019515915A/ja active Pending
- 2017-04-24 AU AU2017252122A patent/AU2017252122B2/en active Active
- 2017-04-24 CN CN201780038675.7A patent/CN109641003A/zh active Pending
- 2017-04-24 CN CN202110804956.7A patent/CN113730421A/zh active Pending
- 2017-04-24 US US16/095,224 patent/US20190134069A1/en not_active Abandoned
- 2017-04-24 WO PCT/US2017/029102 patent/WO2017185083A1/en not_active Ceased
-
2023
- 2023-04-14 AU AU2023202321A patent/AU2023202321B2/en active Active
Non-Patent Citations (1)
| Title |
|---|
| J. Steroid Biochemistry & Molecular Biology, 2009, Vol.116, pp.37-43.* |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017252122A1 (en) | 2018-11-15 |
| EP3445372A4 (en) | 2020-03-25 |
| KR20190017748A (ko) | 2019-02-20 |
| AU2023202321A1 (en) | 2023-05-11 |
| CA3021677C (en) | 2024-11-12 |
| BR112018071559B1 (pt) | 2024-02-06 |
| CN113730421A (zh) | 2021-12-03 |
| WO2017185083A1 (en) | 2017-10-26 |
| CN110200978A (zh) | 2019-09-06 |
| US20190134069A1 (en) | 2019-05-09 |
| AU2023202321B2 (en) | 2025-04-24 |
| AU2017252122B2 (en) | 2023-02-09 |
| CA3021677A1 (en) | 2017-10-26 |
| CN109641003A (zh) | 2019-04-16 |
| EP3445372B1 (en) | 2026-02-25 |
| MX2018012904A (es) | 2019-01-31 |
| EP3445372A1 (en) | 2019-02-27 |
| JP2019515915A (ja) | 2019-06-13 |
| CN110200978B (zh) | 2023-10-31 |
| BR112018071559A2 (pt) | 2019-05-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20181116 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20200423 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20211111 Patent event code: PE09021S01D |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 20220318 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 20220603 Patent event code: PR07011E01D |
|
| PR1002 | Payment of registration fee |
Payment date: 20220607 End annual number: 3 Start annual number: 1 |
|
| PG1601 | Publication of registration |