KR102402444B1 - 대상체가 췌관 선암을 앓을 위험을 평가하기 위한 초기 및 비 침습적 방법 및 이러한 질환의 치료 방법 - Google Patents

대상체가 췌관 선암을 앓을 위험을 평가하기 위한 초기 및 비 침습적 방법 및 이러한 질환의 치료 방법 Download PDF

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KR102402444B1
KR102402444B1 KR1020187027907A KR20187027907A KR102402444B1 KR 102402444 B1 KR102402444 B1 KR 102402444B1 KR 1020187027907 A KR1020187027907 A KR 1020187027907A KR 20187027907 A KR20187027907 A KR 20187027907A KR 102402444 B1 KR102402444 B1 KR 102402444B1
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βig
antibody
pdac
cells
ductal adenocarcinoma
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KR20180120716A (ko
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김인산
삘립 베르또리노
안나 엥니노
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엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔 (인쎄름)
쌩뜨레 나티오날 데 라 르세르쉬 생띠끄
위니베르시테 끌로드 베르나르 리옹 Ⅰ
상뜨로 레옹 베라르
한국과학기술연구원
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    • G01N33/57438—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G01N33/57488—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020187027907A 2016-03-15 2017-03-15 대상체가 췌관 선암을 앓을 위험을 평가하기 위한 초기 및 비 침습적 방법 및 이러한 질환의 치료 방법 Active KR102402444B1 (ko)

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KR1020217014527A KR102408161B1 (ko) 2016-03-15 2017-03-15 대상체가 췌관 선암을 앓을 위험을 평가하기 위한 초기 및 비 침습적 방법 및 이러한 질환의 치료 방법

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EP16305276 2016-03-15
EP16305276.4 2016-03-15
PCT/EP2017/056150 WO2017158043A1 (en) 2016-03-15 2017-03-15 Early and non invasive method for assessing a subject's risk of having pancreatic ductal adenocarcinoma and methods of treatement of such disease

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KR102402444B1 true KR102402444B1 (ko) 2022-05-27

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KR1020217014527A Active KR102408161B1 (ko) 2016-03-15 2017-03-15 대상체가 췌관 선암을 앓을 위험을 평가하기 위한 초기 및 비 침습적 방법 및 이러한 질환의 치료 방법

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EP (2) EP3430404B1 (enExample)
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DK (2) DK3430404T3 (enExample)
ES (2) ES2911038T3 (enExample)
FI (1) FI3779447T3 (enExample)
HR (2) HRP20220335T1 (enExample)
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PL3779447T3 (pl) * 2016-03-15 2023-06-26 INSERM (Institut National de la Santé et de la Recherche Médicale) Sposób aktywowania przeciwnowotworowej odpowiedzi komórek t cd8+ u pacjenta dotknego nowotworem
CN112955462B (zh) * 2018-10-18 2024-05-07 国家医疗保健研究所 用于治疗实体瘤的βIG-H3拮抗剂和免疫检查点抑制剂的组合
KR102169346B1 (ko) * 2019-03-27 2020-10-23 덕성여자대학교 산학협력단 이종이식 동물 모델의 제조방법 및 이종이식 성공 여부 판별 방법
CN118076633A (zh) 2021-07-29 2024-05-24 法国国家健康与医学研究院 人源化抗-人βig-h3蛋白及其用途
WO2025068157A1 (en) * 2023-09-25 2025-04-03 Stromacare COMBINATION OF A βIG-H3 ANTAGONIST AND A PDFG-AA ANTAGONIST FOR THE TREATMENT OF CANCER
WO2025224297A1 (en) * 2024-04-26 2025-10-30 Institut National de la Santé et de la Recherche Médicale Antibodies having specificity to tgfbi and uses thereof

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Publication number Publication date
EP3779447A1 (en) 2021-02-17
KR102408161B1 (ko) 2022-06-13
FI3779447T3 (fi) 2023-04-21
WO2017158043A1 (en) 2017-09-21
EP3430404A1 (en) 2019-01-23
HRP20220335T1 (hr) 2022-05-13
US12140594B2 (en) 2024-11-12
DK3430404T3 (da) 2022-03-21
DK3779447T3 (da) 2023-04-24
EP3430404B1 (en) 2022-01-05
JP2023052360A (ja) 2023-04-11
KR20180120716A (ko) 2018-11-06
HRP20230391T1 (hr) 2023-07-07
KR20210059020A (ko) 2021-05-24
PL3779447T3 (pl) 2023-06-26
US20240159759A1 (en) 2024-05-16
US11740243B2 (en) 2023-08-29
US20190086417A1 (en) 2019-03-21
EP3779447B1 (en) 2023-02-08
JP7569741B2 (ja) 2024-10-18
ES2944259T3 (es) 2023-06-20
JP2019512695A (ja) 2019-05-16
ES2911038T3 (es) 2022-05-17
JP2021119146A (ja) 2021-08-12
PL3430404T3 (pl) 2022-05-02
JP6903680B2 (ja) 2021-07-14

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