KR102398465B1 - 종양의 심층 서열분석 프로파일링 - Google Patents

종양의 심층 서열분석 프로파일링 Download PDF

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KR102398465B1
KR102398465B1 KR1020187023352A KR20187023352A KR102398465B1 KR 102398465 B1 KR102398465 B1 KR 102398465B1 KR 1020187023352 A KR1020187023352 A KR 1020187023352A KR 20187023352 A KR20187023352 A KR 20187023352A KR 102398465 B1 KR102398465 B1 KR 102398465B1
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sample
sequencing
genomic material
capture
amplification
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KR20180098412A (ko
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넬슨 알렉산더
다니엘 버지스
스테이시 스타니슬라프
헤이디 로젠바움
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벤타나 메디컬 시스템즈, 인코포레이티드
에프. 호프만-라 로슈 아게
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/146—Concentration of target or template
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Prostheses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
KR1020187023352A 2016-01-15 2016-11-07 종양의 심층 서열분석 프로파일링 Active KR102398465B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662279126P 2016-01-15 2016-01-15
US62/279,126 2016-01-15
US201662415952P 2016-11-01 2016-11-01
US62/415,952 2016-11-01
PCT/US2016/060835 WO2017123316A1 (en) 2016-01-15 2016-11-07 Deep sequencing profiling of tumors

Publications (2)

Publication Number Publication Date
KR20180098412A KR20180098412A (ko) 2018-09-03
KR102398465B1 true KR102398465B1 (ko) 2022-05-13

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KR1020187023352A Active KR102398465B1 (ko) 2016-01-15 2016-11-07 종양의 심층 서열분석 프로파일링

Country Status (12)

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US (2) US11649492B2 (enExample)
EP (1) EP3402896B1 (enExample)
JP (2) JP7232643B2 (enExample)
KR (1) KR102398465B1 (enExample)
CN (1) CN108463559A (enExample)
AU (1) AU2016386032B2 (enExample)
CA (1) CA3011342C (enExample)
IL (1) IL260304B2 (enExample)
SA (1) SA518392005B1 (enExample)
SG (1) SG11201805600VA (enExample)
WO (1) WO2017123316A1 (enExample)
ZA (1) ZA201804322B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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AU2012242847B2 (en) 2011-04-15 2017-01-19 The Johns Hopkins University Safe sequencing system
EP2912468B1 (en) 2012-10-29 2018-09-12 The Johns Hopkins University Papanicolaou test for ovarian and endometrial cancers
WO2017027653A1 (en) 2015-08-11 2017-02-16 The Johns Hopkins University Assaying ovarian cyst fluid
AU2016386032B2 (en) * 2016-01-15 2021-08-12 F. Hoffmann-La Roche Ag Deep sequencing profiling of tumors
IL319255A (en) 2017-08-07 2025-04-01 Univ Johns Hopkins Methods and materials for cancer assessment and treatment
US20200004928A1 (en) 2018-06-29 2020-01-02 Roche Sequencing Solutions, Inc. Computing device with improved user interface for interpreting and visualizing data
CN109234356B (zh) * 2018-09-18 2021-10-08 南京迪康金诺生物技术有限公司 一种构建杂交捕获测序文库的方法及应用
JP7479367B2 (ja) 2018-11-29 2024-05-08 ヴェンタナ メディカル システムズ， インク． 代表的なＤＮＡシーケンシングによる個別化されたｃｔＤＮＡ疾患のモニタリング
JP7340021B2 (ja) 2018-12-23 2023-09-06 エフ． ホフマン－ラ ロシュ アーゲー 予測腫瘍遺伝子変異量に基づいた腫瘍分類
US20220310208A1 (en) 2019-06-13 2022-09-29 Roche Sequencing Solutions, Inc. Systems and methods with improved user interface for interpreting and visualizing longitudinal
IL295297A (en) 2020-02-14 2022-10-01 Univ Johns Hopkins Methods and materials for assessing nucleic acids
EP4342928A4 (en) 2021-05-20 2025-06-11 Agc Inc. PROCESS FOR PRODUCING POLYCARBONATE

Citations (4)

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WO2009099602A1 (en) * 2008-02-04 2009-08-13 Massachusetts Institute Of Technology Selection of nucleic acids by solution hybridization to oligonucleotide baits
WO2012024658A2 (en) 2010-08-20 2012-02-23 IntegenX, Inc. Integrated analysis system
US20150126379A1 (en) 2013-10-28 2015-05-07 The Translational Genomics Research Institute Long insert-based whole genome sequencing
WO2017123316A1 (en) 2016-01-15 2017-07-20 Ventana Medical Systems, Inc. Deep sequencing profiling of tumors

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US4000159A (en) 1974-06-28 1976-12-28 Phillips Petroleum Company Preparation of n,n-disubstituted thioamides
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5176995A (en) 1985-03-28 1993-01-05 Hoffmann-La Roche Inc. Detection of viruses by amplification and hybridization
US20080119367A1 (en) * 2004-12-17 2008-05-22 Mayo Foundation For Medical Education And Research Prognosis of Renal Cell Carcinoma
US7901890B2 (en) * 2007-11-05 2011-03-08 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation
AU2008335362B2 (en) 2007-12-05 2013-07-25 Complete Genomics, Inc. Efficient base determination in sequencing reactions
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JP5757572B2 (ja) 2009-07-03 2015-07-29 国立大学法人 東京大学 癌細胞の存否を判定する方法および癌患者の予後を判定する方法
PL2539450T3 (pl) 2010-02-25 2016-08-31 Advanced Liquid Logic Inc Sposób wytwarzania bibliotek kwasu nukleinowego
BR112013016708B1 (pt) * 2010-12-30 2021-08-17 Foundation Medicine, Inc Otimização de análise multigene de amostras de tumor
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WO2009099602A1 (en) * 2008-02-04 2009-08-13 Massachusetts Institute Of Technology Selection of nucleic acids by solution hybridization to oligonucleotide baits
WO2012024658A2 (en) 2010-08-20 2012-02-23 IntegenX, Inc. Integrated analysis system
US20150126379A1 (en) 2013-10-28 2015-05-07 The Translational Genomics Research Institute Long insert-based whole genome sequencing
WO2017123316A1 (en) 2016-01-15 2017-07-20 Ventana Medical Systems, Inc. Deep sequencing profiling of tumors

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Also Published As

Publication number Publication date
JP2019503182A (ja) 2019-02-07
ZA201804322B (en) 2022-10-26
JP7379418B2 (ja) 2023-11-14
CA3011342C (en) 2023-03-14
AU2016386032A1 (en) 2018-07-12
IL260304B1 (en) 2024-12-01
CA3011342A1 (en) 2017-07-20
EP3402896B1 (en) 2021-03-31
SA518392005B1 (ar) 2022-02-08
KR20180098412A (ko) 2018-09-03
BR112018014349A2 (pt) 2019-02-12
JP7232643B2 (ja) 2023-03-03
US20180320229A1 (en) 2018-11-08
EP3402896A1 (en) 2018-11-21
IL260304B2 (en) 2025-04-01
AU2016386032B2 (en) 2021-08-12
US11649492B2 (en) 2023-05-16
SG11201805600VA (en) 2018-07-30
US20230250476A1 (en) 2023-08-10
JP2021176302A (ja) 2021-11-11
IL260304A (en) 2018-08-30
WO2017123316A1 (en) 2017-07-20
CN108463559A (zh) 2018-08-28

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