SA518392005B1 - تحديد خصائص التسلسل العميق للأورام - Google Patents

تحديد خصائص التسلسل العميق للأورام

Info

Publication number
SA518392005B1
SA518392005B1 SA518392005A SA518392005A SA518392005B1 SA 518392005 B1 SA518392005 B1 SA 518392005B1 SA 518392005 A SA518392005 A SA 518392005A SA 518392005 A SA518392005 A SA 518392005A SA 518392005 B1 SA518392005 B1 SA 518392005B1
Authority
SA
Saudi Arabia
Prior art keywords
tumors
deep sequencing
profiling
amplification cycles
sequencing profiling
Prior art date
Application number
SA518392005A
Other languages
English (en)
Inventor
نيلسون أليكساندر
بيرجس دانيال
ستاسي ستانيسلاو
روزنباوم هايدي
Original Assignee
.فينتانا ميديكال سيستمز، إنك
اف . هوفمان – لا روش ايه جى
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by .فينتانا ميديكال سيستمز، إنك, اف . هوفمان – لا روش ايه جى filed Critical .فينتانا ميديكال سيستمز، إنك
Publication of SA518392005B1 publication Critical patent/SA518392005B1/ar

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/146—Concentration of target or template
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Prostheses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)

Abstract

يتعلق الكشف الحالي في أحد جوانبه بخطوات إعداد متوالية موجهة targeted sequencing workflow، حيث تشتمل عينة مدخلة input sample على كمية كافية من مادة جينومية genomic material يتم توفيرها بحيث يتم استخدام عدد قليل جدًا من دورات التكبير amplification cycles، وقد لا يتم استخدام أي دورات تكبير، قبل إعداد المتوالية sequencing.
SA518392005A 2016-01-15 2018-07-11 تحديد خصائص التسلسل العميق للأورام SA518392005B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662279126P 2016-01-15 2016-01-15
US201662415952P 2016-11-01 2016-11-01

Publications (1)

Publication Number Publication Date
SA518392005B1 true SA518392005B1 (ar) 2022-02-08

Family

ID=57396824

Family Applications (1)

Application Number Title Priority Date Filing Date
SA518392005A SA518392005B1 (ar) 2016-01-15 2018-07-11 تحديد خصائص التسلسل العميق للأورام

Country Status (12)

Country Link
US (2) US11649492B2 (ar)
EP (1) EP3402896B1 (ar)
JP (2) JP7232643B2 (ar)
KR (1) KR102398465B1 (ar)
CN (1) CN108463559A (ar)
AU (1) AU2016386032B2 (ar)
CA (1) CA3011342C (ar)
IL (1) IL260304B2 (ar)
SA (1) SA518392005B1 (ar)
SG (1) SG11201805600VA (ar)
WO (1) WO2017123316A1 (ar)
ZA (1) ZA201804322B (ar)

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* Cited by examiner, † Cited by third party
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WO2014070462A1 (en) 2012-10-29 2014-05-08 The Johns Hopkins University Papanicolaou test for ovarian and endometrial cancers
US11286531B2 (en) 2015-08-11 2022-03-29 The Johns Hopkins University Assaying ovarian cyst fluid
IL260304B2 (en) 2016-01-15 2025-04-01 Ventana Med Syst Inc Creating a depth profile of crops
KR20250047324A (ko) 2017-08-07 2025-04-03 더 존스 홉킨스 유니버시티 암을 평가하고 치료하기 위한 방법 및 재료
US20200004928A1 (en) 2018-06-29 2020-01-02 Roche Sequencing Solutions, Inc. Computing device with improved user interface for interpreting and visualizing data
CN109234356B (zh) * 2018-09-18 2021-10-08 南京迪康金诺生物技术有限公司 一种构建杂交捕获测序文库的方法及应用
EP3887547A1 (en) * 2018-11-29 2021-10-06 Ventana Medical Systems, Inc. Personalized ctdna disease monitoring via representative dna sequencing
WO2020136133A1 (en) 2018-12-23 2020-07-02 F. Hoffmann-La Roche Ag Tumor classification based on predicted tumor mutational burden
WO2020249704A1 (en) 2019-06-13 2020-12-17 F. Hoffmann-La Roche Ag Systems and methods with improved user interface for interpreting and visualizing longitudinal data
WO2021163546A1 (en) 2020-02-14 2021-08-19 The Johns Hopkins University Methods and materials for assessing nucleic acids
JP7856641B2 (ja) 2021-05-20 2026-05-11 Ａｇｃ株式会社 ポリカーボネートの製造方法

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US4000159A (en) 1974-06-28 1976-12-28 Phillips Petroleum Company Preparation of n,n-disubstituted thioamides
US5176995A (en) 1985-03-28 1993-01-05 Hoffmann-La Roche Inc. Detection of viruses by amplification and hybridization
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US20080119367A1 (en) * 2004-12-17 2008-05-22 Mayo Foundation For Medical Education And Research Prognosis of Renal Cell Carcinoma
WO2009061840A1 (en) * 2007-11-05 2009-05-14 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation
SG193776A1 (en) 2007-12-05 2013-10-30 Complete Genomics Inc Efficient base determination in sequencing reactions
US8592150B2 (en) * 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
WO2009099602A1 (en) * 2008-02-04 2009-08-13 Massachusetts Institute Of Technology Selection of nucleic acids by solution hybridization to oligonucleotide baits
WO2011002029A1 (ja) 2009-07-03 2011-01-06 国立大学法人東京大学 癌細胞の存否を判定する方法および癌患者の予後を判定する方法
JP5882234B2 (ja) 2010-02-25 2016-03-09 アドバンスト リキッド ロジック インコーポレイテッドＡｄｖａｎｃｅｄ Ｌｉｑｕｉｄ Ｌｏｇｉｃ， Ｉｎｃ． 核酸ライブラリーの作製方法
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US20140278461A1 (en) 2013-03-15 2014-09-18 Memorial Sloan-Kettering Cancer Center System and method for integrating a medical sequencing apparatus and laboratory system into a medical facility
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IL260304B2 (en) * 2016-01-15 2025-04-01 Ventana Med Syst Inc Creating a depth profile of crops

Also Published As

Publication number Publication date
WO2017123316A1 (en) 2017-07-20
US12624393B2 (en) 2026-05-12
KR102398465B1 (ko) 2022-05-13
US20230250476A1 (en) 2023-08-10
AU2016386032A1 (en) 2018-07-12
EP3402896B1 (en) 2021-03-31
US11649492B2 (en) 2023-05-16
IL260304B2 (en) 2025-04-01
JP2019503182A (ja) 2019-02-07
CA3011342C (en) 2023-03-14
JP7379418B2 (ja) 2023-11-14
IL260304B1 (en) 2024-12-01
BR112018014349A2 (pt) 2019-02-12
JP7232643B2 (ja) 2023-03-03
EP3402896A1 (en) 2018-11-21
IL260304A (en) 2018-08-30
SG11201805600VA (en) 2018-07-30
ZA201804322B (en) 2022-10-26
KR20180098412A (ko) 2018-09-03
US20180320229A1 (en) 2018-11-08
JP2021176302A (ja) 2021-11-11
CN108463559A (zh) 2018-08-28
CA3011342A1 (en) 2017-07-20
AU2016386032B2 (en) 2021-08-12

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