KR102369544B1 - 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도 - Google Patents

암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도 Download PDF

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KR102369544B1
KR102369544B1 KR1020217012412A KR20217012412A KR102369544B1 KR 102369544 B1 KR102369544 B1 KR 102369544B1 KR 1020217012412 A KR1020217012412 A KR 1020217012412A KR 20217012412 A KR20217012412 A KR 20217012412A KR 102369544 B1 KR102369544 B1 KR 102369544B1
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cancer
transcription factor
dna
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tissue
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KR20210049954A (ko
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제이콥 빈센트 미칼레프
조지 레이스-필류
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벨지언 볼리션 에스피알엘
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    • G01N33/57488—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875—Nucleoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020217012412A 2016-03-22 2017-03-22 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도 Expired - Fee Related KR102369544B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB1604806.8 2016-03-22
GBGB1604806.8A GB201604806D0 (en) 2016-03-22 2016-03-22 Method of identifying a cancer of unknown origin
PCT/EP2017/056851 WO2017162755A1 (en) 2016-03-22 2017-03-22 Use of nucleosome-transcription factor complexes for cancer detection
KR1020187029952A KR102246699B1 (ko) 2016-03-22 2017-03-22 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020187029952A Division KR102246699B1 (ko) 2016-03-22 2017-03-22 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도

Publications (2)

Publication Number Publication Date
KR20210049954A KR20210049954A (ko) 2021-05-06
KR102369544B1 true KR102369544B1 (ko) 2022-03-03

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ID=55968658

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KR1020217012412A Expired - Fee Related KR102369544B1 (ko) 2016-03-22 2017-03-22 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도
KR1020187029952A Expired - Fee Related KR102246699B1 (ko) 2016-03-22 2017-03-22 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도

Family Applications After (1)

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KR1020187029952A Expired - Fee Related KR102246699B1 (ko) 2016-03-22 2017-03-22 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도

Country Status (12)

Country Link
US (1) US20200363418A1 (https=)
EP (3) EP3839513B1 (https=)
JP (1) JP6777757B2 (https=)
KR (2) KR102369544B1 (https=)
CN (1) CN109313192B (https=)
AU (1) AU2017238442A1 (https=)
CA (1) CA3018428C (https=)
ES (2) ES2861440T5 (https=)
GB (1) GB201604806D0 (https=)
MY (1) MY187655A (https=)
SG (1) SG11201807991QA (https=)
WO (1) WO2017162755A1 (https=)

Families Citing this family (5)

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TW202238131A (zh) 2020-11-25 2022-10-01 比利時商比利時意志有限公司 測量無細胞核蛋白染色質片段之方法
TW202242130A (zh) 2020-12-29 2022-11-01 比利時商比利時意志有限公司 循環轉錄因子分析
TW202242145A (zh) 2020-12-29 2022-11-01 比利時商比利時意志有限公司 核小體耗盡循環無細胞染色質片段之轉錄因子結合位點分析
US20240318259A1 (en) * 2021-09-24 2024-09-26 Oncocross Co., Ltd. Method for determining primary tumor site
WO2025073909A1 (en) 2023-10-04 2025-04-10 Belgian Volition Srl Pcr method for detecting ctcf occupied cfdna fragments

Citations (1)

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US20160003848A1 (en) 2013-02-28 2016-01-07 Singapore Volition Pte Limited Method for predicting therapy efficacy using nucleosome structure biomarkers

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CA2404431C (en) * 2000-03-27 2011-06-07 Thomas Jefferson University Guanylyl cyclase c in the detection of stomach and esophageal cancers
EP1425589B1 (en) * 2001-09-14 2007-12-05 F. Hoffmann-La Roche Ag Differential diagnosis of disorders of iron metabolism
US7248921B2 (en) * 2003-06-02 2007-07-24 Cameron Health, Inc. Method and devices for performing cardiac waveform appraisal
US20040018525A1 (en) * 2002-05-21 2004-01-29 Bayer Aktiengesellschaft Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasma
US20040236188A1 (en) * 2003-05-19 2004-11-25 Ge Medical Systems Information Method and apparatus for monitoring using a mathematical model
WO2007025231A2 (en) * 2005-08-26 2007-03-01 The Trustees Of The University Of Pennsylvania Methods using snail transcriptional repressor
US20090298097A1 (en) * 2007-07-17 2009-12-03 Harris Pamela J Methods for the diagnosis of lung cancer
WO2010001933A1 (ja) * 2008-07-01 2010-01-07 学校法人日本大学 標的遺伝子特異的ヒストン修飾制御剤
MY148542A (en) * 2009-06-15 2013-04-30 Cancer Res Initiatives Foundation A method for the assessment of cancer in a biological sample obtained from a subject
EP2270510A1 (en) * 2009-07-02 2011-01-05 EMBL (European Molecular Biology Laboratory) Diagnostic method for predicting the risk of cancer recurrence based on Histone macroH2A isoforms
GB201115098D0 (en) * 2011-09-01 2011-10-19 Belgian Volition Sa Method for detecting nucleosomes containing histone variants
GB201115095D0 (en) * 2011-09-01 2011-10-19 Singapore Volition Pte Ltd Method for detecting nucleosomes containing nucleotides
PT2788767T (pt) * 2011-12-07 2017-12-06 Belgian Volition Sprl Método de detecção de adutos de nucleosoma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160003848A1 (en) 2013-02-28 2016-01-07 Singapore Volition Pte Limited Method for predicting therapy efficacy using nucleosome structure biomarkers

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Ballare Cecilia et al, Molecular Cell (2012.11.21.), vol 49, no 1, pp 67-79.
Paschalia Pantazi et al, Research and Reports in Biochemistry (2015.01.13.), 2015: 5, pp 11-30.

Also Published As

Publication number Publication date
CA3018428C (en) 2024-03-19
ES2861440T5 (en) 2025-02-05
US20200363418A1 (en) 2020-11-19
AU2017238442A1 (en) 2018-10-11
ES2951136T3 (es) 2023-10-18
EP3433616A1 (en) 2019-01-30
EP3433616B1 (en) 2020-12-30
CA3018428A1 (en) 2017-09-28
MY187655A (en) 2021-10-07
EP3433616B2 (en) 2024-07-24
GB201604806D0 (en) 2016-05-04
CN109313192B (zh) 2022-07-26
KR20210049954A (ko) 2021-05-06
EP3839513A1 (en) 2021-06-23
KR102246699B1 (ko) 2021-05-04
EP3839513C0 (en) 2023-06-14
EP4270007A2 (en) 2023-11-01
ES2861440T3 (es) 2021-10-06
CN109313192A (zh) 2019-02-05
SG11201807991QA (en) 2018-10-30
JP2019510974A (ja) 2019-04-18
JP6777757B2 (ja) 2020-10-28
KR20190013707A (ko) 2019-02-11
EP3839513B1 (en) 2023-06-14
EP4270007A3 (en) 2023-12-20
WO2017162755A1 (en) 2017-09-28

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